CN103480077A - Guide wire - Google Patents

Guide wire Download PDF

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Publication number
CN103480077A
CN103480077A CN201310376208.9A CN201310376208A CN103480077A CN 103480077 A CN103480077 A CN 103480077A CN 201310376208 A CN201310376208 A CN 201310376208A CN 103480077 A CN103480077 A CN 103480077A
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China
Prior art keywords
seal wire
guide seal
mid portion
connecting portion
guide
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Pending
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CN201310376208.9A
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Chinese (zh)
Inventor
谷村哲明
谷村麻欧
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Individual
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Individual
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Priority to CN201310376208.9A priority Critical patent/CN103480077A/en
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Abstract

The invention provides a guide wire, comprising a first part, a middle part, a connection part and an end part, wherein the middle part is made of an optical transparent material or semitransparent material, and one end of the middle part is connected with one end of the first part; one end of the connection part is connected with the other end of the middle part; the end part is connected to the other end of the connection part, and is used for guiding the entering of the whole guide wire; the first part, the middle part, the connection part and the end part are connected in sequence, and the whole guide wire has flexibility.

Description

Guide seal wire
Technical field
The present invention relates to a kind of medical guide seal wire, more specifically, the present invention relates to a kind of optical clear for the systemic arterial vascular interventional treatment or translucent guide seal wire.
Background technology
In recent years, fast development due to interventional therapeutic techniques such as vascular lesion, cardiac stents, the requirement of the guiding seal wire that makes the laser irradiation (PDT) during optical fault scanning imagery art (OCT) field, optical power are treated or use in the fluorescent antibody detection method of the macrophage for detection of whole blood vessel wall is more and more higher, because during arteries pathological changes at the observation whole body everywhere, the scope of observing larger (the imaging blind area is fewer) is observed clearlyer, so just more helpful for diagnosis, the treatment of the state of an illness.
In addition, take Percutaneous Coronary Intervention as example, due to the updating and develop of coronary intervention apparatus, make in the past the interventional therapy chronic occlusion of difficulty relatively; Serious calcification; The coronary artery pathological changes of the complexity such as distortion, angulation has become possibility by interventional therapy, and has obtained higher success rate of operation, for vast patients with coronary heart disease brings huge benifit.Guiding wire, as the basic platform of coronary intervention, plays a part very important in whole coronary intervention process.
But in the prior art,, for example, when carrying out the OCT imaging, because the OCT camera lens can often be biased due to the wriggling of blood vessel etc., so, when camera lens is taken from the seal wire top, can easily cause very large imaging blind area, blind area even can reach 45 ° to 90 ° sometimes.This for pathological changes observe, the diagnosis state of an illness etc. is very fatal defect aspect, can produce very large error or for avoiding error to carry out the Multiple-Scan imaging with regard to same position.Usually, in order addressing this problem, can to need to take out and reinsert seal wire, to re-start shooting.Like this, not only can cause the damage of blood vessel wall, cause that acute occlusion or thrombosis come off etc., also can bring more misery for the patient, and can produce very high expense, and the wasting manpower and material resources.
Although disclose in the prior art the imaging catheter of some seal wires or partially transparent, there is no to disclose the guide seal wire that itself there is transparent or semitransparent part in prior art.By, although prior art also discloses the imaging catheter of partially transparent, the optical catheter that a kind of OCT uses is for example disclosed in WO03051184A1, this optical catheter comprises optical fibers and holds fibre-optic quill shaft, have a plurality of transparent or semitransparent windows or aperture on this quill shaft, thereby optical fibers can rotate near window or aperture optical scanning is provided in quill shaft, but this guide seal wire is because the limitation in window or aperture can not make the blind area of OCT scanning imagery minimize, and complex structure.
In the existing serial seal wire of for example being produced by Asahi Intecc company or Abbott Laboratories company in this area, do not there is optical clear or translucent portion, therefore these seal wires are when the guide instrument camera lens is observed blood vessel wall, especially in the situation that seal wire extend into the arteries end, capital has very large blind area (blind area can up to 90 °), is unfavorable for very much diagnosis and the treatment of the state of an illness.
Therefore, in the urgent need to not affected guide seal wires such as optical signalling that a kind of optical diagnostics that can keep optical clear, guarantee to relate to blood vessel wall, treatment, imaging are provided, exposure rates.
Summary of the invention
For overcome set forth above existing defective at least one, the optical signalling, exposure rate etc. that can keep the seal wire optical clear and guarantee to relate to optical diagnostics, treatment, the imaging of blood vessel wall are not affected, the blind area of observing is minimized, the present invention proposes a kind of optical clear or translucent guide seal wire, described guide seal wire comprises: first; Mid portion, described mid portion is made by optical clear or trnaslucent materials, and an end of described mid portion is connected with an end of described first; Connecting portion, an end of described connecting portion is connected with the other end of described mid portion; With the tip part, described tip partly is connected to the other end of described connecting portion, and for guiding entering of whole guide seal wire, wherein said first, mid portion, connecting portion, tip part sequentially connect, and its integral body has flexibility.
Preferably, mid portion engages with an end of described first and an end of described connecting portion respectively by gluing or bonding mode, and is clamped between described first and described connecting portion.
Preferably, mid portion is made by transparent plastic or fibre-optic bundle, one end of described mid portion and the other end have respectively can fastening described transparent plastic or the tight loop of fibre-optic bundle, described tight loop is connected respectively to an end of described first and an end of described connecting portion, thereby, in the time of in described guide seal wire is directed to position to be imaged, described mid portion can not be out of shape.
Preferably, fibre-optic bundle is comprised of 50-200 root optical fibers, and every fibre-optic diameter is 20-100 μ m.
Preferably, mid portion has the core of rustless steel thin slice or cylindrical form, and described core and described first and described connecting portion are made into integration, and transparent plastic or optical clear or translucent polymer silk are wrapped in the outside of described core spirally.
Preferably, the core with rustless steel thin slice form has flat pattern, and its width is 0.05mm to 0.10mm, and its thickness is 0.025mm to 0.05mm; Diameter with core of cylinder form is 0.10mm.
Preferably, the length of described mid portion is 300mm to 800mm, thereby guarantees that, when seal wire extend in position to be imaged, there is not the opaque situation of optics in the seal wire at described position to be imaged.
Preferably, described first and described connecting portion consist of the medical stainless steel silk, and wherein said optical clear or trnaslucent materials comprise medical quartz, glass, plastics or polymer; Preferably, described optical clear or trnaslucent materials comprise acrylic resin or CR-39 plastic polymer.
Preferably, described acra is divided and is comprised steel wire or heart yearn, is wrapped in the coiling silk of described steel wire or heart yearn outside and is arranged on the sharp distal tip of end, and described tip partly has flexibility, thereby can guide entering of described guide seal wire.
Preferably, the entire outer diameter of described guide seal wire is 0.25mm, 0.36mm or 0.46mm.
Other side of the present invention and/or advantage part are in the following description set forth, and will from described explanation, partly know and present, or can in to practice of the present invention, learn.
The accompanying drawing explanation
Will be from the explanation of following embodiment, with reference to accompanying drawing, make these and/or other side of exemplary embodiments of the present invention and advantage become more apparent and be easier to understand, wherein:
Fig. 1 shows the schematic diagram of the first embodiment of transparent or semitransparent guide seal wire of the present invention.
Fig. 2 A shows the schematic diagram of the second embodiment of transparent or semitransparent guide seal wire of the present invention.
Fig. 2 B shows the sectional view of the guide seal wire shown in Fig. 2 A.
Fig. 3 A is the structural representation of a kind of embodiment of the mid portion of the guide seal wire in Fig. 2 A.
Fig. 3 B is the structural representation of another kind of embodiment of the mid portion of the guide seal wire in Fig. 2 A.
Fig. 4 shows the schematic diagram of the 3rd embodiment of transparent or semitransparent guide seal wire of the present invention.
Fig. 5 A has shown that while utilizing guide seal wire of the present invention to carry out imaging, camera lens irradiates the blind area schematic diagram produced at the blood vessel wall top, and wherein dash area means the irradiation blind area of blood vessel wall.
Fig. 5 B has shown that while utilizing guide seal wire of the present invention to carry out imaging, the blind area schematic diagram produced is irradiated at camera lens place in the middle of blood vessel, and wherein dash area means the irradiation blind area of blood vessel wall.
Fig. 5 C has shown that while utilizing guide seal wire of the present invention to carry out imaging, camera lens irradiates in the blood vessel wall bottom blind area schematic diagram produced, and wherein dash area means the irradiation blind area of blood vessel wall.
Fig. 6 A has shown that when the guide seal wire that utilizes prior art carries out imaging, camera lens irradiates the blind area schematic diagram produced at the blood vessel wall top, and wherein dash area means the irradiation blind area of blood vessel wall.
Fig. 6 B has shown that when the guide seal wire that utilizes prior art carries out imaging, the blind area schematic diagram produced is irradiated at camera lens place in the middle of blood vessel, and wherein dash area means the irradiation blind area of blood vessel wall.
Fig. 6 C has shown that when the guide seal wire that utilizes prior art carries out imaging, camera lens irradiates in the blood vessel wall bottom blind area schematic diagram produced, and wherein dash area means the irradiation blind area of blood vessel wall.
The specific embodiment
Below in conjunction with the drawings and specific embodiments, transparent or semitransparent guide seal wire provided by the invention is described in detail.
Fig. 1 shows the first embodiment of transparent or semitransparent guide seal wire of the present invention.Guide seal wire 10 to comprise first 11, mid portion 12, connecting portion 13 and tip part 14.First 11, mid portion 12, connecting portion 13 and tip part 14 be being linked in sequence from left to right as shown in fig. 1, and wherein mid portion 12 firmly is clamped between first 11 and connecting portion 13.
Connecting portion 13 is connected between mid portion 12 and tip part 14, for playing the transitional function that is transitioned into tip part 14 from middle part 12.The length of connecting portion 13 can be 10mm.
For guiding the tip part 14 of whole guide seal wire to comprise: the wind spring 142 and the sharp distal tip 143 that there is flexible steel wire or heart yearn 141, reel outside steel wire or heart yearn, and tip part 14 integral body all have flexibility, thereby the convenient shape of blood vessel that coordinates guides entering of whole guide seal wire.
In the first embodiment shown in Fig. 1, mid portion 12 is integral structures of being made by optical clear or trnaslucent materials integral body.The one end is connected or interface with an end of first, and its other end is connected or interface with an end of connecting portion.Like this, mid portion 12 can firmly be clamped between first 11 and connecting portion 13.In the present embodiment, can mid portion be clamped between first and connecting portion by gummed and bonding mode.Certainly, the invention is not restricted to this, also can mid portion be clamped between first and connecting portion by alternate manner.
First 11, connecting portion 13 and whole tip part 14 are all to consist of the medical stainless steel silk such as SUS306L or SUS304L.
And form the optical clear of mid portion or trnaslucent materials comprise have good transmitance can medical quartz, glass, plastics or polymer etc., such as acrylic resin or for the CR-39 plastic polymer of making contact lens etc.
Mid portion 12 can be optical clear or translucent, like this, at the light source of camera lens, PDT laser irradiating part or the fluorescent antibody checkout gear of for example OCT imaging device when irradiating blood vessel above seal wire, the optical characteristics of mid portion allows to arrive blood vessel wall to be seen from the light transmission of light source through this part, thereby obtains the image needed.
The length of mid portion 12 can be 300mm to 800mm, and wherein 800mm is arterial vascular extreme length.Like this, can guarantee that mid portion can insert arterial vascular whole length to be seen when work.Therefore, when operation, can guarantee that the whole seal wire part of inserting in blood vessel is all optical clear or translucent, thereby the blind area of scanning imagery is minimized.
Therefore, for the blind area (as shown in Fig. 6 A-6C) of 45 °-90 ° of traditional seal wire, the blind area that the camera lens of the optical clear of the application of the invention or the guiding of translucent seal wire OCT, PDT etc. causes while carrying out imaging can be minimized, be preferably between 0-15 °, as shown in Fig. 5 A-5C, thereby greatly improved OCT scanning imagery, the imaging of PDT Infrared irradiation or utilized the fluorescent antibody detection method to detect accuracy and the efficiency of intravascular macrophage.
Introduce below with reference to Fig. 2 A-3B the second embodiment that the present invention guides the mid portion of seal wire, in a second embodiment, all the front face is described same or similar for first, connecting portion and tip part, so its details will repeat no more.
As shown in Figure 2 A, similar to the embodiment shown in Fig. 1, optical clear or translucent seal wire 20 comprise the first be linked in sequence 21 from left to right, mid portion 22, connecting portion 23 and tip part 24 as shown in Figure 2A and 2B.
The difference of embodiment shown in this embodiment and Fig. 1 is, as shown in Fig. 2 B, mid portion 22 comprises core 221 and is wrapped in spirally the wound portion 222 of core outside.Core 221 can form with first 21 and connecting portion 23 one, and its prepare material also with first and connecting portion to prepare material identical, be all to be made by medical stainless steel.Wound portion 222 is wound on core 221 outsides spirally, and consists of the essentially identical material of material of the mid portion 12 of the guide seal wire 10 with shown in pie graph 1, thereby has good transmitance.
As shown in Fig. 3 A and 3B, core can have sheet and shreds belt shape or cylindrical shape, and wherein the width of sheet and shreds band core is 0.05-0.10mm, and thickness is 0.025-0.05mm, and the diameter of cylinder core is 0.10mm.When use has the translucent guide seal wire of mid portion of core of sheet and shreds belt shape, need to control the orientation of mid portion well by the operator, thereby make the projected area minimum of mid portion when camera lens scanning or imaging, make thus the blind area of scanning imagery minimize.
The length of mid portion 22 can be 300mm to 800mm, and wherein 800mm is arterial vascular extreme length.Like this, can guarantee that mid portion can insert arterial vascular whole length to be seen when work.Therefore, when operation, can guarantee that the whole seal wire part of inserting in blood vessel is all that optics is translucent, thereby the blind area of scanning imagery is minimized.
Fig. 4 shows the another embodiment of guide seal wire of the present invention.As shown in Figure 4, similar to the embodiment shown in Fig. 1, optical clear or translucent seal wire 30 comprise as shown in Figure 2A and 2B the first be linked in sequence 31, mid portion 32, connecting portion 33 and tip part 34 from left to right.
The difference of embodiment shown in this embodiment and Fig. 1 is, mid portion 32 can be made by transparent plastic or optical fibers or transparent plastic bundle or fibre-optic bundle.The two ends of mid portion 32 fastened circle respectively are fixed together, and with an end of first 31 and an end of connecting portion 33, are connected respectively by this tight loop, thereby mid portion can firmly be clamped between first and connecting portion.Fibre-optic bundle is comprised of 50-200 root optical fibers, and every fibre-optic diameter is preferably 20-100 μ m.
No matter be the guide seal wire of which kind of embodiment, the entire outer diameter of its several parts is all consistent, all has the standard size of this area, for example 0.25mm, 0.36mm or 0.46mm.
The contrast of the blood vessel blind area that next, explanation is used guide seal wire of the present invention and do not used guide seal wire of the present invention to produce with reference to Fig. 5 A-6C.
Fig. 5 A-5C shows camera lens while utilizing guide seal wire of the present invention to carry out imaging and irradiates at the different parts (top, centre, bottom) of blood vessel the blind area schematic diagram produced, and wherein dash area means the irradiation blind area of blood vessel wall.Fig. 6 A-6C shows the guide seal wire that utilizes prior art accordingly while carrying out imaging, and camera lens irradiates at the different parts of blood vessel the blind area schematic diagram produced, and wherein dash area means the irradiation blind area of blood vessel wall.From two picture groups, can obviously find out, the blood vessel blind area produced while using guide seal wire of the present invention to scan irradiation (approximately 0-15 ° of left and right) is far smaller than the guide seal wire that uses prior art and scans the blood vessel blind area (approximately 45-90 °) produced while irradiating.Therefore, the blood vessel blind area of having used guide seal wire of the present invention to reduce widely even to have eliminated scanning to irradiate, greatly improved efficiency and the accuracy of optical diagnostics, treatment.
Guide seal wire of the present invention can be used for observing, diagnosing and treat the pathological changes of the systemic arterial blood vessel that comprises cerebral arteries, carotid artery, heart coronary artery, large artery trunks, bone tremulous pulse, femoral artery etc.Utilize that guide seal wire of the present invention can to keep whole insertion portion be all optical clear or translucent in the situation that seal wire inserts the arteries end, thereby guarantee that optical signalling, the exposure rate of optical diagnostics, treatment, imaging etc. are not subject to or are affected hardly.
Finally it should be noted that, above embodiment is only in order to describe technical scheme of the present invention rather than the present technique method is limited, the present invention can extend to other modification, variation, application and embodiment in application, and therefore thinks that all such modifications, variation, application, embodiment are in spirit of the present invention and teachings.

Claims (10)

1. one kind is guided seal wire, and described guide seal wire comprises:
First;
Mid portion, described mid portion is made by optical clear or trnaslucent materials, and an end of described mid portion is connected with an end of described first;
Connecting portion, an end of described connecting portion is connected with the other end of described mid portion; With
The tip part, described tip partly is connected to the other end of described connecting portion, for guiding entering of whole guide seal wire,
Wherein said first, mid portion, connecting portion, tip part sequentially connect, and its integral body has flexibility.
2. guide seal wire according to claim 1, wherein said mid portion engages with an end of described first and an end of described connecting portion respectively by gluing or bonding mode, and is clamped between described first and described connecting portion.
3. guide seal wire according to claim 1, wherein said mid portion is made by transparent plastic, optical fibers or fibre-optic bundle, one end of described mid portion and the other end have respectively can fastening described transparent plastic or the tight loop of fibre-optic bundle, described tight loop is connected respectively to an end of described first and an end of described connecting portion, thereby, in the time of in described guide seal wire is directed to position to be imaged, described mid portion can not be out of shape.
4. guide seal wire according to claim 3, wherein said fibre-optic bundle is comprised of 50-200 root optical fibers, and every fibre-optic diameter is 20-100 μ m.
5. guide seal wire according to claim 1, wherein said mid portion has the core of rustless steel thin slice or cylindrical form, described core and described first and described connecting portion are made into integration, and transparent plastic or optical clear or translucent polymer silk are wrapped in the outside of described core spirally.
6. guide seal wire according to claim 5, the core that wherein has rustless steel thin slice form has flat pattern, and its width is 0.05mm to 0.10mm, and its thickness is 0.025mm to 0.05mm; Diameter with core of cylinder form is 0.10mm.
7. guide seal wire according to claim 1, the length of wherein said mid portion is 300mm to 800mm, thereby guarantees that, when seal wire extend in position to be imaged, there is not the opaque situation of optics in the seal wire at described position to be imaged.
8. guide seal wire according to claim 1, wherein said first and described connecting portion consist of the medical stainless steel silk, wherein said optical clear or trnaslucent materials comprise medical quartz, glass, plastics or polymer, preferably, described optical clear or trnaslucent materials comprise acrylic resin or CR-39 plastic polymer.
9. guide seal wire according to claim 1, wherein said acra is divided and is comprised steel wire or heart yearn, is wrapped in the coiling silk of described steel wire or heart yearn outside and is arranged on the sharp distal tip of end, described tip partly has flexibility, thereby can guide entering of described guide seal wire.
10. guide seal wire according to claim 1, the entire outer diameter of wherein said guide seal wire is 0.25mm, 0.36mm or 0.46mm.
CN201310376208.9A 2013-08-26 2013-08-26 Guide wire Pending CN103480077A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106846347A (en) * 2017-02-15 2017-06-13 深圳市中科微光医疗器械技术有限公司 Stenter to implant based on OCT preoperative analysis system and analysis method
CN107847716A (en) * 2015-11-17 2018-03-27 郡是株式会社 Medical guide wire
WO2018120451A1 (en) * 2016-12-28 2018-07-05 尚华 Vascular fiber optic guide wire
US10639496B2 (en) 2016-12-28 2020-05-05 Hua Shang Blood vessel optical fiber guide wire

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101217915A (en) * 2005-07-11 2008-07-09 科丰公司 Surgical access device, system, and methods of use
CN101360448A (en) * 2006-01-12 2009-02-04 明尼苏达医药发展股份有限公司 Conductive filament of titanium molybdenum alloy
CN101657161A (en) * 2007-05-03 2010-02-24 伊西康内外科公司 An anastomotic applier and method for performing endoluminal and/or transluminal anastomosis
CN103118583A (en) * 2010-09-24 2013-05-22 阿克拉伦特公司 Sinus illumination lightwire device
CN203469207U (en) * 2013-08-26 2014-03-12 谷村哲明 Guiding seal wire

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101217915A (en) * 2005-07-11 2008-07-09 科丰公司 Surgical access device, system, and methods of use
CN101360448A (en) * 2006-01-12 2009-02-04 明尼苏达医药发展股份有限公司 Conductive filament of titanium molybdenum alloy
CN101657161A (en) * 2007-05-03 2010-02-24 伊西康内外科公司 An anastomotic applier and method for performing endoluminal and/or transluminal anastomosis
CN103118583A (en) * 2010-09-24 2013-05-22 阿克拉伦特公司 Sinus illumination lightwire device
CN203469207U (en) * 2013-08-26 2014-03-12 谷村哲明 Guiding seal wire

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107847716A (en) * 2015-11-17 2018-03-27 郡是株式会社 Medical guide wire
CN107847716B (en) * 2015-11-17 2021-08-24 郡是株式会社 Medical guide wire
WO2018120451A1 (en) * 2016-12-28 2018-07-05 尚华 Vascular fiber optic guide wire
US10639496B2 (en) 2016-12-28 2020-05-05 Hua Shang Blood vessel optical fiber guide wire
CN106846347A (en) * 2017-02-15 2017-06-13 深圳市中科微光医疗器械技术有限公司 Stenter to implant based on OCT preoperative analysis system and analysis method

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Application publication date: 20140101