CN103721337B - Catheter pushed into blood vessel in cooperation with guide wire and manufacturing method thereof - Google Patents

Catheter pushed into blood vessel in cooperation with guide wire and manufacturing method thereof Download PDF

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Publication number
CN103721337B
CN103721337B CN201210393570.2A CN201210393570A CN103721337B CN 103721337 B CN103721337 B CN 103721337B CN 201210393570 A CN201210393570 A CN 201210393570A CN 103721337 B CN103721337 B CN 103721337B
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Prior art keywords
conduit
spiral layers
seal wire
silk
push
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CN103721337A (en
Inventor
徐世云
张琳琳
唐智荣
罗七
罗七一
杨海
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Shanghai Microport Medical Group Co Ltd
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Shanghai Microport Medical Group Co Ltd
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Priority to CN201210393570.2A priority Critical patent/CN103721337B/en
Priority to PCT/CN2013/085274 priority patent/WO2014059922A1/en
Publication of CN103721337A publication Critical patent/CN103721337A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0062Catheters; Hollow probes characterised by structural features having features to improve the sliding of one part within another by using lubricants or surfaces with low friction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M2025/0183Rapid exchange or monorail catheters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention provides a catheter pushed into the blood vessel in cooperation with a guide wire and a manufacturing method of the catheter pushed into the blood vessel in cooperation with the guide wire. A spiral layer is arranged on the inner wall of the catheter. When the catheter is pushed along the guide wire, the motion direction of the guide wire is guaranteed, meanwhile, the cooperation area of the guide wire and the catheter is greatly reduced, friction force between the inner wall of the catheter and the guide wire is reduced, and the performance that the catheter can be pushed is improved.

Description

Cooperation seal wire carries out conduit and its manufacture method of Ink vessel transfusing push
Technical field
The present invention relates to the conduit pushing with seal wire cooperation in conduit, more particularly to arteries.
Background technology
In the operation treating coronary heart disease using invasive procedures, percutaneous puncture transluminal coronary angioplasty art (Percutaneous Transluminal Coronary Angioplasty;PTCA) combine stenter to implant, make narrow hat Shape arterial lumen becomes big, and blood flow increases, and blood supply improves.
Coronary artery bracket implantation detailed process be simply:Percutaneous puncture femoral artery or radial artery, by retrograde for radiography seal wire warp Aorta is delivered at aortic root opening coronarius, sends into angiography catheter along seal wire, exits seal wire, carry out radiography, Radiography finishes, and exits angiography catheter, enters back into radiography seal wire, enters guiding catheter along seal wire, exits radiography seal wire, enters light Sliding guiding wire, delivers to arteria coronaria porch along in guiding catheter, enters coronary artery after going out conduit.Again by the sacculus of belt supporting frame Conduit is placed on seal wire, positioned at guiding catheter intracavity, delivers to arteria coronaria affected area, irrigates making of certain pressure to the sacculus in support Shadow liquid fills, and struts support, and fixed support is in focus narrow positions.
Traditionally, the inwall of the delivery conduit coordinating with smooth seal wire is smooth structure, pushes being wrapped in smooth seal wire When to diseased region, when particularly by vascular bending position, frictional resistance is than larger.
In order to reduce frictional resistance, discontinuous construction can be increased on seal wire surface and process.But, discontinuous construction is processed May result in following defect:
1., when pushing into sacculus dilating catheter along seal wire, the conduit tip head (i.e. the far-end of conduit) of narrow openings exists It is possible to during push to be stuck in seal wire surface and discontinuously locates, lead to push difficult;
2., during seal wire is inserted diseased region, when seal wire head has gone out conduit mouth, enter diseased region, such as narrow When narrow arteria coronaria, its protrusion of surface shape or discontinuous construction may increase propelling resistance, in addition vascular tissue injury and lead to simultaneously Question is inscribed.
Chinese utility model patent CN2824973Y discloses a kind of medical guiding wire.Traditional circle is led by this medical guiding wire The silk alternation of cross-section is triangle, pentagon, hexagon, star etc., even has helicitic texture on seal wire it is therefore an objective to for dropping The cooperation area of low catheter guide wire, thus reduce frictional force.But it is contemplated that seal wire is in the blood vessel, after having gone out angiography catheter, will Directly to advance one section in diseased region, and often this position is inherently narrow, then the change on seal wire surface has increase to damage blood The possibility of pipe.
United States Patent (USP) US6849062B2 discloses a kind of catheter shaft for foley's tube.This catheter shaft is by traditional light Star changed into by sliding conduit, there is a plurality of (at least 4) projection lines, described a plurality of projection lines on the inner periphery of catheter shaft Straight line runs through whole conduit shaft length, and purpose is also the contact area reducing with seal wire.But its shortcoming is:
1. described in, a plurality of projection lines straight line runs through whole conduit shaft length, and the contact between seal wire and catheter shaft remains as Continuous linear contact lay, since it is desired that the range of movement to limit seal wire for a plurality of projection lines, thus increased friction;
2. in crooked position, seal wire is likely to increase the contact with projection, and frictional force still can be very big.
Content of the invention
It is an object of the invention to provide a kind of cooperation seal wire carries out conduit and its manufacture method of Ink vessel transfusing push, lead on edge When silk pushes this conduit, while ensureing guide wire motion direction, greatly reduce the cooperation area of seal wire and conduit, push away in conduit During entering, reduce the frictional force of pipe inner wall and seal wire, increase conduit can pushability.
The present invention provides a kind of cooperation seal wire to carry out the conduit of Ink vessel transfusing push, wherein:The inwall of described conduit has spiral shell Rotation layer;The hardness of described spiral layers is more than the hardness of described conduit;It is characterized in that described spiral layers are selected according to below equation Pitch L:
L<=2*sqrt (3r^2+2R*r)
Wherein r is seal wire radius, and R is the minimum bending radius of described seal wire, and described spiral layers in described conduit Height in the radial direction is taken as r.
Because the inwall of described conduit has spiral layers, the contact between seal wire and conduit is discontinuous linear contact lay or point connects Touch, when pushing this conduit along seal wire, while ensureing guide wire motion direction, greatly reduce the mating surface of seal wire and conduit Long-pending, in conduit progradation, reduce the frictional force of pipe inner wall and seal wire, increase conduit can pushability.According to this formula Select pitch L of described spiral layers, the seal wire being in maximum deflection state can contact two adjacent threads of described spiral layers Top rather than only contact are located at the valley between described two adjacent threads so that be in the seal wire of maximum deflection state with Conduit forms stable three point contact, smoothly to guide conduit.But pitch L is also unsuitable too small, because the too small then spiral shell of pitch L Volution number increases, and contact area increases, and friction increases.
Meanwhile, the present invention change be conduit inner cavity surface structure (towards the side of seal wire), with by change seal wire table Face is compared come the method to reduce cooperation area and to reduce frictional force, by more difficult generation additional friction in propulsion.
Described spiral layers can be distributed in the arbitrary region between the two ends of described conduit.Preferably, described spiral layers Distribution covers whole length of described conduit, so, even if there being the situation blocking seal wire to occur, is also seal wire starting end in vitro Rather than internal, will easily adjust.For example, in rapid exchange balloon conduit, because catheter length is shorter, in operation In, install in vitro conduit on the seal wire after, seal wire will pass from the guidewire port of foley's tube, during pushing, smooth leads Silk will be always maintained at without there being change with the cooperation of conduit, conduit will not be had extra obstruction to occur again.
Preferably, the surface contacting with described seal wire of described spiral layers is towards described seal wire projection, thus subtracting further Few seal wire and the contact area of conduit.It is highly preferred that the leading the described of end towards described seal wire projection of described spiral layers Section on the axial direction of pipe is curved or point-like, thus the contact between seal wire and conduit is point contact, further subtracts Lack the contact area of seal wire and conduit.The axle in described conduit in the end towards described seal wire projection for the described spiral layers To the section on direction curved in the case of, described spiral layers do not allow easy to wear coming off.
Width on the axial direction of described conduit for the section of described spiral layers is unrestricted, if this width ensure with Pipe inner wall combines and is fixed well.It is, however, preferable that the section of described spiral layers is on the axial direction of described conduit Width tapers into towards described seal wire.The possibility blocking seal wire so can be reduced.It is highly preferred that the section of described spiral layers It is generally shaped like arc, triangle, trapezoidal or other polygon.
Preferably, the surface that described spiral layers are contacted with described seal wire has the coating for reducing friction.It is highly preferred that Described coating can include organosilicon;Described coating can include hydrophilic organics hydrophilicity or hydrophobic organic compound.Further excellent Selection of land, described hydrophobic organic compound includes politef (PTFE) or Parylene (PARYLENE).
The height in the radial direction in described conduit of described spiral layers is unrestricted, but preferably slightly smaller than described seal wire Radius.
Preferably, described spiral layers are made up of hard material.It is highly preferred that described hard material is macromolecular material or gold Belong to material.It is further preferred that described hard material is engineering plastics or alloy.It is further preferred that described alloy is not Rust steel or Nitinol.It is further preferred that described engineering plastics are polyamide or polyester.
The present invention also provides a kind of method manufacturing the above-mentioned conduit coordinating seal wire to carry out Ink vessel transfusing push, methods described Including:Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;Make helical form operation silk, described operation The spiral external diameter of silk is matched with the internal diameter of described hollow tubular base material, and the outside of described operation silk has groove, and described behaviour Make the length that silk length in the axial direction is more than described hollow tubular base material;Make spiral layers silk, described spiral layers silk It is dimensioned such that described spiral layers silk can be embedded in described groove;Described spiral layers silk is embedded into described groove In;The bottom coated with adhesive that described spiral layers silk is exposed from described groove;To be embedded with described in described spiral layers silk The inner side of described hollow tubular base material inserted by operation silk;And make the described bottom of described spiral layers silk and described hollow tubular base The inner surface bonding of material is firmly.
The present invention also provides another kind of method manufacturing the above-mentioned conduit coordinating seal wire to carry out Ink vessel transfusing push, described side Method includes:Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;Make spiral layers silk, described spiral layers The spiral external diameter being dimensioned such that described spiral layers silk of silk is less than or equal to the internal diameter of described hollow tubular base material;Will be described The inner side of described hollow tubular base material inserted by spiral layers silk;By heat effect, described hollow tubular base material is coated on described spiral shell On rotation layer silk, described spiral layers silk embeds the diameter less than described spiral layers silk for the depth of described hollow tubular base material.
Brief description
Fig. 1 (a) is the perspective view of the conduit carrying out Ink vessel transfusing push according to the cooperation seal wire of the present invention.
Fig. 1 (b), Fig. 1 (c), Fig. 1 (d) are the partial sectional views of this conduit, and generally curved, triangle, ladder are shown respectively The spiral layers section shape of shape.
Fig. 2 is the schematic diagram that calculated of maximum of the pitch to spiral layers.
Fig. 3 (a) is the fragmentary, perspective view of the rapid exchange balloon conduit after applying the present invention.
Fig. 3 (b), Fig. 3 (c), Fig. 3 (d) are the offices of the inner tube (i.e. the conduit of the present invention) of this rapid exchange balloon conduit Portion's sectional view, is shown respectively generally curved, triangle, trapezoidal spiral layers section shape.
Fig. 4 is the general illustration of this foley's tube.
Description of reference numerals
1 seal wire
2 conduits
3 spiral layers
4 guidewire port
5 far ultraviolet pipes
6 radiography sap cavities
7 Tip heads
R seal wire minimum bending radius
R seal wire radius
L pitch
Specific embodiment
Referring to Fig. 1,3,4, the conduit 2 according to the present invention is used as the inner tube of the conduit such as foley's tube or guiding catheter, and this is led Pipe 2 cooperation seal wire 1 carries out Ink vessel transfusing push, has spiral layers 3 in the inwall of this conduit 2.
Because the inwall of described conduit 2 has spiral layers 3, the contact between seal wire 1 and conduit 2 be discontinuous linear contact lay or Point contact, when pushing this conduit 2 along seal wire 1, while ensureing guide wire motion direction, greatly reduces seal wire 1 and conduit 2 Cooperation area, in conduit 2 progradation, reduces the frictional force of conduit 2 inwall and seal wire 1, and increase conduit 2 can pushability.
Meanwhile, the present invention change be conduit 2 inner cavity surface structure (towards the side of seal wire 1), with by change seal wire 1 Surface is compared come the method to reduce cooperation area and to reduce frictional force, by more difficult generation additional friction in propulsion.
Described spiral layers 3 can be distributed in the guidewire port end (i.e. one end close to guidewire port 4) of described conduit 2 to conduit Tip 7 (i.e. the other end farther out from guidewire port 4 of described conduit 2) between arbitrary region in.Preferably, described spiral Layer 3 distribution covers whole length of described conduits 2, so, even if there being the situation blocking seal wire 1 to occur, is also seal wire 1 in vitro Starting end rather than internal, will easily adjust.For example, in the rapid exchange balloon conduit shown in Fig. 3, because conduit 2 Length is shorter, in operation, install in vitro conduit 2 on the seal wire 1 after, seal wire 1 will pass from the guidewire port 4 of foley's tube, During pushing, smooth seal wire 1 will be always maintained at without there being change with the cooperation of conduit 2, will not conduit 2 be had additionally again Hinder and occur.
Referring to Fig. 1 (b), Fig. 1 (c), Fig. 1 (d) it is preferable that the surface court contacting with described seal wire 1 of described spiral layers 3 Raised to described seal wire 1, thus reducing the contact area of seal wire 1 and conduit 2 further.It is highly preferred that the court of described spiral layers 3 Section on the axial direction in described conduit 2 of the end raised to described seal wire 1 is curved or point-like, thus seal wire 1 with Contact between conduit 2 is point contact, further decreases the contact area of seal wire 1 and conduit 2.In described spiral layers 3 Towards the section on the axial direction in described conduit 2 of the end of described seal wire 1 projection curved in the case of, described spiral Layer 3 does not allow easy to wear coming off.
Width on the axial direction of described conduit 2 for the section of described spiral layers 3 is unrestricted, as long as this width ensures Be combined with pipe inner wall and be fixed well.It is, however, preferable that the section of described spiral layers 3 is in the axial direction of described conduit 2 On width taper into towards described seal wire 1.The possibility blocking seal wire 1 so can be reduced.It is highly preferred that described spiral layers 3 section shape is generally arc-shaped, triangle, trapezoidal or other polygon.Here described spiral shell is because using statement " substantially " The section shape of rotation layer 3 is not strict with as arc, triangle, trapezoidal or other polygon, such as in Fig. 1 (c), Fig. 1 (d) Shown triangle, the top of trapezoidal cross-sectional shape can be rounded as arc.
Preferably, the surface contacting with described seal wire 1 of described spiral layers 3 has the coating for reducing friction.More excellent Selection of land, described coating can include organosilicon;Described coating can include hydrophilic organics hydrophilicity or hydrophobic organic compound.More enter one Preferably, described hydrophobic organic compound coating includes politef (PTFE) or Parylene (PARYLENE) to step.
The height in the radial direction in described conduit 2 of described spiral layers 3 is unrestricted, but leads described in being preferably slightly smaller than The radius of silk 1.
Preferably, the maximum being referred to pitch L to spiral layers 3 for the Fig. 2 calculates.In order that being in maximum deflection The seal wire 1 of state still can stably guide conduit 2, and the seal wire 1 being in maximum deflection state preferably contacts described spiral layers 3 The top of two adjacent threads rather than only contact be located at described two adjacent threads between valley so that being in maximum Seal wire 1 and the conduit 2 of case of bending form stable three point contact, smoothly to guide conduit 2.Pitch L shown in Fig. 2 is Maximum pitch Lmax.
If the radius of seal wire 1 is r, the minimum bending radius of seal wire 1 (is in the bending of the seal wire 1 of maximum deflection state Radius) it is R, and the height in the radial direction in described conduit 2 of described spiral layers 3 is taken as r, then met according to Pythagorean theorem Following formula (1):
(Lmax/2) ^2+ (R+r) ^2=(R+2r) ^2 (1)
Formula (2) is derived from further according to formula (1):
Lmax=2*sqrt (3r^2+2R*r) (2)
In other words, pitch L of described spiral layers is selected according to below equation (3):
L<=2*sqrt (3r^2+2R*r) (3)
Preferably, described spiral layers 3 are made up of hard material.It is highly preferred that described hard material be macromolecular material or Metal material.It is further preferred that described hard material is engineering plastics or alloy.It is further preferred that described alloy is Rustless steel or Nitinol.It is further preferred that described engineering plastics are polyamide or polyester.
As described above, described spiral layers 3 are made up of hard material, its hardness is more than the hardness of conduit 2.It is therefore preferable that will Spiral layers 3 and catheter body are fabricated separately.
For example, the manufacture method of conduit 2 can include:Prepare hollow tubular base material, described hollow tubular base material is used as to lead Tube body;Make helical form operation silk, the spiral external diameter of described operation silk is matched with the internal diameter of described hollow tubular base material, institute The outside stating operation silk has groove, and described operation silk length in the axial direction is more than the length of described hollow tubular base material Degree;Make spiral layers silk, described spiral layers silk be dimensioned such that described spiral layers silk can be embedded in described groove In;Described spiral layers silk is embedded in described groove;The bottom that described spiral layers silk is exposed from described groove is coated viscous Mixture;The described operation silk being embedded with described spiral layers silk is inserted the inner side of described hollow tubular base material;And make described spiral shell The described bottom of rotation layer silk is bonded firmly with the inner surface of described hollow tubular base material.
Said method is by being adhered to, by described spiral layers silk, the conduit that described hollow tubular base material manufactures the present invention.But It is to the invention is not restricted to this construction.For example, it is also possible to by by described spiral layers silk be thermally bonded to described hollow tubular base material Lai Manufacture the conduit of the present invention.Another kind of manufacture method of conduit 2 can include:Prepare hollow tubular base material, described hollow tubular Base material is used as catheter body;Make spiral layers silk, the spiral being dimensioned such that described spiral layers silk of described spiral layers silk External diameter is less than or equal to the internal diameter of described hollow tubular base material;Described spiral layers silk is inserted the inner side of described hollow tubular base material; By heat effect, described hollow tubular base material is coated on described spiral layers silk, described spiral layers silk embeds described hollow pipe The depth of shape base material is less than the diameter of described spiral layers silk.
The conduit 2 of the present invention can be applied to the conduit that any cooperation seal wire carries out Ink vessel transfusing push.Below with reference to figure 3rd, the conduit of the 4 exemplary illustration present invention in the supravasal application of rapid exchange balloon it should be appreciated that following explanation simultaneously It is not intended to limit the invention to the inner tube of rapid exchange balloon conduit.
In the embodiment shown in fig. 3, the met minimum bending radius of rapid exchange balloon conduit is 9mm (model), institute It is 0.014 inch diameter or 0.178mm radius with seal wire, pitch L is calculated according to formula (3) and should be less than 3.633mm, take 3.6mm.
If make the inner tube 2 of this rapid exchange balloon conduit by bonding mode, concrete manufacturing process is as follows:
Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;
Make helical form operation silk, the spiral external diameter of described operation silk is matched with the internal diameter of described hollow tubular base material, The outside of described operation silk has groove, and groove pitch L is computed as described above and is taken as 3.6mm, and described operation silk is in axial side Length upwards is more than the length of described hollow tubular base material, that is, be more than 250mm or 70 circle screw thread;
Make spiral layers silk, described spiral layers silk to be dimensioned such that described spiral layers silk can be embedded in described In groove;
Described spiral layers silk is embedded in described groove;
The bottom coated with adhesive that described spiral layers silk is exposed from described groove;
The described operation silk being embedded with described spiral layers silk is inserted the inner side of described hollow tubular base material;And
The described bottom of described spiral layers silk is made to bond firmly with the inner surface of described hollow tubular base material.
If make the inner tube 2 of this rapid exchange balloon conduit by thermal mode, concrete manufacturing process is such as Under:
Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;
Make spiral layers silk, described spiral layers silk be dimensioned such that described spiral layers silk spiral external diameter be less than etc. In the internal diameter of described hollow tubular base material, pitch L of spiral layers silk is computed as described above and is taken as 3.6mm, and described spiral layers silk Length in the axial direction is more than the length of described hollow tubular base material, that is, be more than 250mm or 70 circle screw thread;
Described spiral layers silk is inserted the inner side of described hollow tubular base material;
By heat effect, described hollow tubular base material is coated on described spiral layers silk, described spiral layers silk embeds institute The depth stating hollow tubular base material is less than the diameter of described spiral layers silk.
In addition, the concrete practice for the different spiral layers section shape of three kinds as shown in Fig. 3 (b), Fig. 3 (c), Fig. 3 (d) As follows:
A. added form is hemispherical dome structure, and its cross sectional radius is 0.17mm, using polyamide material, and and hollow The inner surface good bond of tubular substrate.
B. added form is isosceles triangle, and triangle height takes 0.17mm, and bottom width is 0.34mm, summit warp Cross polishing, grind off wedge angle, curved, bond using stainless steel material and with the inner surface of hollow tubular base material.
C. added form is isosceles trapezoid, is highly equal to 0.17mm, and long base is 0.34mm, and short base takes 0.17mm, two jiaos of short base are removed in polishing, make short base be in middle high, and the low arc in both sides is made using polyamide material.Long Base is bonded in the inner surface of hollow tubular base material.
Apply the present invention in the making of rapid exchange balloon conduit, increase this with the inner tube wall that seal wire coordinates The spiral layers of bright advocated structure, while limiting guarantee conduit direction of advance, substantially reduce conduit and seal wire contact area, Reduce sliding-frictional resistance, thus reducing the frictional resistance in propulsion.

Claims (18)

1. a kind of cooperation seal wire carries out the conduit of Ink vessel transfusing push, wherein:The inwall of described conduit has spiral layers;Described spiral The hardness of layer is more than the hardness of described conduit;
It is characterized in that select pitch L of described spiral layers according to below equation:
L<=2*sqrt (3r^2+2R*r)
Wherein r is seal wire radius, and R is the minimum bending radius of described seal wire, and the radial direction in described conduit of described spiral layers Height on direction is taken as r.
2. according to claim 1 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described spiral layers are divided Cloth is in the arbitrary region between the two ends of described conduit.
3. according to claim 2 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described spiral layers are divided Cloth covers whole length of described conduit.
4. according to claim 1 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described spiral layers with The surface of described seal wire contact is towards described seal wire projection.
5. according to any one of claim 1 to 4 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that: Width on the axial direction of described conduit for the section of described spiral layers tapers into towards described seal wire.
6. according to claim 5 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described spiral layers Section shape is generally arc-shaped, triangle, trapezoidal or other polygon.
7. according to any one of claim 1 to 4 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that: The surface that described spiral layers are contacted with described seal wire has the coating for reducing friction.
8. according to claim 7 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described coating includes Organosilicon.
9. according to claim 7 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described coating includes Hydrophilic organics hydrophilicity or hydrophobic organic compound.
10. according to claim 9 cooperation seal wire carry out Ink vessel transfusing push conduit it is characterised in that:Described hydrophobicity Organic substance includes politef or Parylene.
11. according to any one of claim 1 to 4 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that: The height in the radial direction in described conduit of described spiral layers is less than the radius of described seal wire.
12. according to any one of claim 1 to 4 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that: Described spiral layers are made up of hard material.
13. according to claim 12 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that:Described hard material Material is macromolecular material or metal material.
14. according to claim 13 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that:Described hard material Material is engineering plastics or alloy.
15. according to claim 14 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that:Described alloy is Rustless steel or Nitinol.
16. according to claim 14 cooperation seal wires carry out Ink vessel transfusing push conduits it is characterised in that:Described engineering plastic Material is polyamide or polyester.
A kind of 17. cooperation seal wires manufacturing according to any one of claim 1 to 16 carry out the side that Ink vessel transfusing pushes conduit Method, methods described includes:
Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;
Make helical form operation silk, the spiral external diameter of described operation silk is matched with the internal diameter of described hollow tubular base material, described The outside of operation silk has groove, and described operation silk length in the axial direction is more than the length of described hollow tubular base material Degree;
Make spiral layers silk, described spiral layers silk be dimensioned such that described spiral layers silk can be embedded in described groove In;
Described spiral layers silk is embedded in described groove;
The bottom coated with adhesive that described spiral layers silk is exposed from described groove;
The described operation silk being embedded with described spiral layers silk is inserted the inner side of described hollow tubular base material;And
The described bottom of described spiral layers silk is made to bond firmly with the inner surface of described hollow tubular base material.
A kind of 18. cooperation seal wires manufacturing according to any one of claim 1 to 16 carry out the conduit of Ink vessel transfusing push Method, methods described includes:
Prepare hollow tubular base material, described hollow tubular base material is used as catheter body;
Make spiral layers silk, the spiral external diameter being dimensioned such that described spiral layers silk of described spiral layers silk is less than or equal to institute State the internal diameter of hollow tubular base material;
Described spiral layers silk is inserted the inner side of described hollow tubular base material;
By heat effect, described hollow tubular base material is coated on described spiral layers silk, described spiral layers silk embed described in The depth of empty tubular substrate is less than the diameter of described spiral layers silk.
CN201210393570.2A 2012-10-16 2012-10-16 Catheter pushed into blood vessel in cooperation with guide wire and manufacturing method thereof Active CN103721337B (en)

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Application Number Priority Date Filing Date Title
CN201210393570.2A CN103721337B (en) 2012-10-16 2012-10-16 Catheter pushed into blood vessel in cooperation with guide wire and manufacturing method thereof
PCT/CN2013/085274 WO2014059922A1 (en) 2012-10-16 2013-10-16 Catheter coupling with guide wire for intravascular delivery and manufacturing method thereof

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CN201210393570.2A CN103721337B (en) 2012-10-16 2012-10-16 Catheter pushed into blood vessel in cooperation with guide wire and manufacturing method thereof

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CN103721337A CN103721337A (en) 2014-04-16
CN103721337B true CN103721337B (en) 2017-02-22

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JP6344762B2 (en) * 2014-05-21 2018-06-20 朝日インテック株式会社 catheter
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