CN103356933A - Stomach-nourishing spleen-strengthening chewing tablets and preparation method thereof - Google Patents
Stomach-nourishing spleen-strengthening chewing tablets and preparation method thereof Download PDFInfo
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Abstract
The invention relates to stomach-nourishing spleen-strengthening chewing tablets and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The chewing tablets comprises the raw materials of, by weight: 6-9 parts of Mongolian milkvetch root, 5-8 parts of pilose asiabell root, 3-5 parts of ligusticum, 7-11 parts of common yam rhizome, 6-8 parts of dried longan, 8-12 parts of medlar, 7-9 parts of red date, 3-7 parts of dried tangerine peel, 8-12 parts of hawthorn fruit, 10-12 parts of stir-fried malt, 60-80 parts of microcrystalline cellulose, 10-20 parts of micro-powder silica gel, 2-10 parts of a hydroxymethyl cellulose, and 1-3 parts of a flavoring agent. The chewing tablets are prepared through three steps which are extraction, granulation, and tableting. The process provided by the invention is simple. The prepared chewing tablets have the advantages of rich nutrients, good taste, convenient application, and long effect. The tablets have the functions of stomach nourishing, spleen strengthening, qi invigorating, and digestion promoting.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of nourishing stomach and spleen chewable tablet and preparation method thereof.
Background technology
Fast development along with economy; the continuous quickening of rhythm of life; people's life stress also constantly increases; a lot of people's diet is irregular; be a meal of eating that does not have carefully, or be eating and drinking too much at one meal, the symptoms such as they diarrhoea often can occur, feel sick, vomiting, inappetence; do not have again the so-called organic disease of doctor trained in Western medicine to examination in hospital, then be referred to as with " subhealth state ".
On traditional Chinese medical science angle, gastropathy is given birth to, and then all kinds of diseases and ailments are from life, taste one disease, and then QI rising in reverse order, the stagnation of QI, then obstructed are then given birth to interior-heat, and the result organizes the normal circulation operation of QI and blood, and it is QI and blood in the consumer simultaneously also, causes QI and blood deficiency, easily tired, lassitude.
At present, the health product of nourishing stomach and spleen are not dissolved granulies on the market, are exactly tea, and when in use, they all need to open just and can take with blister, and are not only short in the effectiveness time, and in anhydrous situation, use extremely inconvenient; In addition, the effect of the nourishing stomach and spleen of nourishing stomach and spleen tea is subjected to the impact of brewing time larger.
Therefore, how overcoming the deficiencies in the prior art is problems that present technical field of Chinese medicines is needed solution badly.
Summary of the invention
The objective of the invention is provides a kind of nourishing stomach and spleen chewable tablet in order to solve the deficiencies in the prior art, and it has the effect that nourishing stomach and spleen, QI invigorating help digestion.
The technical solution used in the present invention is as follows:
A kind of nourishing stomach and spleen chewable tablet is characterized in that comprising the following raw material according to the parts by weight meter: 6 ~ 9 parts of the Radixs Astragali, 5 ~ 8 parts of Radix Codonopsis, 3 ~ 5 parts of Radix Angelicae Sinensis, 7 ~ 11 parts of Rhizoma Dioscoreaes, 6 ~ 8 parts of Arillus Longans, 8 ~ 12 parts of Fructus Lyciis, 7 ~ 9 parts of Fructus Jujubaes, 3 ~ 7 parts of Pericarpium Citri Reticulataes, 8 ~ 12 parts of Fructus Crataegis, 10 ~ 12 parts of Fructus Hordei Germinatus (parched)s, 60 ~ 80 parts of microcrystalline Cellulose, 10 ~ 20 parts of micropowder silica gels, 2 ~ 10 parts of hydroxy methocel, 1 ~ 3 part of correctives.
Further preferably be that described correctives is one or more in aspartame, acesulfame potassium and the stevioside.
The present invention also provides a kind of preparation method of nourishing stomach and spleen chewable tablet, it is characterized in that may further comprise the steps:
The first step is extracted: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 150 ~ 200 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, thickening temperature is 40 ~ 50 ℃, obtains Chinese medicinal ointment;
Second step is granulated: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel and the correctives mix homogeneously that step 1 obtains, and freezing and pulverizing, the temperature of freezing and pulverizing is-25 ~-10 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 12 ~ 16 mesh sieves, and last tabletting namely obtains product of the present invention.
The mechanism of action of product of the present invention:
The Radix Astragali that the present invention selects: invigorating the spleen and regulating the stomach, invigorating the spleen and replenishing QI; Radix Codonopsis: invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting can anti-gastric mucosa injury; Radix Angelicae Sinensis: inrigorating qi and promoting blood circulation, regulate body's immunity; Rhizoma Dioscoreae: invigorating the spleen and replenishing QI, quench one's thirst promote the production of body fluid, beneficial heart and tranquilizing mind, strengthen body immunity; Arillus Longan: appetite promoting and the spleen strengthening, enriching yin and nourishing kidney, invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind; Fructus Lycii: QI invigorating stomach invigorating, allaying tiredness; Fructus Jujubae: invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid, close the spleen stomach invigorating; Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Fructus Crataegi: appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm; Fructus Hordei Germinatus (parched): promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite.
The present invention is by composite above-mentioned several Chinese medicines that are of high nutritive value, produce the nourishing stomach and spleen chewable tablet, nourishing stomach and spleen, QI invigorating help digestion effectively, simultaneously, the specific surface area of the micropowder silica gel of selecting among the present invention is large, adsorption is strong, and good coating function is arranged, and can adsorb and cover the abnormal smells from the patient of product; Though water insoluble, it has good hydrophilic, the swelling action behind its chance water is conducive to the disintegrate of chewable tablet, and the active ingredient of Chinese herbs of absorption parcel can effectively spread out, and more is conducive to active component and plays a role.
The present invention compared with prior art, its beneficial effect is:(1) product of the present invention is nutritious, and mouthfeel is better, has the effect that nourishing stomach and spleen, QI invigorating help digestion; (2) product of the present invention is easy to use, and the effectiveness time is long; (3) product preparation method of the present invention is simple, is easy to apply.
Specific embodiment
A kind of nourishing stomach and spleen chewable tablet comprises the following raw material according to the parts by weight meter: 6 ~ 9 parts of the Radixs Astragali, 5 ~ 8 parts of Radix Codonopsis, 3 ~ 5 parts of Radix Angelicae Sinensis, 7 ~ 11 parts of Rhizoma Dioscoreaes, 6 ~ 8 parts of Arillus Longans, 8 ~ 12 parts of Fructus Lyciis, 7 ~ 9 parts of Fructus Jujubaes, 3 ~ 7 parts of Pericarpium Citri Reticulataes, 8 ~ 12 parts of Fructus Crataegis, 10 ~ 12 parts of Fructus Hordei Germinatus (parched)s, 60 ~ 80 parts of microcrystalline Cellulose, 10 ~ 20 parts of micropowder silica gels, 2 ~ 10 parts of hydroxy methocel, 1 ~ 3 part of correctives.Described correctives is one or more in aspartame, acesulfame potassium and the stevioside.
The preparation method of nourishing stomach and spleen chewable tablet of the present invention is characterized in that may further comprise the steps:
The first step is extracted: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 150 ~ 200 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, thickening temperature is 40 ~ 50 ℃, obtains Chinese medicinal ointment;
Second step is granulated: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel and the correctives mix homogeneously that step 1 obtains, and freezing and pulverizing, the temperature of freezing and pulverizing is-25 ~-10 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 12 ~ 16 mesh sieves, and last tabletting namely obtains product of the present invention.
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1
A kind of nourishing stomach and spleen chewable tablet comprises the following raw material according to the parts by weight meter: 6 parts of the Radixs Astragali, 5 parts of Radix Codonopsis, 3 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Dioscoreaes, 6 parts of Arillus Longans, 8 parts of Fructus Lyciis, 7 ~ 9 parts of Fructus Jujubaes, 3 parts of Pericarpium Citri Reticulataes, 8 parts of Fructus Crataegis, 10 parts of Fructus Hordei Germinatus (parched)s, 60 parts of microcrystalline Cellulose, 10 parts of micropowder silica gels, 2 parts of hydroxy methocel, 1 part of aspartame, 0.5 part of acesulfame potassium, 1.5 parts of steviosides.
The preparation method of the nourishing stomach and spleen chewable tablet of present embodiment may further comprise the steps:
The first step is extracted: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 200 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, thickening temperature is 40 ℃, obtains Chinese medicinal ointment;
Second step is granulated: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel, aspartame, acesulfame potassium and the stevioside mix homogeneously that step 1 obtains, and freezing and pulverizing, the temperature of freezing and pulverizing is-25 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 12 mesh sieves, and at last in room temperature, humidity is 45% condition lower sheeting, namely obtains the embodiment product.
Embodiment 2
A kind of nourishing stomach and spleen chewable tablet comprises the following raw material according to the parts by weight meter: 9 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 5 parts of Radix Angelicae Sinensis, 11 parts of Rhizoma Dioscoreaes, 8 parts of Arillus Longans, 12 parts of Fructus Lyciis, 9 parts of Fructus Jujubaes, 7 parts of Pericarpium Citri Reticulataes, 12 parts of Fructus Crataegis, 12 parts of Fructus Hordei Germinatus (parched)s, 80 parts of microcrystalline Cellulose, 20 parts of micropowder silica gels, 10 parts of hydroxy methocel, 1 part of stevioside.
The preparation method of the nourishing stomach and spleen chewable tablet of present embodiment may further comprise the steps:
The first step is extracted: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 200 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, thickening temperature is 50 ℃, obtains Chinese medicinal ointment;
Second step is granulated: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel and the stevioside mix homogeneously that step 1 obtains, and freezing and pulverizing, the temperature of freezing and pulverizing is-10 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 16 mesh sieves, and at last in room temperature, humidity is 30% condition lower sheeting, namely obtains the embodiment product.
Embodiment 3
A kind of nourishing stomach and spleen chewable tablet comprises the following raw material according to the parts by weight meter: 7 parts of the Radixs Astragali, 6 parts of Radix Codonopsis, 4 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Dioscoreaes, 7 parts of Arillus Longans, 11 parts of Fructus Lyciis, 7 ~ 9 parts of Fructus Jujubaes, 5 parts of Pericarpium Citri Reticulataes, 9 parts of Fructus Crataegis, 11 parts of Fructus Hordei Germinatus (parched)s, 70 parts of microcrystalline Cellulose, 15 parts of micropowder silica gels, 8 parts of hydroxy methocel, 0.8 part of aspartame, 1 part of acesulfame potassium.
The preparation method of the nourishing stomach and spleen chewable tablet of present embodiment may further comprise the steps:
The first step is extracted: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 180 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, thickening temperature is 45 ℃, obtains Chinese medicinal ointment;
Second step is granulated: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel, aspartame and the acesulfame potassium mix homogeneously that step 1 obtains, and freezing and pulverizing, the temperature of freezing and pulverizing is-18 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 14 mesh sieves, and at last in room temperature, humidity is 36% condition lower sheeting, namely obtains the embodiment product.
The quality index of product of the present invention:
1, organoleptic indicator
This product is tablet, and it is sweet to distinguish the flavor of.
2, physical and chemical index
Label hardness is 4.90 ± 0.01kg/cm3;
Disintegration time≤30min;
3, microbiological indicator
Bacterial population≤10/g
Yeast and mold number≤10/g
Pathogenic bacterium must not detect.
Clinical application cases:
Case 1: Lee so-and-so, woman, 45 years old.
The figure is little fat, puffiness of face, and the shoulder back of the body and neck are heavy, feel dizzy, poor sleeping quality, flatulence, uncomfortable in chest, nervous, weak.Take present embodiment 3 products after 15 days, puffiness of face, the shoulder back of the body and neck are heavy, feel dizzy, poor sleeping quality, flatulence, uncomfortable in chest, nervous, the symptom such as weak obviously alleviates, and continues to take, and after 2 months, above-mentioned symptom disappears substantially.After cutting out, have no recurrence.
Case 2: Zhang, man, 56 years old.
Abdominal distention, appetite is uncomfortable, has no appetite for food fatiguability, easy catching a cold.Take present embodiment 3 products after 15 days, abdominal distention, the symptoms such as appetite discomfort disappear substantially, continue to take, and after 2 months, health takes a turn for the better, and is energetic.
Claims (3)
1. a nourishing stomach and spleen chewable tablet is characterized in that comprising the following raw material according to the parts by weight meter: 6 ~ 9 parts of the Radixs Astragali, 5 ~ 8 parts of Radix Codonopsis, 3 ~ 5 parts of Radix Angelicae Sinensis, 7 ~ 11 parts of Rhizoma Dioscoreaes, 6 ~ 8 parts of Arillus Longans, 8 ~ 12 parts of Fructus Lyciis, 7 ~ 9 parts of Fructus Jujubaes, 3 ~ 7 parts of Pericarpium Citri Reticulataes, 8 ~ 12 parts of Fructus Crataegis, 10 ~ 12 parts of Fructus Hordei Germinatus (parched)s, 60 ~ 80 parts of microcrystalline Cellulose, 10 ~ 20 parts of micropowder silica gels, 2 ~ 10 parts of hydroxy methocel, 1 ~ 3 part of correctives.
2. nourishing stomach and spleen chewable tablet according to claim 1 is characterized in that described correctives is one or more in aspartame, acesulfame potassium and the stevioside.
3. such as the preparation method of right 1 described nourishing stomach and spleen chewable tablet, it is characterized in that may further comprise the steps:
The first step, extract: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Arillus Longan, Fructus Lycii, Fructus Jujubae, Pericarpium Citri Reticulatae, Fructus Crataegi and Fructus Hordei Germinatus (parched) are crushed to 150 ~ 200 orders in the lump, carry out the percolation extraction with deionized water as leaching solvent, extracting solution is left standstill, get the supernatant, then vacuum concentration is to paste, and thickening temperature is 40 ~ 50 ℃, obtains Chinese medicinal ointment;
Second step, granulate: with Chinese medicinal ointment, microcrystalline Cellulose, micropowder silica gel and the correctives mix homogeneously that step 1 obtains, freezing and pulverizing, the temperature of freezing and pulverizing is-25 ~-10 ℃, wet granulation obtains Chinese medicinal granule;
The 3rd step, tabletting: the Chinese medicinal granule vacuum drying with step 2 obtains, then add hydroxy methocel, mix homogeneously is crossed 12 ~ 16 mesh sieves, and last tabletting namely obtains product of the present invention.
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