CN103479955A - Drug with function of reinforcing spleen to promote digestion - Google Patents
Drug with function of reinforcing spleen to promote digestion Download PDFInfo
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- CN103479955A CN103479955A CN201310462743.6A CN201310462743A CN103479955A CN 103479955 A CN103479955 A CN 103479955A CN 201310462743 A CN201310462743 A CN 201310462743A CN 103479955 A CN103479955 A CN 103479955A
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Abstract
The invention discloses a drug with the function of reinforcing spleen to promote digestion. The drug is medicament prepared by crude drugs in parts by weight as follows: 30 parts of raw radix astragali, 30 parts of Chinese yam, 15 parts of roasted rhizoma atractylodis macrocephalae, 30 parts of coix seeds, 10 parts of coptis roots, 30 parts of dandelion, 15 parts of Chinese angelica, 6 parts of honey-fried licorice roots, 20 parts of dendrobium, 15 parts of eucommia barks, 10 parts of baical skullcap roots, 15 parts of teasel roots, 15 parts of Indian breads, 10 parts of jade butterfly, 10 parts of cortex magnoliae officinalis, 10 parts of cassia twig, 30 parts of hairyvein agrimonia herb, 10 parts of fructus amomi, 15 parts of bletilla, 15 parts of white paeony roots, 15 parts of white lablab beans and 10 parts of immature bitter orange. The drug has an unexpected effect on reinforcing spleen to promote digestion.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specially a kind of medicine of strengthening the spleen to promote digestion.
Background technology
Insufficiency of the spleen dysfunction of the spleen in transportation and transformation, and malnutrition can occur, water liquid loses in spreading and gives birth to the wet expectorant of making, or the disease such as lose blood.Its disease is at stomach, and dyspepsia relates to the internal organs such as liver spleen, and suitable determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, give invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, the treatment of the methods such as dyspepsia and intestinal stasis relieving.But the western medicine side effect is larger, the Chinese patent medicine DeGrain that market is similar.
Summary of the invention
The objective of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, provides a kind of medicine of strengthening the spleen to promote digestion according to Chinese medical theory.
The medicine of strengthening the spleen to promote digestion of the present invention is the medicament of being made by the crude drug of following parts by weight:
15 parts of 30 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 10 parts of Fructus Aurantiis and Semen Lablab Albums.
Described medicament is capsule.
The preparation method of medicine of the present invention is:
Get by weight 30 parts of crude drug Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 10 parts of Fructus Aurantiis and 15 parts of Semen Lablab Albums standby;
Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.
Strengthening the spleen to promote digestion Chinese medicine composition provided by the invention, its raw material is Radix Astragali, Rhizoma Dioscoreae, Rhizoma Atractylodis Macrocephalae (parched), Semen Coicis, Rhizoma Coptidis, Herba Taraxaci, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata, Herba Dendrobii, the Cortex Eucommiae, Radix Scutellariae, Radix Dipsaci, Poria, Semen Oroxyli, Cortex Magnoliae Officinalis, Ramulus Cinnamomi, Herba Agrimoniae, Fructus Amomi, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, Fructus Aurantii and Semen Lablab Album, can be used for the vomiting that treatment causes because of insufficiency of the spleen and dyspepsia, abdominal distention and become thin etc., the effect with certain strengthening the spleen to promote digestion that above-mentioned medical material has, the effect with certain building body had, this formula is in R&D process, the formula of take in the patent of applying on the same day is core, the additional formula drawn by increase and decrease flavour of a drug and adjustment compatibility relationship, wherein Semen Lablab Album has the spleen reinforcing dehumidifying, Semen Coicis can the spleen reinforcing eliminating dampness by diuresis.Semen Lablab Album, Semen Coicis is compatible with this ratio, eliminating dampness and diuresis contributes to treatment to have loose bowels, hand over and make to have good action for vomiting and diarrhoea, and the Rhizoma Dioscoreae effect of reinforcing the kidney itself adds Rhizoma Dioscoreae and Semen Lablab Album to match as ministerial drug and monarch drug Semen Coicis, because after insufficiency of the spleen inability of food and drink to be digested and transported vital essence, there is water wet dirty, an astringency inducing be arranged.So and, after the above-mentioned raw materials medicine carries out the compatibility of rational proportion according to the combination principle of monarch, strengthened the spleen reinforcing exsiccation.Because Seem Lablab Album can removing dampness also can dampness removing, Semen Coicis beyond the spleen reinforcing, dampness removing is main.After carrying out the compatibility of rational proportion with the above-mentioned raw materials medicine according to the combination principle of monarch, should say that QI invigorating dehumidifying strength is much bigger.And picture Rhizoma Dioscoreae this class, on can lung moistening, in can spleen reinforcing, lower can reinforcing the kidney, look after more comprehensive.Obtained at insufficiency of the spleen, dyspepsia, vomiting, abdominal distention for the treatment of and the aspect such as become thin the curative effect of showing, made this medicine produce beyond thought effect aspect strengthening the spleen to promote digestion.And the present invention is pure Chinese medicinal preparation, through 1 year, observe both without recurring also without obvious toxic and side effects.
The specific embodiment
A kind of medicine of strengthening the spleen to promote digestion, by following bulk drugs, made:
Radix Astragali 30g, Rhizoma Dioscoreae 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Semen Coicis 30g, Rhizoma Coptidis 10g, Herba Taraxaci 30g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae Preparata 6g, Herba Dendrobii 20g, Cortex Eucommiae 15g, Radix Scutellariae 10g, Radix Dipsaci 15g, Poria 15g, Semen Oroxyli 10g, Cortex Magnoliae Officinalis 10g, Ramulus Cinnamomi 10g, Herba Agrimoniae 30g, Fructus Amomi 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Paeoniae Alba 15g, Fructus Aurantii 10g and Semen Lablab Album 10g;
Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.Every capsule has above-mentioned raw materials medicine 0.4g.
The drug effect of each crude drug of distinguishing the flavor of is as follows:
1. Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
2. Rhizoma Dioscoreae: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
3. Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.
4. Semen Coicis: spleen invigorating, eliminating dampness by diuresis, antidiarrheal, evacuation of pus.
5. Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
6. Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
7. Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
8. Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
9. Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.
10. the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
11. Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
12. Radix Dipsaci: invigorating the liver and kidney, bone and muscle strengthening, continuous folding wound, only metrorrhagia.
13. Poria: the Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.
14. Semen Oroxyli: lung moistening, soothing liver-QI, stomach function regulating, granulation promoting.
15. Cortex Magnoliae Officinalis: the dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.
16. Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.
17. Herba Agrimoniae: astringing to arrest bleeding, detoxification sore treatment, parasite killing, puckery antiperspirant, cough-relieving.
18. Fructus Amomi: the removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.
19. the Pseudobulbus Bletillae (Rhizoma Bletillae): tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.
20. the Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
21. Fructus Aurantii: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.
22. Semen Lablab Album: spleen reinforcing and in, removing dampness is relieved summer heat.
Instructions of taking: the people more than 18 years old three times on the one, each 1.Within 30 days, be a course for the treatment of, take continuously three courses for the treatment of.As taken continuously 1 week symptom without obviously changing or take medicine rear appearance diarrhoea and vomiting increase the weight of, drug withdrawal immediately, transference cure after drug withdrawal.
Clinical trial:
Choose 150 routine functional dyspepsias and with gastrointestinal upset as vomiting, abdominal distention and the Patients of Spleen Deficiency of becoming thin, in age 18-50 year, the course of disease is more than 3 months, in 2 months, do not carry out any treatment.Above-mentioned 150 routine patients are divided into to two groups for the treatment of group and matched groups, treatment group 100 examples, the capsule made with this enforcement is treated, and three times on the oral one, each 1 30 days is a course for the treatment of, takes continuously three courses for the treatment of.Matched group 50 examples, take the domperidone tablet treatment: oral, 10～20mg or suspension 10ml, every day 3～4 times, take 15～30 minutes ante cibum, within 15 days, is a course for the treatment of, takes continuously three courses for the treatment of.Then carry out clinical observation.
Period in a medicine treatment group self clinical observation on the therapeutic effect analysis result is as follows:
| The curative effect project | The treatment group number of cases | Improvement rate (%) |
| The vomiting number of times reduces | 90 | 90% |
| Abdominal distention is alleviated | 86 | 86% |
| Body weight increases | 88 | 88% |
| Appetite increases | 96 | 96% |
| Total improvement rate (%) | ? | 90% |
The clinical observation on the therapeutic effect analysis result of period in a medicine treatment group and matched group is as follows:
Efficacy assessment standard is as follows:
1, produce effects: vomiting is obviously controlled, and abdominal distention is obviously alleviated, and body weight increases, and appetite increases, the transference cure of all the other gastrointestinal upsets.
2, take a turn for the better: the vomiting number of times reduces or the intermittent time extends, and abdominal distention is alleviated to some extent, and body weight stops alleviating, and appetite makes moderate progress, and the symptom partial symptoms of all the other gastrointestinal upsets disappears.
3, invalid: symptom is without improving or increasing the weight of.
The comparison sheet of the clinical medicine side effect incidence rate of period in a medicine treatment group and matched group
Stomachache and Refuse to take medicine are clinical modal side effect as can be seen from the above table, but can progressively disappear after drug withdrawal.But tremble and the incidence rate of the side effect of having blood in stool, take the matched group of domperidone tablet apparently higher than the treatment group of taking capsule of the present invention, so the present invention does not have obvious toxic and side effects substantially.
Claims (2)
1. the medicine of a strengthening the spleen to promote digestion is characterized in that it is the medicament of being made by the crude drug of following parts by weight:
15 parts of 30 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 10 parts of Fructus Aurantiis and Semen Lablab Albums.
2. the medicine of strengthening the spleen to promote digestion according to claim 1, is characterized in that described medicament is capsule.
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| CN201310462743.6A CN103479955B (en) | 2013-09-30 | 2013-09-30 | A kind of medicine of strengthening the spleen to promote digestion |
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| CN201310462743.6A CN103479955B (en) | 2013-09-30 | 2013-09-30 | A kind of medicine of strengthening the spleen to promote digestion |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102772770A (en) * | 2012-08-03 | 2012-11-14 | 刘元田 | Traditional Chinese medicine composition for treating cold-damp affecting spleen syndrome |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772770A (en) * | 2012-08-03 | 2012-11-14 | 刘元田 | Traditional Chinese medicine composition for treating cold-damp affecting spleen syndrome |
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| Title |
|---|
| 李展等: "《基于数据挖掘探讨陈业强教授的脾胃学术思想》", 《中国中西医结合急救杂志》 * |
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