CN103623280B - A kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease - Google Patents
A kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Semen Sesami Nigrum, Rhizoma Dioscoreae, Radix Puerariae, Amaranthus mangostanus L., Semen Ginkgo, the Cortex Eucommiae, Radix Polygoni Multiflori, Folium Evodiae trichotomae, Radix Salviae Miltiorrhizae, Radix Dauci Sativae, Lentinus Edodes, Auricularia, Herba Urticae Cannabinae, Fructus Crataegi, Thallus Gracilariae and Germinatus Phragmitis; Chinese medicine preparation of the present invention has effect of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, phencyclidine, heat-clearing and toxic substances removing, to the symptom alleviating the cardiovascular and cerebrovascular vessel such as the hemiplegia of limb caused by hyperlipidemia, hypertension, coronary heart disease, cerebral infarction, pained, dizzy, cardiopalmus uncomfortable in chest, headache, there is significant curative effect, and there is the advantages such as preparation technology is simple, cost is lower, without any side effects, be worth wide popularization and application clinically.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease.
Background technology
Cardiovascular and cerebrovascular disease is exactly that cardiovascular and cerebrovascular disease are referred to as.Cardiovascular and cerebrovascular disease is a kind of serious threat mankind, the particularly commonly encountered diseases of more than 50 years old middle-aged and elderly people health, even if apply treatment means most advanced, perfect at present, the cerebrovas-cularaccident survivor of more than 50% still can be had to live can not take care of oneself completely, cardiovascular and cerebrovascular disease has become the highest number one killer of human death's cause of disease, is also health of people " noiseless demon ".
Cardiovascular and cerebrovascular disease has the feature of " four is high by more than " that sickness rate is high, disability rate is high, mortality rate is high, relapse rate is high and complication is many.
At present, China's Patients with Cardiovascular/Cerebrovascular Diseases is more than 2.7 hundred million people, and China dies from nearly 3,000,000 people of cardiovascular and cerebrovascular disease every year, accounts for 51% of the annual total Death causes of China, and patient 75% disability in various degree survived, 40% is heavy residual.China's patient with cerebral apoplexy leave hospital after the relapse rate of First Year be 30%, the relapse rate of the 5th year up to 59%, and secondary prevention do preferably the U.S. be only 10%.
Treatment at present for cardiovascular and cerebrovascular vessel does not have specific medicine, particularly usually use the medicine of some chemicals over the course for the treatment of, the side effect of these medicines is larger, very large infringement can be brought to other organs of user in the process using these chemicals medicines, and after drug withdrawal in the short time state of an illness will recur, therefore, research and develop the medicine of new treatment cardiovascular and cerebrovascular disease, be the focus of pharmaceutical researchers always.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease; Chinese medicine preparation of the present invention has effect of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, phencyclidine, heat-clearing and toxic substances removing, to the symptom alleviating the cardiovascular and cerebrovascular vessel such as the hemiplegia of limb caused by hyperlipidemia, hypertension, coronary heart disease, cerebral infarction, pained, dizzy, cardiopalmus uncomfortable in chest, headache, there is significant curative effect, and there is the advantages such as preparation technology is simple, cost is lower, without any side effects, be worth wide popularization and application clinically.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for cardiovascular and cerebrovascular disease, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of cardiovascular and cerebrovascular disease, comprise following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density under 60 DEG C of environment is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, being condensed into relative density under 70 DEG C of environment is the thick paste of 1.20 ~ 1.25, for subsequent use;
(5) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (4), utilize modern advanced pharmacy science and technology, make tablet, obtain the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Semen Sesami Nigrum: sweet in the mouth, property is put down; Enter liver, kidney, lung, spleen channel.Enrich blood improving eyesight, intestine moistening of dispeling the wind, promote the production of body fluid lactogenesis, the liver benefiting hair care, keeps fit body, defying age.Can be used for treating physical weakness, dizziness and tinnitus, hypertension, hyperlipidemia, cough, physical weakness, early whitening of hair, anemia is sallow, deficiency of body fluid, constipation due to dry stool, and breast is few, the diseases such as hematuria.Compendium of Material Medica is carried: " can be used for that Liver and kidney two is empty, muscles and bones is strong, extremity are aching and limp unable etc.”
Rhizoma Dioscoreae: sweet in the mouth, property is put down; Enter spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, control weakness, treat five kinds of strain and seven kinds of impairment.The light property of its gas is delayed, non-may be full-time, therefore spleen reinforcing lung must mainly be joined, art, the kidney invigorating water must monarch Zhu, puckery foul leukorrhea must be broken therefore with grinding, solid spermatorrhea battle Herba cuscutae helps mutually, and all balls consolidate pill, and also should smash end for paste, nature and flavor are weak in a word, but firmly can help and make.”
Radix Puerariae: sweet in the mouth, pungent, cool in nature; Enter spleen, stomach warp.Induce sweat and bring down a fever, rash of promoting the production of body fluid, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels.Compendium of Material Medica is carried: " Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling." modern medicine study shows, the isoflavonoid puerarin in Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Amaranthus mangostanus L.: taste is micro-sweet, cool in nature; Enter lung, large intestine channel.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, dysentery relieving.Cure mainly dysentery, constipation and anuresis, conjunctival congestion pharyngalgia, the diseases such as epistaxis." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control sphincter disturbance, change worm, cold removing heat, energy promoting blood circulation, removing blood stasis blood.”
Semen Ginkgo: sweet in the mouth, hardship, puckery, property is put down; Enter lung, kidney channel.Astringe the lung gas, relieving asthma and cough, leukorrhagia stopping is turbid, urine reducing, disinfection.Cure mainly asthma, phlegmatic cough, nocturnal emission, leucorrhea, nebulousurine, infantile diarrhea, malnutrition due to parasitic infestation, hemorrhoidal hamorrhage dysentery, gonorrhea, frequent micturition, and the disease such as scabies, dermatitis rhus, in vain tumor wind." herbal classic meets source " carries: " in carry a Semen Ginkgo and have the function of falling expectorant, detoxicating, parasite killing, skin ulcer scabies cellulitis tumor can be treated, acute mastitis is festered, tooth worm dental caries, infantile diarrhea, leucorrhea with red and white discharge, chronic stranguria with turbid discharge, disease such as the seminal emission enuresis etc." modern medicine study confirmation, Semen Ginkgo has certain effect to disease such as treatment hypertension and coronary heart diseases and angina pectoris, cerebral vasospasm, hypercholesterolemia etc.
The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening.Cure mainly spinal column ache, rheumatic arthralgia.Carry according to Prescriptions Worth Thousand Gold for Emergencies: " liver and kidney tonifying, fills blood for function wind-damp dispelling, stopping numbness pain, damp of having a cold, chills and pain of the waist and kness, podomere joint stuffiness, or benumbs meciless, fear of cold happiness temperature." modern medicine study confirms, the Cortex Eucommiae has sedation to nerve centre, can strengthen the immunologic function of cell, promotes cortisol secretion and cAMP in plasma and cGMP metabolism.
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver, kidney channel.Enrich and benefit essence and blood, removing toxic substances preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.Cure mainly blood deficiency anemia, Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, hemorrhoid." book on Chinese herbal medicine is stated " carries: " control apoplexy, headache, migratory arthralgia, the arthroncus of knee, epilepsy syndrome, jaundice.”
Folium Evodiae trichotomae: acrid in the mouth, hardship, warm in nature; Attach to the lung and stomach meridians.Expelling wind and removing dampness, dispersing cold for relieving pain.Cure mainly your disease after poliomyelitis, rheumatic arthritis, eczema, urticaria, skin infection, headche due to wind-cold." choosing of Simao, Yunnan Chinese herbal medicine " carries: " control poliomyelitis sequela, rheumatic arthritis, urticaria, eczema, skin sore is itched.”
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature; Enter the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, evacuation of pus granulation promoting.For menoxenia, blood stasis is had a pain, amenorrhea, lump in the abdomen, coronary heart disease, angina pectoris, ectopic pregnancy, vexed interior-heat, carbuncle sore tumefacting virus etc." Japan hanako materia medica " carries: " sedate of reposing, tonneau GUAN-pulse.Control cold and hot labor, arthralgia, extremity are unsuccessful, evacuation of pus pain relieving, and granulation promoting is put on flesh, broken stagnated blood, and mend new hemopoietic, peaceful tire, fall stillborn fetus, and under hemostasis metrorrhagia and leukorrhagia, adjust married woman's passages through which vital energy circulates irregular, blood evil thought is tired of, malignant boil scabies, and wart is gone to live in the household of one's in-laws on getting married toxic swelling, and erysipelas, headache, acute conjunctivitis, hot temperature is mad vexed.”
Radix Dauci Sativae: sweet in the mouth, pungent, warm in nature, nontoxic.Strengthening the spleen to promote digestion, tonifying liver improving eyesight, heat-clearing and toxic substances removing, rash, sending down the abnormal ascending QI cough-relieving.For infantile malnutrition, measles, nyctalopia, constipation, hypertension, gastrointestinal upset, chronic dysentery, full stifling is swollen." daily book on Chinese herbal medicine " carries: " the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, loose stomach is possessed stagnant.”
Lentinus Edodes: sweet in the mouth, property is put down, nontoxic.Blood pressure lowering, blood fat reducing, cholesterol reducing.Cure mainly QI invigorating not hungry, control wind removing blood stasis, the deficiency of vital energy is dizzy, anemia, leukopenia, self-resistance declines and elderly and infirm should eat, hyperlipemia, hypertension, arteriosclerosis, diabetes, overweight people should eat, and should eat after cancer patient and cancer patient's radiotherapy, chemotherapy, acute, chronic hepatitis, fatty liver, cholelithiasis, constipation person.
Auricularia: sweet in the mouth, property is put down, slightly poisonous.Modern medicine study confirm, Auricularia is applicable to cardiovascular and cerebrovascular disease, calculosis edible for patients, be particularly suitable for the personage of iron deficiency, miner, metallurgical workman, weaving work, hairdresser eat.
Herba Urticae Cannabinae: bitter in the mouth, pungent, warm in nature, poisonous.Dispelling wind and removing obstruction in the collateral, suppressing the hyperactive liver is calmed the frightened, removing food stagnancy relieving constipation, removing toxic substances.Cure mainly rheumatic arthralgia, puerperal convulsion, infantile convulsion, poliomyelitis sequela, hypertension, dyspepsia, constipation, urticaria, traumatic injury, worm venom." discriminating of Heilungkiang Main Wild Medicinal plant and Chinese herbal medicine novel formulation " carries: " control poliomyelitis, rheumatism, colic.”
Fructus Crataegi: sweet in the mouth, acid, slightly warm in nature.Removing food stagnancy, clots absorbing, changes stagnant." daily book on Chinese herbal medicine " carries: " relieving dyspepsia is amassed, row stagnation of QI, the wide diaphragm of stomach invigorating, the blood mass at the hypochondrium that disappears block." modern medicine study confirms, Fructus Crataegi has blood vessel dilating, increases coronary flow, improves heart vigor, stimulating central nervous system system, reduce blood pressure and cholesterol, vessel softening and diuresis and sedation.
Thallus Gracilariae: sweet in the mouth, cold in nature; Return spleen channel.Hard masses softening and resolving, heat-clearing and toxic substances removing, dampness removing is aid digestion.Modern medicine study confirms, Thallus Gracilariae lung heat clearing relieving constipation, and skin care is reduced weight, can blood pressure lowering, blood fat reducing, adjustment physical function, enhancing immunity.
Germinatus Phragmitis: sweet in the mouth, hardship, cool in nature.Lung moistening antitussive, eliminate the phlegm parasite killing.Cure mainly heart disease, hypertension, tachycardias, fatigue, edema, cystitis, dysuria.Modern medicine study confirms, Germinatus Phragmitis is applicable to hypertension, hyperlipemia, cancer, arteriosclerotic eat, be also simultaneously have a delicate constitution, insufficiency of vital energy and blood, malnutrition, anemia, obesity and habitual constipation person and hepatic insufficiency, oedema due to nephritis, lithangiuria person first-selection.
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has effect of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, phencyclidine, heat-clearing and toxic substances removing, to the symptom alleviating the cardiovascular and cerebrovascular vessel such as the hemiplegia of limb caused by hyperlipidemia, hypertension, coronary heart disease, cerebral infarction, pained, dizzy, cardiopalmus uncomfortable in chest, headache, there is significant curative effect, and there is the advantages such as preparation technology is simple, cost is lower, without any side effects, be worth wide popularization and application clinically.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density under 60 DEG C of environment is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, being condensed into relative density under 70 DEG C of environment is the thick paste of 1.20 ~ 1.25, for subsequent use;
(5) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (4), utilize modern advanced pharmacy science and technology, make tablet, obtain the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease, Patients with Cardiovascular/Cerebrovascular Diseases 200 example made a definite diagnosis is selected to carry out clinical observation, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 54 example, women 46 example, 41 ~ 76 years old age, 55.8 years old mean age, the shortest person of the course of disease 2 months, most elder 5 years, average 3.1 years.Matched group 100 example, wherein male 53 example, women 47 example, 43 ~ 78 years old age, 43.5 years old mean age, the shortest person of the course of disease 3 months, most elder 4 years, average 2.7 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Matched group takes nitroglycerin, sublingual administration a slice nitroglycerin, as ineffective, every 5 minutes again containing changing a slice, can continuous application three times, and be generally no more than three times; Within 9 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3 ~ 4 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction all disappear, electrocardiogram display ischemic state recovers normal.
(2) effective: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction alleviate or attack times reduces, electrocardiogram display myocardial ischemia improves
(3) effective: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction disappear substantially, electrocardiogram display ischemic state recovers normal substantially.
(4) invalid: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction have no improvement.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 43 examples, effective 32 examples, effective 22 examples, invalid 3 examples, cure rate 43%, total effective rate 97%.
13 examples are cured, effective 19 examples, effective 11 examples, invalid 57 examples, cure rate 13%, total effective rate 43% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, fourth, female, 48 years old, ShenZhen,GuangDong people.Patient suffers from cerebrovascular for many years, removes examination in hospital, is diagnosed as cardiovascular and cerebrovascular disease, uses multiple Drug therapy, and has no sign of improvement.To our hospital afterwards, take Chinese medicine preparation of the present invention, fully recover after taking 1 course for the treatment of.
2, Feng, man, 55 years old, people from Yantai, Shandong.Patient suffers from hypertension and headache, uses multiple Drug therapy, poor effect.To our hospital, take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, symptom disappears substantially, and after taking the 2nd course for the treatment of, symptom all disappears.
3, certain is permitted, man, 68 years old, people from Nanjing.Patient suffers from hyperlipidemia, hypertension for many years, removes hospital admission, is diagnosed as cardiovascular and cerebrovascular disease.Take Chinese medicine preparation of the present invention, every day 2 times, each 1 time sooner or later, each 2, after taking 1 course for the treatment of, symptom makes moderate progress, and takes transference cure after 2 courses for the treatment of, follows up a case by regular visits to, do not recur so far.
4, Luo, female, 72 years old, Shandong region people.Patient suffers from cardiovascular and cerebrovascular disease, and blood pressure, blood fat continue to raise, and use many Drug therapys, and lose improvement.To our hospital afterwards, take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, symptom disappears substantially, and after continuing to take 1 course for the treatment of, above symptom disappears completely, follows up a case by regular visits to, and does not recur so far.
Claims (5)
1. treat a Chinese medicine preparation for cardiovascular and cerebrovascular disease, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Sesami Nigrum 60 ~ 85 portions of Rhizoma Dioscoreaes 50 ~ 85 parts of Radix Puerariaes 50 ~ 80 parts of Amaranthus mangostanus L.s 45 ~ 80 parts
Semen Ginkgo 40 ~ 80 parts of Cortexs Eucommiae 40 ~ 75 parts of Radix Polygoni Multiflori 40 ~ 70 parts of Folium Evodiae trichotomae 35 ~ 70 parts
25 ~ 55 parts, Radix Salviae Miltiorrhizae 35 ~ 65 portions of Radix Dauci Sativaes 30 ~ 60 parts of Lentinus Edodess 30 ~ 55 portions of Auricularias
Herba Urticae Cannabinae 20 ~ 50 portions of Fructus Crataegis 20 ~ 45 portions of Thallus Gracilariaes 15 ~ 45 portions of Germinatus Phragmitiss 15 ~ 40 parts.
2. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Sesami Nigrum 65 ~ 80 portions of Rhizoma Dioscoreaes 55 ~ 80 parts of Radix Puerariaes 55 ~ 75 parts of Amaranthus mangostanus L.s 50 ~ 75 parts
Semen Ginkgo 45 ~ 75 parts of Cortexs Eucommiae 45 ~ 70 parts of Radix Polygoni Multiflori 45 ~ 65 parts of Folium Evodiae trichotomae 40 ~ 65 parts
30 ~ 50 parts, Radix Salviae Miltiorrhizae 40 ~ 60 portions of Radix Dauci Sativaes 35 ~ 55 parts of Lentinus Edodess 35 ~ 50 portions of Auricularias
Herba Urticae Cannabinae 25 ~ 45 portions of Fructus Crataegis 25 ~ 40 portions of Thallus Gracilariaes 20 ~ 40 portions of Germinatus Phragmitiss 20 ~ 35 parts.
3. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Sesami Nigrum 70 ~ 75 portions of Rhizoma Dioscoreaes 60 ~ 75 parts of Radix Puerariaes 60 ~ 70 parts of Amaranthus mangostanus L.s 55 ~ 70 parts
Semen Ginkgo 50 ~ 70 parts of Cortexs Eucommiae 50 ~ 65 parts of Radix Polygoni Multiflori 50 ~ 60 parts of Folium Evodiae trichotomae 45 ~ 60 parts
35 ~ 45 parts, Radix Salviae Miltiorrhizae 45 ~ 55 portions of Radix Dauci Sativaes 40 ~ 50 parts of Lentinus Edodess 40 ~ 45 portions of Auricularias
Herba Urticae Cannabinae 30 ~ 40 portions of Fructus Crataegis 30 ~ 35 portions of Thallus Gracilariaes 25 ~ 35 portions of Germinatus Phragmitiss 25 ~ 30 parts.
4. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Sesami Nigrum 72 portions of Rhizoma Dioscoreaes 67 parts of Radix Puerariaes 65 parts of Amaranthus mangostanus L.s 63 parts
Semen Ginkgo 60 parts of Cortexs Eucommiae 60 parts of Radix Polygoni Multiflori 55 parts of Folium Evodiae trichotomae 52 parts
40 parts, Radix Salviae Miltiorrhizae 50 portions of Radix Dauci Sativaes 45 parts of Lentinus Edodess 42 portions of Auricularias
Herba Urticae Cannabinae 35 portions of Fructus Crataegis 32 portions of Thallus Gracilariaes 30 portions of Germinatus Phragmitiss 28 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of cardiovascular and cerebrovascular disease, it is characterized in that: comprise following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density under 60 DEG C of environment is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, being condensed into relative density under 70 DEG C of environment is the thick paste of 1.20 ~ 1.25, for subsequent use;
(5) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the Chinese medicine preparation of described treatment cardiovascular and cerebrovascular disease.
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| JP2016529221A (en) | 2013-06-28 | 2016-09-23 | アントニー, ベニーANTONY, Benny | Medicinal composition derived from amaranth extract with concentrated nitrate content and method for preparing the same |
| US11338005B2 (en) | 2013-06-28 | 2022-05-24 | Arjuna Natural Private Limited | Medicinal composition of amaranth origin for cardiovascular treatment |
| CN108077538A (en) * | 2017-12-27 | 2018-05-29 | 孝感麻糖米酒有限责任公司 | A kind of sesame candy of lowering blood pressure and blood fat and preparation method thereof |
| CN108634238A (en) * | 2018-03-23 | 2018-10-12 | 贵州贵和隆科技研发有限公司 | A kind of alcohol-neutralize healthy product and preparation method thereof |
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| CN101623090A (en) * | 2008-07-08 | 2010-01-13 | 刘泳宏 | Colored blood fat, sugar and pressure reducing fruit and vegetable tea drink and preparation method thereof |
| CN101428110A (en) * | 2008-09-27 | 2009-05-13 | 钱修平 | Hypolipemic capsule of ginseng |
| CN102763800B (en) * | 2012-08-16 | 2013-12-11 | 梅晓芳 | Health care fruit and vegetable powder composed of antioxidative and cholesterol removal foods and drugs capable of benefiting vital energy, invigorating blood circulation and eliminating stasis |
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