CN103784946B

CN103784946B - A kind of pharmaceutical composition treating condyloma acuminatum

Info

Publication number: CN103784946B
Application number: CN201410056312.4A
Authority: CN
Inventors: 王海英; 郑振杰
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-02-16
Filing date: 2014-02-16
Publication date: 2016-06-08
Anticipated expiration: 2034-02-16
Also published as: CN103784946A

Abstract

The present invention relates to a kind of pharmaceutical composition treating condyloma acuminatum, it is characterised in that its raw material medicines in portions by weight is as follows: Radix Salviae Miltiorrhizae 6��9g, Semen Ricini 9��12g, Squama Manis 3��6g, Matrii Sulfas Exsiccatus 4��6g, spend stone 4��6g of heap of stone, Fructus Gardeniae 6��9g, Herba Hyperici Japonici 4��6g, Herba Artemisiae Anomalae 6��9g, Radix Paeoniae Rubra 4��6g, Herba pterocephali 2��3g. Above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well standby. Interferon: 1,000,000 U subcutaneously or intramuscularly inject, the next day or weekly injection 2 times. Useful effect of Chinese medicine of the present invention is: heat-clearing and toxic substances removing, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, can thoroughly remove the virus under local skin mucosa while dispelling body surface wart body, improves immunity, systematic treating, reaches thorough radical cure and do not recur.

Description

A kind of pharmaceutical composition treating condyloma acuminatum

Technical field

The present invention relates to a kind of pharmaceutical composition treating condyloma acuminatum.

Background technology

Condyloma acuminatum is to be infected the caused sexually transmitted disease (STD) being main manifestations with anus genital area hyperplastic lesions by human papillomavirus (HPV). Mostly betide the young people of 18��50 years old. Approximately pass through two weeks to 8 months, average out to sequela incubation period of 3 months. This disease is relatively conventional, mainly through transmission through sex. The HPV the most often causing condyloma acuminatum has 6,11 etc. HPV is easy survival and reproduction when human body warm moist, therefore external genitalia and crissum are the positions being easiest to infect.

Summary of the invention

Useful effect of Chinese medicine of the present invention is: heat-clearing and toxic substances removing, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, can thoroughly remove the virus under local skin mucosa while removing body surface wart body, improves immunity, systematic treating, reaches thorough radical cure and do not recur.

The technical problem to be solved is to overcome technical deficiency, it is provided that a kind of good effect, short treating period, remission rate is high, and cost is low, a kind of pharmaceutical composition treating condyloma acuminatum having no side effect.

For above-mentioned purpose, a kind of pharmaceutical composition treating condyloma acuminatum, it is characterized in that its raw material medicines in portions by weight is as follows: Radix Salviae Miltiorrhizae 6��9g, Semen Ricini 9��12g, Squama Manis 3��6g, Matrii Sulfas Exsiccatus 4��6g, spend stone 4��6g of heap of stone, Fructus Gardeniae 6��9g, Herba Hyperici Japonici 4��6g, Herba Artemisiae Anomalae 6��9g, Radix Paeoniae Rubra 4��6g, Herba pterocephali 2��3g, above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well standby. Interferon: 1,000,000 U subcutaneously or intramuscularly inject, the next day or weekly injection 2 times.

Radix Salviae Miltiorrhizae bitter in the mouth in Chinese medicine of the present invention, feeble QI is trembled with fear, nontoxic. Enter the heart, spleen two warp. Promoting blood circulation to restore menstrual flow, evacuation of pus granulation promoting, special regulating menstruation arteries and veins, reason iliacus is ached, and tissue regeneration promoting blood removes stagnant blood. " book on Chinese herbal medicine is looked for the truth ": Radix Salviae Miltiorrhizae, book load can enter percardium removing blood stasis with potent drugs one language, has use up Radix Salviae Miltiorrhizae effect. So have opinion its can tissue regeneration promoting antiabortive, regulating menstruation relieving restlessness, sedate of reposing, and all migratory arthralgia, metrorrhagia and leukorrhagia, lump in the abdomen, conjunctival congestion, colic, skin ulcer scabies the disease such as swell and ache. Semen Ricini belongs to the seed of euphorbia plant Semen Ricini, and function cures mainly: detumescence and drawing out poison;Rush down lower intestinal stasis relieving; Dredging collateral profit key. Main swollen ulcer drug; Scrofula, acute mastitis, sore throat, mange tinea skin ulcer, scald, edema distension, traumatic injury. Squama Manis salty in the mouth, cold nature. Return liver, stomach warp. Function with cure mainly: the abdominal mass that disappears of invigorating blood circulation, stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, search wind and removing obstruction in channels. For carbuncle sore tumefacting virus, rheumatic arthralgia .... It is prepared that Matrii Sulfas Exsiccatus is that Natrii Sulfas dries through air slaking. Main sulfur acid sodium. Function with cure mainly: relieving constipation by purgation, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat. External treatment laryngopharynx swelling and pain, aphtha of the mouth and tongue, gingival swelling and pain, conjunctival congestion, carbuncle, erysipelas. Spend stone sour in the mouth of heap of stone, puckery, property put down. Return Liver Channel. Merit Bears with cure mainly: removing stasis to stop bleeding. Fructus Gardeniae heat clearing away, pathogenic fire purging, removing heat from blood. Modern study, has antibacterial, antiinflammatory and the effect for the treatment of soft tissue injury. Herba Hyperici Japonici is the herb of Garcinia maingayii Herba Hyperici Japonici. Clearing away heat-damp and promoting diuresis, removing toxic substances, dissipating blood stasis for subsidence of swelling. Main jaundice due to damp-heat; Carbuncle furuncle and phyma poison, tonsillitis, aphtha, conjunctival congestion and swelling pain, venom, traumatic injury. Bacteriostasis: in vitro tests, Common Pathogenic fungus is had obvious inhibiting effect by Herba Hyperici Japonici decoct. Herba Artemisiae Anomalae this product is the dry herb of goatweed Herba Siphonostegiae. Function with cure mainly: blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, removing heat from blood, hemostasis, clearing away heat-damp and promoting diuresis. Radix Paeoniae Rubra bitter in the mouth, cold in nature. Return spleen, stomach, liver, gallbladder meridian. Function cures mainly: clots absorbing, pain relieving, removing heat from blood, detumescence. For maculae caused by violent heat pathogen, injury from falling down, carbuncle skin infection .... Herba pterocephali this product is Dipsacaceae plant spoon leaf Herba pterocephali. Function with cure mainly: removing toxic substances is except pestilence, and dispel the wind blood stasis dispelling. Oleum Radix Arnebiae (Oleum Radix Lithospermi) has effect of box set, convergence. Above compatibility of drugs, bring out the best in each other.

The present invention follows the prescription principle of the traditional Chinese medical science, and be decocted in water for oral dose use, through clinical application for many years verify, total effective rate 96.7%, cure rate 83.8%, have no side effect.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1: a kind of pharmaceutical composition treating condyloma acuminatum, it is characterised in that its raw material medicines in portions by weight is as follows: Radix Salviae Miltiorrhizae 6��9g, Semen Ricini 9��12g, Squama Manis 3��6g, Matrii Sulfas Exsiccatus 4��6g, spend stone 4��6g of heap of stone, Fructus Gardeniae 6��9g, Herba Hyperici Japonici 4��6g, Herba Artemisiae Anomalae 6��9g, Radix Paeoniae Rubra 4��6g, Herba pterocephali 2��3g. By all levigation end is standby above. Above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well standby. Interferon: 1,000,000 U subcutaneously or intramuscularly inject, the next day or weekly injection 2 times.

Embodiment 2: a kind of pharmaceutical composition treating condyloma acuminatum, it is characterised in that its raw material medicines in portions by weight is as follows: Radix Salviae Miltiorrhizae 9g, Semen Ricini 12g, Squama Manis 3g, Matrii Sulfas Exsiccatus 4g, spend stone 4g of heap of stone, Fructus Gardeniae 9g, Herba Hyperici Japonici 6g, Herba Artemisiae Anomalae 6g, Radix Paeoniae Rubra 6g, Herba pterocephali 2g. Above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well deposited affected part, every day 2 times, each 30 minutes. Interferon: 1,000,000 U subcutaneously or intramuscularly inject, the next day or weekly injection 2 times.

Clinical efficacy is summed up:

One, physical data: we are extensive in clinical practice for many years, treat female patient 66 example, the age at 31��56 years old, average 39.2 years old. Curative effect frequency is good. It is not taken by pregnant women.

Two, diagnostic criteria: sexual contact history or mediate contact infect history, typical case's skin lesion is that the moist position such as genitals or crissum pimple, mamillary, cauliflower form or cockscomb shape meat vegetation, rough surface keratinization occurs. 2. auxiliary examination: Acetic acid test is positive, and nucleic acid hybridization can detect HPV-DNA correlated series, PCR detects visible specificity HPV-DNA and expands zone etc.3. patient has unclean sexual life history or spouse to infect history more, and minority condyloma acuminatum is infected by the apparatus of contact stain, and it is infected that neonate also can pass through birth canal. 1��8 month incubation period not etc., average out to 3 months.

Three, method of administration: above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well standby. , adult every day 1 dose, every dose of pan-fried 200ml, early, evening sub-service, every 10 days was 1 course for the treatment of. Interferon injection: 1,000,000 U subcutaneously or intramuscularly inject 1 month, the next day or weekly injection 2 times.

Four, curative effect judging standard

Cure: clinical symptoms is wholly absent.

Take a turn for the better: clinical symptoms is improved.

Invalid: clinical symptoms is unchanged or increases the weight of.

Five, therapeutic effect: the present invention, for many years in clinical practice, treats 66 example patients, cures 52 examples 83.8%, and take a turn for the better 9 examples, is 12.9%; Invalid 1 example. Total effective rate 96.7%, cure rate 83.8%.

Six, model case

1, Rhizoma Zingiberis Recens ��, female, 32 years old, in June, 2010 went to a doctor. Skin lesion, perineum and crissum mamillary meat vegetation, rough surface keratinization 2 months occur under main suit's breast. Lab testing: Acetic acid test is positive. Patient requests applies 20 doses of external applications of Chinese medicine of the present invention, disturb element injection: 1,000,000 U subcutaneously or intramuscularly inject 1 month, the next day or weekly injection 2 times. Clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year.

2, Lee's ��, female, 39 years old, in JIUYUE, 20110 was gone to a doctor, and main suit has spouse to infect history, and skin lesion, mamillary meat vegetation, rough surface keratinization 2 months occurs in crissum. Lab testing: the acetic acid white experiment positive. Patient requests applies 20 doses of external applications of Chinese medicine of the present invention, disturb element injection: 1,000,000 U subcutaneously or intramuscularly inject 1 month, the next day or weekly injection 2 times. Clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year.

3, high ��, man, 22 years old, in November, 2012 went to a doctor. There is skin lesion, mamillary meat vegetation, rough surface keratinization 2 months in main suit's crissum. Lab testing: Acetic acid test is positive. Patient requests applies 20 doses of external applications of Chinese medicine of the present invention, disturb element injection: 1,000,000 U subcutaneously or intramuscularly inject 1 month, the next day or weekly injection 2 times. Clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year.

Claims

1. the pharmaceutical composition treating condyloma acuminatum, it is characterized in that its raw material medicines in portions by weight is as follows: Radix Salviae Miltiorrhizae 6��9g, Semen Ricini 9��12g, Squama Manis 3��6g, Matrii Sulfas Exsiccatus 4��6g, Ophicalcitum 4��6g, Fructus Gardeniae 6��9g, Herba Hyperici Japonici 4��6g, Herba Artemisiae Anomalae 6��9g, Radix Paeoniae Rubra 4��6g, Herba pterocephali 2��3g, above all levigation end Oleum Radix Arnebiae (Oleum Radix Lithospermi) 50 milliliters are mixed well standby.