CN103599360A - Traditional Chinese medicament for treating diabetic nephropathy - Google Patents

Abstract

The invention provides a medicament for treating diabetic nephropathy. The medicament is characterized by comprising the following components by weight: 10-20g of lily, 5-15g of plantain seed, 6-12g of glossy privet fruit, 6-12g of pseudo-ginseng, 5-15g of Chinese angelica, 10-20g of rehmannia, 6-12g of nostoc commune, 5-15g of semen euryales, 6-12g of pepper and the like. The medicament has the effects of tonifying qi and nourishing blood, activating blood circulation to remove stasis, dispelling dampness and promoting diuresis and the like.

Description

A kind of Chinese medicine for the treatment of of diabetic nephropathy

Technical field

The field of Chinese medicines that the invention belongs to treatment diseases of urinary system, specifically, relates to a kind of Chinese medicine for the treatment of of diabetic nephropathy.

Background technology

According to statistics, at present, in the nephrotic of China, approximately 52% is diabetic nephropathy, is a sizable illness colony.Diabetic nephropathy is, due to diabetes complicated glomerular microangiopathy becomes, to be one of lethal major reason of diabetes.Diabetics approximately 20% is died from this disease.Be intended at present the field of Chinese medicines for the treatment of of diabetic nephropathy, have the shortcoming of two aspects: the one, effect is obvious not; The 2nd, take effect slower, large quantities of diabetic nephropathy patient are owing to can not get the treatment of active drug, and nephropathy development, constantly worsens, and becomes renal failure, threat to life.Patient and family members are very dissatisfied.

Summary of the invention

For problem set forth above, the invention provides a kind of Chinese medicine for the treatment of of diabetic nephropathy, it can solve, and this type of Chinese medicine effect was obvious not in the past, the slower problem that takes effect, effective, instant effect, has drug effect definite, the advantage of quick result.

The present invention is achieved through the following technical solutions:

A medicine for treatment of diabetic nephropathy, is characterized in that, described medicine comprises following component:

Bulbus Lilii 10-20g, Herba Plantaginis 5-15g, Fructus Ligustri Lucidi 6-12g, Radix Notoginseng 6-12g, Radix Angelicae Sinensis 5-15g, Radix Rehmanniae 10-20g, ear 6-12g, Semen Euryales 5-15g, Radix orixae japonicae 6-12g, Rhizoma Dioscoreae 6-12g, Radix Puerariae 10-20g, Radix Ophiopogonis 5-15g, Herba Potentillae Discoloris 10-20g, Radix Astragali 10-20g, Rhizoma Coptidis 6-12g, Radix Trichosanthis 6-12g, winter folium mori 5-15g, Cortex Lycii 5-15g, Semen Cuscutae 6-12g, Rhizoma Polygonati 6-12g, Herba Epimedii 6-12g, Radix Glycyrrhizae 6-12g.

Preferably, described medicine comprises following component:

Bulbus Lilii 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, ear 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Rhizoma Dioscoreae 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.

Optionally, described medicine comprises following component:

Bulbus Lilii 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, ear 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Rhizoma Dioscoreae 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.

Optionally, described medicine comprises following component:

Bulbus Lilii 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, ear 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Rhizoma Dioscoreae 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.

The present invention is according to folk tradition formula, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling, develops meticulously.We think in research, and the most hypoimmunities of diabetics are raw in deficiency-heat, consume the body fluid that burns, blood is hypercoagulability, and stickiness is larger, and blood flow is slow, cause kidney blood supply insufficiency, nephridial tissue microcirculation is not smooth, and this is the basic reason of kidney of diabetic patients generation microangiopathies.So, with righting, attach most importance to, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, damp eliminating diuretic should be the rule for the treatment of of treatment of diabetic nephropathy.

The specific embodiment

Embodiment 1: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:

Bulbus Lilii 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, ear 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Rhizoma Dioscoreae 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.

Embodiment 2: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:

Bulbus Lilii 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, ear 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Rhizoma Dioscoreae 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.

Embodiment 3: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:

Bulbus Lilii 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, ear 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Rhizoma Dioscoreae 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.

In addition, above-described embodiment Chinese medicine manufacture method: weight in accordance with regulations, with conventional water extraction process, said medicine is extracted respectively, to make extract fine powder mixes, stir, make fine particle, pack capsule into No. 0, make Chinese medicinal capsule, every capsules includes 0.3 gram of Chinese medicine fine powder and extract.

Clinical data:

The present invention be take traditional Chinese medical science diabetic nephropathy as example, through 24 routine clinical observations.Selecting tcm diagnosis diabetic nephropathy is standard: diabetics has thirsty, polydipsia, frequent micturition, urgent micturition, spiritlessness and weakness, and edema of lower limbs, has albuminuria, serum creatinine (scr) 133～442 μ mol/L.As above symptom, can make a definite diagnosis.In making a definite diagnosis the object of observation, male's 12 examples, women's 12 examples, without other serious disease, the age is 42 years old-78 years old, 60.6 years old mean age.

Efficacy determination:

1, effective: body constitution strengthens, with it energetically; Polydipsia polyuria, urine urgency-frequency disappear; Edema of lower limbs is alleviated; Albuminuria obviously reduces, and serum creatinine declines more than 10%.

2, effective: polydipsia polyuria reduces to some extent, and with it energetically, edema, albuminuria are alleviated to some extent.

3, invalid: disease is unchanged.

During clinical experiment, withdraw other medicines and health nutrient.Taking the Chinese medicinal capsule that the specific embodiment of the invention 2 is made, observe 6 months, is a course for the treatment of.Instructions of taking: every day 2 times, each 4 capsules, every capsules includes 0.3 gram of Chinese medicine fine powder and extract, warm water delivery service after meal, after 1 month, symptom has alleviation, takes after 6 months, and symptom is obviously improved.In 24 people of clinical experiment, effective 11 people, effective 10 people, invalid 3 people, total effective rate 87.5%.

Claims (4)

1. a medicine for treatment of diabetic nephropathy, is characterized in that, described medicine comprises following component:

Bulbus Lilii 10-20g, Herba Plantaginis 5-15g, Fructus Ligustri Lucidi 6-12g, Radix Notoginseng 6-12g, Radix Angelicae Sinensis 5-15g, Radix Rehmanniae 10-20g, ear 6-12g, Semen Euryales 5-15g, Radix orixae japonicae 6-12g, Rhizoma Dioscoreae 6-12g, Radix Puerariae 10-20g, Radix Ophiopogonis 5-15g, Herba Potentillae Discoloris 10-20g, Radix Astragali 10-20g, Rhizoma Coptidis 6-12g, Radix Trichosanthis 6-12g, winter folium mori 5-15g, Cortex Lycii 5-15g, Semen Cuscutae 6-12g, Rhizoma Polygonati 6-12g, Herba Epimedii 6-12g, Radix Glycyrrhizae 6-12g.

2. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:

Bulbus Lilii 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, ear 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Rhizoma Dioscoreae 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.

3. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:

Bulbus Lilii 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, ear 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Rhizoma Dioscoreae 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.

4. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:

Bulbus Lilii 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, ear 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Rhizoma Dioscoreae 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.