CN103463528B - Traditional Chinese medicine composition for treating chronic eczema - Google Patents

Traditional Chinese medicine composition for treating chronic eczema Download PDF

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CN103463528B
CN103463528B CN201310432600.0A CN201310432600A CN103463528B CN 103463528 B CN103463528 B CN 103463528B CN 201310432600 A CN201310432600 A CN 201310432600A CN 103463528 B CN103463528 B CN 103463528B
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chinese medicine
medicine composition
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CN103463528A (en
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李永全
孙胜波
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Li Yongquan
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Abstract

The invention relates to a traditional Chinese medicine composition for treating chronic eczema. The traditional Chinese medicine composition comprises the following traditional Chinese medicine materials in parts by weight: 20-40 parts of dried rehamnnia roots, 5-20 parts of tree peony barks, 5-20 parts of roots of common peony, 5-20 parts of lithospermum, 10-30 parts of rheum officinale, 5-25 parts of radix sophorae flavescentis, 5-20 parts of golden cypress, 5-20 parts of medicinal cyathula roots, 5-20 parts of broom cypress fruits, 5-25 parts of cortex dictamni, 5-20 parts of elephantopus scaber, 20-40 parts of honeysuckles, 5-25 parts of fructus forsythiae, 5-20 parts of stiff silkworms, 5-20 parts of cicada slough, 5-20 parts of Chinese parsnip roots, 10-30 parts of Chinese angelica, 20-40 parts of rhizoma smilacis glabrae, 5-25 parts of evenlobed yam rhizome, 10-30 parts of coix seeds, 20-40 parts of roots of red-rooted salvia, 10-30 parts of ligusticum wallichii, 5-20 parts of peach kernels, 5-20 parts of red flowers, 5-25 parts of schizonepeta, 10-30 parts of polygonum aviculare and 5-15 parts of liquorices. The traditional Chinese medicine composition disclosed by the invention has the effects of invigorating spleen to eliminate dampness, promoting eruption to remove skin ulcers, removing toxic materials by cooling blood, and dispelling wind and arresting itching, and has remarkable curative effect on chronic eczema and achieves reliable action.

Description

A kind of Chinese medicine composition for the treatment of chronic eczema
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic eczema.
Background technology
Eczema (eczema) be by the inside and outside factor of Various Complex cause a kind of there is pleomorphism skin lesion and easily have ooze out tendency dermal inflammatory react.Primary disease cause of disease complexity is difficult to determine more.Subjective symptoms acute pruritus.The state of an illness easily repeatedly, can be delayed and not heal for many years.Acute, subacute and chronic eczema three kinds is divided into by skin lesion characteristicness.The dermatosis that chronic eczema is feature with pruritus, speckle, squama, infiltration, plumpness, lichenification, has recurrent exerbation, is difficult to the feature of radical cure.Its clinical symptoms is: conscious violent pruritus, skin lesion pleomorphism, erythema, pimple, papulovesicle or vesicle are in flakes intensive, easily ooze out, indefinite border, is dispersed in little pimple, papulovesicle around, often accompanies erosion, incrustation, as secondary infection, can occur pustule or dense crust.At present, doctor trained in Western medicine mainly adopts antihistaminic, vitamin, hormone medicine etc. for the treatment of chronic eczema.External ointment preparation mostly is hormones ointment, although antiinflammatory, antipruritic and reduce the effect of oozing out than very fast, recurs very soon after drug withdrawal, life-time service easily causes many untoward reaction, as pachylosis, pore increase and pigmentation, therefore, there is very large drawback as conventional medicine.
The traditional Chinese medical science is thought, chronic eczema is many because natural endowment is not enough or thick greasy addicted to the pungent delicious food of food, dysfunction of the spleen in transportation, damp and hotly accumulates for a long time, impairment of YIN dryness-transformation, stasis blocking venation, and blood does not seek skin, blood-deficiency and wind-dry, and skin loses and moistens foster, strongly fragrantly falls ill in space between skin and muscles.Therefore control and should invigorating the spleen for eliminating dampness, rash to disappear skin ulcer.
According to theory of Chinese medical science, for the pathogeny of chronic eczema, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Adopt the treatment such as antihistaminic, vitamin, hormone medicine chronic eczema to there is therapeutic effect to pay no attention to and think of the large deficiency of side effect to overcome in prior art, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of chronic eczema that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic eczema, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Rehmanniae 20-40 part, Cortex Moutan 5-20 part, Radix Paeoniae Rubra 5-20 part, Radix Arnebiae (Radix Lithospermi) 5-20 part, Radix Et Rhizoma Rhei 10-30 part, Radix Sophorae Flavescentis 5-25 part, Cortex Phellodendri 5-20 part, Radix Cyathulae 5-20 part, Fructus Kochiae 5-20 part, Cortex Dictamni 5-25 part, Elephantopus scaber L. 5-20 part, Flos Lonicerae 20-40 part, Fructus Forsythiae 5-25 part, Bombyx Batryticatus 5-20 part, Periostracum Cicadae 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Smilacis Glabrae 20-40 part, Chuan Rhizoma Dioscoreae Septemlobae 5-25 part, Semen Coicis 10-30 part, Radix Salviae Miltiorrhizae 20-40 part, Rhizoma Chuanxiong 10-30 part, Semen Persicae 5-20 part, Flos Carthami 5-20 part, Herba Schizonepetae 5-25 part, Herba Polygoni Avicularis 10-30 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic eczema, it is characterized in that: its raw material of Chinese medicine and weight are: 30 parts, the Radix Rehmanniae, Cortex Moutan 12 parts, Radix Paeoniae Rubra 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Et Rhizoma Rhei 20 parts, Radix Sophorae Flavescentis 15 parts, Cortex Phellodendri 12 parts, Radix Cyathulae 10 parts, the Fructus Kochiae 10 parts, Cortex Dictamni 15 parts, Elephantopus scaber L. 10 parts, Flos Lonicerae 30 parts, Fructus Forsythiae 15 parts, Bombyx Batryticatus 10 parts, Periostracum Cicadae 10 parts, Radix Saposhnikoviae 10 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Smilacis Glabrae 30 parts, Chuan Rhizoma Dioscoreae Septemlobae 15 parts, Semen Coicis 20 parts, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Chuanxiong 20 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, Herba Schizonepetae 15 parts, Herba Polygoni Avicularis 20 parts, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Radix Paeoniae Rubra has effect of clearing away heat and cooling blood, eliminating stasis to stop pain; Radix Arnebiae (Radix Lithospermi) has effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, removing toxic substances rash; Radix Et Rhizoma Rhei has effect of pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood stasis dispelling cough-relieving; Radix Sophorae Flavescentis has effect of heat clearing and damp drying, wind dispelling insecticide; Effect that Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging removes steaming, detoxification sore treatment; Radix Cyathulae has effect of promoting blood circulation to restore menstrual flow, expelling wind and removing dampness, easing joint movement, inducing diuresis for treating stranguria syndrome; The Fructus Kochiae has effect of clearing away heat-damp and promoting diuresis relieving stranguria by diuresis; Cortex Dictamni has heat clearing and damp drying, effect of removing toxic substances of dispeling the wind; Elephantopus scaber L. has effect of heat clearing and damp drying, eliminating pathogen in the liver arresting convulsion; Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating; Fructus Forsythiae has effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Bombyx Batryticatus has effect of expelling wind for relieving convulsion, dissipating phlegm and resolving masses; Periostracum Cicadae has effect of loose wind heat extraction, rash sore-throat relieving, nebula removing spasmolytic; Effect that Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; Rhizoma Smilacis Glabrae has the effect in heat-clearing and toxic substances removing, damp eliminating diuretic, strengthening the spleen and stomach, sharp joint; Chuan Rhizoma Dioscoreae Septemlobae has dampness removing and goes effect that is turbid, wind expelling stagnation removing; Semen Coicis has effect of spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, clearing away heat and discharging pus; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Semen Persicae has effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Effect that Herba Schizonepetae has the loose wind that induces sweat, rash disappears skin ulcer; Herba Polygoni Avicularis has inducing diuresis for treating stranguria syndrome, parasite killing, antipruritic effect; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component through dialectical compatibility, help using mutually assistant, play invigorating the spleen for eliminating dampness altogether, rash disappears skin ulcer, removing pathogenic heat from blood and toxic substance from the body, dispelling wind for relieving itching effect, treating both the principal and secondary aspects of a disease is reached to the treatment of chronic eczema.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 90%, cure rate 60%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for chronic eczema, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 30g, Cortex Moutan 12g, Radix Paeoniae Rubra 10g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Et Rhizoma Rhei 20g, Radix Sophorae Flavescentis 15g, Cortex Phellodendri 12g, Radix Cyathulae 10g, Fructus Kochiae 10g, Cortex Dictamni 15g, Elephantopus scaber L. 10g, Flos Lonicerae 30g, Fructus Forsythiae 15g, Bombyx Batryticatus 10g, Periostracum Cicadae 10g, Radix Saposhnikoviae 10g, Radix Angelicae Sinensis 20g, Rhizoma Smilacis Glabrae 30g, river Rhizoma Dioscoreae Septemlobae 15g, Semen Coicis 20g, Radix Salviae Miltiorrhizae 30g, Rhizoma Chuanxiong 20g, Semen Persicae 10g, Flos Carthami 10g, Herba Schizonepetae 15g, Herba Polygoni Avicularis 20g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for chronic eczema, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 20g, Cortex Moutan 10g, Radix Paeoniae Rubra 5g, Radix Arnebiae (Radix Lithospermi) 20g, Radix Et Rhizoma Rhei 15g, Radix Sophorae Flavescentis 25g, Cortex Phellodendri 5g, Radix Cyathulae 15g, Fructus Kochiae 12g, Cortex Dictamni 25g, Elephantopus scaber L. 5g, Flos Lonicerae 40g, Fructus Forsythiae 10g, Bombyx Batryticatus 20g, Periostracum Cicadae 5g, Radix Saposhnikoviae 20g, Radix Angelicae Sinensis 15g, Rhizoma Smilacis Glabrae 40g, river Rhizoma Dioscoreae Septemlobae 5g, Semen Coicis 30g, Radix Salviae Miltiorrhizae 25g, Rhizoma Chuanxiong 30g, Semen Persicae 5g, Flos Carthami 15g, Herba Schizonepetae 25g, Herba Polygoni Avicularis 10g, Radix Glycyrrhizae 15g.
Embodiment 3
Treat a Chinese medicine composition for chronic eczema, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 25g, Cortex Moutan 20g, Radix Paeoniae Rubra 15g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Et Rhizoma Rhei 30g, Radix Sophorae Flavescentis 5g, Cortex Phellodendri 10g, Radix Cyathulae 12g, Fructus Kochiae 20g, Cortex Dictamni 5g, Elephantopus scaber L. 15g, Flos Lonicerae 25g, Fructus Forsythiae 5g, Bombyx Batryticatus 15g, Periostracum Cicadae 20g, Radix Saposhnikoviae 15g, Radix Angelicae Sinensis 10g, Rhizoma Smilacis Glabrae 25g, river Rhizoma Dioscoreae Septemlobae 10g, Semen Coicis 25g, Radix Salviae Miltiorrhizae 20g, Rhizoma Chuanxiong 25g, Semen Persicae 12g, Flos Carthami 20g, Herba Schizonepetae 5g, Herba Polygoni Avicularis 30g, Radix Glycyrrhizae 6g.
Embodiment 4
Treat a Chinese medicine composition for chronic eczema, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 35g, Cortex Moutan 5g, Radix Paeoniae Rubra 12g, Radix Arnebiae (Radix Lithospermi) 5g, Radix Et Rhizoma Rhei 25g, Radix Sophorae Flavescentis 10g, Cortex Phellodendri 20g, Radix Cyathulae 5g, Fructus Kochiae 15g, Cortex Dictamni 10g, Elephantopus scaber L. 12g, Flos Lonicerae 20g, Fructus Forsythiae 25g, Bombyx Batryticatus 5g, Periostracum Cicadae 12g, Radix Saposhnikoviae 5g, Radix Angelicae Sinensis 25g, Rhizoma Smilacis Glabrae 35g, river Rhizoma Dioscoreae Septemlobae 20g, Semen Coicis 10g, Radix Salviae Miltiorrhizae 35g, Rhizoma Chuanxiong 10g, Semen Persicae 15g, Flos Carthami 12g, Herba Schizonepetae 20g, Herba Polygoni Avicularis 15g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a Chinese medicine composition for chronic eczema, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 40g, Cortex Moutan 15g, Radix Paeoniae Rubra 20g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Et Rhizoma Rhei 10g, Radix Sophorae Flavescentis 20g, Cortex Phellodendri 15g, Radix Cyathulae 20g, Fructus Kochiae 5g, Cortex Dictamni 25g, Elephantopus scaber L. 20g, Flos Lonicerae 35g, Fructus Forsythiae 20g, Bombyx Batryticatus 12g, Periostracum Cicadae 15g, Radix Saposhnikoviae 12g, Radix Angelicae Sinensis 30g, Rhizoma Smilacis Glabrae 20g, river Rhizoma Dioscoreae Septemlobae 25g, Semen Coicis 15g, Radix Salviae Miltiorrhizae 40g, Rhizoma Chuanxiong 15g, Semen Persicae 20g, Flos Carthami 5g, Herba Schizonepetae 10g, Herba Polygoni Avicularis 25g, Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of chronic eczema given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation 80 cases, man 42 example, female 38 example, 35 ~ 55 years old age.
Two, diagnosis basis:
Chronic eczema diagnostic criteria with reference in " Chinese medical disease Standardization of diagnosis and curative effect " (publishing for 1994) that " skin cypridology " (People's Health Publisher publishes, 2002) and State Administration of Traditional Chinese Medicine are issued:
1, formed by acute differentiation, Relapse rate, the course of disease is often more than 3 months;
2, conscious pruritus, extremity, the dark red maculo-papular rash of trunk symmetry, scratch, squama covers, and partial skin is plump, coarse, in lichenification, companion's pigmentation spots;
3, skin lesion is symmetrical, has and oozes out tendency.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect:
Chronic eczema criterion of therapeutical effect with reference in " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues:
(1) fully recover: skin lesion disappears completely, subjective symptoms disappears;
(2) effective: skin lesion disappears more than 70%, and subjective symptoms is obviously improved;
(3) effective: skin lesion disappears more than 30%, and subjective symptoms makes moderate progress;
(4) invalid; Skin lesion disappears less than 30%, and subjective symptoms is not improved.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-5 the course for the treatment of, and recovery from illness 48 example, follows up a case by regular visits to and have no recurrence; Effective 15 examples, effective 9 examples, invalid 8 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1
Lin, man, 62 years old.Patient's private prosecution: played erythema, pimple, sepage without skin before obvious inducement both legs shin before 2 years, companion's pruritus, through Duo Jia hospital, the western medicines in treatment state of an illness takes a turn for the better to some extent, but has repeatedly during the left leg state of an illness.The ointment such as " Ai Luosong ", " skin-haemorrhoids-clearing " is repeatedly used nearly half a year to be coated with outward, can be antipruritic, but skin is cumulative thick, and pruritus gradually weighs.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, skin lesion is thinning, and pruritus alleviates; Continue to take 2 courses for the treatment of, skin lesion disappears completely, and subjective symptoms disappears, and cures.
Case 2:
Lee, female, 36 years old.Readme: back pruritus for many years, multi-treatment poor effect.Examine and see: the skin of back performance edemous scarlet speckle of diffusivity in various degree, obscure boundary, skin infiltration is plump, a large amount of squama, obvious scratch companion blood crusts, a little pimple.Be diagnosed as: chronic eczema.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, erythema, edema obviously reduce, without scratch and pimple; Continue to take 3 courses for the treatment of, rash block disappears, and pruritus disappears, recovery from illness.Follow up a case by regular visits to so far without recurrence.

Claims (1)

1. treat a Chinese medicine composition for chronic eczema, it is characterized in that: its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 30g, Cortex Moutan 12g, Radix Paeoniae Rubra 10g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Et Rhizoma Rhei 20g, Radix Sophorae Flavescentis 15g, Cortex Phellodendri 12g, Radix Cyathulae 10g, Fructus Kochiae 10g, Cortex Dictamni 15g, Elephantopus scaber L. 10g, Flos Lonicerae 30g, Fructus Forsythiae 15g, Bombyx Batryticatus 10g, Periostracum Cicadae 10g, Radix Saposhnikoviae 10g, Radix Angelicae Sinensis 20g, Rhizoma Smilacis Glabrae 30g, river Rhizoma Dioscoreae Septemlobae 15g, Semen Coicis 20g, Radix Salviae Miltiorrhizae 30g, Rhizoma Chuanxiong 20g, Semen Persicae 10g, Flos Carthami 10g, Herba Schizonepetae 15g, Herba Polygoni Avicularis 20g, Radix Glycyrrhizae 10g.
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CN103690835B (en) * 2014-01-07 2015-07-22 李茂林 Traditional Chinese medicine for treating infantile eczema and preparation method of traditional Chinese medicine
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CN104127564A (en) * 2014-08-11 2014-11-05 魏会珍 Traditional Chinese medicine preparation for treating chronic eczema
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