CN103432397B - Traditional Chinese medicine effective part composition for treating thromboangiitis obliterans - Google Patents
Traditional Chinese medicine effective part composition for treating thromboangiitis obliterans Download PDFInfo
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- CN103432397B CN103432397B CN201310358200.XA CN201310358200A CN103432397B CN 103432397 B CN103432397 B CN 103432397B CN 201310358200 A CN201310358200 A CN 201310358200A CN 103432397 B CN103432397 B CN 103432397B
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- thromboangiitis obliterans
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Abstract
The invention discloses a traditional Chinese medicine effective part composition for treating thromboangiitis obliterans. The traditional Chinese medicine effective part composition comprises the following raw materials according to certain parts by weight: perilla frutescens, bletilla striata, trametes versicolor, Chinese photinia leaves, lance asiabell root and beautyberry leaf. The traditional Chinese medicine effective part composition has the effects of warming channel to remove coldness, promoting blood circulation to remove meridian obstruction, promoting the circulation of qi to disperse blood stasis, clearing heat to promote diuresis, detoxicating to relieve pain, tonifying Qi and nourishing blood, and has obvious curative effects, no negative side effect and high security in treatment of thromboangiitis obliterans.
Description
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition being used for the treatment of thromboangiitis obliterans.
Background technology
Thromboangiitis obliterans, has another name called spontaneous gangrene, is a kind of more common chronic progressive external angiopathy.Clinical main manifestations is skin color and the temperature change of sick lower limb vein, intermittent claudication, stationary pain, and severe patient can complicated by ulcer, gangrene, the most easily suffers from male adults.Modern Western medicine there is no unified understanding so far to vasculitic pathogeny, it is generally acknowledged how closely related with sympathetic nerve function disorder and autoimmune response etc.The risk factor that smoking room is generally acknowledged at present both at home and abroad.In addition, cold, humidity, infection, wound etc. can become potential inducement.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation for the treatment of thromboangiitis obliterans, this active component composition can treat thromboangiitis obliterans, and not easily recurs.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The primary disease cause of disease and diseases caused by exogenous pathogenic factor cold-damp, eating and drinking without temperance, seven emotions cross pole or sexual strain, and prolonged illness deficiency in origin etc. are relevant.The current traditional Chinese medical science is summarized as yang-energy weakness, cold blood stasis, turbid damp pents up, the venation that is hampered, the hepatic and renal YIN deficiency, excessive noxious heat, asthenia of qi and blood lose, channels stasis blocking.
Treat a Chinese medicinal effective-part composition for thromboangiitis obliterans, be made up of the following raw material according to mass fraction meter: Fructus Perillae Frutescentis 26, the Pseudobulbus Bletillae (Rhizoma Bletillae) 21, Coriolous Dersicolor (Fr.) Quel 20, Folium Photiniae (Folium Photiniae serrulatae) 16, Radix Codonopsis Lanceolatae 14 and Folium Callicarpae Formosanae 3.
The preparation method of Chinese medicinal effective-part composition of the present invention is that add 16 times of water gagings, boil with high heat, change slow fire boiling into 2 hours, waste, to obtain final product by above-mentioned raw materials compositions according to proportioning combination drying.
Compared with prior art, the present invention has following beneficial effect:
Find through experiment, the Chinese medicinal effective-part composition made according to proportioning of the present invention has the effect of dispelling cold by warming the meridian, promoting blood circulation to remove obstruction in the collateral, regulating qi to disperse stagnation, clearing away heat-damp and promoting diuresis, removing toxic substances pain relieving, benefiting qi and nourishing blood, may be used for treating thromboangiitis obliterans, not easily recur after healing.
Detailed description of the invention
Explain the present invention further below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Fructus Perillae Frutescentis 26g, Pseudobulbus Bletillae (Rhizoma Bletillae) 21g, Coriolous Dersicolor (Fr.) Quel 20g, Folium Photiniae (Folium Photiniae serrulatae) 16g, Radix Codonopsis Lanceolatae 14g and Folium Callicarpae Formosanae 3g, add 16 times of water gagings after drying, after boiling with intense fire, then use slow fire decocting 120min, gained decoction is for subsequent use.
embodiment 2
Clinical observation Patients With Thromboangitis Obliterans 200.Patient is all diagnosed as thromboangiitis obliterans through clinical diagnosis.Embodiment 1 gained decoction is taken, 2 times on the 1st to patient, sooner or later bfore meals, continuous 30 days.
The patient census taking embodiment 1 gained decoction the results are shown in Table 1.Effective in table 1 comprises cures and effectively, wherein, cure and refer to that cardinal symptom disappears, wound heals completely, and suffering limb disturbance of blood circulation is alleviated or obviously improved, and resumes work in 1 year without recurring; Effectively refer to that clinical symptoms major part disappears or significantly alleviates, rest pain disappears, and skin temperature and color and luster are clearly better, wound healing or close to healing, blood circulation is slight obstacle, can work.Invalid refer to through treatment, clinical symptoms and sign all without improve, even increase the weight of.
Table 1
| Number of cases | Effective | Invalid | Obvious effective rate (%) |
| 200 | 187 | 13 | 93.5 |
Known by above-mentioned data, after decoction made by Chinese medicine of the present invention, can in 30 days the treatment thromboangiitis obliterans of highly significant.
embodiment 3
Use the decoction administration ICR mice that embodiment 1 is obtained, body weight 20 ~ 25g, male and female half and half, successive administration 60d.
Through prerun, the decoction toxicity that embodiment 1 obtains is very low, does not measure LD50, therefore carries out maximum dosage-feeding mensuration on the one to mice.Maximum dosage-feeding is 400ml/d, observes none example and be poisoned to death after 60 days, and all healthy survival, proves that the decoction that compositions of the present invention is made can not toxic side effect to human body thus.
Claims (2)
1. treat a Chinese medicine composition for thromboangiitis obliterans, it is characterized in that being made up of the following raw material according to mass fraction meter: Fructus Perillae Frutescentis 26, the Pseudobulbus Bletillae (Rhizoma Bletillae) 21, Coriolous Dersicolor (Fr.) Quel 20, Folium Photiniae (Folium Photiniae serrulatae) 16, Radix Codonopsis Lanceolatae 14 and Folium Callicarpae Formosanae 3.
2. the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 1, is characterized in that described Chinese medicine composition makes decoction.
3. treat the preparation method of the Chinese medicine composition of thromboangiitis obliterans described in claim 1 or 2, it is characterized in that add 16 times of water gagings, boil with high heat, change slow fire boiling into 2 hours, waste, to obtain final product by each crude drug according to proportioning combination drying.
4. the application of Chinese medicine composition described in claim 1 or 2, is characterized in that the medicine of described Chinese medicine composition for the preparation for the treatment of thromboangiitis obliterans.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310358200.XA CN103432397B (en) | 2013-08-17 | 2013-08-17 | Traditional Chinese medicine effective part composition for treating thromboangiitis obliterans |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310358200.XA CN103432397B (en) | 2013-08-17 | 2013-08-17 | Traditional Chinese medicine effective part composition for treating thromboangiitis obliterans |
Publications (2)
| Publication Number | Publication Date |
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| CN103432397A CN103432397A (en) | 2013-12-11 |
| CN103432397B true CN103432397B (en) | 2015-04-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310358200.XA Expired - Fee Related CN103432397B (en) | 2013-08-17 | 2013-08-17 | Traditional Chinese medicine effective part composition for treating thromboangiitis obliterans |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245715A (en) * | 1999-08-04 | 2000-03-01 | 章学常 | Yankang powder (paste) for relieving inflammation |
| CN1772229A (en) * | 2005-10-20 | 2006-05-17 | 叶明伟 | Chinese herbal medicine decoction for treating virulent heat-evil type thrombotic angeitis and its prepn |
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2013
- 2013-08-17 CN CN201310358200.XA patent/CN103432397B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245715A (en) * | 1999-08-04 | 2000-03-01 | 章学常 | Yankang powder (paste) for relieving inflammation |
| CN1772229A (en) * | 2005-10-20 | 2006-05-17 | 叶明伟 | Chinese herbal medicine decoction for treating virulent heat-evil type thrombotic angeitis and its prepn |
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| Publication number | Publication date |
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| CN103432397A (en) | 2013-12-11 |
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Owner name: ZHANG QUN Free format text: FORMER OWNER: GUANGZHOU YUNQIAO BIOTECHNOLOGY CO., LTD. Effective date: 20150226 |
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Effective date of registration: 20150226 Address after: The Eastern Development Zone of Guangzhou City, Guangdong province 510000 two Building Room 302 Xinyuan Street Chunhui Applicant after: Zhang Qun Address before: 510000, Guangzhou, Guangdong, Luogang District Province, No. 6, No. 601, Lai Lai Road Applicant before: Guangzhou Yunqiao Biological Technology Co., Ltd. |
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