CN103848783B - 一种一步氧化合成2-氯烟酸的方法 - Google Patents
一种一步氧化合成2-氯烟酸的方法 Download PDFInfo
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- CN103848783B CN103848783B CN201410015351.XA CN201410015351A CN103848783B CN 103848783 B CN103848783 B CN 103848783B CN 201410015351 A CN201410015351 A CN 201410015351A CN 103848783 B CN103848783 B CN 103848783B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
- C07D213/807—Processes of preparation by oxidation of pyridines or condensed pyridines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
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Priority Applications (1)
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CN201410015351.XA CN103848783B (zh) | 2014-01-14 | 2014-01-14 | 一种一步氧化合成2-氯烟酸的方法 |
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CN201410015351.XA CN103848783B (zh) | 2014-01-14 | 2014-01-14 | 一种一步氧化合成2-氯烟酸的方法 |
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CN103848783A CN103848783A (zh) | 2014-06-11 |
CN103848783B true CN103848783B (zh) | 2016-05-04 |
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CN201410015351.XA Active CN103848783B (zh) | 2014-01-14 | 2014-01-14 | 一种一步氧化合成2-氯烟酸的方法 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104513198A (zh) * | 2014-11-29 | 2015-04-15 | 南京红太阳生物化学有限责任公司 | 一种2-氯烟酸的合成方法 |
CN106243028A (zh) * | 2016-07-28 | 2016-12-21 | 南京红太阳生物化学有限责任公司 | 一种一步氧化合成2‑氯烟酸的方法 |
CN109836376B (zh) * | 2019-04-10 | 2022-03-22 | 江苏汉阔生物有限公司 | 一种以2,3-吡啶二羧酸为原料制备2-氯代烟酸的方法 |
CN111153853B (zh) * | 2020-01-03 | 2022-05-24 | 南京红太阳生物化学有限责任公司 | 一种2-氯烟酸的制备方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES501988A0 (es) * | 1981-05-07 | 1982-04-01 | Lisac S A | Procedimiento de obtencion del acido 2-cloro-3-piridin-car- boxilico |
CN1962637A (zh) * | 2006-11-27 | 2007-05-16 | 中国科学院新疆理化技术研究所 | 臭氧化制备烟酸的方法 |
CN101056857A (zh) * | 2004-11-05 | 2007-10-17 | 弗·哈夫曼-拉罗切有限公司 | 异烟酸衍生物的制备方法 |
WO2008077769A1 (en) * | 2006-12-20 | 2008-07-03 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Process for the safe ozonolysis of organic compounds in flammable solvents |
CN101602713A (zh) * | 2009-07-21 | 2009-12-16 | 南京第一农药集团有限公司 | 一种2-氯烟酸合成新方法 |
CN101602717A (zh) * | 2009-07-21 | 2009-12-16 | 南京第一农药集团有限公司 | 一种合成2-氯烟酸的方法 |
CN102584695A (zh) * | 2012-01-13 | 2012-07-18 | 江苏中邦制药有限公司 | 一种5-甲基烟酸的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL62402A0 (en) * | 1980-03-24 | 1981-05-20 | Sterling Drug Inc | Imidazo(4,5-b)pyridines,their preparation and pharmaceutical compositions containing them |
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2014
- 2014-01-14 CN CN201410015351.XA patent/CN103848783B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES501988A0 (es) * | 1981-05-07 | 1982-04-01 | Lisac S A | Procedimiento de obtencion del acido 2-cloro-3-piridin-car- boxilico |
CN101056857A (zh) * | 2004-11-05 | 2007-10-17 | 弗·哈夫曼-拉罗切有限公司 | 异烟酸衍生物的制备方法 |
CN1962637A (zh) * | 2006-11-27 | 2007-05-16 | 中国科学院新疆理化技术研究所 | 臭氧化制备烟酸的方法 |
WO2008077769A1 (en) * | 2006-12-20 | 2008-07-03 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Process for the safe ozonolysis of organic compounds in flammable solvents |
CN101602713A (zh) * | 2009-07-21 | 2009-12-16 | 南京第一农药集团有限公司 | 一种2-氯烟酸合成新方法 |
CN101602717A (zh) * | 2009-07-21 | 2009-12-16 | 南京第一农药集团有限公司 | 一种合成2-氯烟酸的方法 |
CN102584695A (zh) * | 2012-01-13 | 2012-07-18 | 江苏中邦制药有限公司 | 一种5-甲基烟酸的制备方法 |
Non-Patent Citations (1)
Title |
---|
2-氯盐酸合成工艺研究;聂文娜;《河北化工》;20061031;第29卷(第10期);第14-15页 * |
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Effective date of registration: 20161125 Address after: 210047 Nanjing Chemical Industrial Park, Jiangsu aromatic South Road, No. 168 Patentee after: Nanjing Red Sun Biological Chemical Co., Ltd. Address before: Gaochun County, Nanjing City, Jiangsu province 211300 Yingbin Road No. 6 Patentee before: Red Sun Group Co.,Ltd. Patentee before: Nanjing Redsun Co., Ltd. |
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Effective date of registration: 20180516 Address after: 210047 No. 168 aromatics South Road, Nanjing chemical industry park, Jiangsu Co-patentee after: Nanjing Redsun Co., Ltd. Patentee after: Nanjing Red Sun Biological Chemical Co., Ltd. Address before: 210047 No. 168 aromatics South Road, Nanjing chemical industry park, Jiangsu Patentee before: Nanjing Red Sun Biological Chemical Co., Ltd. |
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