CN103520044A - Maca toothpaste composition, as well as preparation method and application thereof - Google Patents
Maca toothpaste composition, as well as preparation method and application thereof Download PDFInfo
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- CN103520044A CN103520044A CN201310482787.5A CN201310482787A CN103520044A CN 103520044 A CN103520044 A CN 103520044A CN 201310482787 A CN201310482787 A CN 201310482787A CN 103520044 A CN103520044 A CN 103520044A
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Abstract
The invention provides a maca toothpaste composition, comprising toothpaste matrix, wherein the maca toothpaste composition also comprises maca raw powder and/or maca dry extract, preferably, the maca raw powder and/or maca dry extract accounts for 0.1-10wt% of total weight of the toothpaste composition. The invention also provides a method for preparing the maca toothpaste composition, and application of the maca toothpaste composition in preparation of health-care products, foods or drugs for relieving fatigue, enhancing energy or improving sexual function.
Description
Technical field
The present invention relates to a kind of dentifrice composition containing plant component, be specifically related to a kind of Maca dentifrice composition, and method and the application of preparing this Maca dentifrice composition.
Background technology
Maca (MACA) is crucifer, is similar to the rhizome of Radix Raphani sample hypertrophy, is mainly grown in the area, plateau, Andes of more than 4000 meter of Peru's middle part height above sea level, is one of local Inca's food source.From the sixties in 20th century, the researcher of South America and some other country has carried out pharmacological effect, toxicity and clinical and experimental study to Maca, has confirmed that Maca has the multiple efficacies such as resisting fatigue.First, the content of the pure Maca powder of 100g mineral zinc is 3.8mg, zinc is that the related Some Related Enzymes of energy metabolism is as necessary in lactic acid dehydrogenase, and the relation of zinc and neuro-endocrinology hormone is also closer, and zinc can be by regulating neuro-endocrinology hormone level to strengthen antifatigue effect under high temperature; Secondly, in Maca, also have some compositions also to have certain comprehensive antifatigue effect as vitamin B1, vitamin B2, linoleic acid, linolenic acid, sterol etc.; Finally, the synergism of the various functional components that comprise in Maca, can guarantee that body keeps the relatively constant of organization internal physicochemical property when fatigue, alleviates or avoids the overtired of each histoorgan of health.
At present, the picked-up approach of Maca comprises: beat to chew, make after taking, cut into slices with warm water after powder after medicated wine is taken and be brewed to tablet or capsule and take.Traditional acquisition method (for example brew, eat raw) is difficult to make full use of and absorb the effective ingredient in Maca, and by Maca beat take after powder and cut into slices after chew and have comparatively strong pungent sense.In order to alleviate or to avoid this pungent mouthfeel, conventionally Maca is made to the forms such as tablet, capsule or medicated wine.Although these picked-up approach have solved sensory issues, but for taking, brought inconvenience and limitation, for example, Tablet and Capsula agent needs water to take conventionally, and medicated wine itself still has pungent, and be not suitable for taking before driving.At present also need to find a kind of more convenient mode of effectively absorbing Maca.
Toothpaste is a kind of common daily living article, is used for cleaning oral cavity, tooth-whitening or prevent odontopathy.Recently, along with improving constantly of people's living standard, health perception also, in continuous enhancing, is also had higher requirement for dental care products.For example, consumer not only pays close attention to oral cavity cleaning effect itself when choosing toothpaste, also favors in whitening, prevents and treats other effects such as odontopathy or oral disease.Yet, the rarely seen tooth paste product with special efficacy or effect still in the market.
Summary of the invention
The object of the invention is to overcome defect of the prior art, a kind of Maca dentifrice composition is provided.Particularly, the present invention has proposed to have the dentifrice composition of anti-fatigue effect first.This dentifrice composition is retaining on the basis of Maca nutritive and health protection components, convenient people's picked-up.The present invention also provides the method for preparing this Maca dentifrice composition, and described Maca dentifrice composition for the preparation of fatigue alleviating, strengthen energy or improve the application in health product, food or the medicine of sexual function.
The invention provides a kind of Maca dentifrice composition, this dentifrice composition comprises toothpaste matrix, also comprises Maca fecula and/or Maca dry extract.
According to dentifrice composition of the present invention, wherein, described Maca fecula and/or Maca dry extract account for 0.1～10wt.% of described dentifrice composition gross weight, are preferably 0.5～5wt.%, more preferably 1～2wt.%.Inventor's discovery, by selecting suitable Maca fecula and/or the content of Maca dry extract, dentifrice composition of the present invention can obtain effective anti-fatigue effect.
According to dentifrice composition of the present invention, wherein, described Maca fecula is to take Maca as raw material, after section, dry, pulverizing, sterilizing, makes; Described Maca dry extract is that Maca tuber is dropped in circulating extraction container by hot reflux, soaks, and passes into Steam Heating reflux, extract,, almost colourless to extracting solution, collects extracting solution and filters, concentrates, sprays dry and make.
According to dentifrice composition of the present invention, wherein, described toothpaste matrix can comprise abrasivus, thickening agent, wetting agent and surfactant.Preferably, in described dentifrice composition, described abrasivus accounts for 10～50wt.%, 20～40wt.% for example, and described thickening agent accounts for 0.1～5wt.%, 0.1～1wt.% for example, described wetting agent accounts for 10～35wt.%, 30～35wt.% for example, and described surfactant accounts for 0.01～5wt.%, 1～5wt.% for example, as 2wt.%, 3wt.% etc.
According to dentifrice composition of the present invention, wherein, described toothpaste matrix can also comprise one or more in sweeting agent, antiseptic, coloring agent and fumet.Preferably, at described dentifrice composition, described sweeting agent accounts for 0.1～10wt.%, 0.1～1wt.% for example, as 0.1～0.5wt.%, described antiseptic accounts for 0.1～1wt.%, described coloring agent accounts for 0.01～1wt.%, 0.1～1wt.% for example, and described fumet accounts for 1～5wt.%.
According to dentifrice composition of the present invention, wherein, described abrasivus can be selected from one or more in calcium hydrogen phosphate (as calcium phosphate dibasic anhydrous or dicalcium phosphate dihydrate), dalcium biphosphate, calcium carbonate, calcium pyrophosphate, tetrasodium pyrophosphate, aluminium hydroxide, aluminium oxide, magnesium carbonate, magnesium phosphate, insoluble Polymeric sodium metaphosphate., insoluble potassium metaphosphate, titanium oxide, silicon dioxide, moisture silicic acid, hydration Silicon stone, titanium silicate, Zirconium orthosilicate. and synthetic resin abrasivus (such as phenolic resins etc.).
Described thickening agent can be selected from carrageenin, sodium carboxymethyl cellulose, methylcellulose, ethyl cellulose, cellulose acetate, ethyl cellulose sodium, sodium alginate, cluck xanthan, tragakanta, karaya, arabia gum, locust bean gum, polyvinyl alcohol, sodium polyacrylate, carboxy vinyl polymer, polyvinyl pyrrolidone, card pool ripple resin, silica gel, aluminum silica gel, thickening property silicon dioxide, Wei Gemu gel, one or more in artificial lithium magnesium silicate and xanthan gum.
Described wetting agent can be selected from one or more in glycerol, Sorbitol, ethylene glycol, propylene glycol, Polyethylene Glycol, polypropylene glycol, xylitol and maltose alcohol.
Described surfactant can be selected from one or more in anion surfactant, cationic surfactant, non-ionic surface active agent and zwitterionic surfactant.As anion surfactant; can enumerate sodium lauryl sulfate, sodium lauryl sulfate, myristyl sodium sulfate, N-sodium lauroyl sarcosine, N-myristoyl-N-methylaminoacetic acid sodium, dodecylbenzene sodium sulfonate, hydrogenated coconut fatty acid oil list glycerol sulfate mono sodium, lauryl sulfoacetate sodium, a-alkene sulfonic acid sodium, the N-acyl taurine salt of the N-acyl glutamate of N-palmityl sodium glutamate etc., N-methyl-N acyl methyltaurin sodium etc. etc.As the agent of the clean property of non-ionic surface, can enumerate sucrose fatty acid ester, the sucrose fatty acid ester of fatty ester of maltose etc., maltitol fatty acid ester, the sugar alcohol fatty acid ester of lactose fatty acid ester etc., alkylolamides, the polyoxyethylene sorbitan fatty acid ester of polyoxyethylene sorbitan monostearate etc., the polyoxyethylene fatty acid ester of polyoxyethylene hardened castor oil etc., the fatty diglycollic amide of lauric monoethanolamide or diglycollic amide etc., sorbitan fatty acid ester, the senior alcohol ether of polyoxyethylene, poloxalkol, polyoxyethylene polyoxypropylene fatty acid ester, polyglyceryl fatty acid ester, Pu Luluonike (Pluronic) etc.In addition, as zwitterionic surfactant, can enumerate the N-alkyl diaminoethyl glycine of cocamido propyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazole betanin, N-lauryl diaminoethyl glycine, N-myristyl diaminoethyl glycine etc. or N-alkyl-1-hydroxyethyl imidazole betanin sodium etc.These surfactants both can be used separately, also can two or more also use.
Described sweeting agent can be selected from one or more in saccharin sodium, stevioside, Stevia rebaudiana (Bertoni) Hemsl extract, p-met hoxycinnamic aldehyde, NHDC, perillartine, glycyrrhizin, Talin and aspartyl-phenylalanine methyl ester.
Described antiseptic can be various p-Hydroxybenzoates, can also coordinate that benzoic acid is received by effective dose, cationic antibacterial of nonionic antibacterial of trichlorine Lignum Rhamnellae, benzyl oxide ethoxy ammonium, cetylpyridinium chloride etc., derived essential oil etc.
Described coloring agent can be selected from the water-insoluble coloring agent of titanium oxide, ultramarine, Prussian blue, iron oxide red, mica titanium, lake colours etc.
Described fumet can be selected from menthol, anise alcohol, carvone, acetaminol, limonene, positive certain herbaceous plants with big flowers alcohol, citronellol, a-terpinol, geraniol acetate, cineole, linalool, ethyl linalool, 4-hydroxyl-3-methoxylbenxaldehyde, thymol, Oleum Menthae Rotundifoliae, Oleum menthae, Fructus Citri Limoniae oil, orange peel oil, sage oil, oil of rosemary, Oleum Cinnamomi, allspice oil, Bay leaves oil, perilla oil, wintergreen oil, cloves oil or Folium eucalypti globueli (Eucalyptus globulus Labill.) wet goods.
Above-mentioned dentifrice composition can also comprise other additives, for example, can add fluorochemical caries prevention, and this fluorochemical comprises sodium fluoride, sodium monofluorophosphate, hexafluosilicic acid, prodan etc.
The present invention also provides the method for preparing above-mentioned Maca dentifrice composition, and wherein, the method comprises and takes Maca fecula and/or Maca dry extract and toothpaste matrix, after mixing, stirs, standing, obtains described dentifrice composition.Preferably, the time of described stirring is 0.5～2h, for example, be 1h.
The present invention also provide by above-mentioned Maca dentifrice composition or the Maca dentifrice composition that makes according to method of the present invention for the preparation of fatigue alleviating, strengthen energy or improve the application in health product, food or the medicine of sexual function.
Maca dentifrice composition of the present invention can have but be not limited to following beneficial effect:
1. by adopting formula of the present invention, the present invention has proposed a kind of dentifrice composition that has anti-fatigue effect concurrently first.Research shows, Maca has the effect that strengthens energy, resisting fatigue, improves sexual function.By it is combined with toothpaste, Maca dentifrice composition of the present invention not only has the intraoral food debris of cleaning, the dirt of teeth surfaces, maintain the common effect of toothpaste such as ph balancing in oral cavity, the functional components that can also retain to the maximum limit Maca, obtains allaying tiredness, strengthens energy, improves the multiple bonus effects such as sexual function.Toothpaste of the prior art is mainly paid close attention to cleaning oral cavity or solution and tooth, problem or disease that oral cavity is relevant, at present not yet find to have the tooth paste product of the functions such as resisting fatigue, do not find to using plant component/extract tooth paste product as anti-fatigue active composition in toothpaste.Therefore, Maca dentifrice composition of the present invention has certain initiative in oral care implement field.
2. Maca dentifrice composition of the present invention can make the active component of Maca directly absorb by sublingual vein, reduced due to the destruction of gastrointestinal enzyme regulating liver-QI enzyme to active component, correspondingly improved the degree of absorbing of Maca active substance, can obtain better function and improve effect.
3. in addition, Maca dentifrice composition of the present invention has increased the approach that people absorb Maca.Can no longer be confined to edible or be prepared as special preparation and carry out again orally, but just can obtain the health-care effect that Maca brings in daily mouth care.
The specific embodiment
Below by specific embodiment, further illustrate the present invention, still, should be understood to, these embodiment are only used for the use specifically describing more in detail, and should not be construed as for limiting in any form the present invention.
General description is carried out to the material and the test method that use in the present invention's test in this part.Although be well known in the art for realizing many materials and the operational approach that the object of the invention used, the present invention still does to describe in detail as far as possible at this.It will be apparent to those skilled in the art that in context, if not specified, material therefor of the present invention and operational approach are well known in the art.
embodiment 1
The present embodiment is used for illustrating Maca dentifrice composition of the present invention and preparation method thereof.
Formula:
| Composition | Percentage by weight |
| Water | 25% |
| Maca fecula | 1.5% |
| Sorbitol | 15% |
| Glycerol | 12% |
| Polyethylene Glycol | 5% |
| Saccharin sodium | 0.3% |
| Sodium monofluorophosphate | 0.8% |
| Sodium chloride | 0.1% |
| Calcium hydrogen phosphate | 38% |
| Oleum menthae | 1% |
| Tetrasodium pyrophosphate | 0.3% |
| Sodium lauryl sulfate | 1% |
Preparation process:
(1) make Maca fecula: take Maca as raw material, through steps such as section, dry, pulverizing, sterilizings, make Maca fecula standby.
(2) by formula, take each component of above-mentioned Maca fecula and toothpaste matrix, after mixing, stir 2h to evenly, standing, obtain described dentifrice composition.Then can carry out sterile filling and other packaging processes.
embodiment 2
The present embodiment is used for illustrating Maca dentifrice composition of the present invention and preparation method thereof.
Formula:
| Composition | Percentage by weight |
| Water | 33% |
| Maca dry extract | 1.2% |
| Sodium carboxymethyl cellulose | 0.3% |
| Sorbitol | 24.4% |
| Glycerol | 10% |
| Sodium hydroxide | 0.1% |
| Saccharin sodium | 0.2% |
| Sodium fluoride | 0.2% |
| Ethylene methacrylic ether | 1% |
| Titanium dioxide | 0.1% |
| Hydration Silicon stone | 20% |
| Siloxanes dioxide | 5% |
| Chinese cymbidium oil | 1% |
| Tetrasodium pyrophosphate | 1% |
| Phosphoric acid five sodium | 1.2% |
| Sodium lauryl sulfate | 1% |
| Cocamido propyl betaine | 0.3% |
Preparation process:
(1) make Maca dry extract: Maca tuber is dropped in circulating extraction container by hot reflux, soak, pass into Steam Heating reflux, extract,, almost colourless to extracting solution, collect extracting solution and filter, concentrate, spray dry and make.
(2) by formula, take each component of above-mentioned Maca fecula and toothpaste matrix, after mixing, stir 1h to evenly, standing, obtain described dentifrice composition.Then can carry out sterile filling and other packaging processes.
Test example 1 Evaluation on anti-fatigue effect
1. subject: adopt the method for completely random packet design, 60 experimenters are gesticulated to sequence by surname, by table of random number method, experimenter is divided into 3 groups: experimental group 1, experimental group 2 and matched group.Wherein, the toothpaste that experimental group 1 is used embodiment 1 to make, the toothpaste that experimental group 2 is used embodiment 2 to make, matched group is used blank toothpaste.
2. test method: experimenter uses same toothbrush and the toothpaste of above-mentioned appointment, requires to brush teeth 1 time by level vibration method, and at least 2 minutes, the lotion of toothpaste of use was about 1～1.5cm.Require not use other dental care products in process of the test.Diet is not restricted.
3. evaluation methodology: experimenter is respectively during 0,5,10,15,20 minute after brushing teeth, according to following table to the mental status from scoring, calculate every group in the scoring meansigma methods of each time point.
Table 1 mental status standards of grading
| The mental status is described | Score |
| Energetic | 7-10 |
| The mental status is good | 4-7 |
| Sleepy tired out | 0-4 |
Table 2 Evaluation on anti-fatigue effect result
Above experimental result shows, after using Maca dentifrice composition of the present invention, the obvious improvement of feeling the mental status in after brushing teeth 10 minutes of experimenter, and its effect can maintain 20 minutes or longer, illustrate that dentifrice composition of the present invention has lasting enhancing energy and the effect of resisting fatigue.
Although the present invention has carried out description to a certain degree, significantly, do not departing under the condition of the spirit and scope of the present invention, can carry out the suitable variation of each condition.Be appreciated that and the invention is not restricted to described embodiment, and be attributed to the scope of claim, it comprises the replacement that is equal to of described each factor.
Claims (8)
1. a Maca dentifrice composition, this dentifrice composition comprises toothpaste matrix, it is characterized in that, and described dentifrice composition also comprises Maca fecula and/or Maca dry extract.
2. dentifrice composition according to claim 1, is characterized in that, Maca fecula and/or Maca dry extract account for 0.1～10wt.% of described dentifrice composition gross weight, are preferably 0.5～5wt.%, more preferably 1～2wt.%.
3. dentifrice composition according to claim 1 and 2, is characterized in that, described Maca fecula is to take Maca as raw material, after section, dry, pulverizing, sterilizing, makes; Described Maca dry extract is that Maca tuber is dropped in circulating extraction container by hot reflux, soaks, and passes into Steam Heating reflux, extract,, almost colourless to extracting solution, collects extracting solution and filters, concentrates, sprays dry and make.
4. according to the dentifrice composition described in any one in claims 1 to 3, it is characterized in that, described toothpaste matrix comprises abrasivus, thickening agent, wetting agent and surfactant; Preferably, in described dentifrice composition, described abrasivus accounts for 10～50wt.%, and described thickening agent accounts for 0.1～5wt.%, and described wetting agent accounts for 10～35wt.%, and described surfactant accounts for 0.01～5wt.%.
5. according to the dentifrice composition described in any one in claim 1 to 4, it is characterized in that, described toothpaste matrix also comprises one or more in sweeting agent, antiseptic, coloring agent and fumet; Preferably, at described dentifrice composition, described sweeting agent accounts for 0.1～10wt.%, and described antiseptic accounts for 0.1～1wt.%, and described coloring agent accounts for 0.01～1wt.%, and described fumet accounts for 1～5wt.%.
6. according to the dentifrice composition described in claim 4 or 5, it is characterized in that, described abrasivus is selected from one or more in calcium hydrogen phosphate, dicalcium phosphate dihydrate, dalcium biphosphate, calcium carbonate, calcium pyrophosphate, tetrasodium pyrophosphate, aluminium hydroxide, aluminium oxide, magnesium carbonate, magnesium phosphate, insoluble Polymeric sodium metaphosphate., insoluble potassium metaphosphate, titanium oxide, silicon dioxide, moisture silicic acid, hydration Silicon stone, titanium silicate, Zirconium orthosilicate. and synthetic resin abrasivus; Described thickening agent is selected from one or more in carrageenin, sodium carboxymethyl cellulose, methylcellulose, ethyl cellulose, cellulose acetate, ethyl cellulose sodium, sodium alginate, cluck xanthan, tragakanta, karaya, arabia gum, locust bean gum, polyvinyl alcohol, sodium polyacrylate, carboxy vinyl polymer, polyvinyl pyrrolidone, card pool ripple resin, silica gel, aluminum silica gel, thickening property silicon dioxide, Wei Gemu gel, artificial lithium magnesium silicate and xanthan gum; Described wetting agent is selected from one or more in glycerol, Sorbitol, ethylene glycol, propylene glycol, Polyethylene Glycol, polypropylene glycol, xylitol and maltose alcohol; Described surfactant is selected from one or more in anion surfactant, cationic surfactant, non-ionic surface active agent and zwitterionic surfactant; Described sweeting agent is selected from one or more in saccharin sodium, stevioside, Stevia rebaudiana (Bertoni) Hemsl extract, p-met hoxycinnamic aldehyde, NHDC, perillartine, glycyrrhizin, Talin and aspartyl-phenylalanine methyl ester.
7. the method for the Maca dentifrice composition described in any one in preparation claim 1 to 6, is characterized in that, the method comprises and takes Maca fecula and/or Maca dry extract and toothpaste matrix, after mixing, stirs, standing, obtains described dentifrice composition; Preferably, the time of described stirring is 0.5～2h.
In claim 1 to 6 the Maca dentifrice composition described in any one or the Maca dentifrice composition that makes in accordance with the method for claim 7 for the preparation of fatigue alleviating, strengthen energy or improve the application in health product, food or the medicine of sexual function.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104397710A (en) * | 2014-12-12 | 2015-03-11 | 香格里拉县天丽斯生物科技发展有限公司 | Composition capable of improving fatigue condition |
| CN105362118A (en) * | 2015-07-14 | 2016-03-02 | 武汉华士特工业生物技术开发有限公司 | Maca health-care toothpaste and preparation method |
| CN107041859A (en) * | 2017-03-01 | 2017-08-15 | 广东金山百草健康产业有限公司 | A kind of formula of beautiful millettia root toothpaste |
| CN109475472A (en) * | 2015-12-29 | 2019-03-15 | 莱雅公司 | Stable antioxidant composition |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050036954A1 (en) * | 2003-08-12 | 2005-02-17 | Arthur Zuckerman | Combination of toothpaste, a chemical agent and natural herbs for improving sexual performance |
-
2013
- 2013-10-16 CN CN201310482787.5A patent/CN103520044A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050036954A1 (en) * | 2003-08-12 | 2005-02-17 | Arthur Zuckerman | Combination of toothpaste, a chemical agent and natural herbs for improving sexual performance |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104397710A (en) * | 2014-12-12 | 2015-03-11 | 香格里拉县天丽斯生物科技发展有限公司 | Composition capable of improving fatigue condition |
| CN105362118A (en) * | 2015-07-14 | 2016-03-02 | 武汉华士特工业生物技术开发有限公司 | Maca health-care toothpaste and preparation method |
| CN105362118B (en) * | 2015-07-14 | 2018-11-16 | 武汉华士特工业生物技术开发有限公司 | A kind of maca health-care toothpaste and preparation method |
| CN109475472A (en) * | 2015-12-29 | 2019-03-15 | 莱雅公司 | Stable antioxidant composition |
| CN109475472B (en) * | 2015-12-29 | 2021-10-29 | 莱雅公司 | Stable antioxidant composition |
| CN107041859A (en) * | 2017-03-01 | 2017-08-15 | 广东金山百草健康产业有限公司 | A kind of formula of beautiful millettia root toothpaste |
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Application publication date: 20140122 |