CN103721003A - 一种治疗肾精不足型小儿脑积水的中药制剂 - Google Patents
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Abstract
本发明公开了一种治疗肾精不足型小儿脑积水的中药制剂。小儿脑积水属于中医学“解颅”、“囟填”的范畴，本病由先天禀赋不足，当肾精不充，则难以主骨生髓，脑失髓养，髓海空虚而易致水邪内积于脑，囟门开解。本发明选择补肾益髓、通窍利水的中药长筒马先蒿、巴戟天、鹿药、菟丝子、豇豆、香石藤果、磨盘根、三块瓦、苋，水煎成汤剂，经临床试验，总有效率96.7％，疗效非常显著。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗肾精不足型小儿脑积水的中药制剂。
背景技术
小儿脑积水是儿科常见的疑难病之一，是一种以颅内脑脊液存量增多，脑室***或(和)蛛网膜下腔扩大为主要特征的病症。小儿脑积水是儿科疑难症之一，西医治疗该病采用手术和西药等多种方法，手术方法多种多样，但是存在诸多的问题，如手术失败率相对较高，手术后感染相对较多，随着年龄的增长，体格的发育，需要多次手术，患者需要承受多次痛苦。西药治疗主要以脱水利尿，抑制脑积液的分泌，但副作用很大。中医药治疗本病具有独特的优势，中医认为本病证候存在着实证，如瘀、痰、湿、风邪等，也并不是单一的脏腑病变，常见脾、肾、肝、脑连合受累，总体上呈本虚标实，虚实夹杂之候，在疾病的发展过程中本病的证候具有时空效应或动态演变的特性。因此中医治疗该病分清病机、辩证施治，疗效显著。同时中医治疗副作用小，操作简单，婴幼儿患者依附性较强，取得了较好的临床疗效。
发明内容
本发明的目的是提供一种治疗肾精不足型小儿脑积水的中药制剂。小儿脑积水属于中医学“解颅”、“囟填”的范畴，本病由先天禀赋不足，当肾精不充，则难以主骨生髓，脑失髓养，髓海空虚而易致水邪内积于脑，囟门开解。针对肾精不足型小儿脑积水的病机，本发明采取补肾益髓、通窍利水的治法。
本发明的目的是通过以下技术方案实现的，该治疗肾精不足型小儿脑积水的中药制剂由以下重量份的中药制成：长筒马先蒿6-9份、巴戟天5-7份、鹿药10-14份、菟丝子9-15份、豇豆20-30份、香石藤果6-9份、磨盘根9-15份、三块瓦3-9份、苋10-20份。
优选的，长筒马先蒿7份、巴戟天6份、鹿药12份、菟丝子12份、豇豆25份、香石藤果7份、磨盘根12份、三块瓦6份、苋15份。
制备方法 将上述中药水煎制成汤剂。
方中：长筒马先蒿利水、涩精；巴戟天补肾阳、壮筋骨、祛风湿；鹿药壮阳益肾、活血调经、祛风除湿；菟丝子补肝肾、益精髓；豇豆健脾益气、补肾利水；香石藤果益精固肾；磨盘根清热利湿、通淋、活血、开窍；三块瓦清热利水、散瘀消肿；苋清热利尿开窍；
临床资料
1、一般资料 在30例患者中，男21例，女9例；年龄5个月～3岁，其中5个月～1岁23例，1～2岁5例，2～3岁2例。
2、诊断标准 西医诊断标准：(1)头围超过国内标准2个标准差；(2)囟门扩大，逾期不闭，紧张饱满或颅缝开裂；(3)眼球下旋如落日状，或震颤，或斜视；(4)智力低下；(5)语言迟缓，或运动发育异常，呕吐，抽搐，而难以用其他疾病解释者；(6)影像学(CT、MRI、脑室造影)检查证实有脑积水者。
中医辨证症候：多愁少喜，头发稀少，头颅大，囟门逾期不合，牙齿逾期不出，神识呆钝，发育迟缓，舌淡苔薄白，脉细弱，指纹淡青。
3、治疗方法 患者服用本发明所述的中药制剂，称取长筒马先蒿7g、巴戟天6g、鹿药12g、菟丝子12g、豇豆25g、香石藤果7g、磨盘根12g、三块瓦6g、苋15g。水煎成汤剂，每日一剂，分早晚2次服用。30天为一疗程，连续治疗3个疗程。
4、疗效标准 痊愈：CT复查正常，临床症状消失，体格检查无异常；好转：复查头颅CT脑积水部分吸收，临床症状好转；无效：复查头颅CT脑积水无改善，临床症状无好转。
5、治疗结果 治疗3个疗程后观察疗效，其中痊愈18例(60％)，好转11例(36.7％)，无效1例(3.3％)，总有效率96.7％；
具体实施方式
实施例一：称取长筒马先蒿7g、巴戟天6g、鹿药12g、菟丝子12g、豇豆25g、香石藤果7g、磨盘根12g、三块瓦6g、苋15g，将上述中药水煎成汤剂。
实施例二：称取长筒马先蒿9g、巴戟天5g、鹿药14g、菟丝子9g、豇豆30g、香石藤果6g、磨盘根15g、三块瓦3g、苋20g，将上述中药水煎成汤剂。
实施例三：称取长筒马先蒿6g、巴戟天7g、鹿药10g、菟丝子15g、豇豆20g、香石藤果9g、磨盘根9g、三块瓦9g、苋10g，将上述中药水煎成汤剂。
Claims (2)
1.一种治疗肾精不足型小儿脑积水的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：长筒马先蒿6-9份、巴戟天5-7份、鹿药10-14份、菟丝子9-15份、豇豆20-30份、香石藤果6-9份、磨盘根9-15份、三块瓦3-9份、苋10-20份。
2.根据权利要求1所述的一种治疗肾精不足型小儿脑积水的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：长筒马先蒿7份、巴戟天6份、鹿药12份、菟丝子12份、豇豆25份、香石藤果7份、磨盘根12份、三块瓦6份、苋15份。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352888A (zh) * | 2014-10-24 | 2015-02-18 | 王刚 | 一种治疗小儿脑积水的内服外用中药组合物 |
| CN104922529A (zh) * | 2015-07-15 | 2015-09-23 | 孙云香 | 一种治疗脑积水的中药组合物 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1255337A (zh) * | 1998-11-27 | 2000-06-07 | 宋虎杰 | 治疗脑积水的药物 |
| CN1634385A (zh) * | 2004-11-04 | 2005-07-06 | 谢静 | 治疗脑积水、脑水肿和颅内压增高的中药组合物 |
| CN101559152A (zh) * | 2009-05-19 | 2009-10-21 | 李桂华 | 一种治疗脑积水的中药制剂及其制备方法 |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1255337A (zh) * | 1998-11-27 | 2000-06-07 | 宋虎杰 | 治疗脑积水的药物 |
| CN1634385A (zh) * | 2004-11-04 | 2005-07-06 | 谢静 | 治疗脑积水、脑水肿和颅内压增高的中药组合物 |
| CN101559152A (zh) * | 2009-05-19 | 2009-10-21 | 李桂华 | 一种治疗脑积水的中药制剂及其制备方法 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352888A (zh) * | 2014-10-24 | 2015-02-18 | 王刚 | 一种治疗小儿脑积水的内服外用中药组合物 |
| CN104922529A (zh) * | 2015-07-15 | 2015-09-23 | 孙云香 | 一种治疗脑积水的中药组合物 |
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