CN103751309B - 一种治疗肋间神经痛的中药外用制剂及其制备方法 - Google Patents
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1094290A (zh) * | 1993-03-29 | 1994-11-02 | 梁基金 | 跌打百草膏 |
CN1234269A (zh) * | 1999-04-05 | 1999-11-10 | 陈宪民 | 一种骨痹成药 |
CN1895642A (zh) * | 2005-07-12 | 2007-01-17 | 侯保君 | 一种治疗颈肩腰腿痛的中药组合物及其制备方法 |
CN102626505A (zh) * | 2012-04-12 | 2012-08-08 | 潘文龙 | 基于中草药的按摩膏及其制备方法 |
CN103316320A (zh) * | 2013-07-11 | 2013-09-25 | 于洪磊 | 一种治疗骨病的中药组合物 |
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CN1234269A (zh) * | 1999-04-05 | 1999-11-10 | 陈宪民 | 一种骨痹成药 |
CN1895642A (zh) * | 2005-07-12 | 2007-01-17 | 侯保君 | 一种治疗颈肩腰腿痛的中药组合物及其制备方法 |
CN102626505A (zh) * | 2012-04-12 | 2012-08-08 | 潘文龙 | 基于中草药的按摩膏及其制备方法 |
CN103316320A (zh) * | 2013-07-11 | 2013-09-25 | 于洪磊 | 一种治疗骨病的中药组合物 |
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Title |
---|
赵国岑主任医师辨治急性胁痛经验;侯勇谋等;《中医研究》;19980630;第11卷(第3期);第46-47页 * |
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