CN103432539B - Chinese herbal preparation for dispelling damp-heat and damp-toxin - Google Patents

Abstract

The invention discloses a Chinese herbal preparation for dispelling damp-heat and damp-toxin. The Chinese herbal preparation is characterized by being prepared from the following bulk drugs by weight: 60 to 150 parts of glabrous greenbrier rhizome, 50 to 80 parts of herb of Shiny Cinquefoil, 20 to 50 parts of root of Aconitum vaginatum Pritz., 20 to 50 parts of giant knotweed rhizome, 20 to 50 parts of lightyellow sophora root, 10 to 40 parts of white mustard seed, 20 to 50 parts of common cnidium fruit, 50 to 100 parts of imperata rhizome, 30 to 50 parts of cassia twig, 50 to 100 parts of milkvetch root, 10 to 20 parts of divaricate saposhnikovia root, 10 to 40 parts of bighead atractylodes rhizome, 10 to 20 parts of dried ginger and 10 to 20 parts of liquorice root. The Chinese herbal preparation can dispel wind and dampness, remove toxin, alleviate itching, recover yang, tonify qi and dredge and wash Shuidao, has fast action and a good curative effect on damp-heat and damp-toxin and exerts a good therapeutic effect on fever and hand-foot-and-mouth diseases caused by damp-heat and damp-toxin, pruritus at private parts of males and females, eczema on the skin, tinea scars, ulcer, herpes, morbid leucorrhea caused by damp-heat, etc.

Description

The Chinese medicine preparation of the damp and hot noxious dampness of a kind of Eradicates

Technical field

The invention belongs to field of Chinese herbal medicine technology, be specifically related to the Chinese medicine preparation of the damp and hot noxious dampness of a kind of Eradicates.

Background technology

Endogenous dampness is a kind of pathological product, normal relevant with digestive function.The traditional Chinese medical science thinks the function that spleen has " transmitting and distributing the fluids ", if the empty dyspepsia of body or eating and drinking too much at one meal, eats too much greasy, sweet food, then spleen just can not normal transporting and make " retention of water-damp in the body "; And insufficiency of the spleen people also easily causes the invasion of exogenous damp, exogenous damp is also normal to be made wet from interior life, so both are not only independent but also associate because hindering taste.Heat in damp and hot is with wet simultaneous, or because of the hot weight in wet base in summer and autumn sky, wetly invades human body with heat seal, or because of wet stay for a long time except and heat-transformation, or make to wet " heat being transformed from excessive YANG " because of " positive hot body matter ", therefore, wet and hot to exist be very common simultaneously.

Damp and hot generally shows as: limbs are heavy, and heating is many obviously afternoon, does not alleviate because of perspiration; Yellowish fur, rapid pulse.Concrete manifestation has difference because of different position, damp and hot place: be then eczema or furuncle bleb at skin and flesh; At joint muscle arteries and veins then partial gall.But usually said damp and hot finger damp and hotly gos deep into internal organs more, and particularly taste is damp and hot, the vexed abdominal distention of visible gastral cavity, anorexia of feeling sick, and just rare, short urination is red, wiry and frequent pulse; Other show as liver pain as dampness-heat in the liver and gallbladder, and bitter taste appetite is poor, or the jaundice of body order, or heating is afraid of cold alternately, wiry and frequent pulse; Damp-heat in the urinary bladder is shown in frequent micturition, urgent micturition, less puckery and pain: yellow skin is turbid; Damp-heat in the large intestine is shown in abdominal pain diarrhea, even tenesmus, rushes down defecation with blood and pus just, burning sensation of the anus, thirsty.

Noxious dampness refers to that dampness smoulders and with the passing of time becomes poison, and noxious dampness amasss bets in intestinal, can cause " noxious dampness is had blood in stool ", and disease sees that feces has blood and slime, or has blood in stool and color is purple dark not fresh, but abdomen is not bitterly; If noxious dampness bet, strongly fragrant in skin, then calf easily raw carbuncle sore, be called " multiple abscesses due to noxious dampness ", disease is seen that skin ulcer shape is flat and is collapsed, and root foot is unrestrained swollen, and bag is blue or green or purple black, and after diabrosis, pus dipping spreads, and does not close up for a long time.

The existing people for damp-heat constitution improves the medicine of its symptom at present, as SHIDUQING PIAN, has blood enriching and dryness moistening, removing dampness is detoxified, dispelling wind for relieving itching, belongs to that blood deficiency is wet accumulates skin card person for skin pruritus, this medicine does not have multiple positive QI invigorating, effect that tonneau water channel effects a permanent cure, and therapeutic effect is also not obvious.

Summary of the invention

For solving the problems referred to above that prior art exists, the object of the present invention is to provide one to have except wind dehumidifying, removing toxic substances is controlled and is itched, multiple positive QI invigorating, logically washs water channel, and it is rapid-action to treat damp and hot noxious dampness, good effect, the Chinese medicine preparation of the damp and hot noxious dampness of the Eradicates effected a permanent cure.

For achieving the above object, the technical solution used in the present invention: the Chinese medicine preparation of the damp and hot noxious dampness of this Eradicates, is characterized in that being prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 60-150 part, Herba potentillae fulgentis 50-80 part, Radix Aconiti Vaginati 20-50 part, Rhizoma Polygoni Cuspidati 20-50 part, Radix Sophorae Flavescentis 20-50 part, Semen Sinapis Albae 10-40 part, Fructus Cnidii 20-50 part, Rhizoma Imperatae 50-100 part, Ramulus Cinnamomi 30-50 part, Radix Astragali 50-100 part, Radix Saposhnikoviae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Rhizoma Zingiberis 10-20 part, Radix Glycyrrhizae 10-20 part.

Preferably, the Chinese medicine preparation of the damp and hot noxious dampness of this Eradicates, is prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 100 parts, Herba potentillae fulgentis 60 parts, Radix Aconiti Vaginati 30 parts, Rhizoma Polygoni Cuspidati 30 parts, Radix Sophorae Flavescentis 30 parts, Semen Sinapis Albae 30 parts, Fructus Cnidii 30 parts, Rhizoma Imperatae 50 parts, Ramulus Cinnamomi 30 parts, the Radix Astragali 50 parts, Radix Saposhnikoviae 10 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Zingiberis 10 parts, 10 parts, Radix Glycyrrhizae.

Preparation method: above-mentioned raw materials medicine is made according to a conventional method other dosage forms such as pill, tablet, capsule and decoction.

Adopt the beneficial effect of technique scheme: this blood fat-reducing blood pressure-decreasing Chinese medicine decoction, with Rhizoma Smilacis Glabrae, Herba potentillae fulgentis, Radix Aconiti Vaginati, Rhizoma Polygoni Cuspidati for monarch drug, diuretic, separates blood system hundred poison, anticancer.With Radix Sophorae Flavescentis, Semen Sinapis Albae, Fructus Cnidii, Radix Saposhnikoviae for ministerial drug, except wind, dehumidifying, control and itch, anticancer.With the Radix Astragali, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Rhizoma Imperatae, Rhizoma Zingiberis for adjuvant drug, multiple positive QI invigorating, dampness, leads to and washs water channel.Radix Glycyrrhizae, for making, is concocted all medicines, steadily uses sequence.Said medicine is worked in coordination with mutually, and have except wind dehumidifying, removing toxic substances is controlled and itched, multiple positive QI invigorating, logically washs water channel, and the heating caused because of above-mentioned reason, hand-foot-mouth disease, male and female pudendum pruritus, skin eczema, tinea scar carbuncle, herpes, the inferior disease of humid tropics.

Rhizoma Smilacis Glabrae: cure mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, treats furuncle, carbuncle, scrofula, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.There is antitumor Detoxication.

Herba potentillae fulgentis: another name: kind white leaf (" the southern regions of the Yunnan Province book on Chinese herbal medicine "), turn over white Radix Sanguisorbae, Semen Arecae core (" the southern regions of the Yunnan Province book on Chinese herbal medicine " arranges this), turn over back of the body Pennisetum centrasiaticum Tzvel.Heat clearing and inflammation relieving, cooling blood for hemostasis, cures mainly: control dysentery, enteritis, and stomachache, hemoptysis of pulmonary tuberculosis, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, furuncle.

Radix Aconiti Vaginati: " Guizhou folk medicine ": warm in nature, acrid in the mouth, slightly poisonous.Cure mainly: control cough with asthma, menoxenia, traumatic injury.

Rhizoma Polygoni Cuspidati: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis does not Xia ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.

Radix Sophorae Flavescentis: cure mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.

Semen Sinapis Albae, acrid in the mouth, warm in nature; Attach to the lung and stomach meridians; Pungent row falls apart, and has eliminating phlegm promoting the circulation of QI, and warming the meridian is except cold, and effect of eliminating stagnation edema, cure mainly cough with asthma abundant expectoration, fullness in the chest and hypochondriac pain, cold syndrome of the stomach tells food, numb limbs and tense tendons, arthralgia due to cold-dampnes, tuberculosis scrofula, multiple abscess caused by damp-phlegm, carbuncle of yin nature toxic swelling.

Fructus Cnidii: warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago.

Rhizoma Imperatae: cure mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing.For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat is vomitted the sound of vomiting, coughs.

Ramulus Cinnamomi: expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI.Main exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; Extreme cold of the limbs; Amenorrhea dysmenorrhea; Lump in the abdomen lumps; The thoracic obstruction; Cardiopalmus; Phlegm retention; Dysuria.

The Radix Astragali: have effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Modern medicine study shows, the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging." Radix Astragali and Radix Ginseng, Radix Glycyrrhizae three taste, for removing the panacea scorching, flesh is warm.Taste one are empty, and lung qi first absolutely, must be used Radix Astragali temperature boundary between muscles, beneficial fur, real space between skin and muscles, not make sweating, mend three Jiao with beneficial vigour." (drawing from Compendium of Material Medica).

Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.Cure mainly: affection of exogenous wind-cold; Headache general pain; Rheumatic arthralgia; Joint is ached; Stomachache is had loose bowels; Discharging fresh blood stool; Tetanus; Rubella pruritus; Skin infection from the beginning of.Calmness, antiinflammatory, anti-allergic effects.

The Rhizoma Atractylodis Macrocephalae has air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive effect, is the common medicine of air making-up and spleen enlivening, phlegm retention edema." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, quench the thirst, antiabortive.”

The negative characteristics of damp and hot noxious dampness patient can effectively be alleviated or eliminate to Chinese medicine preparation provided by the invention,

The Experiment on therapy data of several classical symptom are provided to be illustrated below:

(1), for easy fecula thorn, furuncle symptom.

1, experimental technique:

1.1 experimental grouies take the decoction that the embodiment of the present invention 1 provides, 2 times on the one, a 200ml, and Combined with Exercise Therapy and diet are treated

Method; Matched group takes dehumidifying medicine Combined with Exercise Therapy and dietetic therapy.Two groups equal 15 days be 1 course for the treatment of, terminate rear evaluation curative effect the course for the treatment of.

Compare before 1.2 treatments:

Experimental group: totally 50 people, male 29 people, female 21 people, 25-50 age, 30 people year, 51-75 year 20 people.

Matched group: totally 50 people, male 30 people, female 20 people, 25-50 age, 28 people year, 51-75 year 22 people.

Check through X2 for more than 1.3 each groups, difference that there are no significant, experimental group and the front disease for the treatment of of control group plant there was no significant difference.

2. criterion of therapeutical effect and assessment method:

Detect the items such as inspection mark according to symptom, sign, meridians.Effective: fundamental symptoms disappears, meridians detect and check that lung meridian, tri-jiao channel index are shown in green, are tending towards normal; Effective: fundamental symptoms obviously improves, meridians detect and check lung meridian, tri-jiao channel index is shown as indigo plant, yellow; Invalid: fundamental symptoms does not change, meridians detect and check that lung meridian, tri-jiao channel index are shown in red.

3. therapeutic outcome:

Between group, total effects compares and sees the following form, and Ridit assay shows, between matched group and treatment group, total effects has significant difference, and experimental group total effective rate is 88.0%, is obviously better than matched group 60.0%, and prompting experimental group curative effect is better. 。

[0029](2) other symptoms.

1. clinical manifestation

Eczema or furuncle bleb; The vexed abdominal distention of gastral cavity, bitter taste, there is abnormal flavour in the mouth; Short urination is red, women's leucorrhea with yellow discharge, the moist hyperhidrosis of males scrotum.

2. experimental technique.

2.1 experimental grouies take the decoction that the embodiment of the present invention 1 provides, 2 times on the one, a 200ml, Combined with Exercise Therapy and dietetic therapy; Matched group is not taken any medicine, is not carried out any motion.Two groups equal 7 days be 1 course for the treatment of, 2 courses for the treatment of terminate rear evaluation curative effect.

Comparability inspection before 2.2 treatments.

Experimental group: totally 145 people, male 95 people, female 50 people, 25-50 age, 85 people year, 51-75 year 60 people.

Matched group: totally 150 people, male 105 people, female 45 people, 25-50 age, 98 people year, 51-75 year 52 people.

Before 2.3 experimental grouies and treatment of control group, sex difference is without significance.Check through X2 for each group above, difference that there are no significant.

3. criterion of therapeutical effect and assessment method.

Mark according to the item such as symptom, sign.Effective: symptom is obviously improved or eliminated; Effective: symptom is improved; Invalid: not meet above standard person.

4, therapeutic outcome.

Between group, total effects compares and sees the following form, and Ridit assay shows, between matched group and treatment group, total effects has significant difference, and treatment group total effective rate is 85.7%, is obviously better than matched group 53.2%, and prompting experimental group curative effect is better.

Group	Number	Effective	Effectively	Invalid	Total effective rate %
						Treatment group	145	105	25	15	89.7
Matched group	150	65	16	69	54.0

Treatment group therapeutic efficiency is higher, and prompting treatment group curative effect is better.In addition, have no obvious adverse reaction and occur, illustrate that this product is without any side effects, safe and reliable.

(3) clear noxious dampness capsule for treating genital herpes clinical observation

180 routine patients are treated, 19 ~ 45 years old age, average 31.2 ± 2.4 years old; The course of disease 3 days ~ 1 year.All cases did not use Drug therapy in 2 weeks, without other sexually transmitted disease (STD)s.

Criterion of therapeutical effect: by sings and symptoms as erythema, pimple, vesicle, erosion, shallow table ulcer, the having that it's too late light and heavy degree score is 0 ~ 3 point, according to integral and calculating therapeutic index before and after treatment of pain or pruritus: therapeutic index=(before treating after integration-treatments integration)/treat rear integration × 100%.Recovery from illness is therapeutic index > 95%; Effective is therapeutic index > 70%; Be effectively therapeutic index > 30%; Invalid is therapeutic index < 30%.Total effective rate adds effective statistics with recovery from illness.

Therapeutic Method: the decoction that the oral embodiment of the present invention 1 provides, each 200ml, every day 2 times, serveing on 15 days is 1 course for the treatment of, adds up curative effect after 1 course for the treatment of.Treatments period forbidding other drug.All patients carry out blood, routine urinalysis, hepatic and renal function detection before and after treatment.

Result:

Untoward reaction is observed: have no all patients of obvious adverse reaction blood, routine urinalysis, hepatic and renal function before and after treatment and detect and show no obvious abnormalities change.

Detailed description of the invention

Embodiment 1

The Chinese medicine preparation of the damp and hot noxious dampness of this Eradicates, is prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 60 parts, Herba potentillae fulgentis 50 parts, Radix Aconiti Vaginati 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Sophorae Flavescentis 20 parts, Semen Sinapis Albae 10 parts, Fructus Cnidii 20 parts, Rhizoma Imperatae 50 parts, Ramulus Cinnamomi 30 parts, the Radix Astragali 50 parts, Radix Saposhnikoviae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Rhizoma Zingiberis 10 parts, 10 parts, Radix Glycyrrhizae.

Preparation method: above-mentioned raw materials medicine is made according to a conventional method other dosage forms such as pill, tablet, capsule and decoction.

Embodiment 2

The Chinese medicine preparation of the damp and hot noxious dampness of this Eradicates, is prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 100 parts, Herba potentillae fulgentis 60 parts, Radix Aconiti Vaginati 30 parts, Rhizoma Polygoni Cuspidati 30 parts, Radix Sophorae Flavescentis 30 parts, Semen Sinapis Albae 30 parts, Fructus Cnidii 30 parts, Rhizoma Imperatae 50 parts, Ramulus Cinnamomi 30 parts, the Radix Astragali 50 parts, Radix Saposhnikoviae 10 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Zingiberis 10 parts, 10 parts, Radix Glycyrrhizae.

Preparation method: above-mentioned raw materials medicine is made according to a conventional method other dosage forms such as pill, tablet, capsule and decoction.

Embodiment 3

The Chinese medicine preparation of the damp and hot noxious dampness of this Eradicates, is prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 150 parts, Herba potentillae fulgentis 80 parts, Radix Aconiti Vaginati 50 parts, Rhizoma Polygoni Cuspidati 50 parts, Radix Sophorae Flavescentis 50 parts, Semen Sinapis Albae 40 parts, Fructus Cnidii 50 parts, Rhizoma Imperatae 100 parts, Ramulus Cinnamomi 50 parts, the Radix Astragali 100 parts, Radix Saposhnikoviae 20 parts, the Rhizoma Atractylodis Macrocephalae 40 parts, Rhizoma Zingiberis 20 parts, 20 parts, Radix Glycyrrhizae.

Preparation method: above-mentioned raw materials medicine is made according to a conventional method other dosage forms such as pill, tablet, capsule and decoction.

Claims (2)

1. a Chinese medicine preparation for the damp and hot noxious dampness of Eradicates, is characterized in that being prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 60-150 part, Herba potentillae fulgentis 50-80 part, Radix Aconiti Vaginati 20-50 part, Rhizoma Polygoni Cuspidati 20-50 part, Radix Sophorae Flavescentis 20-50 part, Semen Sinapis Albae 10-40 part, Fructus Cnidii 20-50 part, Rhizoma Imperatae 50-100 part, Ramulus Cinnamomi 30-50 part, Radix Astragali 50-100 part, Radix Saposhnikoviae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Rhizoma Zingiberis 10-20 part, Radix Glycyrrhizae 10-20 part.

2. the Chinese medicine preparation of the damp and hot noxious dampness of Eradicates as claimed in claim 1, is characterized in that being prepared from by the crude drug of following weight parts: Rhizoma Smilacis Glabrae 100 parts, Herba potentillae fulgentis 60 parts, Radix Aconiti Vaginati 30 parts, Rhizoma Polygoni Cuspidati 30 parts, Radix Sophorae Flavescentis 30 parts, Semen Sinapis Albae 30 parts, Fructus Cnidii 30 parts, Rhizoma Imperatae 50 parts, Ramulus Cinnamomi 30 parts, the Radix Astragali 50 parts, Radix Saposhnikoviae 10 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Zingiberis 10 parts, 10 parts, Radix Glycyrrhizae.