CN103478549B - Whole-grain full-nutrition formula food for epileptic consumption - Google Patents
Whole-grain full-nutrition formula food for epileptic consumption Download PDFInfo
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- CN103478549B CN103478549B CN201310384020.9A CN201310384020A CN103478549B CN 103478549 B CN103478549 B CN 103478549B CN 201310384020 A CN201310384020 A CN 201310384020A CN 103478549 B CN103478549 B CN 103478549B
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/14—Yeasts or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pediatric Medicine (AREA)
- Microbiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a whole-grain full-nutrition formula food for epileptic consumption, and relates to the technical field of health foods. The whole-grain full-nutrition formula food is processed by black soya bean, soybean, groundnut kernels, corn starch, wheat bran, whey protein, herbal powder, glutamic acid, se-enriched yeast, stevioside and edible essence in a mixing manner. By adopting the food, various nutrient elements and Chinese herbal medicinal ingredients are reasonably assorted aiming at special requirements of epileptic on nutrition and microelements, so as to cooperatively act. The whole-grain full-nutrition formula food has excellent auxiliary treatment effect and nutrient health-care effect on the epileptic, particularly the epileptic resistant to healing. The food is good in taste, abundant in nutrition, free of toxic and side effects, and suitable for long-term consumption of the epileptic.
Description
Technical field
The present invention relates to health food technology field, be specifically related to a kind of full nutrient formulation food eating for epileptic.
Background technology
Epilepsy is the of short duration brain function imbalance of chronic repeated relapsing syndrome.Cause repeatedly that taking brain neuron paradoxical discharge epilepsy outbreak is as feature.Epilepsy is one of nervous system common disease, and illness rate is only second to cerebral apoplexy.Epileptics is a kind of common brain section disease, except outside the Pass having with inherent cause, the outbreak of epileptics also with bad day after tomorrow condition element relevant, as brain trauma, infection, poisoning, ICT etc.
The treatment of epilepsy can be divided into controls outbreak, etiological treatment, surgical intervention, general health and five aspects of prevention.Wherein the most important thing is to control outbreak, at present taking medicine treatment as main.
Epileptic is also noted that Control drink and food simultaneously, overcomes custom, the especially Patients with Epilepsy in Childhoods such as partial eclipse, different food, crapulence, gluttony, and hyperalimentation tends to bring out epileptic attack.That epileptic will eat more is being rich in nutrition, be easy to the food of digestion, as wheaten food, beans (black soya bean, pea, soya bean), lean meat, egg, fish, milk etc., especially should many Food Legumes, fresh vegetables, fruit, dairy products, the food that these are rich in high protein and phosphatide, contributes to the recovery of brain function and reduces attack times.
What the traditional Chinese medical science was thought epilepsy is is trouble by wind, fire, phlegm, the stasis of blood, cause the heart, liver,spleen,kidney, visceral-qi imbalance, positive high, positive high liver wind agitation, high and hot Sheng, heat Shengization fire, fire are extremely made wind, the help of wind fire is to suffer from for the deficiency of liver-yin and kidney-yin, the deficiency of Yin, decline knot in sputum, in blinded judgment, the unsuccessful stasis of blood of painstaking effort, the stasis of blood of another insufficiency of the spleen mistake fortune, clear QI failing to ascend, foul smell disturbed key clearly on blockage of main and collateral channels, phlegm resistance blood stasis, causes eventually epileptic attack.According to pathogenesis, normal adopt determine that epilepsy relieves dizziness, high fever, infantile convulsions, epilepsy, etc., flat liver purging intense heat, eliminate the phlegm have one's ideas straightened out, promoting blood circulation and removing blood stasis be methods for the treatment of.
The present invention controls the advantage of chronic disease, difficult treatment just in conjunction with dietetic regulation and Chinese medicine, grope, scientific research by repeatedly practising, and obtains one group of composition of raw materials, this formula to epilepsy, particularly control for a long time unchangeable epilepsy and have good adjuvant treatment effect.
Summary of the invention
The technical problem to be solved in the present invention is, manufactures a kind of health food, and this food is full nutrient formulation, can meet the specific demand of epileptic to nutrition, epilepsy is had to the effect of good supplemental treatment, can eat for a long time, has no side effect.
In order to overcome the above problems, the invention provides a kind of food, this food is taking black soya bean, soya bean, peanut, cornstarch as basic material, adds wheat bran forced for vitamins B6; Add lactalbumin, glutamic acid strengthening high-quality protein and useful amino acid; Add Se-enriched yeast reinforced micro-element selenium; Add the traditional Chinese medicine powder that the meticulous Chinese medicine proved recipe of allocating is made.Each raw material of this food is as follows by weight: black soya bean 14-18 part, soya bean 10-14 part, shelled peanut 8-12 part, cornstarch 7-9 part, wheat bran 7-9 part, lactalbumin 5-7 part, traditional Chinese medicine powder 1.0-1.4 part, glutamic acid 0.3-0.5 part, Se-enriched yeast 0.035-0.045 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.011-0.015 part.Wherein best proportioning is: 16 parts, black soya bean, 12 parts of soya beans, 10 parts, shelled peanut, 8 parts of cornstarch, 8 parts of wheat brans, 6 parts of lactalbumins, 1.2 parts of traditional Chinese medicine powder, 0.4 part, glutamic acid, 0.04 part of Se-enriched yeast, 0.2 part of steviol glycoside, 0.013 part of flavoring essence.
The Chinese prescription of the traditional Chinese medicine powder of adding in this food is as follows by weight: REALGAR 16-20 part, radix bupleuri 7-11 part, Radix Angelicae Sinensis 10-14 part, root of large-flowered skullcap 12-16 part, yncaria stem with hooks 16-20 part, arisaema cum bile 11-15 part, agalloch eaglewood 13-17 part, fructus alpiniae oxyphyllae 13-17 part, rhizoma Gastrodiae 14-18 part, tuber of pinellia 7-11 part, Radix Codonopsis 8-12 part, root tuber of aromatic turmeric 10-14 part, Radix Glycyrrhizae 8-12 part, levisticum 11-15 part, ginger 8-12 part.Wherein optimal proportion is: 18 parts of REALGARs, 9 parts of radix bupleuri, 12 parts of Radix Angelicae Sinensis, 14 parts of the roots of large-flowered skullcap, 18 parts of yncaria stems with hooks, 13 parts of arisaema cum bile, 15 parts of agalloch eaglewood, 15 parts of fructus alpiniae oxyphyllaes, 16 parts, rhizoma Gastrodiae, 9 parts of the tuber of pinellia, 10 parts of Radix Codonopsis, 12 parts of root tubers of aromatic turmeric, 10 parts, Radix Glycyrrhizae, 13 parts of levisticums, 10 parts, ginger.
The processing technology of this food is:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR, radix bupleuri, Radix Angelicae Sinensis, the root of large-flowered skullcap, yncaria stem with hooks, arisaema cum bile, agalloch eaglewood, fructus alpiniae oxyphyllae, rhizoma Gastrodiae, the tuber of pinellia, Radix Codonopsis, root tuber of aromatic turmeric, Radix Glycyrrhizae, levisticum, ginger, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean, soya bean, shelled peanut, cornstarch, wheat bran, lactalbumin, traditional Chinese medicine powder, glutamic acid, Se-enriched yeast, steviol glycoside, flavoring essence, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) gained scattered paste shape thing makes finished product.
Food of the present invention can be made powdery, graininess or block food.
Of the present invention a kind of for the edible full nutrient formulation food of five cereals of epileptic, its primary raw material has following several:
Black soya bean: smooth or have wrinkle, tool gloss, a side to have yellowish white oblong hilum.Matter is hard.Gas is micro-, lightly seasoned, and that chews has a beans fishy taste.Black soya bean, has another name called big shield beans, material beans, zero black beans, and teata glycinis and the equine beans of claiming among the people, to the laudatory title that has the king in beans more.
In black soya bean, be rich in multiple nutritional components, the shortage of the various nutrients to human body has good supplementary function, and the needs of patients of some disease is had some the food of bean product more.From nutrition aspect, much research in recent years, except with its isoflavones, also have with its lecithin content abundant especially also with relation.These two have anti arteriosclerosis equally, this effect of norcholesterol.The mineral matter such as calcium, magnesium in black soya bean can also be alleviated the anxiety of internal organ (except heart) smooth muscle, plays hemangiectasis, promotes the effect of blood circulation, thereby hypertension is played to mitigation, can say that black soya bean is the bean product that hyperpietic can eat more.
Soya bean: containing rich in protein, wherein containing the several amino acids of needed by human, especially the highest with lysine content; Containing significant quantities of fat, be wherein mainly unrighted acid (linoleic acid, oleic acid, leukotrienes etc.); And phosphorus ester, calcium, phosphorus, iron, potassium, sodium, carrotene, Cobastab
1, B
2, B
12, the compositions such as nicotinic acid, folic acid, choline, daidzin, saponin.
Soybean is rich in isoflavones, can break off cancer cell nutrition supply, and containing 8 seed amino acids of needed by human, multivitamin and various trace elements, can reduce blood cholesterol, preventing hypertension, coronary heart disease, moving fat sclerosis etc.Soya bean includes linoleic acid, can promote children's neurodevelopment.The traditional Chinese medical science is thought, soya bean, and taste is sweet, and property is flat.Energy invigorating spleen to remove dampness, beneficial blood qi-restoratives, removing toxic substances.
Shelled peanut: the protein content of peanut is 25%--30%, eight seed amino acids that peanut protein contains needed by human, arginine content is higher than other nut, and biological value is higher than soybean.Eat a certain amount of peanut, peanut oil or (Groundnut products) every day, a large amount of albumen, fat and energy can not only be provided and can reduce meals saturated fat and the absorption of increase unrighted acid, greatly promote these absorptions to healthy and helpful nutrient such as phytoprotein, dietary fiber, vitamin E, folic acid, potassium, magnesium, zinc, calcium.
Peanut itself is the plant food of high energy, high protein and high lipid, not containing cholesterol and trans-fatty acid, and be rich in micronutrient, the materials such as phytosterol, resveratrol, isoflavones, antioxidant, there is important health-care effect, the outstanding substitute of breast, carnivorous thing, has important function to balanced diet, the nutrition that improves Chinese residents and health status especially.
Eat (Groundnut products) more, be conducive to reduce blood fat, increase HDL level.Physician's investigation is found: eat peanut and be negative correlativing relation with the real myocardial inyaretion of sending out.Penny professor's research shows, eats weekly twice peanut or its goods, and the real probability of sending out deaths from heart disease reduces 40%.
Cornstarch: claim again corn starch, popular name maize powder.The micro-yellowish powder of white.In cornstarch, be mainly carbohydrate, also contain a small amount of fat, protein and trace element etc.Corn is universally acknowledged " gold crop ", its fat, P elements, Cobastab
2content occupy first of cereal.In corn flour, contain linoleic acid and vitamin E, can make cholesterol in human body level reduce, thereby reduce arteriosclerotic generation.Calcic in corn flour, irony are more, can prevent hypertension, coronary heart disease.Modern medicine study shows in corn flour, there is abundant glutathione, and this is a kind of anticancer factor, in human body, can combine with multiple external chemical carcinogen, makes it lose toxicity, then excretes by alimentary canal.In the corn flour of corase grind, contain a large amount of lysine, can suppress tumor growth.Corn flour also contains trace elements of selenium, and selenium can accelerate human body inner oxide and decompose, and suppresses malignant tumour.Abundant dietary fiber in corn flour, can promote enterocinesia, shortens food by the gastral time, reduces absorption and the stimulation of carcinogen to colon of noxious material, thereby can reduce the generation of colon cancer.
Wheat bran: be the seed coat of wheat, the product after wheat decortication.The nutritive value of wheat bran is very high, and its main component is cellulose, contains in addition the nutritional labelings such as iron, potassium, vitamin (being mainly b family).Wherein Cobastab
6beneficial to epileptic patient.In addition, some research shows: often eat the coarse food grains such as wheat bran and can reduce cholesterol, prevent colon cancer, breast cancer, atherosclerotic etc.Dietary fiber content in rice bran and wheat bran is the highest, and the wriggling that they can promote large intestine, shortens the time that food stops in large intestine, anti-treating constipation; They can be as sponge on the other hand, the noxious material in absorption enteron aisle, and excrete in time, reduce the absorption of enteron aisle to useless poisonous substance matter.
Lactalbumin: be a kind of protein being present in nearly all mammal milk, formed by 123 amino acid residues, its amino acid sequence and stereochemical structure all with lysozyme homology, be a subunit of lactose synthase.Lactalbumin is called as the king of albumen, is a kind of protein extracting from milk, have to be of high nutritive value, absorption easy to digest, to contain the features such as various active composition, and be one of generally acknowledged human body good protein replenishers.
Traditional Chinese medicine powder: the Chinese prescription of the traditional Chinese medicine powder in food formula of the present invention is on the basis of traditional recipe, meticulously allocates and forms through clinical testing, and this prescription Chinese medicine used is respectively:
REALGAR: taste is pungent, bitter, property flat.The thoughts of returning home, liver, spleen, stomach, large intestine channel.Anticancer, relieving convulsion, the desinsection of eliminating the phlegm of relieving internal heat is treated sore, anti-inflammatory detumescence.
Radix bupleuri: cold nature, bitter, pungent.Return Liver Channel, gallbladder channel.Tool soothing liver-gallbladder, strongly fragrant, the loose effect of fire of thin gas solution.Table expels the heat-evil thoroughly, soothing liver-qi stagnation, elevate a turnable ladder yang-energy.Cure mainly cold, fever, fever and chills deficient fever.Children's's acne rash waste heat, lean and haggard belly expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus comes off, irregular menstruation.
Radix Angelicae Sinensis: taste is sweet; Pungent; Bitter; Warm in nature.Return liver; The heart; The spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Cure mainly all cards of the deficiency of blood; Irregular menstruation; Through closing; Dysmenorrhoea; Abdominal mass knot is poly-; Uterine bleeding; Asthenia cold abdominalgia; Impotence numbness; Numbness; Intestines are dry just difficult; Heavy after dysentery characterized by blood in the stool; Ulcer sores; Injury from falling down.
The root of large-flowered skullcap: bitter, cold in nature.Return lung, courage, spleen, stomach, large intestine, small intestinl channel.Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive, hypotensive.For damp-warm syndrome, the heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, rushes down dysentery, jaundice, and cough with lung heat, high hot polydipsia, blood-head is told nosebleed, carbuncle sore tumefacting virus, fetal irritability
Yncaria stem with hooks: sweet-bitter flavor; Cold nature.Return Liver Channel, the heart channel of Hang-Shaoyin.The flat liver of heat-clearing; Relieving convulsion and spasm.Cure mainly child convulsion; The morbid night crying of babies; Heat is contained moving wind; Eclampsia; Dizziness due to hyperactivity of liver-YANG; Irascibility distending pain in the head.
Arisaema cum bile: bitter is cold, micro-pungent, cool in nature.Return lung, liver, the spleen channel.Clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, apoplexy phlegm fan, demented frightened epilepsy.
Agalloch eaglewood: taste is pungent, bitter, warm in nature.Return spleen, stomach, kidney, lung channel.In sending down abnormally ascending temperature, warm kidney is supporing yang.Cure mainly the circulation of vital energy in the wrong direction and pant, vomiting hiccup, abdominal distention, waist knee void is cold, and large intestine void is secret, and urine gas drenches, man's cold sperm.
Fructus alpiniae oxyphyllae: taste is pungent; Warm in nature.Enter the heart, spleen; Kidney channel.Temperature kidney controlling nocturnal emission with astringent drugs contracting urine, phlegm is taken the photograph in warm spleen appetizing.Cure mainly deficiency-cold in spleen and stomach; Vomiting; Have loose bowels; Cold educating in abdomen; The many salivas of mouth; Enuresis with renal asthenia; Frequent micturition; Seminal emission; Gonorrhoea, the diseases such as many salivas.
Rhizoma Gastrodiae: taste is sweet, property is flat, returns Liver Channel.Breath wind stops convulsion, calming the liver, dispelling wind and removing obstruction in the meridians.Containing vanillyl alcohol, vanillin, gastrodin, polysaccharide, retinoid material, mucilaginous substance.
The tuber of pinellia: taste is pungent, warm in nature, poisonous; Return spleen, stomach, lung channel.Function is eliminating dampness and eliminating phlegm, and middle stomach invigorating, stopping nausea and vomiting by lowering the adverse flow of QI, and dissolving lump and resolving mass, external application can swelling and pain relieving.
Radix Codonopsis: property is flat, sweet, the micro-acid of taste.Return spleen, lung channel.Tonifying middle-Jiao and Qi, invigorating the spleen benefit lung.For a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst.
Root tuber of aromatic turmeric: taste is pungent, bitter, cold in nature.Return liver, the heart, lung channel, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice, promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire.
Radix Glycyrrhizae: taste is sweet, property is flat, nontoxic.Cure mainly vital organs of the human body fever and chills perverse trend, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw purging intense heat heat, the ripe use exterior cold of fall apart of use, goes pharyngalgia, removes heat symptoms caused by an exopathgen, delays healthy tendency, yin-nourishing blood, tonifying spleen and stomach, moistening lung.
Levisticum: taste is pungent, bitter, slightly warm in nature.Return liver, kidney, urinary bladder channel.Cure mainly expelling wind and eliminating dampness; Eliminating cold to stop pain.For wind-cold-dampness arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache dentalgia.
Ginger: taste is pungent, hot in nature.Return spleen, stomach, the heart, lung channel.Warming spleen and stomach for dispelling cold, Hui Yang promotes blood circulation, eliminating dampness dissolving phlegm, warming lung to reduce watery phlegm.Cure mainly coldness and pain in the epigastrium; Vomiting; Have loose bowels, yang depletion is fainted contrary; Cold drink is breathed with cough; Numbness and ache of cold dampness.
Glutamic acid: be a kind of acidic amino acid.Molecule includes two carboxyls, and chemical name is alpha-amido glutaric acid.Glutamic acid is one of amino acid forming in protein, although it is not the necessary amino acid of human body, it can be used as carbon nitrogen nutrition and organism metabolism, has higher nutritive value.After glutamic acid is absorbed by the body, easy and blood ammonia forms paddy acyl ammonia, can remove the toxic action of ammonia in metabolic process, thereby can prevent and treat hepatic coma, and protection liver, is the ancillary drug of patients with liver diseases.Brain tissue can only be oxidized glutamic acid, and can not be oxidized other amino acid, therefore glutamine can be used as the energy matter of brain tissue, improves and maintains cerebral function.Glutamic acid is as nerve center and corticocerebral tonic, for treating cerebral concussion or neurotrosis, epilepsy and mentally retarded child all being had to certain curative effect.
Se-enriched yeast: Se-enriched yeast is exactly to add selenium element in the process of culture yeasts, when yeast growth, absorb selenium, the protein of selenium in yeast body and polysaccharide organic are combined and are converted into Biological Selenium, stimulate thereby eliminated the toxicity of chemical selenium (as sodium selenite) to human body and stomach, make the selenium utilization that can more efficiently, more safely be absorbed by the body.Se-enriched yeast be also up to now domestic the most efficiently, the selenium-replenishing preparation that the safest, nutrition is the most balanced.
The edible Se-enriched yeast of the present invention is containing finished product Se-enriched yeast powder more than selenium 2000mg/kg, and adding Se-enriched yeast is for reinforced micro-element selenium, because selenium element is the vectorial mineral nutrient of needed by human, in human body, cannot synthesize.Selenium is very important to brain function, selenium deficiency changes the metabolic rate of " neurotransmitter ", in body, produce a large amount of harmful substance free radicals also cannot be removed simultaneously in time, thereby affect the brain function of human body, not only can reduce and increase selenium the generation that children are difficult to the epilepsy of curing, also anxiety reduction, depression and tired effectively, this effect is the most obvious in scarce selenium crowd.
Steviol glycoside: be a kind of sucrose succedaneum, can not increase in the situation of heat, increase the sweet taste of food.
Compared with prior art, disclosed by the invention a kind of for the edible full nutrient formulation food of five cereals of epileptic, there is following characteristics and significantly technological progress:
1, food of the present invention has met the specific demand of epileptic to diet, when a large amount of high-quality proteins and lecithin are provided, vitamin, trace element and amino acid that patient is badly in need of are strengthened, in the formula range through repetition test gained, these nutriments can act synergistically, and reach the effect of good nutrition and supplemental treatment.
2, food of the present invention has also added through the clinical practice Chinese prescription of allotment meticulously, in supplementing the nutrients, patient is played to the effect of supplemental treatment and conditioning; And in raw-food material ratio range of the present invention, traditional Chinese medicine ingredients and various nutrient synergy, reached beat all technological achievement with small addition, specifically sees embodiment 9.
3, food of the present invention is to epileptic, and particularly controlling for a long time the epileptic that difficulty heals has good adjuvant treatment effect and nutrition health-care functions, and this food mouthfeel is good, nutritious, have no side effect, and applicable epileptic is edible for a long time.
Detailed description of the invention
Be below the specific embodiment of the present invention, described embodiment is in order to further describe the present invention, instead of restriction the present invention.
The preparation of embodiment 1 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 160g, radix bupleuri 70g, Radix Angelicae Sinensis 100g, root of large-flowered skullcap 120g, yncaria stem with hooks 160g, arisaema cum bile 110g, agalloch eaglewood 130g, fructus alpiniae oxyphyllae 130g, rhizoma Gastrodiae 140g, tuber of pinellia 70g, Radix Codonopsis 80g, root tuber of aromatic turmeric 100g, Radix Glycyrrhizae 80g, levisticum 110g, ginger 80g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 14kg, soya bean 10kg, shelled peanut 8kg, cornstarch 7kg, wheat bran 7kg, lactalbumin 5kg, traditional Chinese medicine powder 1.0kg, glutamic acid 0.3kg, Se-enriched yeast 0.035kg, steviol glycoside 0.1kg, flavoring essence 0.011kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 2 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 200g, radix bupleuri 110g, Radix Angelicae Sinensis 140g, root of large-flowered skullcap 160g, yncaria stem with hooks 200g, arisaema cum bile 150g, agalloch eaglewood 170g, fructus alpiniae oxyphyllae 170g, rhizoma Gastrodiae 180g, tuber of pinellia 110g, Radix Codonopsis 120g, root tuber of aromatic turmeric 140g, Radix Glycyrrhizae 120g, levisticum 150g, ginger 120g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 18kg, soya bean 14kg, shelled peanut 12kg, cornstarch 9kg, wheat bran 9kg, lactalbumin 7kg, traditional Chinese medicine powder 1.4kg, glutamic acid 0.5kg, Se-enriched yeast 0.045kg, steviol glycoside 0.3kg, flavoring essence 0.015kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 3 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 170g, radix bupleuri 80g, Radix Angelicae Sinensis 110g, root of large-flowered skullcap 130g, yncaria stem with hooks 170g, arisaema cum bile 120g, agalloch eaglewood 140g, fructus alpiniae oxyphyllae 140g, rhizoma Gastrodiae 150g, tuber of pinellia 80g, Radix Codonopsis 90g, root tuber of aromatic turmeric 110g, Radix Glycyrrhizae 90g, levisticum 120g, ginger 90g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 15kg, soya bean 11kg, shelled peanut 9kg, cornstarch 8kg, wheat bran 8kg, lactalbumin 6kg, traditional Chinese medicine powder 1.1kg, glutamic acid 0.4kg, Se-enriched yeast 0.038kg, steviol glycoside 0.15kg, flavoring essence 0.012kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 4 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 190g, radix bupleuri 100g, Radix Angelicae Sinensis 130g, root of large-flowered skullcap 150g, yncaria stem with hooks 190g, arisaema cum bile 140g, agalloch eaglewood 160g, fructus alpiniae oxyphyllae 160g, rhizoma Gastrodiae 170g, tuber of pinellia 100g, Radix Codonopsis 110g, root tuber of aromatic turmeric 130g, Radix Glycyrrhizae 110g, levisticum 140g, ginger 110g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 17kg, soya bean 13kg, shelled peanut 11kg, cornstarch 8kg, wheat bran 8kg, lactalbumin 6kg, traditional Chinese medicine powder 1.3kg, glutamic acid 0.4kg, Se-enriched yeast 0.042kg, steviol glycoside 0.25kg, flavoring essence 0.014kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 5 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 160g, radix bupleuri 110g, Radix Angelicae Sinensis 100g, root of large-flowered skullcap 160g, yncaria stem with hooks 160g, arisaema cum bile 150g, agalloch eaglewood 130g, fructus alpiniae oxyphyllae 170g, rhizoma Gastrodiae 140g, tuber of pinellia 110g, Radix Codonopsis 80g, root tuber of aromatic turmeric 140g, Radix Glycyrrhizae 80g, levisticum 150g, ginger 80g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 18kg, soya bean 10kg, shelled peanut 12kg, cornstarch 7kg, wheat bran 9kg, lactalbumin 5kg, traditional Chinese medicine powder 1.4kg, glutamic acid 0.3kg, Se-enriched yeast 0.045kg, steviol glycoside 0.1kg, flavoring essence 0.015kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 6 nutrient powder of the present invention:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR 180g, radix bupleuri 90g, Radix Angelicae Sinensis 120g, root of large-flowered skullcap 140g, yncaria stem with hooks 180g, arisaema cum bile 130g, agalloch eaglewood 150g, fructus alpiniae oxyphyllae 150g, rhizoma Gastrodiae 160g, tuber of pinellia 90g, Radix Codonopsis 100g, root tuber of aromatic turmeric 120g, Radix Glycyrrhizae 100g, levisticum 130g, ginger 100g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean 16kg, soya bean 12kg, shelled peanut 10kg, cornstarch 8kg, wheat bran 8kg, lactalbumin 6kg, traditional Chinese medicine powder 1.2kg, glutamic acid 0.4kg, Se-enriched yeast 0.04kg, steviol glycoside 0.2kg, flavoring essence 0.013kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The traditional Chinese medicine powder preparation (by optimization formula) that embodiment 7 the present invention add:
Accurately take each taste Chinese medicine by described formula above: REALGAR 180g, radix bupleuri 90g, Radix Angelicae Sinensis 120g, root of large-flowered skullcap 140g, yncaria stem with hooks 180g, arisaema cum bile 130g, agalloch eaglewood 150g, fructus alpiniae oxyphyllae 150g, rhizoma Gastrodiae 160g, tuber of pinellia 90g, Radix Codonopsis 100g, root tuber of aromatic turmeric 120g, Radix Glycyrrhizae 100g, levisticum 130g, ginger 100g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder.
Embodiment 8 the present invention do not add the nutrient powder preparation (by optimization formula) of traditional Chinese medicine powder:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take various raw meal by described formula above: black soya bean 16kg, soya bean 12kg, shelled peanut 10kg, cornstarch 8kg, wheat bran 8kg, lactalbumin 6kg, glutamic acid 0.4kg, Se-enriched yeast 0.04kg, steviol glycoside 0.2kg, flavoring essence 0.013kg, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
3) by 2) oven dry of gained scattered paste shape thing, pulverize, cross 80 sieves, 50g/ bag packaging, is finished product.
The clinical testing of embodiment 9 nutrient powder of the present invention:
Clinical testing is divided into two parts, and Part I is acute and chronic toxicity test, and Part II is lanqin oral solutions.
(1) animal acute toxicity and chronic toxicity experiment:
Preliminary experiment shows, nutrient powder of the present invention, and toxicity is very little, cannot measure LD
50, therefore, according to maximum amount feeding.
1, animal acute toxicity test
Medicine: the embodiment of the present invention 6 and embodiment 8 gained nutrient powder.
Experimental animal: regular grade NIH mouse, body weight 20g ± 2g, male and female half and half.
Method and result:
1) by two kinds of each 50g of nutrient powder, be modulated into pasty state by 150ml warm water respectively.
2) experiment mice is divided at random to two groups of male and female half and half, two kinds of nutrient powder of feeding are stuck with paste respectively, volume 2ml/10g body weight, and close observation 8h also notes down, and continues to observe 7 days;
3) in 7 days, mouse is without death, and behavior is active, and food ration is as usual, and hair color light, without loose dirty, is had a liking for saliva without fainting from fear, and eye, mouth, nose, ear and crissum are without abnormal secretion, without the rotten toe of docking.From two groups, select respectively 10 execution, finding of naked eye: in the heart, liver, lung, stomach and the important organ such as thymus gland, no abnormality seen changes, and shows that two kinds of these nutrient powder are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 6 and embodiment 8 gained nutrient powder.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
1) configuration of two kinds of nutrient powder: be divided into high, medium and low three dosage groups, be respectively 240,120,60 times of edible for patients amount, be mixed into pasty state with warm water 1:1 respectively;
2) experimental mouse is divided into two groups at random, the nutrition that feeding modulates continuously is respectively stuck with paste, feeding 180 days continuously, observe animal general toxic reaction and the order of severity, after execution, check each position by operational procedure, and carry out hematology, the pathological examination of the main organs such as ALT, BUN and the heart, liver, spleen, lung, kidney, stomach;
3) through long-term feeding, all there is not toxic reaction in two groups of rats.Physically well develop.Naked eyes outward appearance and main organs no abnormality seen.Peripheral hemogram and Serum ALT, BUN and control group relatively change without pathologic.All not significant changes such as the pathological replacement heart, liver, spleen, lung, kidney, stomach, therefore, think through proved by pathology, and two kinds of nutrition are stuck with paste animal is showed without chronic toxicity.
By above two toxicity tests, prove that the nutrient powder that the present invention makes by embodiment 6 and embodiment 8 is safe, have no side effect, can be by edible for patients.
(2) lanqin oral solutions
1, clinical data: MethodsThe cases enrolled all derives from hospital clinical patient, is divided into A, B, C and tetra-groups of D at random by the 120 routine patients that meet Diagnosis of Epilepsy standard, respectively organizes case situation as shown in the table:
The each group of table 1 case situation
Illustrate: age, the course of disease, cause of disease type, the attack times of respectively organizing as can be seen from Table 1 case are learned processing there was no significant difference by statistics, have comparativity.
2, test method
A group is oral for control group gives " carbamazepine ", a 200mg, 3 times on the one; In addition, separately take placebo (without the starch of any therapeutic action, outward appearance is identical with nutrient powder of the present invention), 50g/ time, every day three times, 5 hours, interval.
It is oral that B group gives " carbamazepine ", a 200mg, 3 times on the one; In addition, separately take embodiment 6 gained nutrient powder, 50g/ time, every day three times, 5 hours, interval.
C group gives " carbamazepine " oral 200mg, 3 times on the one; In addition, separately take embodiment 8 gained nutrient powder, 50g/ time, every day three times, 5 hours, interval.
It is oral that D group gives " carbamazepine ", a 200mg, 3 times on the one; In addition, separately take embodiment 7 gained traditional Chinese medicine powder, 1g/ time (being equivalent to the contained middle dose of 50g nutrient powder), every day three times, 5 hours, interval.
Within three months, be a course for the treatment of, treat two courses for the treatment of, statistical experiment result.
3, evaluation criterion
Taking electroencephalogram or brain electrical activity mapping, seizure frequency, degree, have the improvement situations such as symptom concurrently as evaluation criterion.
4, result of the test
Through the treatment of two courses for the treatment of, result of the test is in table 2, adopts SPSS 11.0 statistics softwares to carry out statistical procedures, measurement data with mean (
) standard deviation represents, adopts t inspection, enumeration data adopts χ
2inspection.
The each group of table 2 curative effect
Illustrate: * P<0.05 compares with A group; *
$p<0.01, compares with two groups of C, D
$p<0.01.A as shown in table 2 group total effective rate is compared, and B, C, all there were significant differences for D group, and B group has utmost point significant difference.Compared with C, D group total effective rate, B group has utmost point significant difference.
The comparison of the each group of table 3 monthly average attack times
Illustrate: * P<0.05 compares with A group; *
$p<0.01, with C, two groups of $p<0.01 that compare of D, A as shown in table 3 group total effective rate is compared, and B, C, all there were significant differences for D group, and B group has utmost point significant difference.Compared with C, D group total effective rate, B group has utmost point significant difference.
Before and after the treatment of the each group of table 4 electroencephalogram patients with abnormal, compare
5, test result analysis
As shown in table 2,3,4, total effective rate, the improvement rate of B group are all significantly higher than A group, and monthly average attack times is far less than A group, and effective ratio is also far longer than A group; C group, D organize efficacy result in every respect between two groups of A, B.This presentation of results, nutrient powder of the present invention has good adjuvant treatment effect to epilepsy and intractable epilepsy; And can find out, take separately traditional Chinese medicine powder (D group) or take the nutrient powder (C group) of not adding traditional Chinese medicine ingredients, compared with A group, effect is all not remarkable; But both are combined by a certain percentage, just shown very significant adjuvant treatment effect.
Claims (5)
1. for the epileptic edible full nutrient formulation food of five cereals, it is characterized in that described food is made up of following weight portion Raw material processing: black soya bean 14-18 part, soya bean 10-14 part, shelled peanut 8-12 part, cornstarch 7-9 part, wheat bran 7-9 part, lactalbumin 5-7 part, traditional Chinese medicine powder 1.0-1.4 part, glutamic acid 0.3-0.5 part, Se-enriched yeast 0.035-0.045 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.011-0.015 part;
The traditional Chinese medicinal components of the traditional Chinese medicine powder of described food is by weight: REALGAR 16-20 part, radix bupleuri 7-11 part, Radix Angelicae Sinensis 10-14 part, root of large-flowered skullcap 12-16 part, yncaria stem with hooks 16-20 part, arisaema cum bile 11-15 part, agalloch eaglewood 13-17 part, fructus alpiniae oxyphyllae 13-17 part, rhizoma Gastrodiae 14-18 part, tuber of pinellia 7-11 part, Radix Codonopsis 8-12 part, root tuber of aromatic turmeric 10-14 part, Radix Glycyrrhizae 8-12 part, levisticum 11-15 part, ginger 8-12 part.
2. as claimed in claim 1 for the epileptic edible full nutrient formulation food of five cereals, it is characterized in that described food is made up of following weight portion Raw material processing: 16 parts, black soya bean, 12 parts of soya beans, 10 parts, shelled peanut, 8 parts of cornstarch, 8 parts of wheat brans, 6 parts of lactalbumins, 1.2 parts of traditional Chinese medicine powder, 0.4 part, glutamic acid, 0.04 part of Se-enriched yeast, 0.2 part of steviol glycoside, 0.013 part of flavoring essence.
3. as claimed in claim 1 or 2 for the edible full nutrient formulation food of five cereals of epileptic, it is characterized in that the traditional Chinese medicinal components of the traditional Chinese medicine powder of described food is: 18 parts of REALGARs, 9 parts of radix bupleuri, 12 parts of Radix Angelicae Sinensis, 14 parts of the roots of large-flowered skullcap, 18 parts of yncaria stems with hooks, 13 parts of arisaema cum bile, 15 parts of agalloch eaglewood, 15 parts of fructus alpiniae oxyphyllaes, 16 parts, rhizoma Gastrodiae, 9 parts of the tuber of pinellia, 10 parts of Radix Codonopsis, 12 parts of root tubers of aromatic turmeric, 10 parts, Radix Glycyrrhizae, 13 parts of levisticums, 10 parts, ginger.
4. the preparation method for the edible full nutrient formulation food of five cereals of epileptic as claimed in claim 1 or 2, is characterized in that comprising following processing step:
1) black soya bean, soya bean, shelled peanut, wheat bran are cleaned respectively, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: REALGAR, radix bupleuri, Radix Angelicae Sinensis, the root of large-flowered skullcap, yncaria stem with hooks, arisaema cum bile, agalloch eaglewood, fructus alpiniae oxyphyllae, rhizoma Gastrodiae, the tuber of pinellia, Radix Codonopsis, root tuber of aromatic turmeric, Radix Glycyrrhizae, levisticum, ginger, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: black soya bean, soya bean, shelled peanut, cornstarch, wheat bran, lactalbumin, traditional Chinese medicine powder, glutamic acid, Se-enriched yeast, steviol glycoside, flavoring essence, adding purified water mixes, furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) gained scattered paste shape thing makes finished product.
5. as claimed in claim 1 or 2 for the edible full nutrient formulation food of five cereals of epileptic, it is characterized in that: described food is powdery, graininess or block food, or be pasty state liquid food.
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