CN103432220B - Traditional Chinese medicine preparation for treating aching and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating aching and preparation method thereof Download PDFInfo
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- CN103432220B CN103432220B CN201310312872.7A CN201310312872A CN103432220B CN 103432220 B CN103432220 B CN 103432220B CN 201310312872 A CN201310312872 A CN 201310312872A CN 103432220 B CN103432220 B CN 103432220B
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating aching. The traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: 10-20 parts of musk, 10-20 parts of saposhnikoviadivaricata, 10-20 parts of , 10-20 parts of angelica dahurica, 10-20 parts of asarum herb , 10-40 parts of caulis sinomenii, 10-40 parts ofnotopterygium root, 10-30 parts of radix angelicaepubescentis, 10-30 parts of boswelliacarteri, 10-30 parts of myrrh, 15-25 parts of radix aconitipreparata, 15-25 parts of salvia miltiorrhiza, 15-25 parts of epimeddium, 15-25 parts of copodii herb and 15-30 parts of speranskiatuberculata. The traditional Chinese medicine preparation is wide in raw material source, low in cost, substantial in treatment effect on aching with a total treatment effective ratio of 96%, substantial in ache alleviation effect, substantial in aching feeling reduction, short in ache alleviation time and fast in effectiveness. The preparation method of the traditional Chinese medicine preparation is simple and practicable, and the prepared preparation is convenient to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of Chinese medicine preparation being used for the treatment of pain and preparation method thereof
Background technology
Pain is that everyone is Zi the problem often run in the life process of death of being born, although at present for the existing multiple method that how to ease the pain, as anesthetics, antipyretic analgesic and rheumatism analgesic, but chronic pain is still felt simply helpless, many Therapeutic Method that the is traditional and modern times, effect is unsatisfactory.
Summary of the invention
Goal of the invention: the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of pain, present invention also offers the preparation method of said preparation, to realizing, alleviating pain effect is comparatively strong, onset time is fast, long action time.
Technical scheme: in order to realize foregoing invention object, the technical solution adopted in the present invention is:
Be used for the treatment of a Chinese medicine preparation for pain, be made up of the raw material of following parts by weight: 10 ~ 20 parts, Moschus, Radix Saposhnikoviae 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, Herba Asari 10 ~ 20 parts, Caulis Sinomenii 10 ~ 40 parts, Rhizoma Et Radix Notopterygii 10 ~ 40 parts, Radix Angelicae Pubescentis 10 ~ 30 parts, Olibanum 10 ~ 30 parts, Myrrha 10 ~ 30 parts, Radix Aconiti Preparata 15 ~ 25 parts, Radix Salviae Miltiorrhizae 15 ~ 25 parts, Herba Epimedii 15 ~ 30 parts, Herba Lycopodii 15 ~ 25 parts, Herba speranskiae tuberculatae 15 ~ 30 parts.
Preferably, be made up of the raw material of following parts by weight: 10 ~ 15 parts, Moschus, Radix Saposhnikoviae 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts, Herba Asari 10 ~ 15 parts, Caulis Sinomenii 20 ~ 30 parts, Rhizoma Et Radix Notopterygii 10 ~ 30 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Olibanum 10 ~ 20 parts, Myrrha 20 ~ 30 parts, Radix Aconiti Preparata 15 ~ 20 parts, Radix Salviae Miltiorrhizae 15 ~ 20 parts, Herba Epimedii 15 ~ 25 parts, Herba Lycopodii 15 ~ 20 parts, Herba speranskiae tuberculatae 20 ~ 30 parts.
Preferably, be made up of the raw material of following parts by weight: 20 parts, Moschus, Radix Saposhnikoviae 15 parts, the Radix Angelicae Dahuricae 15 parts, Herba Asari 15 parts, Caulis Sinomenii 20 parts, Rhizoma Et Radix Notopterygii 30 parts, Radix Angelicae Pubescentis 15 parts, Olibanum 20 parts, Myrrha 20 parts, Radix Aconiti Preparata 15 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Epimedii 15 parts, Herba Lycopodii 20 parts, Herba speranskiae tuberculatae 20 parts.
For the preparation of the method for the Chinese medicine preparation for the treatment of pain, the step of described method is: by Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae by quality proportioning prescription, with the ethanol 2000 ~ 5000ml of volumetric concentration 75%, filter after soaking 15d, again the prepared slices of Chinese crude drugs soaked are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, supernatant is extracted after precipitation, add Moschus, be adjusted to ethanol contend concentration 30 ~ 40%; By for subsequent use for the medicinal liquid dress spray bottle configured.
Beneficial effect: compared with prior art, remarkable advantage of the present invention is: raw material sources of the present invention are extensive, cheap; Chinese medicine preparation of the present invention treatment pain on evident in efficacy, total treated effect is 96%; Be very effective on alleviating pain, significantly reduces pain; Pain relieving time is short, rapid-action; Preparation method of the present invention is simple, and the preparation made is easy to use.
Detailed description of the invention
Below by specific embodiment, the present invention is further described; it should be pointed out that for the person of ordinary skill of the art, under the premise without departing from the principles of the invention; can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.
Embodiment 1
Get Moschus 10g, Radix Saposhnikoviae 10g, Radix Angelicae Dahuricae 10g, Herba Asari 10g, Caulis Sinomenii 10g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Olibanum 10g, Myrrha 10g, Radix Aconiti Preparata 15g, Radix Salviae Miltiorrhizae 15g, Herba Epimedii 15g, Herba Lycopodii 15g, Herba speranskiae tuberculatae 15g.By Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae by quality proportioning prescription, with the ethanol 2000ml of volumetric concentration 75%, filter after soaking 15d, again the prepared slices of Chinese crude drugs soaked are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to ethanol contend concentration 30%; By for subsequent use for the medicinal liquid dress spray bottle configured.
Embodiment 2
Get Moschus 20g, Radix Saposhnikoviae 20g, Radix Angelicae Dahuricae 20g, Herba Asari 20g, Caulis Sinomenii 40g, Rhizoma Et Radix Notopterygii 40g, Radix Angelicae Pubescentis 30g, Olibanum 30g, Myrrha 30g, Radix Aconiti Preparata 25g, Radix Salviae Miltiorrhizae 25g, Herba Epimedii 30g, Herba Lycopodii 25g, Herba speranskiae tuberculatae 30g.By Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae by quality proportioning prescription, with the ethanol 5000ml of volumetric concentration 75%, filter after soaking 15d, again the prepared slices of Chinese crude drugs soaked are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to ethanol contend concentration 40%; By for subsequent use for the medicinal liquid dress spray bottle configured.
Embodiment 3
Get Moschus 15g, Radix Saposhnikoviae 15g, Radix Angelicae Dahuricae 15g, Herba Asari 15g, Caulis Sinomenii 30g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 20g, Olibanum 20g, Myrrha 20g, Radix Aconiti Preparata 20g, Radix Salviae Miltiorrhizae 20g, Herba Epimedii 20g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 25g.By Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae by quality proportioning prescription, with the ethanol 3000ml of volumetric concentration 75%, filter after soaking 15d, again the prepared slices of Chinese crude drugs soaked are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to ethanol contend concentration 35%; By for subsequent use for the medicinal liquid dress spray bottle configured.
Embodiment 4
Get Moschus 20g, Radix Saposhnikoviae 15g, Radix Angelicae Dahuricae 15g, Herba Asari 15g, Caulis Sinomenii 20g, Rhizoma Et Radix Notopterygii 30g, Radix Angelicae Pubescentis 15g, Olibanum 20g, Myrrha 20g, Radix Aconiti Preparata 15g, Radix Salviae Miltiorrhizae 15g, Herba Epimedii 15g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g.By Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae by quality proportioning prescription, with the ethanol 4000ml of volumetric concentration 75%, filter after soaking 15d, again the prepared slices of Chinese crude drugs soaked are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to ethanol contend concentration 40%; By for subsequent use for the medicinal liquid dress spray bottle configured.
Embodiment 5
Stochastic choice 100 scapulohumeral periarthritis pain patients carry out clinical observation.Be divided into matched group and treatment group, often organize each 50 people.Two groups of ages, sex, course of disease comparable situation are in table 1.
Table 1
| Age/year | Men and women's ratio | The course of disease/year | |
| Matched group | 52.5±6.3 | 0.43 | 5.1±0.6 |
| Treatment group | 53.1±5.8 | 0.47 | 4.8±1.1 |
1, experimental technique
Treatment group application Chinese medicine percutaneous drug treatment, is specially: the medicinal liquid that embodiment 1 prepares directly is sprayed on diseased region, every day 4 times or several; The control group ibuprofen, each 2, every day 3 times, oral, damp-affection and pain relieving patch affected part, local, coordinates physical therapy.
2, observation index
1) fore-and-aft observing patient pain remission time is treated: to the time that pain relief, scoring change from treatment patients.
2) pain relief situation: pain degree judges with reference to pain scores method.1. 0 point: without any pain; 2. slight (1 point): indistinctly can feel and mild pain not cause worry; 3. moderate (2 points): often feel pain, but do not affect daily routines, can tolerate; 4. severe (3 points): often feel obvious pain, and affect daily routines and sleep, or be impatient at.
3, curative effect determinate standard
Cure: disappear through treating various pain symptom, function recovers normal completely or substantially, and pain scores is 0 point;
Take a turn for the better: symptom disappears substantially, shoulder joint function improve, pain scores reduce by 1 point and more than;
Invalid: through treatment more than 15d, symptom and pain still do not alleviate, and function is not improved.
4, experimental result
4.1 therapeutic effect
Therapeutic outcome is in table 2.Visible, the total effective rate for the treatment of group is far away higher than matched group, evident in efficacy.
Table 2 therapeutic effect compares
| Cure/example | Take a turn for the better/example | Invalid/example | Total effective rate/% |
| Matched group | 15 | 20 | 15 | 70 |
| Treatment group | 26 | 22 | 2 | 96 |
4.2 pain scores compare
Pain scores comparative result is in table 3, and visible treatment group scoring is remarkable in matched group, Be very effective on alleviating pain.
Table 3 is treated the two groups of pain scores in front and back and is compared
| Before treatment | After treatment | |
| Matched group | 2.3±0.6 | 1.4±0.7 |
| Treatment group | 2.3±0.9 | 0.8±0.2 |
4.3 pain relieving time
Matched group pain relieving time is 15.7 ± 3.8h, and treatment group pain relieving time is 4.2 ± 1.2h, and treatment group pain relieving time, significantly lower than matched group, illustrates rapid-action.
Claims (3)
1. be used for the treatment of a Chinese medicine preparation for pain, it is characterized in that being made up of the raw material of following parts by weight: 10 ~ 20 parts, Moschus, Radix Saposhnikoviae 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, Herba Asari 10 ~ 20 parts, Caulis Sinomenii 10 ~ 40 parts, Rhizoma Et Radix Notopterygii 10 ~ 40 parts, Radix Angelicae Pubescentis 10 ~ 30 parts, Olibanum 10 ~ 30 parts, Myrrha 10 ~ 30 parts, Radix Aconiti Preparata 15 ~ 25 parts, Radix Salviae Miltiorrhizae 15 ~ 25 parts, Herba Epimedii 15 ~ 30 parts, Herba Lycopodii 15 ~ 25 parts, Herba speranskiae tuberculatae 15 ~ 30 parts; The described Chinese medicine preparation prepared directly is sprayed on diseased region.
2. be used for the treatment of the Chinese medicine preparation of pain as claimed in claim 1, it is characterized in that being made up of the raw material of following parts by weight: 10 ~ 15 parts, Moschus, Radix Saposhnikoviae 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts, Herba Asari 10 ~ 15 parts, Caulis Sinomenii 20 ~ 30 parts, Rhizoma Et Radix Notopterygii 10 ~ 30 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Olibanum 10 ~ 20 parts, Myrrha 20 ~ 30 parts, Radix Aconiti Preparata 15 ~ 20 parts, Radix Salviae Miltiorrhizae 15 ~ 20 parts, Herba Epimedii 15 ~ 25 parts, Herba Lycopodii 15 ~ 20 parts, Herba speranskiae tuberculatae 20 ~ 30 parts.
3. be used for the treatment of the Chinese medicine preparation of pain as claimed in claim 1, it is characterized in that being made up of the raw material of following parts by weight: 20 parts, Moschus, Radix Saposhnikoviae 15 parts, the Radix Angelicae Dahuricae 15 parts, Herba Asari 15 parts, Caulis Sinomenii 20 parts, Rhizoma Et Radix Notopterygii 30 parts, Radix Angelicae Pubescentis 15 parts, Olibanum 20 parts, Myrrha 20 parts, Radix Aconiti Preparata 15 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Epimedii 15 parts, Herba Lycopodii 20 parts, Herba speranskiae tuberculatae 20 parts.
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| CN104352575A (en) * | 2014-10-21 | 2015-02-18 | 苏州经贸职业技术学院 | Medicated wine for promoting blood circulation and alleviating pain and preparation method thereof |
| CN109010697A (en) * | 2018-10-08 | 2018-12-18 | 江苏霍氏医药科技有限公司 | A kind of traditional Chinese medicine for outer use and preparation method thereof for treating cancer advanced stage pain |
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Effective date of registration: 20170306 Address after: 311100 Linping, Hangzhou, Yuhang District, East Lake North Road, No. 28, No. Patentee after: HANGZHOU RENDE PHARMACEUTICAL CO.,LTD. Address before: 212400 South of Jiangsu, Jiangsu, Jurong Province Economic Development Zone, the North Third Ring Road, Jiangsu Pharmaceutical Industry Co., Ltd., Patentee before: JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co.,Ltd. |
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Address after: No. 200, Donghu North Road, Linping District, Hangzhou, Zhejiang 311100 Patentee after: Hangzhou Rende Pharmaceutical Co.,Ltd. Address before: 311100 No.28 Donghu North Road, Linping, Yuhang District, Hangzhou City, Zhejiang Province Patentee before: HANGZHOU RENDE PHARMACEUTICAL CO.,LTD. |