CN103536860A - Health care product capable of improving sleep - Google Patents

Health care product capable of improving sleep Download PDF

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Publication number
CN103536860A
CN103536860A CN201310540079.2A CN201310540079A CN103536860A CN 103536860 A CN103536860 A CN 103536860A CN 201310540079 A CN201310540079 A CN 201310540079A CN 103536860 A CN103536860 A CN 103536860A
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China
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health care
care product
parts
health product
sleep
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CN201310540079.2A
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Chinese (zh)
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吕明慧
黄界洲
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Guangdong Life No1 Pharmaceutical Co Ltd
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Guangdong Life No1 Pharmaceutical Co Ltd
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Abstract

The invention discloses a health care product capable of improving sleep. The health care product is prepared from the following raw materials: 1-50 parts of longan, 1-50 parts of tuber fleeceflower stem, 1-45 parts of spina date seed and 0.8-30 parts of turmeric. The health care product has the beneficial effects that the health care product is simple in formula and reasonable in compatibility and follows the principle of treatment based on syndrome differentiation in the traditional Chinese medicine science; the medicines in the formula supplement each other; animal experiments prove that the health care product has the obvious function of improving sleep, is nontoxic and harmless to human bodies, has the health care function of improving immunity and has high safety; the formula can be prepared into different dosage forms of health care products for improving sleep by utilizing the medically accepted conventional preparation methods of preparations, and easily achieves mass production.

Description

A kind of health product that improve sleep
Technical field
The present invention relates to a kind of health product, specifically a kind of health product that improve sleep, belong to field of health care products.
Background technology
The time in people's all one's life nearly 1/3 is spent in sleep.When people are in sleep state, can make people's brain and health be had a rest, rest and reorganize and recover, rationally fully sleep and have a rest and be conducive to the daily working and learning of people, higher sleep quality is the work guarantees of learning life of people.World Health Organization's investigation demonstration, the whole world approximately has 29% people to have various sleeping problems, and the prevalence of Chinese residents sleep disorder is up to 42.7%.
Relevant research shows: while not having enough sleep, have following harm: (1) affects the creative thinking of brain: the ability that can affect the creative thinking of brain and processing things as not having enough sleep for a long time; (2) affect teen-age growth promoter: the secretion of teen-age growth promoter and growth hormone has certain relation, and the secretion of growth hormone is closely related with sleep, people has a large growth hormone secretion peak after sleeping soundly, there are again subsequently several little secretion peaks, and at non-sleep state, growth hormone secretion reduces; (3) cutaneous health: sufficient sleep can make people's skin obtain good metabolism, do not have enough sleep and can cause that the capillary of skin stasis of blood is stagnant, circulation is obstructed, make the cell of skin can not get sufficient nutrition, thereby accelerate the aging of skin, make skin color seem dark and gloomy and pale, easily occur black eye blackout and wrinkle; (4) cause disease to occur: often not have enough sleep or sleep disordered, can affect the proper splitting of cell, can make people's mood worried anxious, immunity reduces, neurasthenia, flu, gastrointestinal disease etc. can cause thus all diseases to occur, as even may produced the sudden change of cancerous cell and cause the generation of cancer; (5) cause obesity: do not have enough sleep and can cause the decline of human body internal diabetes lipoprotein concentration, can cause the rising of appetite hormone concentration in human body simultaneously.
Because people exist the different pressures from each side in social life, therefore, sleeping problems become a phenomenon general in " subhealth state " crowd.For more and more general sleeping problems, people have developed for improving the health product of sleep, or take that Chinese medicine is main component, Western medicine is main component for take of having, and along with the progress of technology and the development of technique, the dosage form of health product also emerges in an endless stream, as oral liquid, tablet, electuary, decoction pieces etc.
For example, patent ZL200910040342.5 discloses a kind of tablet that improves sleep, and its active component is made by the raw material of following weight ratio: Cortex Albiziae 15-20, Semen Platycladi 20-25, Radix Polygalae 10-15G, Os Draconis 10-15, Concha Ostreae 15-20, Bulbus Lilii 20-25, Fructus Jujubae 15-20, Caulis Polygoni Multiflori 15-20, Caulis Polygoni Multiflori 15-20, Radix Scrophulariae 5-10, Radix Salviae Miltiorrhizae 10-20, Rhizoma Gastrodiae 5-10, Semen arachidis hypogaeae 10-15, Cinnabaris 1-3; Patent CN1171620C discloses a kind of health food that improves sleep, and it is to be prepared from by Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Ganoderma, Radix Ginseng; Patent CN 101019980 B disclose the improvement sleep oral liquid of a kind of invigorating the heart and spleen that has Semen Ziziphi Spinosae, Rhizoma Dioscoreae, Radix Platycodonis, Colla Corii Asini, Radix Polygalae, Semen Platycladi, Radix Glycyrrhizae Preparata, Bulbus Lilii, the Radix Paeoniae Alba to make, nourishing blood to tranquillize the mind; Patent CN100562327C is disclosed a kind of for improving health food of sleep and preparation method thereof, described in it, health product are through alcohol extraction, reduced vacuum, to be concentrated, be dried the dry high powder that makes Fructus Schisandrae Chinensis, Herb Gynostemmae Pentaphylli, Radix Et Caulis Acanthopanacis Senticosi, Semen Ziziphi Spinosae extract respectively by walnut oil, Fructus Schisandrae Chinensis, Herb Gynostemmae Pentaphylli, Radix Et Caulis Acanthopanacis Senticosi, Semen Ziziphi Spinosae, then make after mixing homogeneously with walnut oil.
Existing for improving sleep, health product with Chinese crude drug composition, generally by being permitted several kinds of Chinese medicinal materials, it is mostly the prescription of 5 kinds or above composition, complicated component, adopt traditional extraction method for concentration and process conditions to produce, tend to run into because component is numerous, unified working condition cannot meet the concentrated requirement of extraction of ingredients one by one, caused the extraction of medical material effective ingredient or active component incomplete, the effect that has affected final products becomes, if and in order fully to obtain the effective ingredient of ingredients, adopt different working conditions or extracting method, can cause the increase of cost, also be unfavorable for large the carrying out producing.
Summary of the invention
The object of the invention is for the deficiencies in the prior art, and a kind of health product that improve sleep are provided, and its formula is simple, but its compatibility is reasonable, follows the principle of tcm treatment according to syndrome differentiation, and each taste medicine of filling a prescription complements each other, the effect that tool improves significantly and sleeps; Meanwhile, this formula can utilize the conventional preparation method of the preparation of medically approving to be prepared into the health product of the improvement sleep of different dosage form.
For addressing the above problem, the technical solution adopted in the present invention is: a kind of health product that improve sleep function, by the raw material of following parts by weight, made: Arillus Longan 1-50 part, Caulis Polygoni Multiflori 1-50 part, Semen Ziziphi Spinosae 1-45 part, Rhizoma Curcumae Longae 0.8-30 part.
Preferably the weight proportion of each raw material is: Arillus Longan 2-40 part, Caulis Polygoni Multiflori 2-40 part, Semen Ziziphi Spinosae 1-40 part, Rhizoma Curcumae Longae 1-20 part.
The weight proportion of each best raw material is: Arillus Longan 2-35 part, Caulis Polygoni Multiflori 2-35 part, Semen Ziziphi Spinosae 1-25 part, Rhizoma Curcumae Longae 1-15 part.
In described health product, the mass fraction of contained crude polysaccharides is 3.8-5.0%, and contained total saponins mass fraction is 0.07-0.1%.
Described health food adopts common process to add adjuvant required while preparing different preparation, makes soft capsule, hard capsule, granule, tablet or oral liquid.
The effect of main component of the present invention or the effect playing are as follows:
(1) Arillus Longan, another name: Fructus Alpiniae Oxyphyllae, than order, Fructus Litchi slave, sub-Fructus Litchi, wooden round, black horse pearl, swallow ovum, shark tear, circle eye, sweet spleen, unit's meat etc., Sapindaceae (Sapindaceae) Euphoria (Dimocarpus), Arillus Longan sweet in the mouth is warm in nature, GUIXIN, spleen channel, be applicable to syndrome of deficiency of both heart and spleen and qi-blood deficiency syndrome patient, frail, the insomnia for the treatment of asthenia, forgetful, palpitation with fear, palpitation with a distress feeling, the dizzy effect of having a guilty conscience are remarkable, and Arillus Longan contains protein, fat, saccharide, organic acid, crude fibre and multivitamin and mineral etc.Arillus Longan can suppress lipid peroxidation and improve activities of antioxidant enzymes, points out it to have certain anti-aging effects; Arillus Longan has raising body's immunity, inhibition tumor cell, and blood fat reducing, increases coronary artery blood flow, the effects such as enhancing body quality;
(2) Semen Ziziphi Spinosae, another name Semen Ziziphi Spinosae, Fructus Choerospondiatis, Semen Ziziphi Spinosae, nature and flavor: sweet, flat; Gui Jing: heart channel; Spleen channel; Liver Channel; Gallbladder meridian, function: mind tranquilizing and the heart calming; Nourishing the liver; Arresting sweating, cures mainly: restlessness of asrhenia type and insomnia; Palpitation with fear palpitation with a distress feeling; The empty spontaneous perspiration of body, night sweat.Semen Ziziphi Spinosae nourishing the liver, mind calming, calms the nerves, arresting sweating.Effect: have calmness, hypnosis, analgesia, anticonvulsant action; There is certain hypotensive effect; There is to excitation in uterus; For deficiency of YIN-blood, severe palpitation, insomnia forgetfulness; The empty hyperhidrosis of body;
(3) Rhizoma Curcumae Longae, another name: tripod perfume, Dioscorea zingiberensis, hair Rhizoma Curcumae Longae, Huang Siyu, bitter in the mouth, pungent; Warm in nature, return spleen channel, Liver Channel, there is the effect of removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia, cure mainly: all cards of stagnation of QI and blood; Born of the same parents' abdomen hypochondriac pain; Dysmenorrhes; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Rheumatic arthralgia; Traumatic injury; Carbuncle;
(4) Caulis Polygoni Multiflori, another name: chess rattan (< < Nanjing medicinal herbs > among the people >), Caulis Polygoni Multiflori (< < plants in Jiangsu medicine will > >), prescription name: Caulis Polygoni Multiflori, Caulis Polygoni Multiflori, Radix Polygoni Multiflori rattan, Polygonm multiflorum Thunb village, the sweet micro-hardship of property, taste is flat, enter the heart, spleen two is through (< < book on Chinese herbal medicine is new > > again), nourish heart, calm the nerves, dredging collateral, the effect of dispeling the wind, cure mainly: insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
The present invention with respect to the beneficial effect of prior art is: the present invention fills a prescription simply, compatibility is reasonable, follow the principle of tcm treatment according to syndrome differentiation, each taste medicine of filling a prescription complements each other, through animal experiment, prove, the effect that tool improves significantly and sleeps, nontoxic to human body, be improved the health-care effect of immunity, product safe; This formula can utilize the conventional preparation method of the preparation of medically approving to be prepared into the health product of the improvement sleep of different dosage form; While adopting conventional production process to extract the effective ingredient of formula Chinese crude drug, can obtain compared with high effective component yield and without adopting loaded down with trivial details production process, economy is strong, is easy to realize large production.
The specific embodiment
Below by embodiment, the present invention is described in further details, these embodiment are only used for illustrating the present invention, do not limit the scope of the invention.
embodiment 1raw material by following parts by weight adopts the following step to prepare health product of the present invention (teabag): 15 parts of Arillus Longan, 15 parts of Caulis Polygoni Multiflori, 8 parts of Semen Ziziphi Spinosaes, 5 parts, Rhizoma Curcumae Longae.
Preparation method is as follows:
(1) by prescription, get raw medicinal material, clean, be placed in extraction pot, add the water of 4 times of raw medicinal material weight, soak 2 hours, be heated to 100 ℃, keep decocting 1 hour at this temperature, filter, filtrate is stand-by;
(2) in extraction pot, add the water of 5 times of raw medicinal material weight, soak 1 hour, be heated to 100 ℃, keep decocting 2 hours at this temperature, filter, obtain filtrate;
(3) filtrate of twice acquisition being merged, is under 70 ℃ of conditions in temperature, vacuum 0.06 Mpa, and being concentrated into solid-liquid ratio, to focus on while measuring under 55 ℃ of conditions be 1.15 acquisition fluid extracts;
(4) fluid extract is adopted to common process is granulated, oven dry, granulate, mixing, packing, obtains.
After testing, the mass fraction that finally obtains the crude polysaccharides of product is 4.0%, and contained total saponins mass fraction is 0.07%.
Embodiment 2 adopts the following step to prepare health product of the present invention (oral liquid) by the raw material of following parts by weight: 35 parts of Arillus Longan, 30 parts of Caulis Polygoni Multiflori, 20 parts of Semen Ziziphi Spinosaes, 10 parts, Rhizoma Curcumae Longae.
Preparation method is as follows: first medical material is cleaned, decontamination, dry, be ground into granule, be placed in extraction pot, the pure water that adds 8 times of weight soaks 2 hours, then decoct 3 hours, filter, get filtrate, again to the pure water that adds 6 times in extraction pot, continue to decoct 2 hours, filter, twice filtrate is merged, be concentrated into 80 ℃ when measuring relative densities and being 1.05-1.1, take out concentrated solution, after cooling, add the kieselguhr that accounts for concentrated solution quality 0.2% to filter, obtain filtrate, add the potassium sorbate that accounts for filtrate quality 0.2%, be settled to 1L, mix homogeneously, be placed in 4 ℃ of following cold preservations 48 hours, by specification fill, 105 ℃ of high temperature sterilizes, pack and get final product.The oral liquid that the present embodiment is made, every 100g is 4.5% containing the mass fraction of crude polysaccharides, containing total saponins mass fraction, is 0.08%.
embodiment 3raw material by following parts by weight adopts the following step to prepare health product of the present invention (teabag): 35 parts of Arillus Longan, 25 parts of Caulis Polygoni Multiflori, 13 parts of Semen Ziziphi Spinosaes, 10 parts, Rhizoma Curcumae Longae.
Preparation method is as follows:
(1) by prescription, get raw medicinal material, clean, be placed in extraction pot, add the water of 4 times of raw medicinal material weight, soak 2 hours, be heated to 100 ℃, keep decocting 1 hour at this temperature, filter, filtrate is stand-by;
(2) in extraction pot, add the water of 8 times of raw medicinal material weight, soak 2 hours, be heated to 100 ℃, keep decocting 2 hours at this temperature, filter, obtain filtrate;
(3) filtrate of twice acquisition being merged, is under 65 ℃ of conditions in temperature, vacuum 0.06 Mpa, and being concentrated into solid-liquid ratio, to focus on while measuring under 45 ℃ of conditions be 1.2 acquisition fluid extracts;
(4) fluid extract is adopted to common process is granulated, oven dry, granulate, mixing, packing, obtains.
After testing, the mass fraction that finally obtains the crude polysaccharides of product is 4.0%, and contained total saponins mass fraction is 0.08%.

Claims (5)

1. health product that improve sleep function, is characterized in that: the raw material by following parts by weight is made: Arillus Longan 1-50 part, Caulis Polygoni Multiflori 1-50 part, Semen Ziziphi Spinosae 1-45 part, Rhizoma Curcumae Longae 0.8-30 part .
2. the health product that improve sleep function according to claim 1, is characterized in that: wherein the weight proportion of each raw material is: Arillus Longan 2-40 part, Caulis Polygoni Multiflori 2-40 part, Semen Ziziphi Spinosae 1-40 part, Rhizoma Curcumae Longae 1-20 part .
3. the health product that improve sleep function according to claim 1, is characterized in that: wherein the weight proportion of each raw material is: Arillus Longan 2-35 part, Caulis Polygoni Multiflori 2-35 part, Semen Ziziphi Spinosae 1-25 part, Rhizoma Curcumae Longae 1-15 part .
4. the health product that improve sleep function according to claim 1, is characterized in that: in described health product, the mass fraction of contained crude polysaccharides is 3.8-5.0%, and contained total saponins mass fraction is 0.07-0.1%.
5. health food according to claim 1, is characterized in that: described health food adopts common process to add adjuvant required while preparing different preparation, makes soft capsule, hard capsule, granule, tablet or oral liquid.
CN201310540079.2A 2013-11-05 2013-11-05 Health care product capable of improving sleep Pending CN103536860A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104664371A (en) * 2015-01-28 2015-06-03 刘高胜 Chewable tablets for improving sleeping quality
CN104886445A (en) * 2015-05-15 2015-09-09 山西大学 Health-care food for improving sleep
CN105996012A (en) * 2016-08-12 2016-10-12 张彦优 Sleep-improvement health product
CN107279637A (en) * 2017-06-20 2017-10-24 刘朋明 A kind of Polygonum multiflower knotweed fermented beverage for improving sleep quality and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1509737A (en) * 2002-12-23 2004-07-07 江苏康缘药业股份有限公司 Chinese medicinal composition with delaying senility and improving sleep functions, and preparing method thereof
CN102755511A (en) * 2012-07-18 2012-10-31 马千里 Traditional Chinese medicine health-care powder for treating insomnia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1509737A (en) * 2002-12-23 2004-07-07 江苏康缘药业股份有限公司 Chinese medicinal composition with delaying senility and improving sleep functions, and preparing method thereof
CN102755511A (en) * 2012-07-18 2012-10-31 马千里 Traditional Chinese medicine health-care powder for treating insomnia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHENGING88: "好睡点康健袋泡茶", 《百度百科,HTTP://WWW.BAIKE.BAIDU.COM/VIEW/2860164.HTM》, 5 October 2009 (2009-10-05), pages 1 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104664371A (en) * 2015-01-28 2015-06-03 刘高胜 Chewable tablets for improving sleeping quality
CN104886445A (en) * 2015-05-15 2015-09-09 山西大学 Health-care food for improving sleep
CN105996012A (en) * 2016-08-12 2016-10-12 张彦优 Sleep-improvement health product
CN107279637A (en) * 2017-06-20 2017-10-24 刘朋明 A kind of Polygonum multiflower knotweed fermented beverage for improving sleep quality and preparation method thereof

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Application publication date: 20140129