CN103566226B - 一种治疗化脓性肺炎的中药 - Google Patents
一种治疗化脓性肺炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗化脓性肺炎的中药，它是由以下重量配比的原料药材制备而成：鹅不食草4份、白及4份、茵陈5份、瓜蒌5份、木通3份、陈皮8份、白头翁6份、豆根7份、桑白皮3份、牛筋草6份、胆南星3份、天山雪莲6份、郁李仁5份、泽泻5份、桂皮8 份、花椒9份，贝母6份。临床实验证明，本发明能够安全有效治疗化脓性肺炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗化脓性肺炎的中药。
背景技术
化脓性肺炎也叫肺化脓，是由于多种病因所引起的肺组织化脓性炎症，目前化脓性肺炎的治疗主要是应用大剂量抗生素，这种治疗方式退烧不理想，疗效低，且容易产生耐药性。因此研究开发一种安全有效治疗化脓性肺炎的中药非常有临床实用价值。
本发明中药所涉及药材的研究现状如下：
鹅不食草：本品为菊科植物鹅不食草Centipedaminima(L.)A.Br.etAschers.的干燥全草。【性味与归经】辛，温。归肺经。【功能与主治】发散风寒，通鼻窍，止咳。用于风寒头痛，咳嗽痰多，鼻塞不通，鼻渊流涕。【用法与用量】6～9g。外用适量。
白及：本品为兰科植物白及Bletilla striata（Thunb.） Reichb. f.的干燥块茎。【性味】苦、甘、涩，微寒。【归经】归肺、肝、胃经。【功能主治】收敛止血，消肿生肌。用于咳血吐血，外伤出血，疮疡肿毒，皮肤皲裂；肺结核咳血，溃疡病出血。【用法用量】 6～15g，
茵陈：本品为菊科植物茵陈蒿Artemisia capillaris Thunb.的干燥幼苗。【性味】苦、辛，微寒。【归经】归脾、胃、肝、胆经。【功能主治】清湿热，退黄疸。用于黄疸尿少，湿疮瘙痒；传染性黄疸型肝炎。【用法用量】 6～15g。
瓜蒌：本品为葫芦科植物栝楼Trichosanthes kirilowii Maxim. 或双边栝楼Trichosan-thes rosthornii Harms 的干燥成熟果实。【性味】甘、微苦、寒。【归经】归肺、胃、大肠经。【功能主治】清热涤痰，宽胸散结，润燥滑肠。用于肺热咳嗽，痰浊黄稠，胸痹心痛，结胸痞满，乳痈，肺痈，肠痈肿痛，大便秘结。【用法用量】 9～15g。
木通：本品为木通科植物木通、三叶木通或白木通的滕茎。【性味】苦；性寒。【归经】心；脾；肾；小肠；膀胱经。【功能主治】清热利尿；活血通脉。主小便赤赤；淋浊；水肿；胸中烦热；喉喉疼痛；口舌生疮；风湿痹痛；乳汁不通；经闭；痛经。【用法用量】3-6g。
白头翁：本品为毛茛科植物白头翁Pulsatilla chinensis （Bge.） Regel的干燥根。[性味】苦，寒。【归经】归胃、大肠经。【功能主治】清热解毒，凉血止痢。用于热毒血痢，阴痒带下，阿米巴痢。【用法用量】 9～15g。
豆根：本品为豆科木蓝属植物花木蓝Indigofera Kirilowii Maxim. ex Palibin，以根入药。【性味】苦，寒。【功能主治】清热解毒，消肿止痛，通便。用于咽喉肿痛，肺热咳嗽，黄疸，热结便秘；外用治痔疮肿痛，蛇虫咬伤。
桑白皮： 本品为桑科植物桑Morus alba L.的干燥根皮。【性味】甘，寒。【归经】归肺经。【功能主治】泻肺平喘，利水消肿。用于肺热喘咳，水肿胀满尿少，面目肌肤浮肿。【用法用量】 6～12g。
牛筋草：为禾本科蟋蟀草属植物牛筋草Eleusine indica （L.）Gaertn.的全草。【性味】甘、淡，平。【功能主治】清热解毒，祛风利湿，散瘀止血。用于防治流行性乙型脑炎、流行性脑脊髓膜炎，风湿性关节炎，黄疸型肝炎，小儿消化不良，肠炎，痢疾，尿道炎；外用治跌打损伤，外伤出血，狗咬伤。
胆南星：本品为为制天南星细粉与牛、羊或猪胆汁拌制或生天南星细粉与牛、羊或猪胆汁经发酵而制成的加工品。【性味】味苦；微辛；性凉。【归经】肝；胆；肺经。【功能主治】清火化痰；熄风定惊。主中风；惊风；癫痫；头痛；眩晕；喘嗽。【用法用量】3-6g。
天山雪莲：本品系维吾尔族习用药材。为菊科植物天山雪莲Saussureainvolucrata(Kar.etKir.)Sch.Bip.的干燥地上部分。【功能与主治】维吾尔医：补肾活血，强筋骨，营养神经，调节异常体液。用于风湿性关节炎，关节疼痛，肺寒咳嗽，肾与小腹冷痛，白带过多等。中医：温肾助阳，祛风胜湿，通经活血。用于风寒湿痹痛、类风湿性关节炎，小腹冷痛，***。【用法与用量】3～6g，水煎或酒浸服。外用适量。【禁忌】孕妇忌用。
郁李仁：本品为蔷薇科植物欧李PrunushumilisBge.、郁李PrunusjaponicaThunb.或长柄扁桃PrunuspedunculataMaxim.的干燥成熟种子。【性味与归经】辛、苦、甘，平。归脾、大肠、小肠经。【功能与主治】润肠通便，下气利水。用于津枯肠燥，食积气滞，腹胀便秘，水肿，脚气，小便不利。【用法与用量】6～10g。【注意】孕妇慎用。
泽泻：本品为泽泻科植物泽泻Alismaorientalis(Sam.)Juzep.的干燥块茎。【性味与归经】甘、淡，寒。归肾、膀胱经。【功能与主治】利水渗湿，泄热，化浊降脂。用于小便不利，水肿胀满，泄泻尿少，痰饮眩晕，热淋涩痛，高脂血症。【用法与用量】6～10g。
桂皮：为樟科植物天竺桂、阴香、细叶香桂或川桂等的树皮。【性味】辛；甘；性温。【归经】脾；胃；肝；肾。【功能主治】温脾胃；暖肝肾；祛寒止痛；散瘀消肿。主脘腹冷痛；呕吐泄泻；腰膝酸冷；寒疝腹痛；寒湿痹痛；瘀滞痛经；血痢；肠风；跌打肿痛。【用法用量】6-12g。
花椒：【来源】本品为芸香科植物青椒（香椒、青花椒、山椒、狗椒）Zanthoxylum schinifolium Sieb. et Zucc.或花椒（蜀椒、川椒、红椒、红花椒、大红袍）Zantho xylum bungeanum Maxim.的干燥成熟果皮（花椒）及种子（椒目）入药。【性味】辛，温。【归经】归脾、胃、肾经。【功能主治】温中止痛，杀虫止痒。用于脘腹冷痛，呕吐泄泻，虫积腹痛，蛔虫症；外治湿疹瘙痒。【用法用量】 3～6g。外用适量，煎汤熏洗。
贝母：本品为百合科植物暗紫贝母、卷叶贝母、棱砂贝母、甘肃贝母、康定贝母等的鳞茎。【性味】味甘、苦；性微寒。【归经】归肺；心经。【功能主治】清热润肺；化痰止咳；散结消肿。主肺虚；久咳；虚劳咳嗽；燥热咳嗽；肺痈；瘰疬；痈肿；乳痈。【用法用量】3-9g。
发明内容
本发明旨在提供一种治疗化脓性肺炎的中药，通过选择合适的药材及其配比，达到安全有效治愈化脓性肺炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗化脓性肺炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：鹅不食草4份、白及4份、茵陈5份、瓜蒌5份、木通3份、陈皮8份、白头翁6份、豆根7份、桑白皮3份、牛筋草6份、胆南星3份、天山雪莲6份、郁李仁5份、泽泻5份、桂皮8 份、花椒9份，贝母6份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年1月-2011年12月间共收集50例化脓性肺炎患者，其中男30例，女20例，年龄1-71岁，病程6天-3个月。随机分为：治疗组25例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照组口服阿莫西林片，疗程10天。
治疗组口服本发明按照具体实施例1制得的胶囊，每日2次。疗程10天。
2.2观察项目：实验前后，对咳嗽，体温，血液生化指标化验记录。X光透视比对记录。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，治愈后三个月内未见复发。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状、实验室检查无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 25 | 18 | 6 | 1 | 0 | 96% |
| 对照组 | 25 | 5 | 13 | 7 | 4（16%） | 72% |
可见，本发明制得的药物能够安全有效治疗化脓性肺炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：鹅不食草4克、白及4克、茵陈5克、瓜蒌5克、木通3克、陈皮8克、白头翁6克、豆根7克、桑白皮3克、牛筋草6克、胆南星3克、天山雪莲6克、郁李仁5克、泽泻5克、桂皮8 克、花椒9克，贝母6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗化脓性肺炎。口服，每日分早晚两次服用。
具体实施例2
称取：鹅不食草4克、白及4克、茵陈5克、瓜蒌5克、木通3克、陈皮8克、白头翁6克、豆根7克、桑白皮3克、牛筋草6克、胆南星3克、天山雪莲6克、郁李仁5克、泽泻5克、桂皮8 克、花椒9克，贝母6克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人一天用量的散剂。
用于治疗化脓性肺炎。口服，每日一次。
具体实施例3
称取：鹅不食草4克、白及4克、茵陈5克、瓜蒌5克、木通3克、陈皮8克、白头翁6克、豆根7克、桑白皮3克、牛筋草6克、胆南星3克、天山雪莲6克、郁李仁5克、泽泻5克、桂皮8 克、花椒9克，贝母6克，加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗化脓性肺炎。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗化脓性肺炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：鹅不食草4份、白及4份、茵陈5份、瓜蒌5份、木通3份、陈皮8份、白头翁6份、豆根7份、桑白皮3份、牛筋草6份、胆南星3份、天山雪莲6份、郁李仁5份、泽泻5份、桂皮8 份、花椒9份，贝母6份。
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| CN101757541A (zh) * | 2009-11-05 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗肝腹水病证的中药组合物及其制备方法 |
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| CN101757541A (zh) * | 2009-11-05 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗肝腹水病证的中药组合物及其制备方法 |
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