CN103479880B

CN103479880B - Chinese herbal composition for treating neurasthenia

Info

Publication number: CN103479880B
Application number: CN201310401035.1A
Authority: CN
Inventors: 王学松; 任秀华; 周彦彬
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-08-27
Filing date: 2013-08-27
Publication date: 2015-05-20
Anticipated expiration: 2033-08-27
Also published as: CN103479880A

Abstract

The invention discloses a Chinese herbal composition for treating neurasthenia. Neurasthenia belongs to the field of insomnia, amnesia and major depressive disorder of the traditional Chinese medicine and is mainly caused by heart-spleen deficiency; and patients which are mentally exhausted or students which study hard day and night suffer from qi and blood deficiency due to sadness and hematozemia, the mind cannot be nourished due to the qi and blood deficiency, and palpitation, insomnia and amnesia are caused by lack of mind nourishment. According to the invention, traditional Chinese medicines such as balanophora polyandra, obcordate leaf raspberry fruit, Chinese gall leaven, abrus cantoniensis hance, citrus chirocarpus, fragrant sarcococca fruit, cortex albiziae, radix paeoniae alba, root of procumbent indian mallow, sapodilla and liquorice, and the traditional Chinese medicines are decocted with water to form a decoction. Clinical trails prove that the total effective rate of the Chinese herbal composition reaches 96.2%, which is obviously better than that of a control group.

Description

One treats neurasthenic Chinese medicine composition

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to one and treat neurasthenic Chinese medicine composition.

Background technology

Neurasthenia is with easy excited and mental, the physical fatiguability of spirit for feature, and often with the neurosis disorder of emotion, mental symptoms.Its generation is relevant with long-term nervous and stress, and women's prevalence is apparently higher than male, and more than between twenty and fifty onset, clinical main manifestations is insomnia, dreaminess, forgetful, fatigue and weak, dizziness, tinnitus etc.Based on psychotherapy and Drug therapy in treatment, drug main will comprise anxiety, sedative hypnotic and tricyclics, and these medicines have obvious side effect and have the shortcomings such as drug dependence.

Summary of the invention

The object of this invention is to provide one and treat neurasthenic Chinese medicine composition.Primary disease belongs to that motherland's medical science " is insomnia ", " forgetful ", the category such as " strongly fragrant disease ", applicant clinically finding based on deficiency of both the heart and spleen.Patient Duo Yin works with one's mind excessively or day and night studies hard for student, and sad hematozemia, causes insufficiency of vital energy and blood, and insufficiency of blood is then difficult to nourish heart, lack of preservation of spirit then cardiopalmus, insomnia, forgetful.

The object of the invention is to be achieved through the following technical solutions, the neurasthenic Chinese medicine composition of this treatment is made up of the Chinese medicine of following weight portion: Herba Balanophorae polyandrae 10-15 part, Fructus Rubi obcordati 20-30 part, Mass Galla chinesis et camelliae Fermentata 9-18 part, Herba Abri 25-35 part, Fructus Citri Sarcodactylis 12-16 part, Fructus sarcococcae ruscifoliae 11-17 part, Cortex Albiziae 13-17 part, Radix Paeoniae Alba 15-18 part, Radix urenae procumbentis 14-19 part, Herba Herminii 20-22 part, Radix Glycyrrhizae 3-5 part.

Preferably, Herba Balanophorae polyandrae 13 parts, Fructus Rubi obcordati 25 parts, Mass Galla chinesis et camelliae Fermentata 14 parts, Herba Abri 30 parts, Fructus Citri Sarcodactylis 14 parts, Fructus sarcococcae ruscifoliae 15 parts, Cortex Albiziae 16 parts, the Radix Paeoniae Alba 18 parts, Radix urenae procumbentis 15 parts, Herba Herminii 21 parts, 4 parts, Radix Glycyrrhizae.

Above-mentioned Chinese medicine decocting is made decoction by preparation method.

Fang Zhong: Herba Balanophorae polyandrae, Fructus Rubi obcordati enriching yin and nourishing kidney, the kidney invigorating arresting seminal emission; Mass Galla chinesis et camelliae Fermentata, Fructus Citri Sarcodactylis, Herba Abri moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst, dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, heat-clearing and toxic substances removing; Fructus sarcococcae ruscifoliae, Cortex Albiziae, Radix Paeoniae Alba nourishing the liver are calmed the nerves, resolving depression, and promoting blood circulation and detumescence, nourishes blood, suppressing the hyperactive liver pain relieving; Radix urenae procumbentis, Herba Herminii invigorating the spleen to clear away damp pathogen, blood stasis dispelling is invigorated blood circulation, heart tonifying the kidney invigorating, stomach invigorating, regulating menstruation and activating blood; The invigorating middle warmer of Radix Glycyrrhizae QI invigorating, heat-clearing and toxic substances removing, alleviates pain relieving, the mediation property of medicine.

Clinical data

1, the routine patient of physical data 156 all comes from December, 2007 my institute's Neurology Department of in December ,-2009 and is in hospital and out-patient, all meet neurasthenic diagnostic criteria, great majority are that brain worker is as teacher, secretary, marketing personnel, accounting, researcher etc., without organic disease, often by insomnia, mental deficiency, anxious state of mind large etc. can not be autonomous symptom worries, do not take any remedy measures in the past.Be divided into two groups at random, treatment group 78 example, man 36 example, female 42 example; 21 ~ 60 years old age, average 41 years old; The course of disease is the shortest is 3 months, the longest 3 years.Matched group 78 example, man 32 example, female 44 example; 22 ~ 65 years old age, average 42 years old; The course of disease is the shortest is 4 months, the longest 4 years.The equal not statistically significants of difference (P>0.05) such as two groups of case sexes, age, occupation, the course of disease, state of an illness, have comparability.

2, criterion of therapeutical effect was with reference to People's Medical Officer Press's " clinical disease diagnosis is according to curing improvement standard " in 1998.Cure: the mental status and somatization disappear, and can recover the ability to work before disease and life; Take a turn for the better: the mental status and somatization disappear substantially, can be engaged in mental and physical exertion; Invalid: the mental status and somatization are not improved or increased the weight of.

3, observation index: adopt neurosis screening table average value as parameters for observation on effect.The Psycs's evaluation having 2 to work more than 5 years, respectively tests and assesses 1 time before the treatment with at the end of the course for the treatment of respectively, obtains each score overall average.Statistical method: adopt x2 to check t inspection.

4, Therapeutic Method treatment group patient takes Chinese medicine composition of the present invention, take Herba Balanophorae polyandrae 13g, Fructus Rubi obcordati 25g, Mass Galla chinesis et camelliae Fermentata 14g, Herba Abri 30g, Fructus Citri Sarcodactylis 14g, Fructus sarcococcae ruscifoliae 15g, Cortex Albiziae 16g, Radix Paeoniae Alba 18g, Radix urenae procumbentis 15g, Herba Herminii 21g, Radix Glycyrrhizae 4g, decocting becomes decoction, every day, potion, took at twice; The oral oryzanol of matched group patient, each 2, every day 3 times, two groups of homogeneous Zhou Weiyi courses for the treatment of.

5, after therapeutic outcome (1) two group treats two courses for the treatment of, comparitive study is in table 1.

Comparitive study after two courses for the treatment of of table 1 liang group treatment

Two groups are compared P<0.05

Two groups are compared, treatment group cure rate, and total effective rate, is obviously better than matched group, and two groups are compared and have comparability P<0.05.

Before and after (2) two groups of treatments, neurosis screening table appraisal result compares

Before and after two groups of treatments, neurosis handsome choosing table appraisal result compares

Note: compare with matched group, 1) t=0.2012, P>0.05,2) t ¹=14.2800

6, model case patient Wang, female, 45 years old, first visit in July, 2008.Because there is unsatisfactory thing in family, excessive thinking, usually has a sleepless night, and is difficult to people and sleeps, even lie awake all night, and headache, cardiopalmus, susceptible to lose temper due to restlessness, neurolysis, poor appetite, absentminded, hypomnesis, uses oryzanol, diazepam etc., poor effect.Carry out my institute's Neurology Department to go to a doctor, have a medical check-up without exception, red tongue, yellow fur, wiry and frequent pulse.Consult the every report in outer court, do not find that organic disease shows.Diagnosis: neurasthenia.Side Herba Balanophorae polyandrae 13g, Fructus Rubi obcordati 25g, Mass Galla chinesis et camelliae Fermentata 14g, Herba Abri 30g, Fructus Citri Sarcodactylis 14g, Fructus sarcococcae ruscifoliae 15g, Cortex Albiziae 16g, Radix Paeoniae Alba 18g, Radix urenae procumbentis 15g, Herba Herminii 21g, Radix Glycyrrhizae 4g; After medicine-feeding takes two courses for the treatment of, patients symptomatic takes a turn for the better, then after taking for 3 courses for the treatment of, thoroughly fully recovers, and follows up a case by regular visits to 3 months, does not recur again.

Detailed description of the invention

Embodiment one: take Herba Balanophorae polyandrae 13g, Fructus Rubi obcordati 25g, Mass Galla chinesis et camelliae Fermentata 14g, Herba Abri 30g, Fructus Citri Sarcodactylis 14g, Fructus sarcococcae ruscifoliae 15g, Cortex Albiziae 16g, Radix Paeoniae Alba 18g, Radix urenae procumbentis 15g, Herba Herminii 21g, Radix Glycyrrhizae 4g, makes decoction by above-mentioned Chinese medicine decocting.

Embodiment two: take Herba Balanophorae polyandrae 15g, Fructus Rubi obcordati 30g, Mass Galla chinesis et camelliae Fermentata 18g, Herba Abri 25g, Fructus Citri Sarcodactylis 12g, Fructus sarcococcae ruscifoliae 17g, Cortex Albiziae 13g, Radix Paeoniae Alba 15g, Radix urenae procumbentis 19g, Herba Herminii 20g, Radix Glycyrrhizae 5g, makes decoction by above-mentioned Chinese medicine decocting.

Embodiment three: take Herba Balanophorae polyandrae 10g, Fructus Rubi obcordati 20g, Mass Galla chinesis et camelliae Fermentata 9g, Herba Abri 35g, Fructus Citri Sarcodactylis 16g, Fructus sarcococcae ruscifoliae 11g, Cortex Albiziae 17g, Radix Paeoniae Alba 18g, Radix urenae procumbentis 14g, Herba Herminii 22g, Radix Glycyrrhizae 3g, makes decoction by above-mentioned Chinese medicine decocting.

Claims

1. the neurasthenic Chinese medicine composition for the treatment of, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight: Herba Balanophorae polyandrae 13g, Fructus Rubi obcordati 25g, Mass Galla chinesis et camelliae Fermentata 14g, Herba Abri 30g, Fructus Citri Sarcodactylis 14g, Fructus sarcococcae ruscifoliae 15g, Cortex Albiziae 16g, Radix Paeoniae Alba 18g, Radix urenae procumbentis 15g, Herba Herminii 21g, Radix Glycyrrhizae 4g, above-mentioned Chinese medicine decocting is made decoction.