CN103877344A - Sea cucumber containing traditional Chinese medicinal preparation for treating epilepsy - Google Patents

Sea cucumber containing traditional Chinese medicinal preparation for treating epilepsy Download PDF

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CN103877344A
CN103877344A CN201410144643.3A CN201410144643A CN103877344A CN 103877344 A CN103877344 A CN 103877344A CN 201410144643 A CN201410144643 A CN 201410144643A CN 103877344 A CN103877344 A CN 103877344A
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chinese medicinal
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郑家园
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Abstract

The invention discloses a sea cucumber containing traditional Chinese medicinal preparation for treating epilepsy. A preparation method of the traditional Chinese medicinal preparation comprises the following steps: adding inula flowers, dayflowers, bunge cherry seeds, equisetum hyemale, Chinese pulsatilla root, allium macrostemon, mangnolia officinalis flowers and ash bark in a decocting appliance; adding clean water consistent with a domestic drinking water standard to soak the materials for half an hour, wherein the added water shall be 2-3cm above a medicine level; boiling through strong fire and decocting through slow fire for half an hour; removing internal organs of the sea cucumber and cleaning the sea cucumber, decocting the sea cucumber in the decocting appliance for half an hour, removing dregs and reserving a decoction to obtain the traditional Chinese medicinal preparation. The traditional Chinese medicinal preparation disclosed by the invention, compared to the prior art, is good in curative effect, short in treatment course, low in side effect, convenient to use and low in cost; the traditional Chinese medicinal preparation is an active ingredient extracted from natural animal and plant compositions through long-term exploration and on the basis of private experiences; the traditional Chinese medicinal preparation is safe and reliable to use, and free from toxic and side effect.

Description

A kind of Chinese medicine preparation of the treatment epilepsy that contains Stichopus japonicus composition
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine preparation of the treatment epilepsy that contains Stichopus japonicus composition.
Background technology
Epileptics is a kind of global commonly encountered diseases, frequently-occurring disease, and current global patient reaches more than 7,000 ten thousand people, wherein more than China patient approximately 9,000,000 people.Epilepsy is commonly called as " sheep is insane crazy ", " epilepsy ", has local title " shading crazy " etc., also usually by popular being called of people " convulsion ".Epilepsy refers to abnormal and excessive supersynchronousization of the brain neuron clinical picture causing that discharges.Be characterized in suddenly and one cross property symptom due to the neuron of the paradoxical discharge position difference in brain, and have the diversified form of expression.When morbidity, general consciousness is all lost, and eyes upwards turn over, spit out white foams, and loss of consciousness, that exhales does not answer, and gatism, can bite tongue sometimes, takes out rear fall asleep more.Convulsion general persistence is not long, several seconds at least, and several minutes at most, be generally no more than 15 minutes, severe patient can be twitched repeatedly repeatedly, or continues tens of minutes incessantly, is called status epilepticus.Epileptics is a kind of chronic persistent ailment, and state of an illness complexity, touching difficulty heal, have the title of " not completely annihilated disease ".
Due to cause of disease complexity, outbreak repeatedly, is difficult to radical cure, and epileptics has caused the misery on great body & mind to patient and household thereof.Treatment epileptics is mainly used Western medicine and operation at present, and Western medicine is as phenytoin Sodium, sodium valproate, carbamazepine, clonazepam etc.Western medicine can of short duration elimination symptom, and delays the time that symptom occurs again.But it has brought serious side effect simultaneously, the Western medicine of taking as usual easily causes cerebellar syndrome, and dystropy is drowsiness, dull expression, hypomnesis, the psychological problems such as aggressive behavior and anxiety.Western medicine also has damage in various degree to liver, show as nauseating, vomiting, appetite decline, unable etc.In addition, use the western medicine epileptics length course for the treatment of, weak curative effect, dependency is strong, medical expense is high.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides the Chinese medicine preparation of a kind of good effect, short treating period, side effect is little, easy to use, cost is low treatment epilepsy.Specifically be achieved by the following technical solution:
A kind of Chinese medicine preparation preparation method of the treatment epilepsy that contains Stichopus japonicus composition is: take Stichopus japonicus 5 ~ 10 weight portions, Flos Inulae 5 ~ 30 weight portions, Herba Commelinae 5 ~ 30 weight portions, Semen Pruni 5 ~ 30 weight portions, Herba Equiseti Hiemalis's 5 ~ 30 weight portions, the Radix Pulsatillae 5 ~ 30 weight portions, Bulbus Allii Macrostemonis 5 ~ 30 weight portions, Flos Magnoliae Officinalis 5 ~ 30 weight portions, Cortex Fraxini 5 ~ 30 weight portions; Above-mentioned Flos Inulae, Herba Commelinae, Semen Pruni, Herba Equiseti Hiemalis, the Radix Pulsatillae, Bulbus Allii Macrostemonis, Flos Magnoliae Officinalis, Cortex Fraxini are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction.
Therapeutic Method: every day potion, take at twice; Take continuously treatment 30 days.
Drug action mechanism of the present invention is as follows:
Stichopus japonicus: Echinodermata, Holothuroidea, the common name of Holothuroidea animal, is important oceanic invertebrate.Sea cucumber nutrient is abundant, and body contains the compositions such as protein, fat, vitamin, various trace elements, colloid, holotoxin, acid mucopolysaccharide, but not containing cholesterol.Qing Dynasty's supplementary Amplifications of the Compendium of Materia Medica Chinese medicine ancient books and records record " Stichopus japonicus benefit warm in nature, sufficient enemy joins therefore named Stichopus japonicus; Sweet-salty, the kidney invigorating warp, beneficial marrow, expectorant is prolonged, and takes the photograph urine, flaccidity is treated in tonifying YANG, kills skin ulcer worm ".Successively there is in recent years the traditional Chinese medical science to propose Stichopus japonicus alone or prescription therapeutic tumor, aplastic anemia and diabetes, obtain good result, assisting a ruler in governing a country as commonly encountered diseases treatments such as epilepsy, gastric and duodenal ulcers, chronic viral hepatitis B hepatitis, chronic nephritis, hypertension, pulmonary tuberculosis, neurasthenia's phlebothrombosis, hemorrhoid, proctoptosis and constipation simultaneously, and for general after being ill or in the various medicated diet or diet therapy formulation worked out in postpartum recovery process, Stichopus japonicus has all obtained admitting widely and applying.
Flos Inulae: [another name] revolves and cover China, money, Xia Ju.The head inflorescence of [source] feverfew Flos Inulae.[meridian distribution of property and flavor] slightly warm in nature, bitter in the mouth, pungent, salty.Return lung meridian, stomach warp.[effect and effect] sending down the abnormal ascending QI, expectorant, Hang Shui, preventing or arresting vomiting.Belong to the medicine for warming and resolving cold-phlegm of classifying under expectorants, antitussives and anti-asthmatics medicine.3 ~ 9 grams of [clinical practice] consumptions, decoct soup for oral administration, and it is hard that treatment cough due to wind and cold, phlegm retention are held knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, following painful abdominal mass.Decoct a drug wrapped.
Herba Commelinae: [another name] Bambusicolae thoracicae grass, ground Rhizoma Nelumbinis, duck food grass.The aerial parts of [source] Commelianaceae plant Herba Commelinae.[meridian distribution of property and flavor] is cold in nature, sweet in the mouth, light.Return lung meridian, stomach warp, urinary bladder channel.[effect and effect] heat-clearing and toxic substances removing, inducing diuresis to remove edema.Belong to the heat and toxic materials clearing away medicine of classifying under antipyretic.15 ~ 30 grams of [clinical practice] consumptions, 60 ~ 90 grams of fresh goods, take orally and decoct soup, or smash juice, treatment flu, hyperpyrexia, laryngopharynx swelling and pain, edema oliguria, the puckery pain of pyretic stranguria, carbuncle furunculosis.External: smash and apply or smash juice point larynx.
Semen Pruni: [another name] Wu Lanai core, semen pruni humilidis et japonicae.The seed of [source] rosaceous plant Prunus humilis.[meridian distribution of property and flavor] property is flat, acrid in the mouth, hardship, sweet.Return spleen channel, large intestine channel, small intestine meridian.[effect and effect] cathartic, diuresis.Belong to the laxative drug of purgatives medicine classification.[clinical practice] is used for the treatment of the diseases such as constipation, edema, oliguria.3 ~ 9 grams of consumptions.Anemia of pregnant woman is cautious use of.
Herba Equiseti Hiemalis: [another name] file grass, nib grass, Herba Clinopodii Polycephali.[source] Equisetaceae plant Herba Equiseti Hiemalis's herb.[meridian distribution of property and flavor] property is flat, sweet in the mouth, hardship.Return lung meridian, Liver Channel.[effect and effect] wind-dispelling heat-dissipating, nebula removing, hemostasis.Belong to the pungent and cold medicine for relieving the exterior syndrome of classifying under diaphoretic medicine.[clinical practice] for conjunctival congestion and swelling pain, order raw nebula, epiphora induced by wind, laryngalgia, carbuncle, have blood in stool, dysentery, proctoptosis, metrorrhagia.For oral administration, decoct soup, 3 ~ 9 grams of consumptions.
The Radix Pulsatillae: [another name] old man palpus, Bai Tougong, Radix Pulsatillae grass.The root of [source] ranunculaceae plant Radix Pulsatillae.[meridian distribution of property and flavor] is cold in nature, bitter in the mouth.Return stomach warp, large intestine channel.[effect and effect] heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, in addition, also have the effects such as anti-trichomonal, calmness, analgesia.Belong to the heat removing and blood cooling medicine of classifying under antipyretic.10 ~ 15 grams of [clinical practice] consumptions, take orally and decoct soup, or it is loose to enter ball, treatment bacillary dysentery, amebic dysentery, nose bleeding, bleeding hemorrhoids etc.Suitable amount used externally, smashes deposited.Deficiency and coldness dysentery person avoids clothes.Treatment protozoal dysentery: 15 ~ 30 grams, Radix Pulsatillae rhizome, decocting divides clothes 3 times, within 7 days, is a course for the treatment of; Treatment bacillary dysentery: 15 grams of the Radix Pulsatillaes, 9 grams of Cortex Phellodendris, 5 grams of Cortex Fraxinis, each 2.5 grams of the Radix Aucklandiae, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, be decocted in water for oral dose.
Bulbus Allii Macrostemonis: [another name] Chinese onion Gen, Allium chinensis G. Don, little DUSUAN.The bulb of [source] liliaceous plant Allium macrostemon.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth, hardship.Return lung meridian, stomach warp, large intestine channel.[effect and effect] activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.Belong to QI regulating medicine.5 ~ 9 grams of [clinical practice] consumptions, take orally and decoct soup, or people's ball is loose, heavy after treatment thoracic obstruction pain, phlegm retention cough with asthma, dysentery.External, smashes and applies or smash juice painting.
Flos Magnoliae Officinalis: [another name] spoon flower.The alabastrum of [source] Drymotaenium miyoshianum (Mak.) Mak. tannin plant magnolia officinalis rehd.et wils.var.biloba rehd.et wils..[meridian distribution of property and flavor] is warm in nature, bitter in the mouth.Return spleen, stomach warp.[effect and effect] removing dampness by means of aromatics, regulating the flow of QI to ease the stomach.Belong to damp-resolving medicinal.3~6 grams of [clinical practice] consumptions.By distension and fullness in the abdomen, the pain etc. of controlling retention of damp leading to blockage of QI.
Cortex Fraxini: [another name] wax tree skin, the Rhizoma Euonymus, of Qin Ash skin.Branch skin or the dried bark of [source] Oleaceae plants point leaf Chinese ash.[meridian distribution of property and flavor] is cold in nature, bitter in the mouth, puckery.Return Liver Channel, gallbladder meridian, large intestine channel.[effect and effect] heat clearing and damp drying, astringent therapy, improving eyesight.Belong to the heat clearing and dampness removing medicine of antipyretic subordinate classification.6 ~ 12 grams of [clinical practice] consumptions, are decocted in water for oral dose.Suitable amount used externally, decocts and washes affected part.With controlling hematodiarrhoea, have loose bowels, leucorrhea with red and white discharge, conjunctival congestion and swelling pain, the raw nebula film of order.
Chinese medicine preparation of the present invention has eliminates phlegm for resuscitation, the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., spleen benefiting and stimulating the appetite, the function of benefiting essence and marrow.Chinese medicine preparation of the present invention cures mainly epilepsy; What applicable epilepsy caused faints suddenly, slobbering, gnathospasma, the words of breaking by the teeth, platycoria, the eyes turning upwards, incontinence of urination and defecation, tic of the limbs, or mouthful in send the cry etc. of similar pig sheep, after waking up, feel more from head to foot tired, just like ordinary person, outbreak often, unconsciousness Chu when outbreak.
The Chinese medicine preparation beneficial effect for the treatment of epilepsy of the present invention is: good effect, short treating period, side effect is little, easy to use, cost is low, the present invention is by long-term exploration, in conjunction with experience among the people, develop the active component extracting from natural animal-plant compositions, safe and reliable, have no side effect.
 
Detailed description of the invention
Embodiment 1:
Take Stichopus japonicus 5g, Flos Inulae 30g, Herba Commelinae 5g, Semen Pruni 30g, Herba Equiseti Hiemalis 5g, Radix Pulsatillae 30g, Bulbus Allii Macrostemonis 5g, Flos Magnoliae Officinalis 30g, Cortex Fraxini 5g; Above-mentioned Flos Inulae, Herba Commelinae, Semen Pruni, Herba Equiseti Hiemalis, the Radix Pulsatillae, Bulbus Allii Macrostemonis, Flos Magnoliae Officinalis, Cortex Fraxini are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Embodiment 2:
Take Stichopus japonicus 10g, Flos Inulae 5g, Herba Commelinae 30g, Semen Pruni 5g, Herba Equiseti Hiemalis 30g, Radix Pulsatillae 5g, Bulbus Allii Macrostemonis 30g, Flos Magnoliae Officinalis 5g, Cortex Fraxini 30g; Above-mentioned Flos Inulae, Herba Commelinae, Semen Pruni, Herba Equiseti Hiemalis, the Radix Pulsatillae, Bulbus Allii Macrostemonis, Flos Magnoliae Officinalis, Cortex Fraxini are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Embodiment 3:
Take Stichopus japonicus 8g, Flos Inulae 18g, Herba Commelinae 17g, Semen Pruni 18g, Herba Equiseti Hiemalis 17g, Radix Pulsatillae 18g, Bulbus Allii Macrostemonis 17g, Flos Magnoliae Officinalis 18g, Cortex Fraxini 17g; Above-mentioned Flos Inulae, Herba Commelinae, Semen Pruni, Herba Equiseti Hiemalis, the Radix Pulsatillae, Bulbus Allii Macrostemonis, Flos Magnoliae Officinalis, Cortex Fraxini are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Clinical data:
To Anhui 300, routine epileptic carries out clinical observation treatment, wherein male's 156 examples, and women's 144 examples, the age 16 is to 56 years old, 37 years old mean age.Be divided into immediately 3 treatment groups, every group of 100 people, treatment group 1 adopts the lotion for treatment of embodiment 1; Treatment group 2 adopts the lotion for treatment of embodiment 2; Treatment group 3 adopts the lotion for treatment of embodiment 3.
(1) Therapeutic Method:
Every day, potion, took at twice; Take continuously treatment 30 days.
(2) efficacy assessment standard: with reference to reference to the ordered antiepileptic (Western medicine) of 1979 Qingdao meetings evaluation of clinical curative effect standard on probation, divide level Four evaluation.
Effective: after medication, epilepsy control, or attack times reduces more than 75% before treatment in same period, and when outbreak, symptom and persistent period all obviously alleviate and shorten, electroencephalogram improvement.
Effective: after medication, epilepsy number of times reduces 50%~75% before treatment in same period, there be alleviating and shortening in various degree outbreak symptom and the persistent period, and electroencephalogram is slightly improved.
Heterodyne: after medication, epilepsy number of times reduces less than 50% before treatment in same period, and outbreak symptom and time are not improved, and electroencephalogram is unchanged.
Invalid: after medication, number of times, the clinical symptoms etc. of epilepsy is all unchanged, even trend is serious.
(3) therapeutic effect:
Treatment group 1: effective 65 examples, account for 65%; Effective 34 examples, account for 34%; Heterodyne 1 example, accounts for 1%; Invalid 0 example; Total effective rate 99%;
Treatment group 2: effective 94 examples, account for 94%; Effective 6 examples, account for 6%; Heterodyne 0 example; Invalid 0 example; Total effective rate 100%;
Treatment group 3: effective 69 examples, account for 69%; Effective 28 examples, account for 28%; Heterodyne 3 examples, account for 3%; Invalid 0 example; Total effective rate 97%.
The above, be only preferred embodiment of the present invention, is not intended to limit protection scope of the present invention.One skilled in the art will appreciate that protection scope of the present invention is as the criterion with appending claims.

Claims (1)

1. contain a Chinese medicine preparation for the treatment epilepsy of Stichopus japonicus composition, it is characterized in that preparation method is: take Stichopus japonicus 5 ~ 10 weight portions, Flos Inulae 5 ~ 30 weight portions, Herba Commelinae 5 ~ 30 weight portions, Semen Pruni 5 ~ 30 weight portions, Herba Equiseti Hiemalis's 5 ~ 30 weight portions, the Radix Pulsatillae 5 ~ 30 weight portions, Bulbus Allii Macrostemonis 5 ~ 30 weight portions, Flos Magnoliae Officinalis 5 ~ 30 weight portions, Cortex Fraxini 5 ~ 30 weight portions; Above-mentioned Flos Inulae, Herba Commelinae, Semen Pruni, Herba Equiseti Hiemalis, the Radix Pulsatillae, Bulbus Allii Macrostemonis, Flos Magnoliae Officinalis, Cortex Fraxini are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction.
CN201410144643.3A 2014-04-11 2014-04-11 Sea cucumber containing traditional Chinese medicinal preparation for treating epilepsy Pending CN103877344A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860834A (en) * 2014-04-11 2014-06-18 郑家园 Sea cucumber ingredient containing traditional Chinese medicine preparation for treating epilepsy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101401854A (en) * 2008-10-31 2009-04-08 张江元 Medicament formulation for treating epilepsy and preparation thereof

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101401854A (en) * 2008-10-31 2009-04-08 张江元 Medicament formulation for treating epilepsy and preparation thereof

Non-Patent Citations (2)

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Title
司富春等: "癫痫证候和方药分布规律文献分析", 《中医杂志》 *
朱欧鸰等: "单纯中药治疗癫痫病的研究进展", 《世界中西医结合杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860834A (en) * 2014-04-11 2014-06-18 郑家园 Sea cucumber ingredient containing traditional Chinese medicine preparation for treating epilepsy
CN103860834B (en) * 2014-04-11 2016-05-11 朱长怀 A kind of Chinese medicine preparation for the treatment of epilepsy

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