CN103655948A - Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof - Google Patents
Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof Download PDFInfo
- Publication number
- CN103655948A CN103655948A CN201310576045.9A CN201310576045A CN103655948A CN 103655948 A CN103655948 A CN 103655948A CN 201310576045 A CN201310576045 A CN 201310576045A CN 103655948 A CN103655948 A CN 103655948A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- raw material
- chinese medicine
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of traditional Chinese veterinary medicines, and in particular relates to traditional Chinese veterinary medicine injection for treating cow mastitis and a preparation method thereof. The traditional Chinese veterinary medicine injection is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 20-40 parts of cordate houttuynia, 10-30 parts of Chinese violet, 20-50 parts of dandelion and 10-30 parts of motherwort. The traditional Chinese veterinary medicine disclosed by the invention has functions of resisting bacteria and relieving swelling, and has good effect on treating cow mastitis.
Description
technical field
The invention belongs to herbal medicine technical field, be specifically related to a kind of herbal medicine injection for the treatment of mammitis of cow and preparation method thereof.
background technology
Mammitis of cow is the inflammation of breast interstitial, essence or interstitial parenchymal tissue, it is characterized in that milk degeneration, breast tissue present swelling, warm and pain to some extent.The cause of disease is many by due to mechanical irritation, pathogenic microorganism immersion or the damage of chemicals rationality, is mainly divided into serosity mastitis, fiber disposition mucositis mastitis, suppurative mastitis, hemorrhagic mastitis, gangrenous mastitis and latent mammitis.
The method often adopting in the process for the treatment of at present has penicillin intramuscular injection or quiet note, also can in breast, direct administration inject mycillin, but these modes all adopts the mode of Western medicine, easily produce drug resistance.
Chinese crude drug is the national treasure of China, and along with scientific and technical development, Chinese veterinarian and herbal medicine are also progressively mentioned country in the works, and Chinese medicine is approved by numerous raisers gradually because of the advantage of its high effect nontoxic, noresidue.Herbal medicine clinical practice is extensive, and therapeutic effect is good, easily absorbs, and noresidue, has no side effect, and is approved gradually, but traditional handicraft remains unchanged, alcohol precipitating method extracts, complex process, and complex operation, energy consumption is large.Finding a kind of Chinese medicine preparation that is applicable to treat mammitis of cow is a current research direction.
summary of the invention
The object of the present invention is to provide a kind of herbal medicine injection for the treatment of mammitis of cow and preparation method thereof.
The present invention is by the following technical solutions:
Treat a herbal medicine injection for mammitis of cow, by the raw material of Chinese medicine of following weight portion, be prepared from: 20～40 parts of Herba Houttuyniae, 10～30 parts of Herba Violaes, 20～50 parts of Herba Taraxacis, 10～30 parts of Herba Leonuris.
The method of preparing herbal medicine injection, comprises the following steps: 1) get in proportion each raw material of Chinese medicine; 2) above raw material of Chinese medicine is mixed, by the water boiling and extraction of five times of raw material of Chinese medicine gross weights 2-3 time, merge extractive liquid,, filters, and filtrate merging is concentrated into the gross weight of former raw material of Chinese medicine, adds the flocculating agent 2-3 days that flocculates; 3) get the supernatant after flocculation, filter embedding, sterilizing.
Described flocculating agent is ZTC1+1 II natural clarifying agent, and the addition of flocculating agent is for the 5-15% of filtrate quality after concentrated, with 8% best results.
In raw material of Chinese medicine of the present invention, Herba Houttuyniae, heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome; Herba Violae, heat-clearing and toxic substances removing, removing heat from blood detumescence; Herba Taraxaci, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation; Herba Leonuri, invigorates blood circulation, the silt of dispelling, and regulating menstruation, water disappears.The present invention, by above four kinds of Chinese medicine reasonable compatibilities, complements each other, and plays altogether the effect of detumescence, hemostasis and anti-inflammation, mammitis of cow is played to the effect for the treatment of both the principal and secondary aspects of a disease.
That the present invention has is antibacterial, the effect of detumescence, and mammitis of cow is had to good curative effect, effective percentage 100%, and cure rate can reach more than 90%, and noresidue, has no side effect, and pregnant domestic animal and lactation period all can be used, and can not remain in milk human body is damaged.
Preparation technology of the present invention is simple, and production cost is low, and properties of product are stable, can large-scale industrial production.
the specific embodiment
Embodiment 1
The herbal medicine injection for the treatment of mammitis of cow, is prepared from by the raw material of Chinese medicine of following weight portion: Herba Houttuyniae 40g, Herba Violae 10g, Herba Taraxaci 20g, Herba Leonuri 25g.
During preparation, comprise the following steps: 1) by measuring each raw material of Chinese medicine; 2) above raw material of Chinese medicine is mixed, use respectively 475g water boiling and extraction 2 times, merge extractive liquid,, filters, and filtrate merging is concentrated into 95g, adds ZTC1+1 II natural clarifying agent flocculation 2 days; 3) get the supernatant after flocculation, filter embedding, sterilizing.
Embodiment 2
The herbal medicine injection for the treatment of mammitis of cow, is prepared from by the raw material of Chinese medicine of following weight portion: Herba Houttuyniae 30g, Herba Violae 15g, Herba Taraxaci 30g, Herba Leonuri 30g.
During preparation, comprise the following steps: 1) by measuring each raw material of Chinese medicine; 2) above raw material of Chinese medicine is mixed, use respectively 525g water boiling and extraction 2 times, merge extractive liquid,, filters, and filtrate merging is concentrated into 105g, adds ZTC1+1 II natural clarifying agent flocculation 2 days; 3) get the supernatant after flocculation, filter embedding, sterilizing.
Embodiment 3
The herbal medicine injection for the treatment of mammitis of cow, is prepared from by the raw material of Chinese medicine of following weight portion: Herba Houttuyniae 20g, Herba Violae 30g, Herba Taraxaci 50g, Herba Leonuri 10g.
During preparation, comprise the following steps: 1) by measuring each raw material of Chinese medicine; 2) above raw material of Chinese medicine is mixed, use respectively 550g water boiling and extraction 3 times, merge extractive liquid,, filters, and filtrate merging is concentrated into 110g, adds ZTC1+1 II natural clarifying agent flocculation 3 days; 3) get the supernatant after flocculation, filter embedding, sterilizing.
application test
test material
Select 50 of milch cows as subjects, mastitis disease symptom is that milk degeneration, breast tissue present swelling, warm and pain to some extent.Medicine used is: the embodiment of the present invention 2 products, injection benzylpenicillin potassium.
test method
Test milch cow is divided into 5 groups at random, every group 10, be respectively dosage group (every cow head intramuscular injection 10ml embodiment 2 product administrations) in low dose group of the present invention (every cow head intramuscular injection 5ml embodiment 2 product administrations), the present invention, high dose group of the present invention (every cow head intramuscular injection 15ml embodiment 2 product administrations), injection benzylpenicillin potassium group (every cow head intramuscular injection 5g administration), blank group (need not any medicine).
The symptom of each group of record before test, the same time is used in conjunction 2 days according to the scheme of setting intramuscular administration, once a day; After drug withdrawal, symptom that record is respectively organized respectively, continuous 2 days, the evaluation effect while asking its cure rate as off-test, compared the symptom cure rate of each test group test.Criterion of cure: milk is normal, swelling, warm, pain symptom disappearance; Effective standard: milk improves, swelling, warm, pain symptom partly disappear; Invalid standard: milk is without improvement, swelling, warm, pain symptom are without improvement.
Cure rate=healing milk ox head number/this group milk ox head number
Effective percentage=(curing milk ox head number+effective milk ox head number)/this group milk ox head number
result of the test
Before and after test, the cure rate of each group is as shown in table 1.
The cure rate of each group before and after table 1 test
| Group | Milk ox head number | Cure a number | Effective number | Invalid number | Cure rate/% | Effective percentage/% |
| Low dose group of the present invention | 10 | 6 | 4 | 0 | 60 | 100 |
| Dosage group in the present invention | 10 | 9 | 1 | 0 | 90 | 100 |
| High dose group of the present invention | 10 | 10 | 0 | 0 | 100 | 100 |
| Injection benzylpenicillin potassium group | 10 | 10 | 0 | 0 | 100 | 100 |
| Blank group | 10 | 0 | 0 | 10 | 0 | 0 |
As can be seen from Table 1, herbal medicine injection effective percentage 100% of the present invention, the cure rate of low dosage of the present invention reaches 60%, the cure rate of the middle and high dosage of the present invention reaches more than 90%, particularly the therapeutic effect of high dose group of the present invention and injection benzylpenicillin potassium group is suitable, illustrates that the herbal medicine injection of this invention can be used as treatment mammitis of cow medicine.
Claims (3)
1. a herbal medicine injection for the treatment of mammitis of cow, is characterized in that, is prepared from: 20～40 parts of Herba Houttuyniae, 10～30 parts of Herba Violaes, 20～50 parts of Herba Taraxacis, 10～30 parts of Herba Leonuris by the raw material of Chinese medicine of following weight portion.
2. the method for preparation herbal medicine injection claimed in claim 1, is characterized in that, comprises the following steps: 1) get in proportion each raw material of Chinese medicine; 2) above raw material of Chinese medicine is mixed, use water boiling and extraction 2-3 time, merge extractive liquid,, filters, and filtrate merging is concentrated into the gross weight of former raw material of Chinese medicine, adds flocculating agent flocculation 2-3 days; 3) get the supernatant after flocculation, filter embedding, sterilizing.
3. the preparation method of herbal medicine injection as claimed in claim 2, is characterized in that, described flocculating agent is ZTC1+1 II natural clarifying agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310576045.9A CN103655948A (en) | 2013-11-18 | 2013-11-18 | Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310576045.9A CN103655948A (en) | 2013-11-18 | 2013-11-18 | Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103655948A true CN103655948A (en) | 2014-03-26 |
Family
ID=50295507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310576045.9A Pending CN103655948A (en) | 2013-11-18 | 2013-11-18 | Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103655948A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367715A (en) * | 2014-12-03 | 2015-02-25 | 徐自升 | Pure Chinese medicine compound for prevention and treatment of mastitis of dairy cows and preparation method thereof |
| CN104758432A (en) * | 2014-12-10 | 2015-07-08 | 北京康华远景科技股份有限公司 | Botanical drug preparation for treating mastitis of dairy cow and preparation method thereof |
| CN106344724A (en) * | 2016-10-27 | 2017-01-25 | 成都乾坤动物药业股份有限公司 | Traditional Chinese veterinary drug for treating mastitis of dairy cows and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110682A (en) * | 2011-11-16 | 2013-05-22 | 李洪梅 | Research on treatment of cow mastitis through traditional Chinese medicine |
-
2013
- 2013-11-18 CN CN201310576045.9A patent/CN103655948A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110682A (en) * | 2011-11-16 | 2013-05-22 | 李洪梅 | Research on treatment of cow mastitis through traditional Chinese medicine |
Non-Patent Citations (2)
| Title |
|---|
| 张国红等: "中草药防治奶牛***炎的研究进展", 《畜禽业》 * |
| 易湘蓉等: "中草药防治奶牛乳腺炎的研究综述", 《上海畜牧兽医通讯》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367715A (en) * | 2014-12-03 | 2015-02-25 | 徐自升 | Pure Chinese medicine compound for prevention and treatment of mastitis of dairy cows and preparation method thereof |
| CN104758432A (en) * | 2014-12-10 | 2015-07-08 | 北京康华远景科技股份有限公司 | Botanical drug preparation for treating mastitis of dairy cow and preparation method thereof |
| CN104758432B (en) * | 2014-12-10 | 2018-06-19 | 北京康华远景科技股份有限公司 | A kind of autonomic drug preparation for treating mastitis for milk cows and preparation method thereof |
| CN106344724A (en) * | 2016-10-27 | 2017-01-25 | 成都乾坤动物药业股份有限公司 | Traditional Chinese veterinary drug for treating mastitis of dairy cows and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA029649B1 (en) | Pomegranate-peel polyphenol gel used to treat gynecological inflammation diseases and method for preparation thereof | |
| CN103655948A (en) | Traditional Chinese veterinary medicine injection for treating cow mastitis and preparation method thereof | |
| CN102406766B (en) | Traditional Chinese medicine composition for treating bone fracture and application thereof | |
| CN109620879A (en) | A kind of wet repairing paste and preparation method thereof clearly | |
| CN102631589A (en) | Penyanxiao enema and preparation method thereof | |
| CN106214740A (en) | A kind of Chinese medicine composition and its production and use | |
| CN110302273A (en) | A kind of Traditional Chinese medicine bacteriostatic gel and its preparation method and application | |
| CN108403570A (en) | There are the body condensation and preparation method of improvement to pruitus caused by eczema | |
| CN104274619A (en) | Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition | |
| CN104306909B (en) | Prevent and treat Chinese medicine composition of cattle uterus subinvolution and preparation method thereof | |
| CN102824440B (en) | Traditional Chinese medicine composition for treating dairy cow mastitis and preparation method thereof | |
| CN112156225A (en) | Chitosan or and algal polysaccharide composite biological matrix liquid dressing gel preparation and preparation method thereof | |
| CN102302575B (en) | Oral medicament for treating white scour of piglets and preparation method thereof | |
| CN107029040B (en) | Compound traditional Chinese medicine powder for treating cow subclinical mastitis | |
| CN105125639A (en) | Traditional Chinese medicine composition for preventing and treating mastitis of dairy cattle | |
| CN103720930B (en) | A kind of Chinese medicine composition treating bovine mastitis | |
| CN103720927A (en) | Traditional Chinese medicine preparation for treating dairy cow mastitis | |
| CN108567868A (en) | A kind of routed more external medicine composition and preparation method thereof of skin care | |
| CN103893259A (en) | Novel traditional Chinese medicine composition for controlling recessive mastitis and preparation method thereof | |
| CN108578551A (en) | Treat the Chinese medicine film and preparation method thereof of foot rot | |
| CN107951972A (en) | Apply medicinal lotion or ointment outside a kind of Chinese traditional medicine composition for treating mastitis for milk cows thing and preparation method thereof | |
| CN108186807A (en) | A kind of Chinese medicine composition for treating perianal | |
| CN103127274A (en) | All-season burn and scald medicine for seasons | |
| CN110038028B (en) | Preparation for treating phlebitis and application | |
| CN105853555A (en) | Medical microfilament for treating burns and scalds and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| AD01 | Patent right deemed abandoned |
Effective date of abandoning: 20161116 |
|
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |