CN103536835A - Preparation method of medicine for reinforcing spleen to promote digestion - Google Patents
Preparation method of medicine for reinforcing spleen to promote digestion Download PDFInfo
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- CN103536835A CN103536835A CN201310464654.5A CN201310464654A CN103536835A CN 103536835 A CN103536835 A CN 103536835A CN 201310464654 A CN201310464654 A CN 201310464654A CN 103536835 A CN103536835 A CN 103536835A
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Abstract
The invention relates to a preparation method of a medicine for reinforcing the spleen to promote digestion, which comprises the following steps: 1. taking the following raw materials in parts by weight for later use: 30 parts of raw radix astragali, 30 parts of Chinese yam, 15 parts of stir-fried Bighead Atractylodes Rhizome, 30 parts of coix seed, 10 parts of coptis, 30 parts of taraxacum, 15 parts of angelica, 6 parts of honey-fried licorice root, 20 parts of dendrobe, 15 parts of eucommia, 10 parts of Baikal skullcap root, 15 parts of teasel root, 15 parts of tuckahoe, 10 parts of Jade Butterfly, 10 parts of Mangnolia officinalis, 10 parts of cassia twig, 30 parts of herba agrimoniae, 10 parts of amomum fruit, 15 parts of hyacinth bletilla, 15 parts of white peony root, 15 parts of semen dolichoris album and 10 parts of fructus aurantii; and 2. mixing the active pharmaceutical ingredients, drying, pulverizing into fine powder, passing through a 500-mesh screen and encapsulating. The medicine has unexpected effects in the aspect of reinforcing spleen to promote digestion.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specially a kind of preparation method of strengthening the spleen to promote digestion medicine.
Background technology
Insufficiency of the spleen dysfunction of the spleen in transportation and transformation, and can occur malnutrition, water liquid loses in spreading and the raw wet expectorant of making, or the disease such as lose blood.Its disease is at stomach, and dyspepsia relates to the internal organs such as liver spleen, and suitable determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, gives invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, the method treatments such as dyspepsia and intestinal stasis relieving.But western medicine side effect is larger, the Chinese patent medicine DeGrain that market is similar.
Summary of the invention
The object of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, provides a kind of preparation method of strengthening the spleen to promote digestion medicine according to Chinese medical theory.
This method:
Get by weight 30 parts of crude drug Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 15 parts of Semen Lablab Albums and 10 parts of Fructus Aurantiis standby;
Second step: after above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate.
Method provided by the invention, its raw material is Radix Astragali, Rhizoma Dioscoreae, Rhizoma Atractylodis Macrocephalae (parched), Semen Coicis, Rhizoma Coptidis, Herba Taraxaci, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata, Herba Dendrobii, the Cortex Eucommiae, Radix Scutellariae, Radix Dipsaci, Poria, Semen Oroxyli, Cortex Magnoliae Officinalis, Ramulus Cinnamomi, Herba Agrimoniae, Fructus Amomi, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, Fructus Aurantii and Semen Lablab Album, can be used for the vomiting that treatment causes because of insufficiency of the spleen and dyspepsia, abdominal distention and become thin etc., the effect with certain strengthening the spleen to promote digestion that above-mentioned medical material has, the effect with certain building body having, this formula is in R&D process, the formula of take in the patent of applying for is on the same day core, the additional formula drawing by increase and decrease flavour of a drug and adjustment compatibility relationship, wherein Semen Lablab Album has spleen reinforcing dehumidifying, Semen Coicis can spleen reinforcing eliminating dampness by diuresis.Semen Lablab Album, Semen Coicis is compatible with this ratio, eliminating dampness and diuresis contributes to treatment to have loose bowels, for vomiting and diarrhoea, hand over and make to have good action, and the Rhizoma Dioscoreae effect of reinforcing the kidney itself adds Rhizoma Dioscoreae and Semen Lablab Album to match as ministerial drug and monarch drug Semen Coicis, because after insufficiency of the spleen inability of food and drink to be digested and transported vital essence, there is water wet dirty, have an astringency inducing.So with above-mentioned raw materials medicine carries out according to the combination principle of monarch, after the compatibility of rational proportion, having strengthened spleen reinforcing exsiccation.Because Seem Lablab Album can removing dampness also can dampness removing, Semen Coicis beyond spleen reinforcing, dampness removing is main.Carry out according to the combination principle of monarch with above-mentioned raw materials medicine after the compatibility of rational proportion, should say that QI invigorating dehumidifying strength is much bigger.And picture Rhizoma Dioscoreae this class, on can lung moistening, in can spleen reinforcing, lower can reinforcing the kidney, looks after more comprehensive.At insufficiency of the spleen, dyspepsia, vomiting, abdominal distention for the treatment of and the aspect such as become thin, obtain the curative effect of showing, made this medicine aspect strengthening the spleen to promote digestion, produce beyond thought effect.And the present invention is pure Chinese medicinal preparation, through 1 year, observe both without recurring also without obvious toxic and side effects.
The specific embodiment
A preparation method for strengthening the spleen to promote digestion medicine, by following bulk drugs, made:
Radix Astragali 30g, Rhizoma Dioscoreae 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Semen Coicis 30g, Rhizoma Coptidis 10g, Herba Taraxaci 30g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae Preparata 6g, Herba Dendrobii 20g, Cortex Eucommiae 15g, Radix Scutellariae 10g, Radix Dipsaci 15g, Poria 15g, Semen Oroxyli 10g, Cortex Magnoliae Officinalis 10g, Ramulus Cinnamomi 10g, Herba Agrimoniae 30g, Fructus Amomi 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Paeoniae Alba 15g, Fructus Aurantii 10g and Semen Lablab Album 10g;
Second step: after above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate.Every capsule has above-mentioned raw materials medicine 0.4g.
The drug effect of each taste crude drug is as follows:
1. Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
2. Rhizoma Dioscoreae: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
3. Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.
4. Semen Coicis: spleen invigorating, eliminating dampness by diuresis, antidiarrheal, evacuation of pus.
5. Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
6. Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
7. Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
8. Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
9. Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.
10. the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
11. Radix Scutellariaes: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
12. Radix Dipsacis: invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.
13. Poria: Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.
14. Semen Oroxylis: lung moistening, soothing liver-QI, stomach function regulating, granulation promoting.
15. Cortex Magnoliae Officinalis: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.
16. Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.
17. Herba Agrimoniaes: astringing to arrest bleeding, detoxification sore treatment, parasite killing, puckery antiperspirant, cough-relieving.
18. Fructus Amomis: removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.
19. Pseudobulbus Bletillae (Rhizoma Bletillae)s: tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.
20. Radix Paeoniae Albas: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
21. Fructus Aurantiis: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.
22. Semen Lablab Albums: spleen reinforcing and in, removing dampness is relieved summer heat.
Instructions of taking: above people was three times on the one in 18 years old, each 1.Within 30 days, be a course for the treatment of, take continuously three courses for the treatment of.As take continuously 1 week symptom without obviously change or take medicine after occur that diarrhoea and vomiting increase the weight of, drug withdrawal immediately, transference cure after drug withdrawal.
Clinical trial:
Choose 150 routine functional dyspepsias and with gastrointestinal upset as vomiting, abdominal distention and the Patients of Spleen Deficiency of becoming thin, in age 18-50 year, the course of disease is more than 3 months, in 2 months, do not carry out any treatment.Above-mentioned 150 routine patients are divided into two groups for the treatment of group and matched groups, treatment group 100 examples, the capsule making with this enforcement is treated, and three times on the oral one, each 1 30 days is a course for the treatment of, takes continuously three courses for the treatment of.Matched group 50 examples, take domperidone tablet treatment: oral, 10～20mg or suspension 10ml, every day 3～4 times, take 15～30 minutes ante cibum, within 15 days, is a course for the treatment of, takes continuously three courses for the treatment of.Then carry out clinical observation.
Period in a medicine treatment group self clinical observation on the therapeutic effect analysis result is as follows:
| Curative effect project | Treatment group number of cases | Improvement rate (%) |
| Vomiting number of times reduces | 90 | 90% |
| Abdominal distention is alleviated | 86 | 86% |
| Body weight increases | 88 | 88% |
| Appetite increases | 96 | 96% |
| Total improvement rate (%) | ? | 90% |
The clinical observation on the therapeutic effect analysis result of period in a medicine treatment group and matched group is as follows:
Efficacy assessment standard is as follows:
1, effective: vomiting is obviously controlled, and abdominal distention is obviously alleviated, body weight increases, and appetite increases, the transference cure of all the other gastrointestinal upsets.
2, take a turn for the better: vomiting number of times reduces or the intermittent time extends, and abdominal distention is alleviated to some extent, and body weight stops alleviating, and appetite makes moderate progress, and the symptom partial symptoms of all the other gastrointestinal upsets disappears.
3, invalid: symptom is without improving or increasing the weight of.
The comparison sheet of the clinical medicine side effect incidence rate of period in a medicine treatment group and matched group
Stomachache and Refuse to take medicine are clinical modal side effect as can be seen from the above table, but can progressively disappear after drug withdrawal.But tremble and the incidence rate of the side effect of having blood in stool, take the matched group of domperidone tablet apparently higher than the treatment group of taking capsule of the present invention, so the present invention does not have obvious toxic and side effects substantially.
Claims (1)
1. a preparation method for strengthening the spleen to promote digestion medicine, is characterized in that comprising the steps:
The first step: it is standby to get by weight 30 parts of crude drug Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 15 parts of Semen Lablab Albums and 10 parts of Fructus Aurantiis;
Second step: after above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate.
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Cited By (2)
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| CN103800801A (en) * | 2014-03-11 | 2014-05-21 | 朱克兰 | Traditional Chinese medicine composition for treating pica and preparation method thereof |
| CN104127786A (en) * | 2014-07-04 | 2014-11-05 | 黄秋云 | Stomach nourishing medicine and stomach nourishing steamed bread prepared by medicine |
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| CN104127786A (en) * | 2014-07-04 | 2014-11-05 | 黄秋云 | Stomach nourishing medicine and stomach nourishing steamed bread prepared by medicine |
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Effective date of registration: 20170612 Address after: 226500 Jiangsu city of Nantong province Rugao City Snow shore town Nanling neighborhood 6 groups Patentee after: Rugao Nanling hospital Address before: 430000 Hubei city of Wuhan province Optics Valley East Lake New Technology Development Zone, Road No. 58 South Fuxing garden of medicine of 4 7 storey building No. 02 Patentee before: Wuhan Hong Xintong Science and Technology Ltd. |
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