CN103494962B - Traditional Chinese medicine composition capable of clearing heat and detoxifying - Google Patents
Traditional Chinese medicine composition capable of clearing heat and detoxifying Download PDFInfo
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- CN103494962B CN103494962B CN201310407930.4A CN201310407930A CN103494962B CN 103494962 B CN103494962 B CN 103494962B CN 201310407930 A CN201310407930 A CN 201310407930A CN 103494962 B CN103494962 B CN 103494962B
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Abstract
A traditional Chinese medicine composition capable of clearing heat and detoxifying relates to the technical field of Chinese herbal medicines, and is a medicament prepared from the following bulk drugs in parts by weight: 11-13 parts of dictamnusdasycarpusturcz, 9-11 parts of forsythia suspense, 29-31 parts of raw rehmannia root, 9-11 parts of lithospermum, 9-11 parts of cortex moutan, 11-13 parts of radix scrophulariae, 8-10 parts of cimicifugafoetida, 8-10 parts of coptis, 9-11 parts of radix codonopsis, 9-11 parts of cordatehouttuynia, 9-11 parts of viola yedoensismakino and 9-11 parts of clerodendroncyrtophyllumturcz. The traditional Chinese medicine composition is accord with traditional Chinese medicine syndrome differentiation theory on traditional Chinese medicinal material selection and compatibility; the traditional Chinese medicine composition is capable of dispersing wind-heat and clearing heat and detoxifying; and the traditional Chinese medicine composition has the advantages of easily-bought raw materials, simple preparation method, fast effectiveness and high cure rate.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition of heat-clearing and toxic substances removing.
Background technology
Heat-clearing and toxic substances removing, one of clearing away heat method.Be applicable to the method for the treatment of of pestilence, warm poison and multiple pyretic toxicity disease or skin infection furunculosis.Cure mainly: major part temperature.Fever with aversion to cold, women's head-ornaments redness lifts pain, and order can not be opened, discomfort in the throat, and dryness of the tongue is thirsty, red tongue with yellow fur, and rapid pulse is strong.Modern times are mainly used in facial erysipelas, mumps, epidemic hemorrhagic fever, acute tonsillitis, upper respiratory tract infection, acute suppurative otitis media, acute lymphadenitis, and it is patient that the card such as herpes zoster belongs to wind heat poison heresy.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of effective, the Chinese medicine composition of safe and reliable heat-clearing and toxic substances removing.
Technical problem to be solved by this invention realizes by the following technical solutions:
A Chinese medicine composition for heat-clearing and toxic substances removing, the medicament be made up of the crude drug of following weight portion,
Cortex Dictamni 11-13 part, Fructus Forsythiae 9-11 part, Radix Rehmanniae 29-31 part, Radix Arnebiae (Radix Lithospermi) 9-11 part, Cortex Moutan 9-11 part, Radix Scrophulariae 11-13 part, Rhizoma Cimicifugae 8-10 part, Rhizoma Coptidis 8-10 part, Radix Codonopsis 9-11 part, Herba Houttuyniae 9-11 part, Herba Violae 9-11 part, Radix Clerodenri Cyrtophylli 9-11 part.
Preferred weight part of each crude drug is:
Cortex Dictamni 12 parts, Fructus Forsythiae 10 parts, Radix Rehmanniae 30 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Cortex Moutan 10 parts, Radix Scrophulariae 12 parts, Rhizoma Cimicifugae 9 parts, Rhizoma Coptidis 9 parts, Radix Codonopsis 10 parts, Herba Houttuyniae 10 parts, Herba Violae 10 parts, Radix Clerodenri Cyrtophylli 10 parts.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Another object of the present invention is to provide a kind of method preparing the present composition, comprises the steps,
1) each crude drug is taken by following parts by weight;
2) above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 30 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.
1, pharmacology analysis:
Cortex Dictamni: bitter; Salty; Cold.Heat clearing and damp drying; Dispelling wind for relieving itching; Removing toxic substances.
Fructus Forsythiae: bitter, is slightly cold.Return lung, the heart, gallbladder meridian.Cure mainly calentura from the beginning of, anemopyretic cold, heating, vexed, laryngopharynx swelling and pain, acute nephritis etc.
Radix Rehmanniae: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.
Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.Hemorrhage; Blood-cooling drugs; Heat and toxic materials clearing away medicine.
Cortex Moutan: cold nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.
Radix Scrophulariae: sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
Rhizoma Cimicifugae: pungent, micro-sweet, is slightly cold.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.
Rhizoma Coptidis: bitter, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.
Radix Codonopsis: invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.
Herba Houttuyniae: cold nature, bitter in the mouth.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.
Herba Violae: bitter, acrid, cold is nontoxic; GUIXIN, Liver Channel.Be used as medicine, its mildly bitter flavor cold in nature, heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.
Radix Clerodenri Cyrtophylli: have heat clearing away, removing toxic substances, dispels the wind, the effects such as dehumidifying.
2, usage and consumption:
The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as the age of patient, body weight, health status.Instruction: decoction: 180-200ml, one day 2 times, sub-service sooner or later 3 days is a course for the treatment of.
3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to decoction prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 10, hungry 20 hours, fill with for 5 times by every only every natural gift and feed 50ml, feed one week continuously, observe 10 days, mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to decoction prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, feed by filling with for 2 times every every day, each 5-10ml is not etc., 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
4, diagnostic criteria
1) clinical diagnosis: heating, dryness of the tongue is thirsty, tonsillitis, the symptoms such as upper respiratory tract infection.
2) in order to verify clinical efficacy, this prescription is tried out in Affiliated Hospital of Chinese medicine institute first of Anhui Province respectively, and random selecting is 50 routine patients wherein.
3) Therapeutic Method: according to drug ratios of the present invention, takes raw material (dose) and decocts, every day 2 times, a 180-200ml, and a point morning and evening takes, and within 3 days, is a course for the treatment of, the shortest 1 course for the treatment of, the longest 5 courses for the treatment of.
4) efficacy determination:
Recovery from illness: sign and symptom are improved completely, happy, in high spirits; Effective: sign and symptom are significantly improved, happy, spirit very well; Effective: sign and symptom change, random thoughts are slightly uncomfortable, but can accept; Invalid: to treat rear symptom, sign compared with before treatment without any change; Concrete therapeutic outcome is see table 1.
Table 1
| Number of cases | Recovery from illness | Effective | Effectively | Invalid | Effective percentage (%) |
| 50 | 15 | 30 | 3 | 2 | 96 |
5, points for attention:
1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.
2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.
3. driver, work high above the ground person are cautious use of.
4. strictly take by usage and dosage, this medicine should not be taken for a long time in a large number.
5. pair this medicine and alcohol intolerance person forbidding, allergic constitution person be cautious use of.
6. prohibit the use when this property of drug changes.
7. please this medicine is placed on the place that child can not contact.
8. as used other medicines, please Ref Dr or pharmacist before using this medicine.
The invention has the beneficial effects as follows: the present invention selects at Chinese crude drug and compatibility meets Chinese medical discrimination theory, dispelling wind and heat pathogens, heat-clearing and toxic substances removing, and raw material is easily purchased, and compound method is simple, and have rapid-action, cure rate is high.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Each crude drug is taken: Cortex Dictamni 12g, Fructus Forsythiae 10g, Radix Rehmanniae 30g, Radix Arnebiae (Radix Lithospermi) 10g, Cortex Moutan 10g, Radix Scrophulariae 12g, Rhizoma Cimicifugae 9g, Rhizoma Coptidis 9g, Radix Codonopsis 10g, Herba Houttuyniae 10g, Herba Violae 10g, Radix Clerodenri Cyrtophylli 10g by following parts by weight.Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 30 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction, twice sub-service in a day.
Embodiment 2
Each crude drug is taken: Cortex Dictamni 11g, Fructus Forsythiae 9g, Radix Rehmanniae 29g, Radix Arnebiae (Radix Lithospermi) 9g, Cortex Moutan 9g, Radix Scrophulariae 11g, Rhizoma Cimicifugae 8g, Rhizoma Coptidis 8g, Radix Codonopsis 9g, Herba Houttuyniae 9g, Herba Violae 9g, Radix Clerodenri Cyrtophylli 9g by following parts by weight.Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 30 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction, twice sub-service in a day.
Embodiment 3
Each crude drug is taken: Cortex Dictamni 13g, Fructus Forsythiae 11g, Radix Rehmanniae 31g, Radix Arnebiae (Radix Lithospermi) 11g, Cortex Moutan 11g, Radix Scrophulariae 13g, Rhizoma Cimicifugae 10g, Rhizoma Coptidis 10g, Radix Codonopsis 11g, Herba Houttuyniae 11g, Herba Violae 11g, Radix Clerodenri Cyrtophylli 11g by following parts by weight.Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 30 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction, twice sub-service in a day.
Model case:
Case 1
Neat certain, female, 30 years old, company personnel, Anhui Province Fuyang City people.Patient is vexed, and dryness of the tongue is thirsty, urinates and does not relax, and falls when rising during seat skin ulcer.Dark tongue quality, red tip of the tongue, greasy and thin fur, the left string of arteries and veins is right heavy.Dialectical: strongly fragrant in pyretic toxicity, qi-blood disharmony.After taking 2 courses for the treatment of of prescription of the present invention, patient sends out acne without new, and urinate smooth, continue to take two courses for the treatment of of the present invention, symptom all disappears, recovery from illness.
Case 2
Leaf so-and-so, man, 45 years old, individual enterprise boss, people from Linquan County, Anhui Province.Heating more than ten skies, the red bleb of head, lip Zhou Duofa is examined, and red tongue falls, yellow fur, thready and rapid pulse.Take 2 courses for the treatment of of prescription of the present invention, patients symptomatic disappears, after take again 2 courses for the treatment of and consolidated, recovery from illness.
Case 3
Huang, man, 52 years old, peasant, Jin stockaded village, Jieshou City, Anhui Province village people.Suffer from acute tonsillitis and upper respiratory tract infection, after taking 1 course for the treatment of of prescription of the present invention, symptom alleviates, after taken again 2 courses for the treatment of, symptom all disappears, recovery from illness.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (5)
1. a Chinese medicine composition for heat-clearing and toxic substances removing, is characterized in that: the medicament be made up of the crude drug of following weight portion,
Cortex Dictamni 11-13 part, Fructus Forsythiae 9-11 part, Radix Rehmanniae 29-31 part, Radix Arnebiae (Radix Lithospermi) 9-11 part, Cortex Moutan 9-11 part, Radix Scrophulariae 11-13 part, Rhizoma Cimicifugae 8-10 part, Rhizoma Coptidis 8-10 part, Radix Codonopsis 9-11 part, Herba Houttuyniae 9-11 part, Herba Violae 9-11 part, Radix Clerodenri Cyrtophylli 9-11 part.
2. the Chinese medicine composition of a kind of heat-clearing and toxic substances removing according to claim 1, is characterized in that: the medicament be made up of the crude drug of following weight portion,
Cortex Dictamni 12 parts, Fructus Forsythiae 10 parts, Radix Rehmanniae 30 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Cortex Moutan 10 parts, Radix Scrophulariae 12 parts, Rhizoma Cimicifugae 9 parts, Rhizoma Coptidis 9 parts, Radix Codonopsis 10 parts, Herba Houttuyniae 10 parts, Herba Violae 10 parts, Radix Clerodenri Cyrtophylli 10 parts.
3. the Chinese medicine composition of a kind of heat-clearing and toxic substances removing according to claim 1, is characterized in that: described preparation is oral formulations.
4. the Chinese medicine composition of a kind of heat-clearing and toxic substances removing according to claim 3, is characterized in that: described oral formulations is decoction.
5. prepare a method for Chinese medicine composition described in any one of claim 1 or 2, it is characterized in that: comprise the following steps,
1) each crude drug is taken by prescription parts by weight;
2) above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 30 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.
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| CN103721007A (en) * | 2014-01-15 | 2014-04-16 | 李茂林 | Traditional Chinese medicament for treating neonatal erythema toxicum and preparation method thereof |
| CN103816300B (en) * | 2014-01-21 | 2017-09-22 | 中国人民解放军***联勤部药品仪器检验所 | A kind of medicinal herb spray for treating skin disorder or mucous membrane cavity illness |
| CN103893385A (en) * | 2014-03-14 | 2014-07-02 | 于波 | Traditional Chinese medicine for clearing away heat and toxic materials |
| CN104305196A (en) * | 2014-10-27 | 2015-01-28 | 陈国勇 | Composition for clearing heat and cooling blood and preparation method thereof |
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| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101810800A (en) * | 2010-05-26 | 2010-08-25 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating skin itch and preparation method thereof |
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Patent Citations (3)
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|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101810800A (en) * | 2010-05-26 | 2010-08-25 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating skin itch and preparation method thereof |
| CN102772555A (en) * | 2012-07-30 | 2012-11-14 | 李承平 | Golden flower detoxicatcating tablet |
Non-Patent Citations (2)
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Effective date of registration: 20181113 Address after: 201315 Room 301, building A1, 2388 Xiu Pu Road, Pudong New Area, Shanghai. Patentee after: SHANGHAI MINGHONG BIOENGINEERING CO., LTD. Address before: 236508 5 Xu Si administrative village, Guang Wu Town, Jieshou City, Fuyang, Anhui Patentee before: Xu Ruyang |
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