CN103705889A - Traditional Chinese medicine preparation for treating chronic bronchitis - Google Patents

Traditional Chinese medicine preparation for treating chronic bronchitis Download PDF

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Publication number
CN103705889A
CN103705889A CN201310730569.9A CN201310730569A CN103705889A CN 103705889 A CN103705889 A CN 103705889A CN 201310730569 A CN201310730569 A CN 201310730569A CN 103705889 A CN103705889 A CN 103705889A
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parts
chinese medicine
radix
chronic bronchitis
medicine preparation
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CN201310730569.9A
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许伟
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic bronchitis. The traditional Chinese medicine preparation is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 15-30 parts of pinellia ternate, 20-30 parts of mangnolia officinalis, 20-40 parts of poria, 5-15 parts of perilla leaf, 5-15 parts of ginger, 10-20 parts of radix bupleuri, 15-35 parts of rhizoma cyperi, 15-30 parts of fructus aurantii, 15-30 parts of white paeony root, 5-15 parts of liquorice, 10-20 parts of radix clematidis and 10-20 parts of platycodon grandiflorum. The medicines have compatibility, the pharmacological synergy has an obvious treatment effect of treating the chronic bronchitis, the relapse rate of the healed chronic bronchitis is low, and the traditional Chinese medicine preparation has small toxic and side effects.

Description

A kind of Chinese medicine preparation for the treatment of chronic bronchitis
Technical field:
The present invention relates to technical field of Chinese medicines, specifically a kind of Chinese medicine preparation for the treatment of chronic bronchitis.
Background technology:
Chronic bronchitis is to be changed and formed by acute bronchitis.Primary disease mostly occurs at middle age age group, and the course of disease is slow, and most hidden latent onsets, from the beginning of falling ill in cold season.The symptom that occurs cough and expectoration, outstanding early morning is the most obvious, the expectorant mucus spume shape that is white in color, thickness is difficult for bringing up, infect or catch cold after symptom aggravate rapidly, amount of expectoration increases, viscosity increases or is yellow purulence.Sometimes in expectoration, can be with blood, along with PD, all have all the year round cough, expectoration, and take the autumn and winter as acute.The shortcomings such as doctor trained in Western medicine mostly adopts and contains antibiotic medicine the treatment of chronic bronchitis, but exists drug withdrawal easily repeatedly, and toxic and side effects is large, and the problem such as that how existing Chinese traditional patent formulation also exists therapeutic effect is not good, and the course for the treatment of is long.
Summary of the invention:
The present invention is exactly in order to overcome deficiency of the prior art, and disclosing a kind for the treatment of for chronic bronchitis, to have therapeutic effect obvious, controls recurrence rate after healing low, and the little Chinese medicine preparation of toxic and side effects.
The invention provides following technical scheme:
Treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Rhizoma Pinelliae 15-30 part, Cortex Magnoliae Officinalis 20-30 part, Poria 20-40 part, Folium Perillae 5-15 part, Rhizoma Zingiberis Recens 5-15 part, Radix Bupleuri 10-20 part, Rhizoma Cyperi 15-35 part, Fructus Aurantii 15-30 part, Radix Paeoniae Alba 15-30 part, Radix Glycyrrhizae 5-15 part, Radix Clematidis 10-20 part, Radix Platycodonis 10-20 part.
Preferred weight umber is:
20 parts of the Rhizoma Pinelliaes, 15 parts of Cortex Magnoliae Officinalis, 30 parts of Poria, 10 parts of Folium Perillae, 10 parts, Rhizoma Zingiberis Recens, 12 parts of Radix Bupleuri, 20 parts of Rhizoma Cyperis, 20 parts of Fructus Aurantiis, 20 parts of the Radix Paeoniae Albas, 10 parts, Radix Glycyrrhizae, 15 parts of Radix Clematidis, 15 parts of Radix Platycodoniss.
A Chinese medicine preparation for the treatment of chronic bronchitis, is characterized in that: can adopt the preparation method of Chinese medicine to make decoction, powder and tablet.
The present invention's herbal nature used is as follows:
The Rhizoma Pinelliae: acrid in the mouth, warm in nature.Return lung, spleen, stomach warp.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, the effects such as reducing swelling and alleviating pain.This product also has the effects such as antiulcer, blood fat reducing, tranquilizing soporific, antitumor, removing toxic substances antiinflammatory.
Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature.Return spleen, stomach, large intestine channel.Have circulation of qi promoting removing food stagnancy, dampness is removed full, the effects such as lowering the adverse QI to relieve asthma.The decoct of this product has broad-spectrum antibacterial action.Also there is the coacervation of the platelet of inhibition, the effects such as blood pressure lowering.
Medulla Tetrapanacis: sweet in the mouth, light, cold nature.Return lung, stomach, urinary bladder channel.There is the effects such as inducing diuresis for treating stranguria syndrome.
Poria: sweet in the mouth, light, property are flat.GUIXIN, spleen kidney channel.There is promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, the effect such as relieve internal heat anticancer.This product is for cough due to fluid-retention, and phlegm-damp enters network, and aching pain in should and back Poria can promoting diuresis to eliminate damp pathogen, has again a function of invigorating spleen, for insufficiency of the spleen can not transmitting and distributing the fluids, stop the disease of the raw phlegm retention of dimerization, there is therapeutical effect.
Folium Perillae: acrid in the mouth, slightly warm in nature.Return spleen, lung meridian.There is expelling cold and relieving exterior syndrome, lung qi dispersing cough-relieving, the effects such as regulating the flow of Qi and the middle Jiao.
Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature.Return lung, spleen channel.There is relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, the effect of warming the lung to relieve cough.Research shows: this product has gone out to have, antiinflammatory, protect the liver, outside the effect such as function of gallbladder promoting, antioxidation, its contained shogaol also has excited vasomotor center, respiratory center and action of the heart.
Radix Bupleuri: bitter in the mouth, pungent, cold nature.Return Liver Channel, gallbladder meridian.There is expelling pathogenic factors from the exterior and expel the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, the effects such as elevate a turnable ladder yang-energy.In this product contained Bupleurum chinense polysaccharide can improve cell phagocytic function, Natural killer activity is strengthened, improve special viral antibody titre, improve lymphocyte and turn core rate, improve skin delayed hypersensitivity reaction.Use injection of Radix Bupleuri (concentration 1: 1) 1 ml/ to carry out subcutaneous injection to rat, within continuous 5 days, can significantly reduce the rat blood serum GPT rising that carbon tetrachloride causes, hepatocellular degeneration and necrosis also obviously alleviate, and in hepatocyte, glycogen and rna content also approach normal.
Rhizoma Cyperi: acrid in the mouth, sweet, slightly warm in nature.Return liver, tri-jiao channel.There is the resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; The effect such as antiabortive.The ethanol extract of this product has antiinflammatory, analgesia, the effect such as antipyretic; The water decoction of this product can promote the effect of bile secretion.
Fructus Aurantii: bitter in the mouth, acid, cold nature.Return lung, spleen, liver, stomach, large intestine channel.There is spleen benefiting and stimulating the appetite, adjust the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, preventing or arresting vomiting is contrary, the effect of expectorant.This product has the coronary flow of increasing and kidney blood flow blood, has the very strong effect of bringing out the myocardium rhythm and pace of moving things, and its intensity and epinephrine are suitable, and stronger than dopamine and Neosynephrine.In Fructus Aurantii, contained Neosynephrine is epinephrine a-receptor agonist, and heart B-receptor is also had to certain excitation.There is vasoconstrictive, produce the hypertensive effect that rises.
The Radix Paeoniae Alba: bitter in the mouth, acid, sweet, cold nature.Return liver, spleen channel.There is nourishing blood for regulating menstruation, suppressing the hyperactive liver pain relieving, the effects such as astringing YIN to stop sweating.In this product, contained paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose, the effect such as protects the liver.
Radix Glycyrrhizae: sweet in the mouth, property is flat.Enter spleen, stomach, lung meridian.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.This product also has antiinflammatory, antiviral, and protecting liver and detoxication and strengthen the functions such as immunity, anti-cancer and cancer-preventing, interferon inducer and cell immunomodulator.
Radix Clematidis: acrid in the mouth, salty, warm in nature.Return urinary bladder channel.There is wind-damp dispelling, the meridian dredging, the effects such as expectorant water.Research shows: this product also has the effects such as analgesia, function of gallbladder promoting, and decoct has obvious antibiotic effect, and Grain-positive and negative bacterium, mycete are all had to stronger inhibitory action.
Radix Platycodonis: bitter in the mouth, pungent, property is flat.Lung meridian.There is lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, the effect such as foster the spirit of nobility.Radix Platycodonis decoct is given anesthesia Canis familiaris L. gavage with 1 g/kg, can make respiratory tract secretion increase; Kikyosaponin crude product has calmness, analgesia and the central inhibitory action such as antipyretic, and has antiinflammatory and relieving cough and expelling phlegm, blood vessel dilating, blood pressure lowering, antiulcer action; Radix Platycodonis methanolic extract and thick Saponin gavage, and can strengthen mice carbon clearance speed. and Radix Platycodonis skin also has phlegm-dispelling functions. and kikyosaponin has haemolysis.
The invention has the advantages that, all medicine compatibilities, pharmacology is collaborative, and for treatment chronic bronchitis, to have therapeutic effect obvious, controls recurrence rate after healing low, and the advantage such as toxic and side effects is little.
The specific embodiment:
Below in conjunction with embodiment and clinical data, be described further.
Embodiment 1:
Treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 15 parts of the Rhizoma Pinelliaes, 15 parts of Cortex Magnoliae Officinalis, 30 parts of Poria, 8 parts of Folium Perillae, 10 parts, Rhizoma Zingiberis Recens, 10 parts of Radix Bupleuri, 15 parts of Rhizoma Cyperis, 15 parts of Fructus Aurantiis, 15 parts of the Radix Paeoniae Albas, 10 parts, Radix Glycyrrhizae, 15 parts of Radix Clematidis, 15 parts of Radix Platycodoniss.
Embodiment 2:
Treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 20 parts of the Rhizoma Pinelliaes, 15 parts of Cortex Magnoliae Officinalis, 30 parts of Poria, 10 parts of Folium Perillae, 10 parts, Rhizoma Zingiberis Recens, 12 parts of Radix Bupleuri, 20 parts of Rhizoma Cyperis, 20 parts of Fructus Aurantiis, 20 parts of the Radix Paeoniae Albas, 10 parts, Radix Glycyrrhizae, 15 parts of Radix Clematidis, 15 parts of Radix Platycodoniss.
Embodiment 3:
Treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 25 parts of the Rhizoma Pinelliaes, 25 parts of Cortex Magnoliae Officinalis, 35 parts of Poria, 13 parts of Folium Perillae, 12 parts, Rhizoma Zingiberis Recens, 18 parts of Radix Bupleuri, 26 parts of Rhizoma Cyperis, 25 parts of Fructus Aurantiis, 22 parts of the Radix Paeoniae Albas, 13 parts, Radix Glycyrrhizae, 12 parts of Radix Clematidis, 16 parts of Radix Platycodoniss.
 
Use the present invention to treat 127 routine chronic tracheitis patients, male's 78 examples wherein, women's 49 examples, the half a year that the course of disease is the shortest, the longest 8 years.
Therapeutic Method: take the present invention every day: decoction potion is taken once sooner or later one week is a course for the treatment of; Powder or tablet be every day 3 each 10G within mono-week, be a course for the treatment of.
Treatment standard:
Cure: nothing recurrence in continuous 1 year or seldom recurrence after curing.Effective: disease symptom has clear improvement, the morbidity persistent period obviously shortens.Effective: disease symptom has clear improvement, the morbidity persistent period reduces to some extent.Invalid: disease symptom is front without any improvement with treatment.
Therapeutic effect:
Take 2-3 of the present invention after the course for the treatment of, cure 21 examples and account for 16.53% of total number of persons; Effective 100 examples account for 78.74% of total number of persons; Invalid 6 examples account for 4.72% of total number of persons.Total effective rate of the present invention is 95.27%.

Claims (3)

1. treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Rhizoma Pinelliae 15-30 part, Cortex Magnoliae Officinalis 20-30 part, Poria 20-40 part, Folium Perillae 5-15 part, Rhizoma Zingiberis Recens 5-15 part, Radix Bupleuri 10-20 part, Rhizoma Cyperi 15-35 part, Fructus Aurantii 15-30 part, Radix Paeoniae Alba 15-30 part, Radix Glycyrrhizae 5-15 part, Radix Clematidis 10-20 part, Radix Platycodonis 10-20 part.
2. according to a kind of Chinese medicine preparation for the treatment of chronic bronchitis described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 20 parts of the Rhizoma Pinelliaes, 15 parts of Cortex Magnoliae Officinalis, 30 parts of Poria, 10 parts of Folium Perillae, 10 parts, Rhizoma Zingiberis Recens, 12 parts of Radix Bupleuri, 20 parts of Rhizoma Cyperis, 20 parts of Fructus Aurantiis, 20 parts of the Radix Paeoniae Albas, 10 parts, Radix Glycyrrhizae, 15 parts of Radix Clematidis, 15 parts of Radix Platycodoniss.
3. according to a kind of Chinese medicine preparation for the treatment of chronic bronchitis described in claim 1 or 2, it is characterized in that: can adopt the preparation method of Chinese medicine to make decoction, powder and tablet.
CN201310730569.9A 2013-12-27 2013-12-27 Traditional Chinese medicine preparation for treating chronic bronchitis Pending CN103705889A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103736057A (en) * 2014-01-02 2014-04-23 许伟 Traditional Chinese medicinal preparation for treating chronic bronchitis
CN107496756A (en) * 2017-07-27 2017-12-22 刘道鹏 It is a kind of to be used to treat electuary of chronic bronchitis and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1368265A (en) * 2001-02-06 2002-09-11 杨孟君 Nano medicine 'Xingsu' and its preparing process
CN102824624A (en) * 2012-08-31 2012-12-19 王效良 Traditional Chinese medicine for treating bronchitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1368265A (en) * 2001-02-06 2002-09-11 杨孟君 Nano medicine 'Xingsu' and its preparing process
CN102824624A (en) * 2012-08-31 2012-12-19 王效良 Traditional Chinese medicine for treating bronchitis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
周楚雄等: ""半夏厚朴汤临床应用6例"", 《咸宁学院学报(医学版)》, vol. 22, no. 1, 31 December 2008 (2008-12-31) *
王振江等主编: "《老年病与延年益寿》", 28 February 2007, article ""老年病与延年益寿"" *
马馨等: "《中国传统医学宝典》", 30 September 2004, article ""中国传统医学宝典"" *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103736057A (en) * 2014-01-02 2014-04-23 许伟 Traditional Chinese medicinal preparation for treating chronic bronchitis
CN107496756A (en) * 2017-07-27 2017-12-22 刘道鹏 It is a kind of to be used to treat electuary of chronic bronchitis and preparation method thereof

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Application publication date: 20140409

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