CN103432509B - The topical agent for the treatment of prolapse of lumbar intervertebral disc - Google Patents

The topical agent for the treatment of prolapse of lumbar intervertebral disc Download PDF

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CN103432509B
CN103432509B CN201310303758.8A CN201310303758A CN103432509B CN 103432509 B CN103432509 B CN 103432509B CN 201310303758 A CN201310303758 A CN 201310303758A CN 103432509 B CN103432509 B CN 103432509B
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radix
rhizoma
intervertebral disc
prolapse
lumbar intervertebral
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CN201310303758.8A
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CN103432509A (en
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郭立新
刘新丽
张岩
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Abstract

The present invention relates to field of traditional Chinese medicine formula, specifically a kind of topical agent for the treatment of prolapse of lumbar intervertebral disc, it is characterized in that crude drug composition with parts by weight is, Radix Notoginseng powder 15 ~ 20, Herba speranskiae tuberculatae 10 ~ 15, Scorpio 8 ~ 12, Scolopendra 10 ~ 12, Pheretima 10 ~ 15, Sanguis Draxonis 6 ~ 10, Rhizoma Chuanxiong 20 ~ 25, Rhizoma Drynariae 6 ~ 8, Radix Stephaniae Tetrandrae 10 ~ 12, Cortex erythrinae 12 ~ 15, Fructus Chaenomelis 15 ~ 20, the Cortex Eucommiae 8 ~ 10, Lignum Sappan 12 ~ 16, Radix Dipsaci 6 ~ 10, Rhizoma Cibotii 15 ~ 20, the Radix Aucklandiae 11 ~ 13, Radix Et Rhizoma Rhei 12 ~ 14, Fructus Gardeniae 15 ~ 18, Semen Persicae 9 ~ 12, Rhizoma Alismatis 10 ~ 14, Cortex Phellodendri 14 ~ 18, Rhizoma Curcumae Longae 16 ~ 18, Radix Paeoniae Rubra 12 ~ 16, add medical alcohol after being pulverized by above-mentioned 23 taste crude drug to soak, filter to get filtrate.It is high that the present invention treats Lumbar Intervertebral Disc, the vertebral pulp that can bounce back, repair break fibrous ring atrophy, dissolve outstanding intervertebral disc.

Description

The topical agent for the treatment of prolapse of lumbar intervertebral disc
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of topical agent being used for the treatment of prolapse of lumbar intervertebral disc.
Background technology
As everyone knows, intervertebral disc prolapse is because of degeneration of intervertebral disc, Anular disruption, Nucleus pulposus stimulates or pressuring neural root, cauda equina nerve show a kind of syndrome, is one of modal reason of lumbago and skelalgia.With waist 4 ~ 5, waist 5 ~ sacrum in prolapse of lumbar intervertebral disc 1gap sickness rate is the highest, accounts for 90% ~ 96%, and multiple intervertebral space is sent out patient simultaneously and only accounted for 5% ~ 22%.Degeneration of intervertebral disc is Fundamentals, and increase with the age, fibrous ring and vertebral pulp water content reduce gradually, and vertebral pulp tension force is declined, and intervertebral disc is thinning.Meanwhile, hyaluronic acid and keratinization sulfate reduce, and low-molecular-weight glycoprotein increases, and fibre modification and Collagen fiber deposition increase, and vertebral pulp follows the string, and intervertebral disc structure relaxes, cartilaginous lamina cystis degeneration.Outside after the fibrous ring supported not having posterior longitudinal ligament, these changes are more obvious, occur centration rimala.
In whole intervertebral disc, lumbar intervertebral disc is stressed maximum, the most easily pathological changes occurs.The basic reason of prolapse of lumbar intervertebral disc is the Anular disruption of lumbar intervertebral disc, causes vertebral pulp to be given prominence to from rent, and is urged to the nerve root on side, cause nerve root edema, adhesion, thus produces the series of symptoms such as lumbago, lower limb fiber crops.Clinical treatment prolapse of lumbar intervertebral disc, traditional remedies comprises: take the modes such as analgesic, physical therapy, operation, but these all can not be treated for old complaint.That is, the basic reason " fibrous ring of breaking " of prolapse of lumbar intervertebral disc is not repaired.
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, a kind of topical agent for the treatment of prolapse of lumbar intervertebral disc is provided, cost is low, treatment intervertebral disc prolapse curative effect is high, have no side effect, there is the cold expelling that induces sweat, expelling wind and removing dampness, disperse blood stasis and dredge collateral, can remove nerve root compression, retraction vertebral pulp, quickly alleviating pain, only fiber crops, repair break fibrous ring atrophy, dissolve outstanding intervertebral disc, deal with problems from source.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of topical agent for the treatment of prolapse of lumbar intervertebral disc, it is characterized in that crude drug composition with parts by weight is, Radix Notoginseng powder 15 ~ 20, Herba speranskiae tuberculatae 10 ~ 15, Scorpio 8 ~ 12, Scolopendra 10 ~ 12, Pheretima 10 ~ 15, Sanguis Draxonis 6 ~ 10, Rhizoma Chuanxiong 20 ~ 25, Rhizoma Drynariae 6 ~ 8, Radix Stephaniae Tetrandrae 10 ~ 12, Cortex erythrinae 12 ~ 15, Fructus Chaenomelis 15 ~ 20, the Cortex Eucommiae 8 ~ 10, Lignum Sappan 12 ~ 16, Radix Dipsaci 6 ~ 10, Rhizoma Cibotii 15 ~ 20, the Radix Aucklandiae 11 ~ 13, Radix Et Rhizoma Rhei 12 ~ 14, Fructus Gardeniae 15 ~ 18, Semen Persicae 9 ~ 12, Rhizoma Alismatis 10 ~ 14, Cortex Phellodendri 14 ~ 18, Rhizoma Curcumae Longae 16 ~ 18, Radix Paeoniae Rubra 12 ~ 16, add medical alcohol after being pulverized by above-mentioned 23 taste crude drug to soak, filter to get filtrate.
Cost of the present invention is low, treatment intervertebral disc prolapse curative effect is high, have no side effect, there is the cold expelling that induces sweat, expelling wind and removing dampness, disperse blood stasis and dredge collateral, can remove nerve root compression, retraction vertebral pulp, quickly alleviating pain, only fiber crops, repair break fibrous ring atrophy, dissolve outstanding intervertebral disc, deal with problems from source.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
The present embodiment uses the crude drug of following weight proportion for a dose of medicine: adopt Radix Notoginseng powder 18 grams, Herba speranskiae tuberculatae 12 grams, Scorpio 10 grams, Scolopendra 11 grams, Pheretima 12 grams, Sanguis Draxonis 8 grams, Rhizoma Chuanxiong 22 grams, Rhizoma Drynariae 7 grams, Radix Stephaniae Tetrandrae 11 grams, Cortex erythrinae 13 grams, Fructus Chaenomelis 12 grams, the Cortex Eucommiae 9 grams, Lignum Sappan 14 grams, Radix Dipsaci 8 grams, Rhizoma Cibotii 17 grams, the Radix Aucklandiae 12 grams, Radix Et Rhizoma Rhei 13 grams, Fructus Gardeniae 16 grams, 10 grams, Semen Persicae, Rhizoma Alismatis 12 grams, Cortex Phellodendri 16 grams, 17 grams, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 14 grams, medical alcohol is added after being pulverized by above-mentioned 23 taste crude drug, the addition of ethanol there just be not powder to be advisable with ethanol, soak and filter to get filtrate after 30 days.Every day puts examination lumbar vertebra position on the skin with gauze dip in liquid medicine, each medicinal liquid using 150 milliliters, and a course for the treatment of was four week, used two courses for the treatment of continuously.
Radix Notoginseng powder of the present invention has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, and tumbling down swells and ache; Herba speranskiae tuberculatae cures mainly arthritis, pyretic toxicity, has pungent loose temperature function, expelling wind and dampness, promoting blood circulation and stopping pain, holds concurrently and can to disappear painful abdominal mass by softening the hard mass; Scorpio has the effects such as endogenous wind stopping relieving convulsion, dredge the meridian passage, reducing swelling and alleviating pain, dispersing pathogen accumulation, can treat rheumatic arthralgia, hemiplegia, apoplexy, scrofula, nameless gall, cancer, refractory skin etc.; Scolopendra is warm in nature, acrid in the mouth, poisonous.There is the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, apoplexy facial hemiparalysis, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom; Pheretima heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis, twitches for unconsciousness due to high fever infantile convulsion, and joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension; Sanguis Draxonis has promoting blood circulation to remove blood stasis, analgesic therapy, effect of hemostasia and promoting granulation; Rhizoma Chuanxiong is suitable for the various disease of stagnation of blood stasis, wind-expelling pain-stopping, and effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia; Rhizoma Drynariae bitter in the mouth, warm in nature, return kidney, Liver Channel, gas perfume (or spice) falls loose, mends and row of holding concurrently, has replenishing kidney, strengthening waist, promoting blood circulation and stopping pain, effect of reunion of fractured tendons and bones, cure mainly lumbago due to renal deficiency; Radix Stephaniae Tetrandrae has effect of inducing diuresis to remove edema, wind-expelling pain-stopping.To harness the river swollen tympanites, hygropyretic beriberi, brothers' spasm and pain, tinea; Cortex erythrinae wind-damp dispelling, the meridian dredging, parasite killing.Dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies; Fructus Chaenomelis sour in the mouth warm in nature, suppressing the hyperactive liver and easing the stomach, relaxing muscles and tendons network, muscles and bones of living, blood pressure lowering; Cortex Eucommiae sweet in the mouth, warm in nature.Return liver, kidney, stomach warp.Liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive.The lumbago and skelalgia or aching and limp unable that treatment insufficiency of kidney-YANG causes.Born of the same parents' tire that deficiency of liver-QI causes is not solid, scrotum pruritus due to damp pathogen; Lignum Sappan can promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving.Clinical being usually used in controls married woman's vim and vigour cardiac and abdominal pain, amenorrhea; Radix Dipsaci invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous injured, only metrorrhagia.For aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer swell; Rhizoma Cibotii wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, restrains astringent or styptic treatment for spontaneous sweating.Application arthromyodynia, lumbago back rigidity, sufficient knee joint withers weak, the enuresis, seminal emission, leukorrhagia; The pain relieving of Radix Aucklandiae warming middle-JIAO to promote flow of QI, strengthening the spleen to promote digestion intestinal stasis relieving.Cure mainly feeling of stuffiness in chest hypochondriac pain, abdominal distention, heavy after dysentery, accumulation of food in the stomach and intes tine due to indigestion, vomiting is had loose bowels, and colic of cold type is suffered from abdominal pain, edema, foot gas; Radix Et Rhizoma Rhei has attacks the effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances; Fructus Gardeniae has the effect such as clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, jaundice, stranguria with blood pain puckery, the red and swollen pain of order, fire-toxin skin ulcer, blood pressure lowering; Semen Persicae has blood stasis removing and clots absorbing, moisturizes effect of laxation, controls amenorrhea, dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, traumatic injury, dryness of the intestine constipation; Rhizoma Alismatis diuretic, eliminating dampness by diuresis, expels the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria; Cortex Phellodendri hygropyretic dysentery, has loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema; The circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia.For the twinge of the breast side of body, amenorrhea , WEIJIA, rheumatism shoulder arm pain, tumbling and swelling; Radix Paeoniae Rubra has the functions such as clots absorbing, pain relieving, removing heat from blood, detumescence, controls the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, suffers from abdominal pain, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize, and its processing method is identical with embodiment one.
Below in conjunction with my clinic, the clinical trial that namely Guo Shi Academy of Traditional Chinese Medicine in In Shandong Weihai carries out is done further the present invention, is described in detail:
1, case selection: this group 60 example, age 38-65 year, wherein male 49 people, women 11 people, all cases is all the prolapse of lumbar intervertebral disc that degree is different.
2, Therapeutic Method:
Every day puts examination lumbar vertebra position on the skin with gauze dip in liquid medicine, each medicinal liquid using 150 milliliters, and a course for the treatment of was four week, used two courses for the treatment of continuously.
3, diagnostic criteria: (1) has waist wound, chronic strain or is subject to cold-damp history.Major part patient has chronic back pain history at premorbid.(2) often person between twenty and fifty are betided.(3) lumbago is to buttocks and lower limb radiation, and when abdominal pressure increases (as cough, sneeze), pain increases the weight of.(4) scoliosis, waist physiologic radian disappears, and diseased region vertebra is other tenderness, and to lower limb radiation, waist limitation of activity.(5) the lower limb innervation district that gets involved feels or blunt, and course of disease elder can occur amyotrophy leg raising straight or strengthen test positive, and knee joint, Achilles tendon reflex weaken or disappear, and big toe dorsiflexion power weakens.(6) sheet inspection taken the photograph by x line: scoliosis, and waist physiology lordosis disappears, and neighboring edge has osteophytosis.Ct, mri check position and the degree that can show intervertebral disk hernia.
4, efficacy evaluation: (1) cures: lumbago and skelalgia disappears, leg raising straight more than 70 degree, the extensive recovery operation of energy, can walk more than 2 kilometers.(2) take a turn for the better: lumbago and skelalgia alleviates, waist movable function improves.(3) do not heal: symptom, sign are without improvement
3, therapeutic effect: use the present invention treats 60 examples altogether, cures 18 examples, takes a turn for the better 40, and do not heal 2 examples, and effective percentage is 97%, and inefficiency is 3%.

Claims (1)

1. treat the topical agent of prolapse of lumbar intervertebral disc for one kind, it is characterized in that: crude drug composition with parts by weight is, Radix Notoginseng powder 15 ~ 20, Herba speranskiae tuberculatae 10 ~ 15, Scorpio 8 ~ 12, Scolopendra 10 ~ 12, Pheretima 10 ~ 15, Sanguis Draxonis 6 ~ 10, Rhizoma Chuanxiong 20 ~ 25, Rhizoma Drynariae 6 ~ 8, Radix Stephaniae Tetrandrae 10 ~ 12, Cortex erythrinae 12 ~ 15, Fructus Chaenomelis 15 ~ 20, the Cortex Eucommiae 8 ~ 10, Lignum Sappan 12 ~ 16, Radix Dipsaci 6 ~ 10, Rhizoma Cibotii 15 ~ 20, the Radix Aucklandiae 11 ~ 13, Radix Et Rhizoma Rhei 12 ~ 14, Fructus Gardeniae 15 ~ 18, Semen Persicae 9 ~ 12, Rhizoma Alismatis 10 ~ 14, Cortex Phellodendri 14 ~ 18, Rhizoma Curcumae Longae 16 ~ 18, Radix Paeoniae Rubra 12 ~ 16, add medical alcohol after being pulverized by above-mentioned 23 taste crude drug to soak, filter to get filtrate.
CN201310303758.8A 2013-07-10 2013-07-10 The topical agent for the treatment of prolapse of lumbar intervertebral disc Expired - Fee Related CN103432509B (en)

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CN103720973B (en) * 2014-01-02 2016-08-17 陈洪瑜 A kind of Chinese herbal medicine treating prolapse of lumbar intervertebral disc and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146343A (en) * 1995-09-25 1997-04-02 石建民 External compress paste for discopathy
CN1895642A (en) * 2005-07-12 2007-01-17 侯保君 Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method
CN101293041A (en) * 2008-06-18 2008-10-29 张景燕 Externally used medicament for treating protrusion of lumbar vertebral disc, spinal canal stenosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146343A (en) * 1995-09-25 1997-04-02 石建民 External compress paste for discopathy
CN1895642A (en) * 2005-07-12 2007-01-17 侯保君 Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method
CN101293041A (en) * 2008-06-18 2008-10-29 张景燕 Externally used medicament for treating protrusion of lumbar vertebral disc, spinal canal stenosis

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