CN103478718A - Functional food for improving concentration of glutathione in human body and preparation method of functional food - Google Patents
Functional food for improving concentration of glutathione in human body and preparation method of functional food Download PDFInfo
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- CN103478718A CN103478718A CN201310452145.0A CN201310452145A CN103478718A CN 103478718 A CN103478718 A CN 103478718A CN 201310452145 A CN201310452145 A CN 201310452145A CN 103478718 A CN103478718 A CN 103478718A
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- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 229940106589 milk thistle seed extract Drugs 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- LUKBXSAWLPMMSZ-UHFFFAOYSA-N resveratrol Chemical compound C1=CC(O)=CC=C1C=CC1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-UHFFFAOYSA-N 0.000 description 1
- 229960005055 sodium ascorbate Drugs 0.000 description 1
- 235000010378 sodium ascorbate Nutrition 0.000 description 1
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 description 1
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention belongs to the technical field of nutritional products, and particularly provides functional food for improving concentration of glutathione in a human body and a preparation method of the functional food. The functional food comprises a component A and a gain agent, wherein the component A consists of cystine, cystine-contained polypeptide and/or protein, glycine-contained polypeptide and/or protein as well as glutamic-acid-contained polypeptide and/or protein. With the adoption of the functional food for improving the concentration of glutathione in the human body and the preparation method of the functional food, glutathione synthesis in the human body can be promoted, and the concentration level of glutathione in the human body is improved, so that immune capacity of the human body is improved, and further, antioxidation and detoxication are achieved. The component A and the gain agent are matched for use, so as to more effectively improve the concentration of glutathione and the antioxidant effect. Protein and polypeptide are directly obtained from natural food, the taste is better, accordingly, the functional food is more suitable for being eaten by a human, and moreover, other essential amino acids for the human body are contained, so that the functional food is more beneficial to health of the human body; and glutathione is an important antioxidant in the human body, cellular oxidation is the cause of senility and various diseases, therefore, the functional food can be applied to prevention and adjuvant therapy of various diseases.
Description
Technical field
The present invention relates to the dietetic product technical field, relate in particular to a kind of functional food that improves human body glutathion inside concentration and preparation method thereof.
Background technology
Glutathione (Glutathione) is a ternary peptide, it is antioxidant in a kind of cell, it can catch free radical to avoid the destruction of radical pair cell tissue, thereby extremely important to the immune system of human body, is described as " in human body, best free radical is cleared away agent " by medical circle.But, human body can't directly obtain glutathione from food, even if directly Oral Administration of Glutathione can not improve the concentration of human body GSH-PX activity, because glutathione can not be absorbed by the human body gi system, thereby the concentration of raising human body glutathion inside must be synthetic in human body cell by certain material conditions.Glutathione reacts synthetic in two steps by glutamic acid, cysteine and glycine, and concrete route is as follows:
Accordingly, U.S. Pat RE42645E, Nutritional or therapeutic compositions and methods to increase bodily glutathione levels, disclose a kind of nutrition or medical composition that improves human body glutathion inside concentration, said composition mainly is comprised of glutamic acid (GlutamicAcid), Guang peace acid (Cystine) and glycine (Glycine).
The mode of directly taking the composition be comprised of three seed amino acids is different from the eating habit of people's daily life, and pure amino acid is not directly to take from nature food, and its mouthfeel, taste are unfavorable for that people generally accept.Use which material to replace that this three seed amino acid makes it form and mouthfeel people preferably are daily edible, the health that more is of value to human body becomes one of emphasis of the present invention.On the other hand, we can find out the synthetic route by glutathione, and in body, synthesizing glutathion not only needs essential amino acid, also needs suitable condition, as catalyst etc.Thereby the composition be comprised of which material can more effectively promote that in human body, synthesizing glutathion becomes second direction and focus of the present invention.
Amino acid is the component units of albumen, and a plurality of amino acid polymerizations form albumen or polypeptide (albumen of molecular weight), and as soybean protein is rich in glutamic acid, the collagen of animal base is rich in glycine, contains higher cystine in lactalbumin.After these albumen enter the stomach of human body, will resolve into each seed amino acid that forms them, be absorption of human body, become the nutriment that we sustain life.Adopt some specific protein that is rich in the peace acid of glutamic acid, Guang and glycine or polypeptide to replace single amino acid, as long as select properly, and, with the proportioning of science, these albumen or polypeptide can provide the human body glutathion inside to synthesize required amino acid.Simultaneously, these proteins and peptides directly come from nature food, more healthy, and mouthfeel is better, and human body preferably is edible, and the amino acid that contains other needed by human, more are of value to the health of human body.
Summary of the invention
The object of the present invention is to provide and a kind ofly improve human body glutathion inside concentration and mouthfeel is good, the edible functional food of suitable human body.
For achieving the above object, the present invention by the following technical solutions: a kind of functional food that improves human body glutathion inside concentration, described functional food is comprised of A component and B component,
Described A component consists of in any proportion following material: containing the polypeptide of glycine, containing the albumen of glycine, containing the polypeptide of glutamic acid, containing the albumen of glutamic acid, containing the polypeptide of cystine, containing the albumen of cystine, containing the polypeptide of cysteine, containing albumen and the cystine of cysteine;
Described B component is accelerant, and described accelerant is at least one in promoter and collaborative antioxidant;
Described promoter is at least one in vitamin C, vitamin D, vitamin B6, FA, cobalamin, calcitriol, acetylcysteine, S-adenosylmethionine, alpha lipoic acid and silymarin;
Described collaborative antioxidant is at least one in green-tea extract, grape seed extract, vitamin E, ginseng pulverate or ginseng extract, glossy ganoderma powder or Ganodenna Lucidum P.E, Chinese caterpillar fungus powder or Cordyceps extract, beta carotene, resveratrol and lycopene;
In described functional food, the mass percent of accelerant is 0-90%.
In optimal case, described cystine, the polypeptide that contains cystine or cysteine and/or albumen, the polypeptide that contains glycine and/or albumen, the polypeptide that contains glutamic acid and/or albumen are in mol ratio n(cystine in the A component): the n(glycine): the ratio of n(glutamic acid)=1:2:2 is mixed.
In other scheme, described cystine, containing the polypeptide of cystine or cysteine and/or albumen, containing the polypeptide of glycine and/or albumen, also can mix in any proportion containing polypeptide and/or the albumen of glutamic acid.
Described A component can be comprised of the arbitrary protein in table 1 and polypeptide.
Preferably, described A component consists of in any proportion following albumen or polypeptide: soybean protein and/or Soybean Peptide, collagen and/or gelatin, lactalbumin and cystine.
Preferably, described A component is comprised of albumen or the polypeptide of following weight quota: Soybean Peptide 60-180 part, collagen 20-80 part, lactalbumin 50-150 part and cystine 15-55 part.
Preferably, described A component is comprised of the material of following weight quota: 35 parts of 120 parts of Soybean Peptide, 50 parts of collagens, 100 parts of lactalbumins and cystines.
In described functional food, the mass percent of accelerant is 1-70%.
In described functional food, the mass percent of accelerant is 5-20%.
Described functional food is solid oral dosage form, and described solid oral dosage form is any in pulvis, granule, Tablet and Capsula.
Described functional food can be directly oral, and also available water or other beverage are as taking medicine after mixing with water such as fruit juice, milk, tea, coffees.
A kind of preparation method who improves the functional food of human body glutathion inside concentration: take respectively each material of composition function food by proportioning, then each material is mixed and obtain functional food.
The content of the common animal/vegetable protein Glutamic Acid of table 1, glycine and cystine
| ? | Glutamic acid (%) | Glycine (%) | Cystine (%) |
| Soybean protein (Soybean Peptide) | 20.47 | 4.57 | 1.45 |
| Collagen (ox-hide) | 6.86 | 33.53 | 0 |
| Collagen (pigskin) | 7.83 | 33.27 | 0 |
| Collagen (carp fish scale) | 7.1 | 34.03 | 0 |
| Collagen (Tilapia mossambica fish scale) | 7.08 | 32.85 | 0.05 |
| Albumen | 13.5 | 3.6 | 2.5 |
| Tuna albumen | 14.9 | 4.8 | 1.1 |
| Beef protein | 15.0 | 6.1 | 1.3 |
| Chicken protein | 15.0 | 4.9 | 1.3 |
| Lactalbumin | 16.8 | 2.2 | 2.2 |
| Casein | 21.5 | 2.1 | 0.3 |
By the data in table 1, can be found out, most of animal/vegetable protein all is rich in glutamic acid, and the content of glutamic acid is 20% left and right; Collagen is rich in glycine, and the content of glycine is greater than > 30%; In albumen, soybean protein and lactalbumin, the content of cystine is relatively high, but also only has 2% left and right.Therefore, but by combining different albumen and/or polypeptide and adding the A component in appropriate cystine composition function food; And, by adjusting the consumption of each component, can also make the mol ratio of key amino acid in the A component reach optimal proportion, i.e. the n(cystine): the n(glycine): n(glutamic acid)=1:2:2.
Also have in addition research to point out, the metabolin calcitriol (Calcitriol) of vitamin D, have the effect of catalysis glutathione synthesis, can increase the concentration of human brain GSH-PX activity.Acetylcysteine (N-acetyl cysteine), S-adenosylmethionine (S-adenosylmethionine), lactalbumin (Whey protein), alpha lipoic acid (Alpha lipoicacid), vitamin B6, FA, cobalamin and silymarin (silymarin, the Milk Thistle seed extract) also there is the cell of promotion synthesizing glutathion, the effect that improves body glutathion inside concentration.Thereby these compositions and A combination of components are formed to functional food, can more effectively promote the synthetic of human body cell glutathion inside.
Also have research to show, take the concentration that vitamin C can increase the red blood cell GSH-PX activity.Vitamin C itself is also a very strong antioxidant, extremely important to health.Inject glutathione and vitamin C is that the doctor is the complementary therapy that cancer patient is commonly used simultaneously, to increase immunity.Thereby vitamin C is also the synthetic auxiliary element of a good glutathione cell.
Further again, glutathione is antioxidant in a kind of cell.And natural health antioxidant commonly used also has the green-tea extract of vitamin E and plant base and grape seed extract etc.The main antioxidant component of green-tea extract comprises catechuic acid (catechin) and polyphenolic substance (Polyphenols).Wherein main catechuic acid has four: epicatechin (epicatechin), epigallocatechin (epigallocatechin), L-Epicatechin gallate (epicatechin gallate) and epigallocatechin gallate gallate (epigallocatechingallate) etc.The antioxidant effect of grape seed extract is mainly from polyphenolic substance (Polyphenols) and vitamin E etc., and one of them famous polyphenol is resveratrol (resveratrol).Although the antioxidative components of green-tea extract and grape seed extract is different from glutathione with mechanism, but itself and glutathione are share and have complementation, thereby more fully resist the aging caused by oxidation, reach the better effect of improving immunity, keeping fit.
Compared with prior art, the invention has the beneficial effects as follows: the present invention is by albumen and/or polypeptide containing cystine, glycine and glutamic acid, and cystine forms the A component, can promote synthesizing glutathion in human body, improve the concentration level of human body glutathion inside, thereby improve the human immunological competence, and there is antioxidation and detoxication.And A component and accelerant are used in conjunction with and can effectively strengthen the effect that functional food improves human body glutathion inside concentration.Because glutathione is very important antioxidant in human body, and cellular oxidation is the root of old and feeble and various diseases, so the present invention can be applicable to prevention and auxiliary curing various diseases.By albumen and/or polypeptide, for providing synthesizing glutathion necessary amino acid in body, these proteins and peptides directly come from nature, more healthy, and mouthfeel is better, and human body preferably is edible.In addition, except the amino acid containing also containing other needed by human the necessary amino acid of synthesizing glutathion, more be of value to the health of human body in these albumen or polypeptide.
The specific embodiment
In order to more fully understand technology contents of the present invention, below in conjunction with specific embodiment, technical scheme of the present invention is described further and illustrates.
Embodiment 1
Take respectively and be dry powder and be less than 20 purpose Soybean Peptide 12 grams, pigskin collagen 5 grams, lactalbumin 10 grams, cystine 3.5 grams and cane sugar powder 15 grams, be placed in cutting machine (Chopper-Grinder) mixing and within 2 minutes, obtain functional food.
The content of cystine, glutamic acid and glycine (in the various proteins and peptides that provide according to table 1, amino acid contained amount is calculated) as shown in table 2 in this functional food, the ratio of the amount of substance of cystine, glutamic acid and glycine approaches desired proportions 1:2:2 very much.
This functional food is applicable to men and women, old and young and takes, and gets these functional food 5 grams in cup, with taking after 100 milliliters of warm water impulsive motions, micro-sweet.Suggestion is taken 1-3 time every day, preferably continues to take with the normal higher glutathione concentrations of tool in holder.
Functional food Glutamic Acid, glycine and the Guang of table 2 embodiment 1 are pacified sour content
Embodiment 2
Take respectively and be dry powder and be less than 20 purpose Soybean Peptide 12 grams, pigskin collagen 5 grams, lactalbumin 10 grams, cystine 3.5 grams, sodium ascorbate 5 grams and cane sugar powder 15 grams, be placed in cutting machine (Chopper-Grinder) mixing and within 2 minutes, obtain functional food.
In this functional food, the content of cystine, glutamic acid and glycine is identical with data shown in table 2.
This functional food is applicable to men and women, old and young and takes, and gets these functional food 5 grams in cup, with taking after 100 milliliters of warm water impulsive motions, micro-sweet.Suggestion is taken 1-3 time every day, preferably continues to take with the normal higher glutathione concentrations of tool in holder.
Embodiment 3
Take respectively ganoderan extract 5 grams and cane sugar powder 15 grams that are dry powder and are less than 20 purpose Soybean Peptide 12 grams, Tilapia mossambica collagen 5 grams, lactalbumin 10 grams, cystine 3.5 grams, polyoses content >=30%, be placed in cutting machine (Chopper-Grinder) mixing and within 2 minutes, obtain functional food.
The content of cystine, glutamic acid and glycine (in the various proteins and peptides that provide according to table 1, amino acid contained amount is calculated) as shown in table 3 in this functional food, the ratio of the amount of substance of cystine, glutamic acid and glycine approaches desired proportions 1:2:2 very much.
This functional food is applicable to men and women, old and young and takes, and gets these functional food 5 grams in cup, with taking after 100 milliliters of warm water impulsive motions, micro-sweet.Suggestion is taken 1-3 time every day, preferably continues to take with the normal higher glutathione concentrations of tool in holder.
Functional food Glutamic Acid, glycine and the Guang of table 3 enforcement 1 are pacified sour content
Embodiment 4
Take respectively ganoderan extract 409.5 grams and cane sugar powder 150 grams that are dry powder and are less than 20 purpose Soybean Peptide 12 grams, Tilapia mossambica collagen 5 grams, lactalbumin 10 grams, cystine 3.5 grams, polyoses content >=30%, be placed in the three-dimensional mixer mixing and within 10 minutes, obtain functional food.
In this functional food, the content of cystine, glutamic acid and glycine is identical with data shown in table 3.
This functional food is applicable to men and women, old and young and takes, and gets these functional food 5 grams in cup, with taking after 100 milliliters of warm water impulsive motions, micro-sweet.Suggestion is taken 1-3 time every day, preferably continues to take with the normal higher glutathione concentrations of tool in holder.
The above only further illustrates technology contents of the present invention with embodiment, so that the reader is easier to understand, but does not represent that embodiments of the present invention only limit to this, and any technology of doing according to the present invention is extended or recreation, all is subject to protection of the present invention.
Claims (9)
1. a functional food that improves human body glutathion inside concentration, is characterized in that, described functional food is comprised of A component and B component,
Described A component consists of in any proportion following material: containing the polypeptide of glycine, containing the albumen of glycine, containing the polypeptide of glutamic acid, containing the albumen of glutamic acid, containing the polypeptide of cystine, containing the albumen of cystine, containing the polypeptide of cysteine, containing albumen and the cystine of cysteine;
Described B component is accelerant, and described accelerant is at least one in promoter and collaborative antioxidant;
Described promoter is at least one in vitamin C, vitamin D, vitamin B6, FA, cobalamin, calcitriol, acetylcysteine, S-adenosylmethionine, alpha lipoic acid and silymarin;
Described collaborative antioxidant is at least one in green-tea extract, grape seed extract, vitamin E, ginseng pulverate or ginseng extract, glossy ganoderma powder or Ganodenna Lucidum P.E, Chinese caterpillar fungus powder or Cordyceps extract, beta carotene, resveratrol and lycopene;
In described functional food, the mass percent of accelerant is 0-90%.
2. improve according to claim 1 the functional food of human body glutathion inside concentration, it is characterized in that, described cystine, containing the polypeptide of cystine or cysteine and/or albumen, containing the polypeptide of glycine and/or albumen, containing the polypeptide of glutamic acid and/or albumen by mol ratio n cystine in the A component: n glycine: the ratio mixing of n glutamic acid=1:2:2.
3. improve according to claim 1 the functional food of human body glutathion inside concentration, it is characterized in that, described A component consists of in any proportion following material: soybean protein and/or Soybean Peptide, collagen and/or gelatin, lactalbumin and cystine.
4. improve according to claim 3 the functional food of human body glutathion inside concentration, it is characterized in that, described A component is comprised of the material of following weight quota: Soybean Peptide 60-180 part, collagen 20-80 part, lactalbumin 50-150 part and cystine 15-55 part.
5. improve according to claim 4 the functional food of human body glutathion inside concentration, it is characterized in that, described A component is comprised of the material of following weight quota: 35 parts of 120 parts of Soybean Peptide, 50 parts of collagens, 100 parts of lactalbumins and cystines.
6. according to the functional food of the described raising human body of claim 1-5 any one glutathion inside concentration, it is characterized in that, in described functional food, the mass percent of accelerant is 1-70%.
7. improve according to claim 6 the functional food of human body glutathion inside concentration, it is characterized in that, in described functional food, the mass percent of accelerant is 5-20%.
8. according to the functional food of the described raising human body of claim 1-5 any one glutathion inside concentration, it is characterized in that, described functional food is solid oral dosage form, and described solid oral dosage form is any in pulvis, granule, Tablet and Capsula.
9. a preparation method who improves as claimed in claim 1 the functional food of human body glutathion inside concentration, is characterized in that, takes respectively each material of composition function food by proportioning, then each material mixed and obtain functional food.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104585763A (en) * | 2015-01-28 | 2015-05-06 | 广西博科药业有限公司 | Liver-protecting and liver-nourishing functional food and preparation method thereof |
| CN105831769A (en) * | 2015-02-04 | 2016-08-10 | 张亚武 | Intracellular/intercellular cancer inhibiting food |
| CN111132679A (en) * | 2017-07-10 | 2020-05-08 | 努瑞比尔公司 | Food supplement for protecting fertility in women and men |
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| CN111132679A (en) * | 2017-07-10 | 2020-05-08 | 努瑞比尔公司 | Food supplement for protecting fertility in women and men |
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| CN103478718B (en) | 2015-10-28 |
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