CN103372211A - Antiviral compound preparation for fish - Google Patents
Antiviral compound preparation for fish Download PDFInfo
- Publication number
- CN103372211A CN103372211A CN 201210127462 CN201210127462A CN103372211A CN 103372211 A CN103372211 A CN 103372211A CN 201210127462 CN201210127462 CN 201210127462 CN 201210127462 A CN201210127462 A CN 201210127462A CN 103372211 A CN103372211 A CN 103372211A
- Authority
- CN
- China
- Prior art keywords
- anthelmintic
- compound preparation
- disease
- fish
- resistant compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides an antiviral compound preparation for fish. The compound preparation composition comprises microparticles containing macrolide anthelmintic, as well as two or more than two of bithionol, praziquantel, diflubenzuron, triflumuron, pyriproxyfen, sulfur powder, salicylanilide, organic phosphorus, benzimidazole, pyrethroid, triazine, tetramisole anthelmintic, sulfonamides, anticoccidial drugs and Chinese herbal medicine anthelmintic, wherein the microparticles containing macrolide anthelmintic are microspheres or microcapsules composed of biodegradable or non-biodegradable carrier materials and macrolide anthelmintic, and the content of the macrolide anthelmintic in the microparticles is 0.1-50%. The compound preparation provided by the invention can not only expand the insecticidal spectrum, but also effectively improve the anthelmintic activity and reduce toxicity so as to ensure safer use.
Description
Technical field
The present invention relates to the disease-resistant compound preparation of a kind of fish, belong to animal medicine technical field.
Background technology
Up to now, worldwide, be used for the medicine of the parasitic disease of control fish, also do not have good commodity to put goods on the market.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art part, provide a kind of fish disease-resistant compound preparation.
The disease-resistant compound preparation of fish of the present invention, said compound preparation compositions comprises the microsome that contains the Macrolide anthelmintic, also comprise bithionol (bithionole), praziquantel (prazaquanyel), diflubenzuron (diflubenzuron), triflumuron (triflumuron), pyriproxyfen (pyrioxyfen), Cosan, Salicylanilide, organic phosphates, benzimidazole, cinerins, triazines, tetramisole class anthelmintic, sulfa drugs, in anticoccidial class medicine and the Chinese herbal medicine class anthelmintic two or more, microsphere or microcapsule that the said microsome that contains the Macrolide anthelmintic is comprised of biodegradable or not biodegradable carrier material and Macrolide anthelmintic.
The content range of Macrolide anthelmintic is 0.001-10%(W/V in the said compound preparation), content range is the 0.05-50g/1000kg feedstuff in feedstuff.During the control fish parasite disease, dispensing every day (feeding) amount is 0.02-0.4mg/ per kilogram fish Biomass, connects and feeds 3-25 days, is used for killing the fish endoparasite and ectoparasite.Press per kilogram fish Biomass and calculate, dispensing every day (feeding) amount is respectively: bithionol 5-100mg, praziquantel 0.5-30mg, diflubenzuron 0.5-50mg, triflumuron 0.1-10mg, pyriproxyfen 0.3-10mg, Salicylanilide 0.5-50mg, organic phosphates 0.3-50mg, benzo miaow are frustrated class 0.5-30mg, cinerins 0.1-100mg, triazines 0.2-50mg, tetramisole class anthelmintic 0.5-15mg, sulfa drugs or anticoccidial class medicine 0.01-50mg.Compound preparation can be liquid, also can be solid.
Microsphere or microcapsule that the said microsome that contains the Macrolide anthelmintic is comprised of biodegradable or not biodegradable carrier material and Macrolide anthelmintic, the Macrolide anthelmintic content in the microsome is 0.1-50%.The microsome that contains the Macrolide anthelmintic can be suspended in the liquid solute, makes and mixes outstanding agent; Also can mix with other solid carrier particles granulation agent or powder; The microsome that contains the Macrolide anthelmintic still can form compound preparation with other medicines, the existence form of other medicines in preparation can be dissolved state (molecularity), also can be solid particle state (particle diameter is less than 50 μ m), also can be to be present in the compound preparation with microsphere or microcapsule state.The carrier material of preferred preparation microsphere or microcapsule comprises: gelatin, arabic gum, ethyl cellulose, polyvinylpyrrolidone, polyvinyl alcohol, polyamide, polyethylene, polrvinyl chloride, polypropylene, polylactic acid, methyl methacrylate, glycerol tristearate, hydrogenated vegetable oil, hydrogenated fish oil, polyvinyl butyral resin, Polyethylene Glycol.
Described Macrolide anthelmintic is selected from avilamycin (abamectin), ivermectin (ivermectin), Affirm (Merck Co.) (emamectin) or its benzoate, Ai Purui element bacterium (eprinomectin), doramectin (doramectin) or moxidectin (moxidectin).The fish of Affirm (Merck Co.) of the present invention (emamectin) or its benzoate can also add the feedstuff that is mixed that other drug forms compound preparation or contains multi-medicament with anthelmintic or the feedstuff that is mixed in the prescription or in the feedstuff.The content of Affirm (Merck Co.) or its benzoate is 0.001-10%(W/V in the compound preparation), the content range in feedstuff is the 0.05-50g/1000kg feedstuff.During with Affirm (Merck Co.) or its benzoate control fish parasite disease, dispensing every day (feeding) amount is 0.02-0.4mg/ per kilogram fish Biomass, connects and feeds 3-25 days, is used for killing the fish endoparasite and ectoparasite.
Described benzimidazole anthelmintic is selected from Albendazole (albendazole), rycobendazole (albendazole oxide), Phenbendasol (fenbendazole), oxfendazole (ocfendazole), Mebendazole (mebendazole), triclabendazole (triclabendazole), butylbenzene rattle away azoles, the third Anthelvet, Oxibendazole or thiabendazole.
Described organic phosphates anthelmintic comprises: acetyl methylamine phosphine (acephate), metrifonate (trichlorfon), phoxim (phoxim), phoxiom_methyl (phoxim-methyl), chlorpyrifos-methyl (chlorpyrifos-methyl), dichlorvos, fenthion, Ruelene, hello pine or naphthalene phosphorus.
Described sulfa drugs is selected from sulfadiazine (sulfadiazine), bacteresulf (sulfisoxazole), sulfathiazole, sulphaguanidine, trimethoprim or sulfanilamide quinoline and dislikes woods.
Described Salicylanilide anthelmintic is selected from closantel, iodo-ether salicylamine, niclosamide, oxyclozanide, chlorine sulphur willow aniline or clioxanide.
Described cinerins anthelmintic is selected from second hydrogen chrysanthemum ester or brofenxalerate.
Described anticoccidial class medicine is selected from sieve benzene Buddhist nun fourth, amprolium hydrochloride, ethopabate, dinitro deamination, chlorine pyrrole alcohol, nicarbazine, nitric acid dimethyl sulfide ammonia, benzene methoxy quinoline, fourth oxygen quinoline, last of the ten Heavenly stems oxygen quinoline, Chang Mount ketone, the spirit of killing, Salinomycin or monensin.
Described tetramisole class anthelmintic is selected from levamisole or tetramisole.
Described Chinese herbal medicine class anthelmintic is selected from the leachate of Rhizoma Osmundae, Herba Chenopodii, Caulis Perillae or bark of Melia azedarach L..
Can Macrolide anthelmintic and organic phosphates parasite killing and benzimidazole anthelmintic is composite among the present invention, make ternary compound preparation or pre-mixing agent.Pressing per kilogram fish Biomass calculates, dispensing (feeding) amount is: Macrolide anthelmintic 0.02-0.40mg, organophosphorus insecticides 0.5-50mg, benzimidazole anthelmintic 0.3-10mg, connect and fed 3-15 days, be used for killing parasitic nematode, trematodiasis, cestode and the arthropod class parasite of fish.
The granulation agent can be mixed the leachate of Chinese herbal medicine Rhizoma Osmundae, Herba Chenopodii, Caulis Perillae, bark of Melia azedarach L. and Macrolide anthelmintic, Semen Cucurbitae powder among the present invention.Calculate by per 100 kilograms of fish Biomass, the dispensing (feeding) amount be: Rhizoma Osmundae: 110-275g, Herba Chenopodii 34-86g, Caulis Perillae 21-50g, bark of Melia azedarach L. 34-86g(admix leachate in the granule respectively), Macrolide anthelmintic 2-40mg, Semen Cucurbitae powder 50-250g, connect and fed 3-15 days, be used for killing parasitic nematode, trematodiasis, trypanosomicide and the arthropod class parasite of fish.
Can be with benzimidazole anthelmintic and the composite granulation agent of organic phosphates anthelmintic among the present invention.Calculate by per 100 kilograms of fish Biomass, dispensing (feeding) amount is: benzimidazole 30-1000mg, organic phosphates 50-5000mg is for the vermin of killing fish.
Can be with Macrolide anthelmintic and the composite granulation agent of benzimidazole anthelmintic among the present invention.Press per kilogram fish Biomass and calculate, dispensing (feeding) amount is: Macrolide 0.02-0.40mg, benzimidazole anthelmintic 0.5-10mg connects and fed 3-15 days.
Preferred medicine is Affirm (Merck Co.) in the Macrocyclolactone lactone kind medicine, and it can form compound preparation or pre-mixing agent with one or more other anthelmintics or antibacterials.Compound preparation or pre-mixing agent can be solids, also can be liquid, and it can be taken for fish with the fish granulation agent that can feeding feedstuff be mixed.Press per kilogram fish Biomass and calculate, dispensing (feeding) amount is: 0.02-0.40mg; When using with other antinematodal agent, the suitable use amount of Affirm (Merck Co.) is 0.05-0.1mg, when composite with other antimicrobial drug, and pre-mixing agent has simultaneously antibiotic, anthelmintic double effects.It also can form compound preparation or pre-mixing agent with the cyclopropylamine piperazine, the final content of cyclopropylamine piperazine in feedstuff is the 0.1-150mg/kg feedstuff, press per kilogram fish Biomass and calculate, dispensing (feeding) amount is: Affirm (Merck Co.) 0.02-0.40mg, cyclopropylamine piperazine 10-50.It can also form compound preparation or pre-mixing agent with chrysanthemum ester type compound second cyanogen polyester and brofenxalerate, presses per kilogram fish Biomass and calculates, and dispensing (feeding) amount is: Affirm (Merck Co.) 0.02-0.40mg, second cyanogen polyester and brofenxalerate 0.1-100mg.
Preferred fish is acetylamino evericin with the best fragrance of parasiticide in the Macrocyclolactone lactone kind medicine, it can form compound preparation with one or more other anthelmintics or antibacterials or pre-mixing agent can be solid, also can be liquid, it can be taken for fish with the fish granulation agent that can feeding feedstuff be mixed.Press per kilogram fish Biomass and calculate, dispensing (feeding) amount is 0.005-0.40mg, and when driving nematicide when using with other, the suitable use amount of acetylamino evericin is 0.002-0.05mg.
The nematicide, trematodiasis, cestode and the arthropod parasite control that among the present invention Macrolide, benzimidazole and some Chinese herbal medicine are used for fish have good effect.Compound preparation of the present invention not only can enlarge insecticidal spectrum, can also effectively improve its anthelmintic activity and reduce toxicity, makes it to use safer.As Macrocyclolactone lactone kind medicine with have the Chinese herbal medicine that drives the nematicide activity when forming compound recipe, can reduce significantly the consumption of Macrolide anthelmintic, thereby make the Macrolide anthelmintic can more safely be applied to the control of fish parasite disease.
The specific embodiment
Embodiment 1
The disease-resistant compound preparation of the fish of present embodiment comprises according to percentage by weight: ivermectin 0.4%, oxfendazole 0.4%.
Preparation method: get 0.4kg ivermectin dissolve with ethanol, add afterwards and contain in the emulsion of oxfendazole 0.4kg, mixing mixes with the 10kg maize cob meal again, afterwards again with 90kg maize cob meal mixing and get final product.Get this compounding powder 1kg and the 999kg fish meal is mixed and made into granule, calculate by every 100kg fish Biomass, this granule 2.5kg that throws something and feeds every day connects and fed 18-22g days, can effectively prevent and treat fish parasitic nematode, cestode and arthropod class parasite, preventive effect can reach more than 90%.
Embodiment 2
The disease-resistant compound preparation of the fish of present embodiment comprises according to percentage by weight: Affirm (Merck Co.) 0.2%, praziquantel 5%, orthene 5%.
Preparation method: get Affirm (Merck Co.) 0.2kg, praziquantel 5 kg, a little dissolution with solvents of orthene 5 kg, afterwards with 100kg solid carrier (maize cob meal, calcium carbonate, powdered rice hulls, Semen Maydis powder, corn starch etc. all can) mixing and get final product.Get this compounding powder 1kg and the 999kg fish meal is mixed and made into granule, calculate by every 100kg fish Biomass, this granule 5kg that throws something and feeds every day connects and fed 21 days, can effectively prevent and treat fish parasitic nematode, trematodiasis, cestode and multiple parasite.
Embodiment 3
The disease-resistant compound preparation of the fish of present embodiment comprises according to percentage by weight: Affirm (Merck Co.) 1%, triflumuron 10%.
Preparation method: get Affirm (Merck Co.) 1kg and a small amount of dissolution with solvents of triflumuron 10kg, afterwards with 89kg corn starch mixing and get final product.Get this compounding powder 0.5kg and the 1000kg fish meal is mixed and made into granule, calculate by every 100kg fish Biomass, this granule 4kg that throws something and feeds every day, connect and fed 18 days, can effectively prevent and treat the epizoas such as fish endobiosis nematicide and argulus.
Embodiment 4
The disease-resistant compound preparation of the fish of present embodiment comprises according to percentage by weight: acetylamino evericin 0.2%, oxfendazole 2%, acetyl methylamine phosphine 5%.
Preparation method: get acetylamino evericin 0.2kg, oxfendazole 2kg, acetyl methylamine phosphine 5kg, with after a small amount of dissolution with solvents with 92.8kg carrier (maize cob meal or powdered rice hulls etc.) mixing, namely get this compound preparation.Get this compounding powder 1kg and 999kg feedstuff mixing, calculate by every 100kg fish Biomass, this granule 2-4kg that throws something and feeds every day, connect and fed 21 days, can effectively prevent and treat the arthropod class parasites such as nematicide, trematodiasis, cestode and Ichthyo-xenus tchangi Yu in the fish body.
Embodiment 5 contains the microsphere premix formulations preparation method of 0.2% Affirm (Merck Co.)
Affirm (Merck Co.) with ethyl cellulose/polyvinylpyrrolidone (1:3) embedding, is made microsphere, and its particle diameter is 50-100 μ m, and Affirm (Merck Co.) is 10% in the microsphere.Get this microsphere 2kg, mix with the 0.5kg soybean oil, after mixing thoroughly, with 98kg soybean cake powder (particle diameter is about 100 μ m) mix homogeneously, namely get the fish that contains 0.2% Affirm (Merck Co.) microsphere parasiticide pre-mixing agent, get this agent 1kg during use and mix with the 999kg fish meal and mix and make fine granule thoroughly, feeding volume is: this product 50g/ per kilogram fish Biomass, connect and fed 5-18 days, can be used for killing nematicide and external arthropod class parasite in the fish body.
Claims (10)
1. disease-resistant compound preparation of fish, it is characterized in that, said compound preparation compositions comprises the microsome that contains the Macrolide anthelmintic, also comprise bithionol, praziquantel, diflubenzuron, triflumuron, pyriproxyfen, Cosan, Salicylanilide, organic phosphates, benzimidazole, cinerins, triazines, tetramisole class anthelmintic, sulfa drugs, in anticoccidial class medicine and the Chinese herbal medicine class anthelmintic two or more, microsphere or microcapsule that the said microsome that contains the Macrolide anthelmintic is comprised of biodegradable or not biodegradable carrier material and Macrolide anthelmintic.
2. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described Macrolide anthelmintic is selected from avilamycin, ivermectin, Affirm (Merck Co.) or its benzoate, Ai Purui element bacterium, doramectin or moxidectin.
3. the disease-resistant compound preparation of fish according to claim 1, it is characterized in that described benzimidazole anthelmintic is selected from Albendazole, rycobendazole, Phenbendasol, oxfendazole, Mebendazole, triclabendazole, butylbenzene rattle away azoles, the third Anthelvet, Oxibendazole or thiabendazole.
4. the disease-resistant compound preparation of fish according to claim 1, it is characterized in that described organic phosphates anthelmintic comprises: acetyl methylamine phosphine, metrifonate, phoxim, phoxiom_methyl, chlorpyrifos-methyl, dichlorvos, fenthion, Ruelene, hello pine or naphthalene phosphorus.
5. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described sulfa drugs is selected from sulfadiazine, bacteresulf, sulfathiazole, sulphaguanidine, trimethoprim or sulfanilamide quinoline and dislikes woods.
6. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described Salicylanilide anthelmintic is selected from closantel, iodo-ether salicylamine, niclosamide, oxyclozanide, chlorine sulphur willow aniline or clioxanide.
7. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described cinerins anthelmintic is selected from second hydrogen chrysanthemum ester or brofenxalerate.
8. the disease-resistant compound preparation of fish according to claim 1, it is characterized in that described anticoccidial class medicine is selected from sieve benzene Buddhist nun fourth, amprolium hydrochloride, ethopabate, dinitro deamination, chlorine pyrrole alcohol, nicarbazine, nitric acid dimethyl sulfide ammonia, benzene methoxy quinoline, fourth oxygen quinoline, last of the ten Heavenly stems oxygen quinoline, Chang Mount ketone, the spirit of killing, Salinomycin or monensin.
9. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described tetramisole class anthelmintic is selected from levamisole or tetramisole.
10. the disease-resistant compound preparation of fish according to claim 1,, it is characterized in that described Chinese herbal medicine class anthelmintic is selected from the leachate of Rhizoma Osmundae, Herba Chenopodii, Caulis Perillae or bark of Melia azedarach L..
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210127462 CN103372211A (en) | 2012-04-27 | 2012-04-27 | Antiviral compound preparation for fish |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210127462 CN103372211A (en) | 2012-04-27 | 2012-04-27 | Antiviral compound preparation for fish |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103372211A true CN103372211A (en) | 2013-10-30 |
Family
ID=49458453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210127462 Pending CN103372211A (en) | 2012-04-27 | 2012-04-27 | Antiviral compound preparation for fish |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103372211A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198020A (en) * | 2017-05-08 | 2017-09-26 | 张银花 | A kind of disease-resistant getting fat high-yield feed of lobster |
| CN107929277A (en) * | 2017-10-25 | 2018-04-20 | 浙江省淡水水产研究所 | Application of the salinomycin in aquatic livestock vermin is killed |
| CN108309953A (en) * | 2018-03-30 | 2018-07-24 | 内蒙古拜克生物有限公司 | A kind of production method of salinomycin microcapsule granule |
| CN108498537A (en) * | 2018-06-25 | 2018-09-07 | 塔里木大学 | A kind of preparation and preparation method thereof for killing animal vermin |
| CN110381924A (en) * | 2017-09-06 | 2019-10-25 | 创技公司株式会社 | Particle and preparation method thereof comprising moxidectin |
| US10632137B2 (en) | 2017-08-30 | 2020-04-28 | Republic Of Korea (National Institute Of Fisheries Science) | Composition containing ivermectin for exterminating Clavinema mariae infection on Sebastes schlegeli |
-
2012
- 2012-04-27 CN CN 201210127462 patent/CN103372211A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198020A (en) * | 2017-05-08 | 2017-09-26 | 张银花 | A kind of disease-resistant getting fat high-yield feed of lobster |
| US10632137B2 (en) | 2017-08-30 | 2020-04-28 | Republic Of Korea (National Institute Of Fisheries Science) | Composition containing ivermectin for exterminating Clavinema mariae infection on Sebastes schlegeli |
| CN110381924A (en) * | 2017-09-06 | 2019-10-25 | 创技公司株式会社 | Particle and preparation method thereof comprising moxidectin |
| CN107929277A (en) * | 2017-10-25 | 2018-04-20 | 浙江省淡水水产研究所 | Application of the salinomycin in aquatic livestock vermin is killed |
| CN108309953A (en) * | 2018-03-30 | 2018-07-24 | 内蒙古拜克生物有限公司 | A kind of production method of salinomycin microcapsule granule |
| CN108309953B (en) * | 2018-03-30 | 2019-02-26 | 内蒙古拜克生物有限公司 | A kind of production method of salinomycin microcapsule granule |
| CN108498537A (en) * | 2018-06-25 | 2018-09-07 | 塔里木大学 | A kind of preparation and preparation method thereof for killing animal vermin |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103372211A (en) | Antiviral compound preparation for fish | |
| ES2199421T3 (en) | PROCEDURE FOR THE SEPARATION OF ACTIVE SUBSTANCES IN SOLID PHARMACEUTICAL PREPARATIONS. | |
| CN103444706A (en) | Dinotefuran granules and preparation method thereof | |
| WO2008062368A3 (en) | Micro-encapsulated capsicum, method for preparing the same and use thereof | |
| CN1386507A (en) | Compound antiparasitic medicine for fish or full-value feed containing antiparasitic medicine | |
| CN104054702B (en) | A kind of farm chemical carrier and application thereof | |
| CN105746564B (en) | A kind of Pesticidal combination containing imidacloprid and dimehypo and its preparation method and application | |
| CN102657211A (en) | Oil base preparation for preventing and treating diaspidiotus perniciosus comstock type pests | |
| CN101180969A (en) | Festhiazate avermectin granular formulation for killing nematode | |
| CN101766164A (en) | Monosultap imidacloprid liquid dispersibility effervescent tablet and preparation method thereof | |
| CN105475311A (en) | Spirotetramat containing granules, application and preparation method of spirotetramat containing granules | |
| CN103651424A (en) | Effervescent granule containing chlorantraniliprole and emamectin benzoate and preparation method thereof | |
| US9737386B2 (en) | Dosage projectile for remotely treating an animal | |
| CN105410015A (en) | Chlorpyrifos water-dispersible granule and preparation method of same | |
| CN100563443C (en) | Thiophene worm quinoline and phoxim insecticide composition | |
| CN102907447A (en) | Farm-oriented sterilization composition | |
| CN107693532A (en) | Compound anti-parasitic preparation and preparation method thereof | |
| CN103858926A (en) | Compound formula of trichlorphon and diazinon and preparation method of granules and fine granules | |
| CN103120168A (en) | Chlorfenapyr and cartap granular preparation | |
| CN103073349A (en) | Drug fertilizer granules for preventing rice damping-off and preparation method thereof | |
| CN103283740A (en) | Cyantraniliprole-containing pesticidal composition | |
| EP4298923A1 (en) | Method for preventing caking of xylitol and calcium aspartate mixture | |
| WO2009103901A3 (en) | Pharmaceutical composition containing an n‑phenylpyrazole derivative and glycofurol, use for the preparation of a topical veterinary medicament for combating fleas | |
| CN101380002A (en) | Insecticide and acaricide composition containing spirodiclofen | |
| CN103083345A (en) | Broad-spectrum anti-parasitic compound ivermectin tablet for pets |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131030 |