CN103736016B - A kind of medicine for the treatment of cyclomastopathy and preparation method thereof - Google Patents

A kind of medicine for the treatment of cyclomastopathy and preparation method thereof Download PDF

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CN103736016B
CN103736016B CN201310751006.8A CN201310751006A CN103736016B CN 103736016 B CN103736016 B CN 103736016B CN 201310751006 A CN201310751006 A CN 201310751006A CN 103736016 B CN103736016 B CN 103736016B
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rhizoma
medicine
radix
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CN103736016A (en
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李政
晋利华
逄锦忠
柴春
黄永文
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Abstract

The invention discloses a kind of medicine for the treatment of cyclomastopathy, this medicine is pure Chinese medicine formula; Described each parts by weight of raw materials proportioning is: Squama Manis preparata 10-30 gram, Radix Angelicae Sinensis 55-80 gram, Hirudo 35-75 gram, Carapax Trionycis 50-100 gram, Scorpio 20-30 gram, Lignum Aquilariae Resinatum 5-15 gram, Radix Panacis Quinquefolii 30-60 gram, Crinis Carbonisatus 80-100 gram, Rhizoma Chuanxiong 5-15 gram, Myrrha 40-70 gram, Olibanum 30-70 gram, Rhizoma Atractylodis 40-150 gram, Borneolum Syntheticum 10-30 gram, Sargassum 10-40 gram, Radix Paeoniae Alba 20-60 gram, Rhizoma Curcumae 15-50 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Semen Vaccariae 10-50 gram and Rhizoma Corydalis 5-15 gram; The medicine of this treatment cyclomastopathy have have no side effect, cure rate is high, not easily recur, and the advantage that selling price is lower.

Description

A kind of medicine for the treatment of cyclomastopathy and preparation method thereof
Technical field
The present invention relates to a kind of medicine and method of work thereof for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is commonly encountered diseases and the frequently-occurring disease of women, multiple with young and middle-aged women, especially with unmarried or not give birth to and dysthymic women the most easily suffers from this disease.Clinically show as master with mastalgia, lump etc., and how to change with menstrual cycle, feelings will, the factor such as to overwork is relevant.Generally obvious before physiological period occurs, can alleviate or disappear after end cycle.Severe patient can be rest pain, causes patient side shoulder, axillary fossa, flank, back pain.Treat the mode of cyclomastopathy in the market all based on doctor trained in Western medicine, adopt the hormone medicines such as oral Operand and tamoxifen, or directly perform the operation, these Drug therapys or operative treatment are all with very large side effect, and recurrence probability is very high, and the Drug therapy of a lot of doctor trained in Western medicine is all control to be main, the curative effect of not effecting a permanent cure, cure probability lower, hormone medicine much used in addition and operation all incur great expense, and cause burden to a lot of patient.
Summary of the invention
The technical problem to be solved in the present invention is to provide that one has no side effect, cure rate is high, not easily recurs, and the medicine of the lower treatment cyclomastopathy of selling price.
For solving the problem, the present invention adopts following technical scheme: a kind of medicine for the treatment of cyclomastopathy, being made primarily of Squama Manis preparata, Radix Angelicae Sinensis, Hirudo, Carapax Trionycis, Scorpio, Lignum Aquilariae Resinatum, Radix Panacis Quinquefolii, Crinis Carbonisatus, Rhizoma Chuanxiong, Myrrha, Olibanum, Rhizoma Atractylodis, Borneolum Syntheticum, Sargassum, the Radix Paeoniae Alba, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, Semen Vaccariae and Rhizoma Corydalis, is pure Chinese medicine formula; Described each parts by weight of raw materials proportioning is: Squama Manis preparata 10-30 gram, Radix Angelicae Sinensis 55-80 gram, Hirudo 35-75 gram, Carapax Trionycis 50-100 gram, Scorpio 20-30 gram, Lignum Aquilariae Resinatum 5-15 gram, Radix Panacis Quinquefolii 30-60 gram, Crinis Carbonisatus 80-100 gram, Rhizoma Chuanxiong 5-15 gram, Myrrha 40-70 gram, Olibanum 30-70 gram, Rhizoma Atractylodis 40-150 gram, Borneolum Syntheticum 10-30 gram, Sargassum 10-40 gram, Radix Paeoniae Alba 20-60 gram, Rhizoma Curcumae 15-50 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Semen Vaccariae 10-50 gram and Rhizoma Corydalis 5-15 gram.
As preferably, described raw material weight proportioning is: Squama Manis preparata 30 grams, Radix Angelicae Sinensis 80 grams, Hirudo 75 grams, Carapax Trionycis 100 grams, Scorpio 30 grams, Lignum Aquilariae Resinatum 15 grams, Radix Panacis Quinquefolii 60 grams, Crinis Carbonisatus 100 grams, Rhizoma Chuanxiong 15 grams, Myrrha 70 grams, Olibanum 70 grams, Rhizoma Atractylodis 150 grams, Borneolum Syntheticum 30 grams, Sargassum 40 grams, the Radix Paeoniae Alba 60 grams, Rhizoma Curcumae 50 grams, Bulbus Fritillariae Thunbergii 15 grams, Semen Vaccariae 50 grams and Rhizoma Corydalis 15 grams.
As preferably, described raw material weight proportioning is: Squama Manis preparata 10 grams, Radix Angelicae Sinensis 55 grams, Hirudo 35 grams, Carapax Trionycis 50 grams, Scorpio 20 grams, Lignum Aquilariae Resinatum 5 grams, Radix Panacis Quinquefolii 30 grams, Crinis Carbonisatus 80 grams, Rhizoma Chuanxiong 5 grams, Myrrha 40 grams, Olibanum 30 grams, Rhizoma Atractylodis 40 grams, Borneolum Syntheticum 10 grams, Sargassum 10 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Curcumae 15 grams, Bulbus Fritillariae Thunbergii 5 grams, Semen Vaccariae 10 grams and Rhizoma Corydalis 5 grams.
As preferably, described raw material weight proportioning is: Squama Manis preparata 20 grams, Radix Angelicae Sinensis 65 grams, Hirudo 50 grams, Carapax Trionycis 75 grams, Scorpio 26 grams, Lignum Aquilariae Resinatum 10 grams, Radix Panacis Quinquefolii 55 grams, Crinis Carbonisatus 90 grams, Rhizoma Chuanxiong 12 grams, Myrrha 56 grams, Olibanum 45 grams, Rhizoma Atractylodis 100 grams, Borneolum Syntheticum 20 grams, Sargassum 25 grams, the Radix Paeoniae Alba 40 grams, Rhizoma Curcumae 30 grams, Bulbus Fritillariae Thunbergii 10 grams, Semen Vaccariae 35 grams and Rhizoma Corydalis 10 grams.
Another technical problem that the present invention will solve is to provide that one has no side effect, cure rate is high, not easily recurs, and the manufacture method of the medicine of the lower treatment cyclomastopathy of selling price.
For solving the problem, the present invention adopts following technical scheme: comprise the following steps:
A, Bulbus Fritillariae Thunbergii and Rhizoma Corydalis are ground to form fine powder;
B, Squama Manis preparata, Radix Angelicae Sinensis, Hirudo, Carapax Trionycis, Scorpio, Lignum Aquilariae Resinatum, Radix Panacis Quinquefolii, Crinis Carbonisatus, Rhizoma Chuanxiong, Myrrha, Olibanum, Rhizoma Atractylodis, Borneolum Syntheticum, Sargassum, the Radix Paeoniae Alba, Rhizoma Curcumae and Semen Vaccariae are decocted with water three times, first time decocts 3-4 hour, second time decocts 2-3 hour, third time decocts 1-2 hour, it is filtered, gets filtrate;
C, the filtrate of getting to be concentrated, make relative density reach 1.2-1.5, leave standstill 24 hours, get supernatant;
D, supernatant is continued to be condensed into thick shape, add the fine powder of Bulbus Fritillariae Thunbergii and Rhizoma Corydalis, be stirred to evenly;
E, leave standstill incapsulated after 18-24 hour, be made into pill.
The beneficial effect that the present invention treats the medicine of liver and gall pancreas spleen is: because the medicine for the treatment of cyclomastopathy adopts pure Chinese medicine to be made, can not have side effects to human body; And several Chinese medicines wherein adopted are all interact, the effect allowing the property of medicine reach best, improves cure rate; In addition, have several Chinese medicine to have among Chinese medicine used in vital base and primordial QI consolidating, the body constitution of human body itself to be carried out to effect of effectively conditioning, allow patient after rehabilitation, have good self immune system, not easily recur; The raw material of Chinese medicine that this invention product adopts is all common raw material, and cost of material is low, therefore controls selling price in popular scope.
Detailed description of the invention
A kind of medicine for the treatment of cyclomastopathy, being made primarily of Squama Manis preparata, Radix Angelicae Sinensis, Hirudo, Carapax Trionycis, Scorpio, Lignum Aquilariae Resinatum, Radix Panacis Quinquefolii, Crinis Carbonisatus, Rhizoma Chuanxiong, Myrrha, Olibanum, Rhizoma Atractylodis, Borneolum Syntheticum, Sargassum, the Radix Paeoniae Alba, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, Semen Vaccariae and Rhizoma Corydalis, is pure Chinese medicine formula; Described each parts by weight of raw materials proportioning is: Squama Manis preparata 10-30 gram, Radix Angelicae Sinensis 55-80 gram, Hirudo 35-75 gram, Carapax Trionycis 50-100 gram, Scorpio 20-30 gram, Lignum Aquilariae Resinatum 5-15 gram, Radix Panacis Quinquefolii 30-60 gram, Crinis Carbonisatus 80-100 gram, Rhizoma Chuanxiong 5-15 gram, Myrrha 40-70 gram, Olibanum 30-70 gram, Rhizoma Atractylodis 40-150 gram, Borneolum Syntheticum 10-30 gram, Sargassum 10-40 gram, Radix Paeoniae Alba 20-60 gram, Rhizoma Curcumae 15-50 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Semen Vaccariae 10-50 gram and Rhizoma Corydalis 5-15 gram.
The preferred weight proportioning of above-mentioned raw materials medicine is as follows:
Embodiment 1, formula:
Squama Manis preparata 30 grams, Radix Angelicae Sinensis 80 grams, Hirudo 75 grams, Carapax Trionycis 100 grams, Scorpio 30 grams, Lignum Aquilariae Resinatum 15 grams, Radix Panacis Quinquefolii 60 grams, Crinis Carbonisatus 100 grams, Rhizoma Chuanxiong 15 grams, Myrrha 70 grams, Olibanum 70 grams, Rhizoma Atractylodis 150 grams, Borneolum Syntheticum 30 grams, Sargassum 40 grams, the Radix Paeoniae Alba 60 grams, Rhizoma Curcumae 50 grams, Bulbus Fritillariae Thunbergii 15 grams, Semen Vaccariae 50 grams and Rhizoma Corydalis 15 grams.
Manufacture method is:
A, Bulbus Fritillariae Thunbergii and Rhizoma Corydalis are ground to form fine powder;
B, Squama Manis preparata, Radix Angelicae Sinensis, Hirudo, Carapax Trionycis, Scorpio, Lignum Aquilariae Resinatum, Radix Panacis Quinquefolii, Crinis Carbonisatus, Rhizoma Chuanxiong, Myrrha, Olibanum, Rhizoma Atractylodis, Borneolum Syntheticum, Sargassum, the Radix Paeoniae Alba, Rhizoma Curcumae and Semen Vaccariae are decocted with water three times, first time decocts 3-4 hour, second time decocts 2-3 hour, third time decocts 1-2 hour, it is filtered, gets filtrate;
C, the filtrate of getting to be concentrated, make relative density reach 1.2-1.5, leave standstill 24 hours, get supernatant;
D, supernatant is continued to be condensed into thick shape, add the fine powder of Bulbus Fritillariae Thunbergii and Rhizoma Corydalis, be stirred to evenly;
E, leave standstill incapsulated after 18-24 hour, be made into pill.
Embodiment 2, formula:
Squama Manis preparata 10 grams, Radix Angelicae Sinensis 55 grams, Hirudo 35 grams, Carapax Trionycis 50 grams, Scorpio 20 grams, Lignum Aquilariae Resinatum 5 grams, Radix Panacis Quinquefolii 30 grams, Crinis Carbonisatus 80 grams, Rhizoma Chuanxiong 5 grams, Myrrha 40 grams, Olibanum 30 grams, Rhizoma Atractylodis 40 grams, Borneolum Syntheticum 10 grams, Sargassum 10 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Curcumae 15 grams, Bulbus Fritillariae Thunbergii 5 grams, Semen Vaccariae 10 grams and Rhizoma Corydalis 5 grams.
Manufacture method is identical with embodiment 1.
Embodiment 3, formula:
Squama Manis preparata 20 grams, Radix Angelicae Sinensis 65 grams, Hirudo 50 grams, Carapax Trionycis 75 grams, Scorpio 26 grams, Lignum Aquilariae Resinatum 10 grams, Radix Panacis Quinquefolii 55 grams, Crinis Carbonisatus 90 grams, Rhizoma Chuanxiong 12 grams, Myrrha 56 grams, Olibanum 45 grams, Rhizoma Atractylodis 100 grams, Borneolum Syntheticum 20 grams, Sargassum 25 grams, the Radix Paeoniae Alba 40 grams, Rhizoma Curcumae 30 grams, Bulbus Fritillariae Thunbergii 10 grams, Semen Vaccariae 35 grams and Rhizoma Corydalis 10 grams.
Manufacture method is identical with embodiment 1.
The primary raw material adopted in the present invention all has unique pharmacology:
Olibanum: blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.The logical circulation of qi promoting of can living of pungent loose temperature is fallen apart stagnant, and be the product that qi depression to blood stasis disease is conventional, be used for various pain disease, clinical application range is very wide.Frequent use can be fallen apart blood evacuation of pus, and ventilationization is stagnant.
Myrrha: promoting blood circulation and stopping pain, detumescence and promoting granulation.Be all resinae medicine with Olibanum, function is close.The two is energy promoting blood circulation and stopping pain, detumescence and promoting granulation all, and blood stasis of ruling together, dysmenorrhea, trusted subordinate are become silted up bitterly, and traumatic injury, be all external wounds staple, right Olibanum is partial to blood-activating and qi-promoting, and blood stasis stagnation of QI person use, Myrrha is then good at the merit of eliminating stasis to stop pain.
Borneolum Syntheticum: have one's ideas straightened out, refreshment, clearing away heat to alleviate pain.Close disease god dizzy, this product acrid in the mouth gas is fragrant, and have the effect of refreshment of having one's ideas straightened out, Borneolum Syntheticum is cool in nature, is the product of waking up the patient from unconsciousness by clearing away heat, is applicable to treatment heat-blockage coma, if with the product compatibility of warm cold relieving, also can treat constipation due to cold pathogen god dizzy.
Squama Manis preparata: salty in the mouth, cold nature.There is effect of dysmenorrhea of invigorating blood circulation, stimulating milk secretion, detumescence and apocenosis.
Radix Angelicae Sinensis: sweet in the mouth, pungent.Warm in nature.Have enrich blood, promoting blood circulation and stopping pain, intestine moistening effect.
Hirudo: salty in the mouth, hardship.Property is put down.There is removing blood stasis by the effect of becoming silted up.
Carapax Trionycis: salty in the mouth.Cold in nature.There is effect of nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving.
Scorpio: acrid in the mouth.Property is put down.Slightly poisonous.There is effect of relieving spasm by subduing liver-wind, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain.
Lignum Aquilariae Resinatum: acrid in the mouth, hardship.Warm in nature.There are promoting the circulation of QI to relieve pain, sending down the abnormal ascending QI adjust in, effect of the kidney warming improving inspiration by invigorating kidney-QI.
Radix Panacis Quinquefolii: bitter in the mouth.Cold nature.There is boosting qi and nourishing yin, effect that quench promotes the production of body fluid.
Experimental example:
MethodsThe cases enrolled 70 example, wherein 40 people male, 30 people women.Be divided into 4 stages the whole course for the treatment of, when each course for the treatment of is one month.
Recovery from illness Effective Effectively Invalid Overall obvious effective rate
First course for the treatment of 0 6 54 10 8.57%
Second course for the treatment of 7 17 39 7 34.28%
3rd course for the treatment of 39 20 9 2 84.28%
4th course for the treatment of 62 4 2 2 94.28%
After the treatment of 4 courses for the treatment of, making regular check on monthly is carried out to 62 patients of recovery from illness, observes the situation having having no side effect and recur further.
Recurrence Apparent side effect Slight side effect Have no side effect Recurrence probability
Four months 1 1 3 57 8.06%
Typical case:
Lin, 30 years old, found oneself to have suffered from cyclomastopathy in 2011, beginning is treated by medicine, find after two wheat harvesting periods that Drug therapy does not have obvious effect, have no alternative and select operation to treat, Post operation about a year, the cyclomastopathy recurrence of Lin, in view of situation before, Lin has this time selected product of the present invention, the Drug therapy of pure Chinese medicine formula, through the treatment of five months, make a definite diagnosis the state of an illness through hospital and cure completely.
The beneficial effect that the present invention treats the medicine of cyclomastopathy is: as can be seen from the form of top, adopts pure Chinese medicine to be made owing to treating the medicine of cyclomastopathy, the side effect produced human body lacking very; And several Chinese medicines wherein adopted are all interact, the effect allowing the property of medicine reach best, improves cure rate; In addition, have several Chinese medicine to have among Chinese medicine used in vital base and primordial QI consolidating, the body constitution of human body itself to be carried out to effect of effectively conditioning, allow patient after rehabilitation, have good self immune system, not easily recur; The raw material of Chinese medicine that this invention product adopts is all common raw material, and cost of material is low, therefore controls selling price in popular scope.
The above, be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, and any change of expecting without creative work or replacement, all should be encompassed within protection scope of the present invention.Therefore, the protection domain that protection scope of the present invention should limit with claims is as the criterion.

Claims (4)

1. treat a medicine for cyclomastopathy, it is characterized in that: be made by Squama Manis preparata, Radix Angelicae Sinensis, Hirudo, Carapax Trionycis, Scorpio, Lignum Aquilariae Resinatum, Radix Panacis Quinquefolii, Crinis Carbonisatus, Rhizoma Chuanxiong, Myrrha, Olibanum, Rhizoma Atractylodis, Borneolum Syntheticum, Sargassum, the Radix Paeoniae Alba, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, Semen Vaccariae and Rhizoma Corydalis; Each raw material weight proportioning is: Squama Manis preparata 10-30 gram, Radix Angelicae Sinensis 55-80 gram, Hirudo 35-75 gram, Carapax Trionycis 50-100 gram, Scorpio 20-30 gram, Lignum Aquilariae Resinatum 5-15 gram, Radix Panacis Quinquefolii 30-60 gram, Crinis Carbonisatus 80-100 gram, Rhizoma Chuanxiong 5-15 gram, Myrrha 40-70 gram, Olibanum 30-70 gram, Rhizoma Atractylodis 40-150 gram, Borneolum Syntheticum 10-30 gram, Sargassum 10-40 gram, Radix Paeoniae Alba 20-60 gram, Rhizoma Curcumae 15-50 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Semen Vaccariae 10-50 gram and Rhizoma Corydalis 5-15 gram.
2. a kind of medicine for the treatment of cyclomastopathy according to claim 1, is characterized in that: described raw material weight proportioning is: Squama Manis preparata 30 grams, Radix Angelicae Sinensis 80 grams, Hirudo 75 grams, Carapax Trionycis 100 grams, Scorpio 30 grams, Lignum Aquilariae Resinatum 15 grams, Radix Panacis Quinquefolii 60 grams, Crinis Carbonisatus 100 grams, Rhizoma Chuanxiong 15 grams, Myrrha 70 grams, Olibanum 70 grams, Rhizoma Atractylodis 150 grams, Borneolum Syntheticum 30 grams, Sargassum 40 grams, the Radix Paeoniae Alba 60 grams, Rhizoma Curcumae 50 grams, Bulbus Fritillariae Thunbergii 15 grams, Semen Vaccariae 50 grams and Rhizoma Corydalis 15 grams.
3. a kind of medicine for the treatment of cyclomastopathy according to claim 1, is characterized in that: described raw material weight proportioning is: Squama Manis preparata 10 grams, Radix Angelicae Sinensis 55 grams, Hirudo 35 grams, Carapax Trionycis 50 grams, Scorpio 20 grams, Lignum Aquilariae Resinatum 5 grams, Radix Panacis Quinquefolii 30 grams, Crinis Carbonisatus 80 grams, Rhizoma Chuanxiong 5 grams, Myrrha 40 grams, Olibanum 30 grams, Rhizoma Atractylodis 40 grams, Borneolum Syntheticum 10 grams, Sargassum 10 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Curcumae 15 grams, Bulbus Fritillariae Thunbergii 5 grams, Semen Vaccariae 10 grams and Rhizoma Corydalis 5 grams.
4. a kind of medicine for the treatment of cyclomastopathy according to claim 1, is characterized in that: described raw material weight proportioning is: Squama Manis preparata 20 grams, Radix Angelicae Sinensis 65 grams, Hirudo 50 grams, Carapax Trionycis 75 grams, Scorpio 26 grams, Lignum Aquilariae Resinatum 10 grams, Radix Panacis Quinquefolii 55 grams, Crinis Carbonisatus 90 grams, Rhizoma Chuanxiong 12 grams, Myrrha 56 grams, Olibanum 45 grams, Rhizoma Atractylodis 100 grams, Borneolum Syntheticum 20 grams, Sargassum 25 grams, the Radix Paeoniae Alba 40 grams, Rhizoma Curcumae 30 grams, Bulbus Fritillariae Thunbergii 10 grams, Semen Vaccariae 35 grams and Rhizoma Corydalis 10 grams.
CN201310751006.8A 2013-12-31 2013-12-31 A kind of medicine for the treatment of cyclomastopathy and preparation method thereof Expired - Fee Related CN103736016B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966321A (en) * 2010-07-13 2011-02-09 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966321A (en) * 2010-07-13 2011-02-09 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicinal composition for treating breast cancer and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
乳腺增生病中药用药规律分析;孙杨;《山东中医杂志》;20120831;第31卷(第8期);544-546 *

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