CN103623289A - Traditional Chinese medicine preparation for treating alopecia and preparation method of preparation - Google Patents
Traditional Chinese medicine preparation for treating alopecia and preparation method of preparation Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating alopecia and a preparation method of the preparation. The preparation is prepared from the following traditional herbal raw materials in parts by weight: 40-50 parts of unprepared rehmannia roots, 30-50 parts of radix scrophulariae, 30-50 parts of radix ophiopogonis, 8-15 parts of ephedra, 10-15 parts of cassia twig, 50-70 parts of radix pseudostellariae, 20-40 parts of astragalus membranaceus, 20-40 parts of Chinese yam, 20-40 parts of houttuynia cordata, 20-40 parts of coix seed, 10-20 parts of schefflera arboricola, 20-40 parts of cacumen biotae, 15-30 parts of fleece-flower root, 10-20 parts of perilla leaf, and 10-25 parts of medical stone. The preparation is remarkable in curative effect, high in cure rate and low in recurrence rate, and prevents side effects caused by the traditional external abrasive cleaner.
Description
Technical field:
The present invention relates to technical field of Chinese medicines, is exactly a kind of Chinese medicine preparation and preparation method of hair growth specifically.
Background technology:
Alopecia or title alopecia are a kind of common hair diseases.Its kind is more, as congenital alopecia, posteriority alopecia, alopecia cicatrisata, alopecia areata and seborrheic alopecia etc.Wherein modal is the alopecia of fat mountain pass, is secondly alopecia areata.They are more common in person between twenty and fifty, due to impact beauty treatment, often to patient, bring a lot of worries and misery.
The traditional Chinese medical science is thought hair is the sign of blood condition, therefore when people's deficiency of liver-blood, and deficiency of kidney-QI, hair becomes pale, and easily what comes off.Along with the fast development of China's economy, people are at life, work, pressure in study also in continuous increase, and the continuous quickening of rhythm of life, has caused people's rule of life also often disorderly.This is serious the healthy of people that affect all.Therefore when human body self dysfunction, the growth conditions of hair has suffered destruction, and alopecia also just usually occurs.According to relevant statistics, the sickness rate of China's alopecia is up to 20-24%, that is to say that alopecia morbidity crowd that several hundred million people are perplexed Zhe，Er China by alopecia is when increasing year by year, and morbidity crowd also presents rejuvenation.
The problems such as at present, Western medicine there is no specific treatment method for alopecia, and uses existing Chinese traditional patent formulation hair growth usually to occur unsatisfactory curative effect, and the course for the treatment of is long.
Summary of the invention:
The present invention is exactly in order to overcome the deficiency to alopeciaing therapeutic in prior art, provide a kind of for alopeciaing therapeutic have that curative effect is fast, short treating period, to control recurrence rate after healing low, and the Chinese medicine preparation having no side effect.
Another problem that the present invention need to solve is exactly the preparation method of described Chinese medicine preparation.
Technical scheme provided by the present invention is as follows:
The Chinese medicine preparation of hair growth and a preparation method, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Rehmanniae 40-50 part, Radix Scrophulariae 30-50 part, Radix Ophiopogonis 30-50 part, Herba Ephedrae 8-15 part, Ramulus Cinnamomi 10-15 part, Radix Pseudostellariae 50-70 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 20-40 part, Herba Houttuyniae 20-40 part, Semen Coicis 20-40 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Cacumen Platycladi 20-40 part, Radix Polygoni Multiflori 15-30 part, Folium Perillae 10-20 part, Maifanitum 10-25 part.
Be preferably:
50 parts, the Radix Rehmanniae, 40 parts of Radix Scrophulariae, 40 parts of Radix Ophiopogonis, 12 parts, Herba Ephedrae, 12 parts of Ramulus Cinnamomi, 60 parts of Radix Pseudostellariaes, 30 parts of the Radixs Astragali, 30 parts of Rhizoma Dioscoreaes, 30 parts of Herba Houttuyniae, 30 parts of Semen Coicis, 15 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 30 parts of Cacumen Platycladis, 20 parts of the Radixs Polygoni Multiflori, 15 parts of Folium Perillae, 20 parts of Maifanitums.
The preparation method concrete steps of Chinese medicine preparation of the present invention are following 1, the raw material of Chinese medicine of described weight proportion is cleaned for several times with 5% saline, then, rinsing for several times with clear water, finally put into drying baker and dry; 2, the raw material of Chinese medicine drying is mixed, be crushed to 100 to 200 object coarse powder; 3, by described coarse powder by 65% soak with ethanol after 72 hours, by carrying out the vacuum back-flow of 3 times, extraction, by after gained liquid filtering standing 48 hours, filter and remove residue added distilled water diluting concentration of alcohol to 7%-5% sterilizing, 150ml bottling under aseptic condition.
Raw material of Chinese medicine used in the present invention through inventor study for many years and Chinese medical discrimination in for alopecia rationale: " alopecia belongs to deficiency of liver-blood, deficiency of kidney-essence, stagnation of liver-QI, and blood deficiency, blood deficiency are sent out not flourish." the present invention is according to theory of Chinese medical science and herbal nature, with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, nourishing YIN and benefiting blood is basis, by regulating vim and vigour running, hair follicle stimulating regeneration, thus reach the object of hair growth.Effect and the pharmacological action of each raw material of Chinese medicine used in the present invention are as follows:
The Radix Rehmanniae: sweet in the mouth, cold in nature.GUIXIN, liver, kidney channel.There is clearing away heat and cooling blood, the effect of YIN nourishing and the production of body fluid promoting.Experiment shows: Radix Rehmanniae decoct gavage has obvious antagonism to rat formaldehyde arthritis and albumen arthritis, and can suppress the increase of the capillary permeability that granuloma that Oleum Terebinthinae subcutaneous injection causes and histamine cause.The mouse peritoneum inflammation that the vascular permeability that Rehmannia glutinosa Libosch Water extracting solution causes histamine increases and acetic acid causes has obvious inhibitory action, and Ovum Gallus domesticus album induced Acute inflammation is also had to antiinflammatory action.During Bufo siccus back leg perfusion Radix Rehmanniae extractum, intermediate concentration makes vasoconstriction, and high concentration distends the blood vessels.
Radix Scrophulariae: sweet in the mouth, hardship, salty, cold in nature.Return lung, stomach, kidney channel.There is clearing away heat and cooling blood, the effect of YIN nourishing removing toxic substances.Research shows: this product all has inhibitory action to various bacteria such as staphylococcus aureus, Bacillus typhi.Infusion or decoct have the effect of blood pressure lowering; Alcohol extractum aqueous solution can obviously increase coronary flow.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature.GUIXIN, lung, stomach warp.There is nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire.This product decoct can improve laboratory animal hypoxia-bearing capability, increases coronary flow, and myocardial ischemia is had to obvious protective effect, and can arrhythmia and improve the effects such as myocardial contraction.
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature.Return lung, urinary bladder channel.There is relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema.This product volatile oil has diaphoresis, refrigeration function.Ephedrine and pseudoephedrine can be alleviated bronchial muscular spasm, and ephedrine has the effect of excited heart, vasoconstrictive, rising blood pressure, excited maincenter.This product also has the effects such as antiinflammatory, antibacterial, antiviral.
Ramulus Cinnamomi: its nature and flavor are pungent, sweet, enter liver,kidney,spleen, to cure mainly the conventional drugs for dispelling internal cold of interior cold, the effect with complement sun, promoting blood circulation, warming the spleen and stomach, normal and invigorating the liver and kidney medicine, medicine compatibility fills blood, treatment insufficiency of kidney-YANG, decline of the fire from the gate of life, cold extremities faint pulse, with other drugs for dispelling internal cold compatibility treatment coldness and pain in the epigastrium, arthralgia due to cold lumbago, have the effect of obvious analgesia and anti-cancer and cancer-preventing.
Radix Pseudostellariae: sweet in the mouth, micro-hardship, property is flat.Return spleen, lung meridian.The effect with tonifying QI to produce body fluid.This product can QI invigorating, again can YIN nourishing and the production of body fluid promoting, and the efficacy of a drug is gentle, and be the product of clear benefits simply, be applicable to spleen lung virtual loss, deficiency of both vital energy and Yin, all diseases of gas Tianjin deficiency; Lymphocyte is had to obvious stimulation.
The Radix Astragali: sweet in the mouth, slightly warm in nature.Return lung, spleen, liver, kidney channel.Have tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, the effect of holder skin ulcer granulation promoting.The decoct of this product has enhancing immunity, protects the liver, improves renal function, diuresis, improves hemorheological property, promotes the effects such as hemopoietic function, defying age, anti-stress, removing toxic substances, antibacterial, antiviral, antitumor.The effects such as contained Radix Astragali saponin has blood vessel dilating, blood pressure lowering, heart tonifying, raising cardiac muscle oxygen-resistant ability, resists myocardial ischemia, antiinflammatory.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.The positive > > of tool < < book on Chinese herbal medicine records: Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, and controls weakness, treats five kinds of strain and seven kinds of impairment.The light property of its gas is slow, non-may be full-time, therefore spleen reinforcing lung must mainly be joined, art, the kidney invigorating water must monarch Zhu,, puckery foul leukorrhea must be broken therefore with grinding, solid spermatorrhea is held Herba cuscutae and helped mutually.All balls consolidate pill, also should smash end for sticking with paste.Nature and flavor are weak in a word, but can firmly help and make.
Herba Houttuyniae: cold nature, bitter in the mouth.Return lung meridian, bladder, large intestine channel.Record to this product in < < Japan hanako materia medica > >: " simmer in phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle cylinder, deposited malignant boil is bald in vain ".
Semen Coicis: sweet in the mouth, cold in nature.Return spleen, stomach, lung meridian.There is promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, heat clearing away is got rid of, the effects such as eliminating impediment.In < < Compendium of Materia Medica > > for the record of this product: " positive bright medicine also, can invigorating spleen and reinforcing stomach.Reinforcing the mother-organ for treating deficiency of the son-organ, therefore consumptive lung disease, lung abscess are used it.The disease of muscles and bones, take Zhi Yangming as this, therefore contracture muscular contracture migratory arthralgia person uses it.Soil can win water dehumidifying, thus have loose bowels edema with it ".The ethanol extract of this product has anticancer, antibacterial effect.
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): bitter in the mouth, warm in nature.Enter lung, kidney,liver,spleen four warps.There is relaxing muscles and tendons and activating QI and blood in the collateral, circulation of qi promoting damp eliminating, the effect such as cold expelling dispels the wind, eliminating dampness to stop diarrhea.
Cacumen Platycladi: bitter in the mouth, puckery, cold nature.Return lung, liver, large intestine channel.The record to this product in > > is wanted in tool < < medical center bun: " let out lung contrary, eliminating heart-fire, suppressing the hyperactive liver is warm, the heat purifying the blood minute ".Cacumen Platycladi decoct can obviously shorten bleeding time and clotting time, and its hemostasis effective ingredient is Quercetin and tannin.In addition effects such as, still having antitussive, eliminate the phlegm, relieving asthma, be calm.Experiment in vitro shows, these product all have inhibitory action to staphylococcus aureus, micrococcus catarrhalis, dysentery bacterium, Bacillus typhi, diphtheria corynebacterium etc.
The Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature.Return liver, kidney channel.There is nourishing the blood and yin, black beard and hair, strengthening bone and muscle, the effect of controlling nocturnal emission with astringent drugs gas.This product is rich in lecithin, has the hemocyte of promotion new life and grows, and increases the effect of liver glycogen.Also there is the effects such as enhancing immunity, defying age, increase coronary flow, antibacterial, antiviral.
Folium Perillae: acrid in the mouth, slightly warm in nature.Return spleen, lung meridian.There is relieving the exterior syndrome by diaphoresis, the effects such as promoting the circulation of QI to alleviate the stagnation in middle-JIAO.The water decoction of this product and alcohol immersion all have skin expansion blood vessel, stimulate the effect of sweat gland secretion, in addition also have the secretion of facilitating digestion liquid, increase the effects such as gastrointestinal peristalsis.
Maifanitum: harmful several units such as cadmium, hydrargyrum, arsenic, lead are have to stronger absorbability.Experimental result shows, Maifanitum has resisting fatigue, oxygen lack resistant function to mice.
The invention has the advantages that: adopt natural Chinese medicines to make, with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, nourishing YIN and benefiting blood is basis, by regulating vim and vigour running, hair follicle stimulating regeneration, thereby reach the object of hair growth, have evident in efficacyly, cure rate is high, relapse rate is low, and has avoided the side effect of using traditional external abrasive cleaner to cause.
The specific embodiment:
Embodiment 1:
Optimization formula of the present invention: 50 parts, the Radix Rehmanniae, 40 parts of Radix Scrophulariae, 40 parts of Radix Ophiopogonis, 12 parts, Herba Ephedrae, 12 parts of Ramulus Cinnamomi, 60 parts of Radix Pseudostellariaes, 30 parts of the Radixs Astragali, 30 parts of Rhizoma Dioscoreaes, 30 parts of Herba Houttuyniae, 30 parts of Semen Coicis, 15 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 30 parts of Cacumen Platycladis, 20 parts of the Radixs Polygoni Multiflori, 15 parts of Folium Perillae, 20 parts of Maifanitums.
Preparation method:
Concrete steps prepared by Chinese medicine preparation of the present invention are as follows: 1, the raw material of Chinese medicine of described weight proportion is cleaned for several times with 5% saline, then, rinsing for several times with clear water, finally put into drying baker and dry; 2, the raw material of Chinese medicine drying is mixed, be crushed to 100 to 200 object coarse powder; 3, by described coarse powder by 65% soak with ethanol after 72 hours, by carrying out the vacuum back-flow of 3 times, extraction, by after gained liquid filtering standing 48 hours, filter and remove residue added distilled water diluting concentration of alcohol to 7%-5% sterilizing, aseptic 150ml bottling.
Embodiment 2:
Using method of the present invention: morning, noon and afternoon every day after meal, are taken 50ml one week is a course for the treatment of.
Inventor uses Chinese medicine preparation of the present invention to treat 103 patients for many years, male's 64 examples wherein, and women's 39 examples, 36 years old patient's mean age, alopecia areata, alopecia universalis, alopecia totalis account for 43 examples, and seborrheic alopecia accounts for 60 examples.Use the present invention to treat after 4 courses for the treatment of, 43 examples of fully recovering, account for 41.74% of total number of persons, and 53 examples that take a turn for the better, account for 51.45% of total number of persons, and invalid 7 examples account for 6.54% of total number of persons.
Criterion of therapeutical effect is as follows:
Recovery from illness: hair stops coming off, and new regeneration rate reaches more than 75%, and head sebum secretion significantly reduces.
Take a turn for the better: alopecia situation has bright improvement, and new regeneration rate reaches more than 15%.
Invalid: with obviously difference of nothing before treatment.
Model case:
1, Zhang, female, 45 years old, within 04 year, play unknown cause and start alopecia, through multi-treatment, without any improvement, within 09 year, start to take Chinese medicine preparation of the present invention, after treating 2 courses for the treatment of, alopecia phenomenon stops, and the top of the head has trickle fine hair to grow, have continue medication treatment after 1 month hair be as good as with ordinary person, do not recur so far.
2, Lee, man, suffers from alopecia areata for 38 years old for many years, through multi-treatment without any improvement, after within 10 years, starting to take 4 courses for the treatment of of Chinese medicine preparation of the present invention treatment, effect is remarkable, continues again to fully recover after medication treatment one and a half months, and drug withdrawal does not have the phenomenon that hair comes off again to occur over 2 years.
Claims (3)
1. the Chinese medicine preparation of hair growth and a preparation method, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Rehmanniae 40-50 part, Radix Scrophulariae 30-50 part, Radix Ophiopogonis 30-50 part, Herba Ephedrae 8-15 part, Ramulus Cinnamomi 10-15 part, Radix Pseudostellariae 50-70 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 20-40 part, Herba Houttuyniae 20-40 part, Semen Coicis 20-40 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Cacumen Platycladi 20-40 part, Radix Polygoni Multiflori 15-30 part, Folium Perillae 10-20 part, Maifanitum 10-25 part.
2. according to the Chinese medicine preparation of a kind of hair growth described in claim 1 and preparation method, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 50 parts, the Radix Rehmanniae, 40 parts of Radix Scrophulariae, 40 parts of Radix Ophiopogonis, 12 parts, Herba Ephedrae, 12 parts of Ramulus Cinnamomi, 60 parts of Radix Pseudostellariaes, 30 parts of the Radixs Astragali, 30 parts of Rhizoma Dioscoreaes, 30 parts of Herba Houttuyniae, 30 parts of Semen Coicis, 15 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 30 parts of Cacumen Platycladis, 20 parts of the Radixs Polygoni Multiflori, 15 parts of Folium Perillae, 20 parts of Maifanitums.
3. according to Chinese medicine preparation and the preparation method of a kind of hair growth described in claim 1,2, it is characterized in that: the preparation method concrete steps of described Chinese medicine preparation are as follows: 1, the raw material of Chinese medicine of described weight proportion is cleaned for several times with 5% saline, then, rinsing for several times with clear water, finally put into drying baker and dry; 2, the raw material of Chinese medicine drying is mixed, be crushed to 100 to 200 object coarse powder; 3, by described coarse powder by 65% soak with ethanol after 72 hours, by carrying out the vacuum back-flow of 3 times, extraction, by after gained liquid filtering standing 48 hours, filter and remove residue added distilled water diluting concentration of alcohol to 7%-5% sterilizing, 150ml bottling under aseptic condition.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105533010A (en) * | 2014-10-29 | 2016-05-04 | 崔成哲 | Perilla frutescens hair tea with functions of alopecia prevention and hair growth, and production method thereof |
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| CN101804138A (en) * | 2010-05-08 | 2010-08-18 | 万明忠 | Traditional Chinese medicine compound preparation for treating alopecia and preparation method thereof |
| CN102309685A (en) * | 2010-06-29 | 2012-01-11 | 财团法人台湾必安研究所 | Chinese medicinal composition for promoting hair growth |
| CN103405620A (en) * | 2013-08-09 | 2013-11-27 | 陕西步长高新制药有限公司 | Chinese herbal preparation for treatment of seborrheic alopecia and alopecia areata and preparation method of Chinese herbal preparation |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804138A (en) * | 2010-05-08 | 2010-08-18 | 万明忠 | Traditional Chinese medicine compound preparation for treating alopecia and preparation method thereof |
| CN102309685A (en) * | 2010-06-29 | 2012-01-11 | 财团法人台湾必安研究所 | Chinese medicinal composition for promoting hair growth |
| CN103405620A (en) * | 2013-08-09 | 2013-11-27 | 陕西步长高新制药有限公司 | Chinese herbal preparation for treatment of seborrheic alopecia and alopecia areata and preparation method of Chinese herbal preparation |
Non-Patent Citations (2)
| Title |
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| 闫若庸等: "白长川教授治疗顽固性脱发经验", 《中华中医药杂志》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105533010A (en) * | 2014-10-29 | 2016-05-04 | 崔成哲 | Perilla frutescens hair tea with functions of alopecia prevention and hair growth, and production method thereof |
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