The specific embodiment
The trophism of Chinese herbal feed additive is mainly reflected in and in Chinese herbal medicine, contains the necessary various nutriments of animal growth, as protein, amino acid, vitamin, trace element etc., thereby can promote diet nutrient full price, in Chinese herbal medicine, contain various active composition, there is sterilization, antibacterial effect, to Escherichia coli, yellow gold-coloured staphylococci, Diplococcus pneumopniae, streptococcus all has certain inhibitory action, polysaccharide in Chinese herbal medicine, alkaloid, organic acid volatilization wet goods has the immune effect of enhancing, Chinese herbal medicine can also improve collective defense resistance and regulate the sharp former effect that relaxes, body is regulated and improves physiological function, stop stress reaction, play anti-stress effect, natural Chinese medicinal herb itself does not contain vitamin ingredients, but play vitamin function, Chinese herbal medicine contains abundant bioactivator, can regulate the anti-disease physiological mechanism in body, improve the non-specific and specific immune function of livestock and poultry, strengthen on the whole the protection capability of body or there is immunologic enhancement.
The invention provides a kind ofly for improving the feed of growth performance of chicks, it comprises corn, wheat bran, the dish dregs of rice, albumen powder, galactomannan, VBT, soybean lecithin, Bee Pollen, salt, sodium bicarbonate, amino acid additive, vitamin(e) supplement, for improving Chinese herbal feed additive, trace mineral supplement and the microorganism formulation of growth performance of chicks.
In described feed, the weight portion of each material composition is respectively corn 80 weight portion~90 weight portions, wheat bran 8 weight portion~12 weight portions, the dish dregs of rice 8 weight portion~12 weight portions, albumen powder 1 weight portion~3 weight portion, galactomannan 2 weight portion~4 weight portions, VBT 1 weight portion~3 weight portion, soybean lecithin 3 weight portion~5 weight portions, Bee Pollen 2 weight portion~4 weight portions, salt 0.5 weight portion~1.5 weight portion, sodium bicarbonate 2 weight portion~4 weight portions, amino acid additive 4 weight portion~6 weight portions, vitamin(e) supplement 4 weight portion~6 weight portions, for improving Chinese herbal feed additive 10 weight portion~15 weight portions of growth performance of chicks, trace mineral supplement 2 weight portion~4 weight portions and microorganism formulation 2 weight portion~4 weight portions.
Further preferably, in described feed, the weight portion of each material composition is respectively corn 85 weight portions, wheat bran 10 weight portions, the dish dregs of rice 10 weight portions, albumen powder 2 weight portions, galactomannan 3 weight portions, VBT 2 weight portions, soybean lecithin 4 weight portions, Bee Pollen 3 weight portions, salt 1 weight portion, sodium bicarbonate 3 weight portions, amino acid additive 5 weight portions, vitamin(e) supplement 5 weight portions, for improving Chinese herbal feed additive 13 weight portions, trace mineral supplement 3 weight portions and microorganism formulation 3 weight portions of growth performance of chicks.
Galactomannans is a kind of biological species animal immunity regulator, has the animal intestinal of adjusting microorganism, improves animal autoimmunity ability, and prevention animal intestinal disease, improves fertility, improves price of deed power, improves the effect of meat.
VBT can promote growth, improves feed conversion rate, improves disease-resistant anti-stress ability, can reduce fat deposition, improves carcass lean meat percentage, improves meat, also can improve fecundity.
Soybean lecithin is the mixture of various phosphoglycerides and derivative thereof in soybean, it is the bioactivator with different physiological roles, mainly comprise lecithin, cephalin, phosphatidylinositols and serinephosphatide, soybean lecithin has the integrality of Cell protection membrane structure and function, anti-oxidant, reducing blood lipid, the effects such as regulation and control fat metabolism, can improve feed intake and the production performance of poultry, improve the health status of poultry, soybean lecithin adds in mixed feed can reduce the dust in mixed feed, thereby reduce the generation of livestock and birds respiratory disease, can prevent the automatic classification of dust from flying and feed, to keeping feed mixture homogeneity to there is good effect, the property balanced in nutrition that has kept daily ration, phosphatide has good lubricity, can reduce equipment attrition, reduce energy consumption simultaneously, and the temperature arrising caused by friction that makes feed reduces to minimum, phospholipid molecule has hydrophilic and two groups of oleophylic, therefore phosphatide is good fat emulsifier, can protect the unrighted acid in feed, improve the Quality and yield of granulating, can save the consumption of poultry to methionine, a large amount of liposoluble vitamins is provided, thereby can improve antioxidant levels fatty in feed.
Bee Pollen contains abundant amino acid, organized enzyme, vitamin, trace element and auxin etc., can supplement and balanced feed in essential nutritional labeling, be conducive to digesting and assimilating of body, promote growth, improve weightening finish, minimizing feedstuff-meat ratio.And that propolis contains corresponding glue source plant is similar, the concentrate of mass efficient active component, can accelerate the metabolic process of body, promotes growing of body.
Manna oligosaccharide can be controlled micro-ecological environment in intestines and stomach, promote the propagation of beneficial bacterium, suppress the field planting of harmful bacteria, thereby maintain normal stool road environment, there is the acceptor competitive adsorption with harmful bacteria, stop germ to be combined with animal intestinal epithelial cell, thereby accelerating bacterium discharges from enteron aisle, promote the effect of intestinal microecology balance, there is certain immunogenicity, can stimulate immune response reaction, and energy and some viruses, toxin and fungal cell's surface conjunction is as the adjuvant of these exogenous antigens, and then slow down the absorption of antigen, increase tiring of antigen, promote the glycoprotein of emiocytosis manna oligosaccharide base, these glycoprotein can be in conjunction with the bacterium of invading human body, trigger the multistage immunologic function of body, and strengthen the protection usefulness of flora, strengthen animal body fluid and cellular immunity.
Microorganism formulation, in the process of fermented feed, generates on the one hand carbohydrate, amino acids, a large number of nutrients such as protein-based, and it can directly increase the nutrition of cultivation body body; On the other hand, enter the dominant population that cultivation body enteron aisle forms useful viable bacteria, can improve the enteric microorganism ecosystem; Each beneficial bacterium can, by a series of biochemical reactions, produce physiological activator again under good condition.As various digestive ferments, metabolic enzyme, endocrine hormone etc., not only strengthen anti pathologic immunity ability, reduce disease, but also accelerate, to the digesting and assimilating of feed nutrient, to promote growth, put on weight, the price of deed improves.In addition, colony house stink alleviates, environmental sanitary quality improves, also be conducive to growing up healthy and sound of livestock, described microorganism formulation can be Lactobacillus casei, lactobacillus lactis, Lactobacillus plantarum, lactoenterococcus, Pediococcus pentosaceus, saccharomyces cerevisiae, candida utili, swamp Rhodopseudomonas, bacillus subtilis, one or more combine bacillus licheniformis, as source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides), this microorganism formulation primary raw material comprises product enzyme bacillus, lactic acid bacteria, saccharomycete, zytase, mannase, glucolase, amylase etc., effective viable bacteria content >=10,000,000,000/gram.
Trace mineral supplement can be the trace mineral supplement of various routines, can use simple acylate, as ironic citrate, also can use trace element and amino-acid chelate, as amino acid iron, the trace element adding mainly contains iron, zinc, copper, manganese, iodine, cobalt, selenium, molybdenum, also can use composite trace element premix, the Great Britain and America who provides as Beijing You Libao biotechnology Co., Ltd you.
Amino acid additive comprises the various conventional amino acid such as serine, glutamic acid, glycine, isoleucine, leucine, alanine, proline, also can adopt amino acid premix, the composite aminophenol powder that as above sea cowry energy Chemical Co., Ltd. produces.
Vitamin(e) supplement comprises the various conventional vitamins such as riboflavin, vitamin C, vitamin E, vitamin A, Cobastab, also can adopt vitamin premix, as plain in the excellent dimension that Beijing You Libao Bioisystech Co., Ltd produces.
Further preferably, described feed only consists of above-mentioned raw materials.
Chinese veterinarian thinks, The spleen and stomach provide the material basis of the acquired, main muscle and four limbs, be source of generating QI and blood, defeated cloth diet precise and tiny, with nutrition the five internal organs six abdomen four limbs boness of the body collectively, therefore temper is strong transports, diet multiplication, and healthy tendency is from filling, nutritional sufficiency, fleshiness is strong, otherwise the contracting of muscle committee, carcass is become thin, therefore, Chinese herbal feed additive provided by the invention is to using the theory of Chinese veterinarian's theory of spleen and stomach as guiding theory, by Chinese herbal medicine to reach strengthening the spleen and stomach, aid digestion, thus the feed intake of chick improved, the object that promotion utilizes absorption of nutrient ingredients, short to solve chick alimentary canal, the drawback low to efficiency of feed utilization, the bulk drug that described Chinese herbal feed additive comprises has the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon.
Further, described Chinese herbal feed additive only consists of above-mentioned raw materials medicine.
The pharmacology of described each bulk drug is as follows:
The bighead atractylodes rhizome: taste is sweet, bitter, warm in nature, enters spleen, stomach warp, has tonifying spleen profit gas, eliminating dampness Li Shui, and strengthening exterior and reducing sweat, the effect that fortune spleen is moisturized, is mainly used in ruffian due to the dysfunction of the spleen in transport, QI failing to transform into body fluid and has one's mind filled with and rush down, phlegm and retained fluid oedema; The vexed lazy speech of the deficiency of qi in middle-jiao, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, abnormal sweating spontaneous perspiration.
Spina date seed: taste is sweet, sour, property is flat, has nourishing conscience, calms the nerves, and the effect of arrest sweating, cures mainly restlessness of asrhenia type and insomnia; Palpitation with fear palpitation; The cards such as the empty spontaneous perspiration of body, night sweat.
Mantis egg-case: latin name Ootheca Mantidis, become sweet, flat, return liver, kidney, urinary bladder channel, there is kidney tonifying, astringent or styptic treatment for spontaneous sweating, the effect of only losing, cure mainly the cards such as infantile enuresis, frequent urination at night, seminal emission premature ejaculation, impotence of the insufficiency of the kidney yang, not only help but also inducing astrigency, be tonify the kidney and support yang, the good medicine of controlling nocturnal emission with astringent drugs contracting urine.Emission and spermatorrhea, the enuresis, frequent micturition, impotence due to all kidney yang deficiencies, vital essence mistake are admittedly sterile, all can select the especially suitable enuresis, frequent micturition.
The vine of multiflower knotweed: sweet, the micro-hardship of taste, property is flat; The thoughts of returning home, Liver Channel, having can mental-tranquilization, the effect of dispelling wind and removing obstruction in the meridians, cures mainly insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, the cards such as wind sore mange.
Changshan: latin name Dichroae Radix, bitter, pungent, cold in nature, return lung, liver, the heart channel of Hang-Shaoyin, there is the effect of vomiting phlegmatic savliva, cure mainly phlegm and retained fluid and stop gathering, the cards such as chest diaphragm ruffian plug.
Hawthorn: taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of fall apart, is mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn is the staple for the treatment of indigestion, hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc. are had to obvious inhibitory action.
Saline cistanche: taste is sweet, one-tenth, warm in nature, enters kidney, and large intestine channel, has kidney-replenishing, benefiting essence-blood, the effect relaxing bowel, for decline of kidney-YANG, the impotence and premature ejaculation of asthenia of essence and blood, infertile, soreness of waist and knee joint, Hiccough and deaf, frequent micturition urine number, the intestines of the suffering from a deficiency of the kidney deficiency of blood in dry and postpartum, the cards such as constipation that body fluid deficiency after being ill.
Radix pseudostellariae: sweet, the micro-hardship of taste, property is put down, and enters spleen, lung channel, has air making-up and spleen enlivening, the effect that moistening lung is promoted the production of body fluid, for the few burnout of food of deficiency-weakness of spleen-QI, deficiency of stomach-Yin, the beneficial temper of energy, nourishing stomach-YIN, many for the deficiency syndrome of the lung cough caused by dryness of deficiency of vital energy Tianjin wound and palpitaition egersis, abnormal heat sweat, energy nourishing generate fluid, controls deficiency of vital energy xeropulmonary cough, the cards such as the palpitaition egersis of deficiency of both qi and yin, hidrosis.
Folium panacis japonici cum caule: bitter, sweet, cold in nature, attach to the lung and stomach meridians, there is tonifying Qi, beneficial lung, drives away summer heat, and the effect of promoting the production of body fluid, cures mainly qi-asthenia cough, and hot summer weather is irritated, and Tianjin wound is thirsty, and the head is unclear, the tired weary card that waits of four limbs.
Wilsonii: latin name Acanthopanacis Senticosi Radix etRhizoma seu Caulis, taste is pungent, bitter, micro-sweet, warm in nature, enter spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is frail, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
Chinese yam: taste is sweet, property is put down, enter lung, spleen, kidney channel, have strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, the effect that helps the five internal organs, strengthening the bones and muscles, long will to calm the nerves, promote longevity, cure mainly that weakness of the spleen and the stomach, lassitude, poor appetite, chronic diarrhea and dysentery, Lung Qi deficiency are dry, asthma due to excessive phlegm cough, kidney qi loss, soreness and weakness of waist and knees, lower limb impotence are weak, the red card such as swollen, fat of gonorrhoea under the frequent micturition of quenching one's thirst, seminal emission premature ejaculation, band, skin.
The rhizome of davallia: bitter, warm in nature, enter liver, kidney channel, there is nourishing disney and strengthening bone, continuous effect of hindering pain relieving, for the soreness of waist and knee joint of suffering from a deficiency of the kidney, flaccidity and weakness of the lower limbs, the deficiency of liver-yin and kidney-yin, empty positive rising and the deafness and tinnitus that causes, tooth mobility pain or bleeding gums, speen-kidney dificiency and cause and rush down for a long time the cards such as protracted dysentery.
The stem of noble dendrobium: cold nature, taste is sweet, returns stomach, kidney channel, has reinforcing stomach reg fluid, nourishing Yin and clearing heat effect.Cure mainly the moon and hinder body fluid deficiency, dry polydipsia, food is few retches, abnormal heat after being ill, order is the not clear card that waits secretly.
The fruit of glossy privet: taste is sweet, bitter, is slightly cold, enters liver, kidney channel, has strong liver kidney-nourishing, and the effect of removing heat to brighten vision, is mainly used in treating liver-kidney Yin deficiency, and the head loses foster dizzy tinnitus, the symptoms such as yin asthenia generating intrinsic heat.The fruit of glossy privet can promote leucocyte, strengthens the effect of immunologic function, and staphylococcus aureus, shigella dysenteriae are had to stronger inhibitory action.
Asparagus fern: taste is sweet, bitter, cold in nature, returns lung, kidney channel, has nourishing yin to moisten dryness, the effect that clearing lung-heat is promoted the production of body fluid, cures mainly cough caused by dryness-heat, and deficiency of Yin labor is coughed, fire excess from yin deficiency, the abscess of throat of seminal emission, premature ejaculation and flaring up of deficient fire that kidney essense is not solid, pyreticosis Tianjin wound is thirsty, the interior heat cards such as the dry constipation of intestines of quenching one's thirst.
Honeysuckle: taste is sweet, cold in nature, enters the heart, lung, stomach, large intestine channel, has clearing heat and detoxicating effect, double can removing heat from the blood and relieve diarrhea.Be mainly used in affection of exogenous wind-heat, the hot poison of warm heat disease is contained, or warm disease is from the beginning of heat evil still at the part of the body cavity above the diaphragm housing the heart and lungs and when not descending; The malicious diarrhea of heat, the lower blood of stool; Heat temperature card; The sore carbuncle that hot poison gathers from the beginning of, lift the heat person of swelling and ache etc., honeysuckle has good antipyretic effect, energy anti-inflammatory, what control inflammation oozes out and inflammatory hyperplasia, can promote leukocytic phagocytic function, multiple pyococcus and pathogenic entero becteria are had to stronger bacteriostasis, comprise staphylococcus, hemolytic streptococcus, diplococcus meningitidis, shigella dysenteriae, typhoid bacillus, Pseudomonas aeruginosa, tubercle bacillus etc., the hot poison that honeysuckle is divided qi and blood battalion is all effective, and has broad-spectrum antibacterial action.
The fruit of Chinese wolfberry: taste is sweet, property is flat, enters liver, kidney channel, have tonify the liver and kidney, nourish blood enrich blood, benefiting shrewd head, the effect that moistens the lung and relieve the cough, be mainly used in soreness and weakness of waist and knees, dizziness and tinnitus, seminal emission tinnitus, the unconsciously sweat and tire of liver kidney two void, asthenia of essence and blood; The impotence of the insufficiency of the kidney yang, sterile; Dim-sighted and the deficiency of Yin labor of the eyes of deficiency of YIN-essence,impairment of YIN-essence, the deficiency of liver-blood card such as cough, the fruit of Chinese wolfberry can promote liver cell regeneration, strengthens the effect of non-specific immune function.
Hairyvein agrimony: latin name Agrimoniae Herba, bitter, puckery, property is flat, the thoughts of returning home, Liver Channel, have astringing to arrest bleeding, only the effect of dysentery desinsection, cures mainly various hemorrhage cards, for example: haematemesis, hematuria, have blood in stool, uterine bleeding, spitting of blood, bleeding from five sense organs or subcutaneous tissue, dysentery, internal lesion caused by overexertion takes off power, and carbuncle is swollen, fall and beat, the cards such as traumatic bleeding.
The root of herbaceous peony: latin name Paeoniae RadixAlba, bitter, acid, cool in nature; enter liver, the spleen channel, there is nourishing blood and liver, slow middle pain relieving; astringe yin is received the effect of sweat, cures mainly chest abdomen pain over the hypochondriac region, rushes down dysentery stomachache; spontaneous sweating; fever due to yin deficiency, irregular menstruation, uterine bleeding; be with inferior card, the root of herbaceous peony has good liver-protective effect.
Rhizoma zingiberis: taste is pungent, hot in nature, return spleen, stomach, the heart, lung channel; Have warming spleen and stomach for dispelling cold, Hui Yang promotes blood circulation, eliminating dampness dissolving phlegm, and the effect of warming lung to reduce watery phlegm, for coldness and pain in the epigastrium, vomiting, has loose bowels, and yang depletion is fainted contrary, and cold drink is breathed with cough, the cards such as numbness and ache of cold dampness.
Mistletoe: bitter, sweet, property is flat, returns liver, kidney channel, has filling liver kidney, strengthening the bones and muscles, wines used as antirheumatic, antiabortive effect, cures mainly soreness of waist and knee joint; Arthralgia due to wind-dampness; Fetal irritability; The card such as blood under threatened abortion.
The coptis: bitter, cold in nature, enter the heart, lung, courage, stomach, large intestine channel, there is heat-clearing and damp-drying drug, purging intense heat and detonicating, the effect of cooling blood for improving eyesight, is usually used in treating the fire of removing the heart-fire warp, the dysphoria and insomnia that internal heat is prosperous, and the high fever coma of warm heat disease, the card such as vexed, thirsty.
Great burdock achene: taste is pungent, hardship; Cold in nature, return lung, stomach warp, has dispelling wind and heat from the body, clearing heat and detoxicating promoting eruption, the loose swollen effect of a surname's lung relieve sore throat, cure mainly anemopyretic cold, warm disease from the beginning of; Wind-heat or cough with lung heat, cough up phlegm not smooth; Abscess of throat; Macula is not saturating; At the measles initial stage, rash goes out not smooth and rubella itch; The card such as sore swollen toxin and mumps.
Cassia twig: taste is pungent, sweet, warm in nature, the thoughts of returning home, lung, urinary bladder channel, have sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, the effect of eliminating cold to stop pain, cassia twig warming meridians and promoting circulation of qi, horizontal logical podomere, for the illness that has not attacked the vital organs of the human body of catching cold, no matter have sweat, losslessly all can apply, also for arthralgia due to wind-dampness, stomach cold stomachache, through closing, dysmenorrhoea, arthralgia due to wind-dampness, the cards such as shoulder arm podomere crymodynia.
Radix Isatidis: latin name Isatidis Radix, bitter, cold in nature, enters the heart, liver, courage, stomach warp, has the effect of clearing heat and detoxicating, cool blood relieve sore throat, is used for the treatment of febrile virulent maculae; High heat headache; Major part pestilence; Tongue is dark reddish purple dark, scarlet fever; Erysipelas; Mumps; Larynx numbness; Sore is swollen, carbuncle is swollen; Varicella; Measles; Hepatitis; Influenza, epidemic meningitis, encephalitis, pneumonia, coma is told nosebleed, and pharynx is swollen, pinkeye, sore rash; Can prevent and treat the cards such as Japanese Type-B encephalitis, acute, chronic hepatitis, mumps, osteomyelitis, Radix Isatidis has inhibitory action to various bacteria. and infusion has inhibitory action in various degree to hay bacillus, staphylococcus aureus, sarcine, Escherichia coli, typhoid bacillus, paratyphosum Bacterium, dysentery (will he, Fu Shi) bacillus, bacillus enteritidis etc.
Pilose gerbera herb: bitter, pungent, property is flat, has the cough-relieving of a surname's lung, clearing heat and detoxicating, dampness removing, the effect of the promoting flow of qi and blood circulation, cures mainly cough due to common cold, and asthma is had loose bowels, dysentery, oedema, stranguria with turbid discharge, epigastric distending pain, treating swelling and pain by traumatic injury, the cards such as venomous snake bite.
Virgin's milk mushroom: bitter, pungent, warm in nature, there is expelling wind and clearing away cold, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, cures mainly lumbocrural pain, numb in every limb, and muscles and bones is not relaxed, the cards such as tic of limbs.
Fokien angiopteris rhizome: mildly bitter flavor, cool in nature, there is the effect of heat-clearing, cool blood, removing toxic substances, cure mainly treating swelling and pain by traumatic injury, traumatism and bleeding, uterine bleeding, acute mastitis, the carbuncle furunculosis that swells, arthralgia due to wind-dampness, postpartum abdominal pain, vexed insomnia, the cards such as venomous snake bite.
Water bean cotyledon: taste is sweet, light, cool in nature, has clearing heat and promoting diuresis, the effect of subdhing swelling and detoxicating, cures mainly dysentery, gonorrhoea, oxyhepatitis, carbuncle sore tumefacting virus, swelling and aching of gum, acute mastitis, acute cerebral meningitis, acute laryngopharyngitis, irregular menstruation, dysmenorrhoea, the cards such as burn and scald.
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 35 weight portion~45 weight portions, spina date seed 20 weight portion~30 weight portions, mantis egg-case 25 weight portion~35 weight portions, the vine of multiflower knotweed 30 weight portion~40 weight portions, Changshan 15 weight portion~25 weight portions, hawthorn 30 weight portion~40 weight portions, saline cistanche 35 weight portion~45 weight portions, radix pseudostellariae 40 weight portion~50 weight portions, folium panacis japonici cum caule's 30 weight portion~40 weight portions, wilsonii 25 weight portion~35 weight portions, Chinese yam 30 weight portion~40 weight portions, the rhizome of davallia 20 weight portion~30 weight portions, the stem of noble dendrobium 35 weight portion~45 weight portions, the fruit of glossy privet 25 weight portion~35 weight portions, asparagus fern 20 weight portion~30 weight portions, honeysuckle 45 weight portion~55 weight portions, the fruit of Chinese wolfberry 30 weight portion~40 weight portions, hairyvein agrimony 20 weight portion~30 weight portions, the root of herbaceous peony 35 weight portion~45 weight portions, rhizoma zingiberis 15 weight portion~25 weight portions, mistletoe 25 weight portion~35 weight portions, the coptis 55 weight portion~65 weight portions, great burdock achene 20 weight portion~30 weight portions, cassia twig 25 weight portion~35 weight portions, Radix Isatidis 45 weight portion~55 weight portions, pilose gerbera herb 35 weight portion~45 weight portions, Virgin's milk mushroom 20 weight portion~30 weight portions, fokien angiopteris rhizome 25 weight portion~35 weight portions and water bean cotyledon 30 weight portion~40 weight portions.
Further preferably, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 38 weight portion~42 weight portions, spina date seed 23 weight portion~27 weight portions, mantis egg-case 28 weight portion~32 weight portions, the vine of multiflower knotweed 33 weight portion~37 weight portions, Changshan 18 weight portion~22 weight portions, hawthorn 33 weight portion~37 weight portions, saline cistanche 38 weight portion~42 weight portions, radix pseudostellariae 43 weight portion~47 weight portions, folium panacis japonici cum caule's 33 weight portion~37 weight portions, wilsonii 28 weight portion~32 weight portions, Chinese yam 33 weight portion~37 weight portions, the rhizome of davallia 23 weight portion~27 weight portions, the stem of noble dendrobium 38 weight portion~42 weight portions, the fruit of glossy privet 28 weight portion~32 weight portions, asparagus fern 23 weight portion~27 weight portions, honeysuckle 48 weight portion~52 weight portions, the fruit of Chinese wolfberry 33 weight portion~37 weight portions, hairyvein agrimony 23 weight portion~27 weight portions, the root of herbaceous peony 38 weight portion~42 weight portions, rhizoma zingiberis 18 weight portion~22 weight portions, mistletoe 28 weight portion~32 weight portions, the coptis 58 weight portion~62 weight portions, great burdock achene 23 weight portion~27 weight portions, cassia twig 28 weight portion~32 weight portions, Radix Isatidis 48 weight portion~52 weight portions, pilose gerbera herb 38 weight portion~42 weight portions, Virgin's milk mushroom 23 weight portion~27 weight portions, fokien angiopteris rhizome 28 weight portion~32 weight portions and water bean cotyledon 33 weight portion~37 weight portions.
Further preferred, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 40 weight portions, spina date seed 25 weight portions, mantis egg-case 30 weight portions, the vine of multiflower knotweed 35 weight portions, Changshan 20 weight portions, hawthorn 35 weight portions, saline cistanche 40 weight portions, radix pseudostellariae 45 weight portions, folium panacis japonici cum caule's 35 weight portions, wilsonii 30 weight portions, Chinese yam 35 weight portions, the rhizome of davallia 25 weight portions, the stem of noble dendrobium 40 weight portions, the fruit of glossy privet 30 weight portions, asparagus fern 25 weight portions, honeysuckle 50 weight portions, the fruit of Chinese wolfberry 35 weight portions, hairyvein agrimony 25 weight portions, the root of herbaceous peony 40 weight portions, rhizoma zingiberis 20 weight portions, mistletoe 30 weight portions, the coptis 60 weight portions, great burdock achene 25 weight portions, cassia twig 30 weight portions, Radix Isatidis 50 weight portions, pilose gerbera herb 40 weight portions, Virgin's milk mushroom 25 weight portions, fokien angiopteris rhizome 30 weight portions and water bean cotyledon 35 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtain mixture, put into reactor, add the water with respect to 3~5 times of mixture qualities, slow fire heating decocts 2~4 hours, and decoction liquor is filtered, filter residue adds the water with respect to 2~4 times of the mixture qualities obtaining above, and slow fire boiling is 1~3 hour again, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
The present invention also provides the preparation method of above-mentioned feed, and it comprises:
The first step, getting 3kg microbe additive joins in 50kg~100kg water and mixes, obtain zymotic fluid, 85kg corn, 10kg wheat bran, the 10kg dish dregs of rice are mixed, obtain mixture, get the zymotic fluid that 100kg obtains above and join in the mixture obtaining above, evenly pack sealing, is placed in the environment of 20 ℃~30 ℃ and obtains fermentation material after 10~20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
The 3rd step, together with the Chinese herbal feed additive that the fermentation material that the first step is obtained obtains with second step and other components, put into fodder mixing machine, continuous uniform stirred after 1~3 hour, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, the feed that gets product after sterilization, sealing, pack of the fine grained after pulverizing.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition feed addictive 1
By bighead atractylodes rhizome 40g, spina date seed 25g, mantis egg-case 30g, vine of multiflower knotweed 35g, Changshan 20g, hawthorn 35g, saline cistanche 40g, radix pseudostellariae 45g, folium panacis japonici cum caule 35g, wilsonii 30g, Chinese yam 35g, rhizome of davallia 25g, stem of noble dendrobium 40g, fruit of glossy privet 30g, asparagus fern 25g, honeysuckle 50g, fruit of Chinese wolfberry 35g, hairyvein agrimony 25g, root of herbaceous peony 40g, rhizoma zingiberis 20g, mistletoe 30g, coptis 60g, great burdock achene 25g, cassia twig 30g, Radix Isatidis 50g, pilose gerbera herb 40g, Virgin's milk mushroom 25g, fokien angiopteris rhizome 30g and water bean cotyledon 35g mix, obtain mixture, put into reactor, the water that adds 4kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 3kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 1.
Embodiment 2 Chinese medicine composition feed addictives 2
By bighead atractylodes rhizome 38g, spina date seed 23g, mantis egg-case 28g, vine of multiflower knotweed 33g, Changshan 18g, hawthorn 33g, saline cistanche 38g, radix pseudostellariae 43g, folium panacis japonici cum caule 33g, wilsonii 28g, Chinese yam 33g, rhizome of davallia 23g, stem of noble dendrobium 38g, fruit of glossy privet 28g, asparagus fern 23g, honeysuckle 48g, fruit of Chinese wolfberry 33g, hairyvein agrimony 23g, root of herbaceous peony 38g, rhizoma zingiberis 18g, mistletoe 28g, coptis 58g, great burdock achene 23g, cassia twig 28g, Radix Isatidis 48g, pilose gerbera herb 38g, Virgin's milk mushroom 23g, fokien angiopteris rhizome 28g and water bean cotyledon 33g mix, obtain mixture, put into reactor, the water that adds 3.5kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 2.5kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 2.
Embodiment 3 Chinese medicine composition feed addictives 3
By bighead atractylodes rhizome 42g, spina date seed 27g, mantis egg-case 32g, vine of multiflower knotweed 37g, Changshan 22g, hawthorn 37g, saline cistanche 42g, radix pseudostellariae 47g, folium panacis japonici cum caule 37g, wilsonii 32g, Chinese yam 37g, rhizome of davallia 27g, stem of noble dendrobium 42g, fruit of glossy privet 32g, asparagus fern 27g, honeysuckle 52g, fruit of Chinese wolfberry 37g, hairyvein agrimony 27g, root of herbaceous peony 42g, rhizoma zingiberis 22g, mistletoe 32g, coptis 62g, great burdock achene 27g, cassia twig 32g, Radix Isatidis 52g, pilose gerbera herb 42g, Virgin's milk mushroom 27g, fokien angiopteris rhizome 32g and water bean cotyledon 37g mix, obtain mixture, put into reactor, the water that adds 4kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 3kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 3.
Embodiment 4 pharmacology toxicity tests
Acute toxicity test data
Detect reagent
Serum AST, ALT detection kit are purchased from Rui Sheng bio tech ltd, Qingdao.
Checkout equipment
Micro-200 semiautomatic biochemistry detector, assay balance, disscting instrument, syringe, test tube etc.
Test method
After the adaptability of 3 days are raised, be divided at random 4 groups (male and female half and half), every group each 20; Control group, 3 different pharmaceutical groups (are respectively 300g/kg body weight, 240g/kg body weight, 180g/kg body weight), control group gavage physiological saline, the Chinese herbal feed additives 1 of 3 medicine group gavage embodiment of the present invention, 1 preparation, are dissolved in Chinese herbal feed additive in water, to gavage mouse.
Testing index and method
(1) clinicing symptom observation: every day viewing test mouse the state of mind, diet situation, every day entry Mortality situation.
(2) pathological observation: cut open inspection for dead mouse and observe internal organ variation.
(3) growth indexes is observed: test mouse is carried out to routine weighing; Off-test, slaughters that mouse weighs in, the heavy organ index of internal organs measures: cut open inspection rat, dirty, the spleen of coring, liver, kidney, testis, ovary, weigh, and calculates according to the following formula organ index: organ index=internal organs weight/body weight * 100.
(4) liver function changes observation: after off-test, slaughter mouse, take blood separation of serum, measure AST, ALT.
Data processing and analysis
Each is organized data and all uses mean soil standard deviation
represent, each is organized mean and does test of normality and duplicate measurements homogeneity test of variance, younger check between organizing with one-way analysis of variance), P < 0.05 is for differing significantly, and P < 0.01 is for differing highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Clinicing symptom observation
Control group and test group mouse, the state of mind and diet are wanted, respond has no significantly abnormal to external world.Each organizes mouse morbidity and death condition as following table 1.
Table 1
Grouping |
Sum |
Dead (only) |
The death rate (%) |
1(300g/kg) |
20 |
0 |
0 |
2(240g/kg) |
20 |
0 |
0 |
3(120g/kg) |
20 |
0 |
0 |
Control group |
20 |
0 |
0 |
Pathological observation: control group and test group, mouse is cutd open after slaughtering to examine to observe to have no and observes the obvious pathological change of internal organs.
Growth indexes is observed: off-test, slaughter that mouse weighs in, internal organs weight analysis is in Table 2.
Table 2
Grouping |
Liver index |
Cardiac index |
Renal index |
Lungs index |
Index and spleen index |
1(300g/kg) |
5.83±0.26 |
0.76±0.05 |
1.29±0.21 |
0.63±0.02 |
0.52±0.03 |
2(240g/kg) |
5.79±0.31 |
0.78±0.03 |
1.27±0.16 |
0.67±0.06 |
0.53±0.05 |
3(120g/kg) |
5.80±0.22 |
0.72±0.07 |
1.23±0.13 |
0.69±0.03 |
0.49±0.03 |
Control group |
5.70±0.31 |
0.79±0.06 |
1.30±0.17 |
0.69±0.11 |
0.53±0.07 |
Liver function changes to be observed
After off-test, slaughter mouse, take blood separation of serum, measure AST (glutamic-oxalacetic transaminease), ALT (glutamic-pyruvic transaminase) in Table 3.Result shows respectively to be organized data and normal healthy controls group to compare difference not remarkable, all in normal range (NR).
Table 3
Grouping |
Sum |
ALT |
AST |
1(300g/kg) |
20 |
34.16±2.53 |
131.73±13.91 |
2(240g/kg) |
20 |
33.29±2.62 |
133.21±10.75 |
3(120g/kg) |
20 |
33.73±2.59 |
132.63±9.38 |
Control group |
20 |
35.11±3.26 |
131.26±14.11 |
Long term toxicity test data
According to the Chinese herbal feed additive 10g/kg of the present invention of embodiment 1 preparation, 20g/kg, 100g/kg to the continuous gastric infusion of rat 3 months, the fur of animal, the colour of skin, ingest, movable, urine, just etc. all without the main organs index of the blood parameters such as the routine blood test of animal extremely, liver, renal function and animal all in normal range (NR), and normally power indifference histopathologic examination shows, the important organs such as the heart, liver, spleen, lung, kidney, adrenal gland, tracheae, testis, ovary are without pathological change.Drug withdrawal checks after two weeks that above indices, all without overt toxicity reaction, shows without cumulative toxicity.
Embodiment 5 feeds 1
Getting 3kg microbe additive source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) joins in 100kg water and mixes, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins corn 85kg, wheat bran 10kg, in the main feed composition that dish dregs of rice 10kg forms, evenly pack sealing, be placed in the environment of 25 ℃ and obtain fermentation material after 15 days, by Chinese herbal feed additive 13kg and galactomannan (rural area, the Zhengzhou food science and technology Co., Ltd provides) 3kg of the fermentation material obtaining and embodiment 1 acquisition, VBT (Zhengzhou Cheng Wang chemical industry Co., Ltd provides) 2kg, soybean lecithin (source, Beijing magnificent phosphatide Science and Technology Ltd. provides) 4kg, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 3kg, salt 1kg, sodium bicarbonate 3kg, amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamin(e) supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, you put into fodder mixing machine by (Beijing You Libao biotechnology Co., Ltd provides) 3kg together trace mineral supplement Great Britain and America, continuous uniform stirred after 3 hours, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, fine grained after pulverizing is through sterilization, sealing, feed 1 gets product after pack.
Comparative example
Getting 3kg microbe additive source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) joins in 100kg water and mixes, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins corn 85kg, wheat bran 10kg, in the main feed composition that dish dregs of rice 10kg forms, evenly pack sealing, be placed in the environment of 25 ℃ and obtain fermentation material after 15 days, by the fermentation material and galactomannan (rural area, the Zhengzhou food science and technology Co., Ltd provides) 3kg that obtain, VBT (Zhengzhou Cheng Wang chemical industry Co., Ltd provides) 2kg, soybean lecithin (source, Beijing magnificent phosphatide Science and Technology Ltd. provides) 4kg, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 3kg, salt 1kg, sodium bicarbonate 3kg, amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamin(e) supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, you put into fodder mixing machine by (Beijing You Libao biotechnology Co., Ltd provides) 3kg together trace mineral supplement Great Britain and America, continuous uniform stirred after 3 hours, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, fine grained after pulverizing is through sterilization, sealing, feed 2 gets product after pack.
Embodiment 6 effect datas
Test feed
Test group adopts the feed 1 of embodiment 5 preparations, the feed 2 that control group adopts comparative example to be prepared into.
Experimental animal and feeding and management
800 of healthy 1 age in days AA chick are selected in test, are divided into test group and control group, every group of 4 repetitions, and each repeats 100 chickens, the feed 1 of test group feeding embodiment 5 preparations, the feed 2 that control group feeding comparative example is prepared into, experimental period is 48 days.
Feeding and management
Test chicken is flat supporting on the net, and each is organized the every 15d of Ji Zunei recurrence interval, interval fence and adjusts 1 time, and regularly feeding, freely drinks water, and regularly vaccine injection, adopts four groups of fans to give up interior ventilation, and hen house ight soil is disposable removing when delivering for sale.Control group adds antibiotics chemicals in right amount according to production actual conditions, or drinks water or sneak into feed and take; Test group chicken does not adopt antibiotics chemicals to carry out prevention from suffering from the diseases.
Each organizes the feed feed intake day before yesterday of weighing before 6:30 every day, weekly the 1st day early 7:00 carry out empty stomach and weigh.In experimental period, conscientiously observe chicken public sentiment condition, dead chicken number and the medicining condition washed in a pan of record.After off-test, every group of chicken randomly drawed 10, puts in isolated column, carries out slaughter determining on an empty stomach after 24h.
Observation index
Production performance index
Body weight index: early carry out measured body weight to organizing interior all chickens before 7:00 on the 1st day weekly in experimental period, take g as body weight measurement unit.
Feed daily ingestion amount index: early 7:00 respectively organized the chicken feed total amount of searching for food to front 1d before not feeding intake and weighed every day, take kg as daily ingestion amount measurement unit.
Death condition index
Every day early the dead quantity of chicken in record group before 6:30, cut open inspection pathology or the cause of disease.
Slaughter index
Carcass weight
Jugular vein bloodletting is butchered, and wet method is pulled out plumage, the carcass weight=live body weight-blood weight-feather g of Chong, unit.
Half clean thorax weight
Open abdomen and remove internal organ (comprise esophagus, the capsule of tremnbling, tracheae, reproductive system and digestive system), stay the weight after kidney, lung, heart, liver (removing courage) and muscular stomach (removing inclusion cutin membrane), the g of unit.
Complete clean thorax weight
Half clean thorax is heavily removed the body weight after head, pin, heart, liver, muscular stomach, the g of unit.
Abdomen fat weight
Weigh around trunk belly leaf fat, muscular stomach and the fatty g of Chong, unit at nearly anus place.
Data processing and analysis
Each is organized data and all uses mean soil standard deviation
represent, each is organized mean and does test of normality and duplicate measurements homogeneity test of variance, younger check between organizing with one-way analysis of variance), P < 0.05 is for differing significantly, and P < 0.01 is for differing highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Result
The impact of Chinese herbal feed additive on chick production performance, the results are shown in Table 4.
The impact of table 4 Chinese herbal feed additive on chick production performance
Time |
Index |
Test group |
Control group |
? |
Weightening finish in phase |
329.00±3.24 |
327.91±1.50 |
1~14 age in days |
Feed intake in phase |
529.03±4.93 |
536.43±5.61 |
? |
Material anharmonic ratio |
1.61∶1 |
1.64∶1 |
? |
Weightening finish in phase |
1351.39±13.39 |
1267.88±18.35 |
15~35 ages in days |
Feed intake in phase |
2601.49±14.06 |
2602.65±12.87 |
? |
Material anharmonic ratio |
1.93∶1 |
2.05∶1 |
? |
Weightening finish in phase |
1275.10±27.93 |
1258.87±26.23 |
36~48 ages in days |
Feed intake in phase |
2726.73±21.57 |
2779.20±28.61 |
? |
Material anharmonic ratio |
2.14∶1 |
2.21∶1 |
? |
Weightening finish in phase |
2955.49±33.75 |
2854.67±39.33 |
1~48 age in days |
Feed intake in phase |
5857.25±26.29 |
5918.29±28.19 |
? |
Material anharmonic ratio |
1.98∶1 |
2.07∶1 |
From table 4 result of the test, test group weightening finish is higher than control group (P < 0.05), test group is than the many weightening finishes of control group 100.82g, improve 3.53%, test group feed intake reduces 61.04g than control group, significant difference, P < 0.05, from material anharmonic ratio index, test group reduces by 4.35% than control group.
The impact of Chinese herbal feed additive on the chick death rate, the results are shown in Table 5.
The impact of table 5 Chinese herbal feed additive on the chick death rate
? |
Control group |
Test group |
First week |
0.25% (1 plumage) |
0.25% (1 plumage) |
Second week |
1.00% (4 plumage) |
0.25% (1 plumage) |
The 3rd week |
0.50% (2 plumage) |
0.00% (0 plumage) |
4th week |
1.00% (4 plumage) |
0.75% (3 plumage) |
The 5th week |
1.75% (7 plumage) |
1.25% (5 plumage) |
The 6th week |
1.50% (6 plumage) |
0.75% (3 plumage) |
The 7th week |
1.75% (7 plumage) |
1.00% (4 plumage) |
The full phase |
7.75% (31 plumage) |
4.25% (17 plumage) |
As can be seen from Table 5, adopt the chick death rate of Chinese herbal feed additive provided by the invention significantly lower than control group.
Chinese herbal feed additive, to the comparison of chick Slaughter, the results are shown in Table 6.
Table 6 Chinese herbal feed additive is to the comparison of chick Slaughter
Project |
Control group |
Test group |
Complete clean thorax dressing percentage |
67.13±0.91 |
70.13±0.77 |
Half clean thorax dressing percentage |
81.42±1.14 |
83.05±2.11 |
Abdomen fat rate |
1.92±0.23 |
1.77±0.08 |
As can be seen from Table 6, adopt the Slaughter of the chick of Chinese herbal feed additive of the present invention to be significantly better than control group, P < 0.05.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.