CN103341099A - Traditional Chinese medicine essence for preventing and treating psoriasis, and extraction method thereof - Google Patents
Traditional Chinese medicine essence for preventing and treating psoriasis, and extraction method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine essence for preventing and treating psoriasis, and an extraction method thereof. The traditional Chinese medicine essence is extracted from a mixture of skullcap, cortex dictamni, rhizoma smilacis glabrae, fructus kochiae and radix rehmanniae with the same content or with nearly equal content. The extraction method of the essence comprises the steps of: weighing the materials according to the proportion; washing the raw materials and drying the materials for later use; mixing and crushing the raw traditional Chinese medicine materials for later use; adding water to form crushed paste; heating the crushed paste to 100 DEG C and decocting the crushed paste for 50 minutes, then filtering the crushed paste to obtain a traditional Chinese medicine liquid; cooling the traditional Chinese medicine liquid, adding an additive and stirring the mixture for a certain time; using edible acetic acid to regulate the pH to 4.0; stewing the traditional Chinese medicine liquid for one day; drying the stewed liquid to obtain a dry powdery traditional Chinese medicine essence for preventing and treating psoriasis. By the application in a short treatment course, the traditional Chinese medicine essence disclosed by the invention can remit, stabilize and remove pruritus symptom of the psoriasis, also restrains relapse of the disease for a long time, and has a remarkable curative effect. Besides, the extraction method of the traditional Chinese medicine essence disclosed by the invention has simple steps and high extraction rate, and is convenient to implement and suitable for large-scale batch production.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine and method for making thereof, relate in particular to a kind of anti-antipsoriatic Chinese medicine essence and extraction process thereof.
Background technology
As everyone knows, psoriasis is a kind of pertinacious disease, its medical science called after psoriasis.The saying that " interior not controlling breathed heavily, and do not control tinea outward " medically also arranged.Psoriasis is the focus of domestic and international medical circle research always.Though up to now, the definite pathogenesis of psoriasis is unclear as yet, but has the comparison tangible proof to show that psoriatic morbidity is all multifactor relevant with heredity, nervous function imbalance, viral streptococcal infection, endocrine regulation, dysimmunity, wound, diet environment etc.
Usually, the western medical treatment psoriasis adopts hormone medicine, ultraviolet illumination, antitumor metabolism class medicine, its untoward reaction comprises that " liver function injury, bone marrow depression, damage renal tubules, situation such as hematuria occurs, compare with doctor trained in Western medicine, the traditional Chinese medical science has mainly laid particular stress on the whole and macroscopical of people.The traditional Chinese medical science thinks that the psoriatic cause of disease is: heat in blood, blood are dry, blood stasis, blood oozing from the body openings or subcuta neous tissue etc., and it cures mainly principle and is: heat clearing and damp drying, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling etc., i.e. outer sick treatment by oral administration of medicines.
Because psoriasis is a kind of chronic disease, and it is wider to involve the crowd, it is very big to the life influence that the patient causes.Pruritus, squama and visible speckle are puzzlement patient's subject matter.In default of the method for long-term radical cure, though current Therapeutic Method is effective, but still can not be satisfactory.Develop special, safe and effective long-term treatment method and be still a challenge.
Summary of the invention
In view of the demand that above-mentioned prior art exists, the objective of the invention is to propose a kind of anti-antipsoriatic Chinese medicine essence, and propose the higher Chinese medicine essence extraction process of a kind of effective ingredient extraction.
One of above-mentioned purpose of the present invention is prevented antipsoriatic Chinese medicine essence, its technical scheme that is achieved is: described Chinese medicine essence extracts the mixture from Radix Scutellariae, Cortex Dictamni, Rhizoma Smilacis Glabrae, the Fructus Kochiae, the Radix Rehmanniae, and identical or each constituent content of each constituent content of described mixture differs each other less than 10% by weight.
Further, described mixture component by weight is: 16 parts of Radix Scutellariae, 21 parts of Cortex Dictamni, 23 parts of Rhizoma Smilacis Glabraes, 17 parts of the Fructus Kochiae, 23 parts in the Radix Rehmanniae.
Further, described mixture component by weight is: 20 parts of Radix Scutellariae, 20 parts of Cortex Dictamni, 20 parts of Rhizoma Smilacis Glabraes, 20 parts of the Fructus Kochiae, 20 parts in the Radix Rehmanniae.
Further, described mixture component by weight is: 22 parts of Radix Scutellariae, 15 parts of Cortex Dictamni, 21 parts of Rhizoma Smilacis Glabraes, 24 parts of the Fructus Kochiae, 18 parts in the Radix Rehmanniae.
The extraction process of two anti-antipsoriatic Chinese medicine essences of above-mentioned purpose of the present invention, its technical scheme that is achieved comprises operating procedure: I, by five kinds of raw material of Chinese medicine of mass ratio weighing, identical or each constituent content of each constituent content differs each other less than 10%, carry out routine and clean in stainless steel tank, taking-up is dried standby; II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry; IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, the protease, 0.3% cellulase and 0.2% the diastase that add raw material of Chinese medicine gross weight 0.3% again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature to carry out dry 5-8 hour for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 5-7% of three kinds of raw material of Chinese medicine gross weights.
The technical scheme of Chinese medicine essence of the present invention and extraction process thereof, its outstanding effect is: this Chinese medicine essence can be realized alleviation, stable, the transference cure of psoriasis pruritus by the use of the shorter course for the treatment of and suppress the long-term recurrence of disease, have outstanding curative effect effect.In addition, extraction process step of the present invention is simple, and it is convenient to implement, and extraction is higher, and being suitable in batches, scale produces.
The specific embodiment
Because at present psoriasis (psoriasis) is difficult to effective treatment, the concentrated research of this case creator Chinese medicine medical knowledge can effectively be prevented antipsoriatic Chinese medicinal herbs material, test through exploring, and finds technical solution preferably finally.
After deliberation, the present invention proposes a kind of anti-antipsoriatic Chinese medicine essence, it extracts the mixture from Radix Scutellariae, Cortex Dictamni, Rhizoma Smilacis Glabrae, the Fructus Kochiae, the Radix Rehmanniae, and identical or each constituent content of each constituent content of described mixture differs each other less than 10% by weight.
From pharmacology: Radix Scutellariae has heat-clearing toxin-expelling functions, and has the effect of anti-inflammatory, antiallergic, antiallergic action.Be modern common-use words anaphylaxis dermatosis, urticaria, psoriatic medicine commonly used.
Cortex Dictamni has heat clearing and damp drying, the effect of the detoxifcation of dispeling the wind.Cure mainly damp and hot skin infection, scall mange, skin pruritus, wind heat poison.Can treat erythra, urticaria, dermatitis etc.Cortex Dictamni contains dictamine, and ultraviolet is played a role in vivo, and has the effect of antiallergic action.
Rhizoma Smilacis Glabrae has the effect of heat-clearing and toxic substances removing, eliminating dampness and dredging channels, can cure mainly damp and hot sore.And Rhizoma Smilacis Glabrae is to act on stronger immunosuppressant simply, and is clinical in lupus erythematosus, Behcet disease, psoriasis.
The Fructus Kochiae has perverse clearly damp and hot effect, cures mainly damp invasion of lower energizer, skin eczema.Clinical in allergic dermatitis, psoriasis and tinea manus and pedis etc.
The effect that have the Radix Rehmanniae YIN nourishing and the production of body fluid promoting, removing heat from blood nourish blood, main treatment immunity back red tongue, yin asthenia generating intrinsic heat clinically are as lupus erythematosus, anaphylactoid purpura, allergic dermatitis and psoriasis.
Above Chinese medicine of the five flavours can effectively suppress the dermatosis based on psoriasis.And by the Chinese medicine essence that extraction process with low cost obtains, can produce the immunity of specificity and persistence.
Embodiment one: a kind of extraction process of anti-antipsoriatic Chinese medicine essence, it comprises following operating procedure.
I, by five kinds of each 10kg of raw material of Chinese medicine of mass ratio weighing, in stainless steel tank, carry out routine and clean, take out dry standby;
II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry;
IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add the protease of 0.15kg, the cellulase of 0.15kg and the diastase of 0.1kg again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 5 hours for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 3.5kg of three kinds of raw material of Chinese medicine gross weights.
Embodiment two: a kind of extraction process of anti-antipsoriatic Chinese medicine essence, it comprises following operating procedure.
I, by five kinds of raw material of Chinese medicine of mass ratio weighing: 16 parts of Radix Scutellariae, 21 parts of Cortex Dictamni, 23 parts of Rhizoma Smilacis Glabraes, 17 parts of the Fructus Kochiae, 23 parts in the Radix Rehmanniae, in stainless steel tank, carry out routine and clean, take out dry standby;
II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry;
IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add the protease of 0.15kg, the cellulase of 0.15kg and the diastase of 0.1kg again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 6 hours for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 3.3kg of three kinds of raw material of Chinese medicine gross weights.
Embodiment three: a kind of extraction process of anti-antipsoriatic Chinese medicine essence, it comprises following operating procedure.
I, by five kinds of raw material of Chinese medicine of mass ratio weighing: 20 parts of Radix Scutellariae, 20 parts of Cortex Dictamni, 20 parts of Rhizoma Smilacis Glabraes, 20 parts of the Fructus Kochiae, 20 parts in the Radix Rehmanniae, in stainless steel tank, carry out routine and clean, take out dry standby;
II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry;
IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add the protease of 0.15kg, the cellulase of 0.15kg and the diastase of 0.1kg again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 6.5 hours for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 3.2kg of three kinds of raw material of Chinese medicine gross weights.
Embodiment four: a kind of extraction process of anti-antipsoriatic Chinese medicine essence, it comprises following operating procedure.
I, by five kinds of raw material of Chinese medicine of mass ratio weighing: 22 parts of Radix Scutellariae, 15 parts of Cortex Dictamni, 21 parts of Rhizoma Smilacis Glabraes, 24 parts of the Fructus Kochiae, 18 parts in the Radix Rehmanniae, in stainless steel tank, carry out routine and clean, take out dry standby;
II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry;
IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add the protease of 0.15kg, the cellulase of 0.15kg and the diastase of 0.1kg again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 7 hours for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 3kg of three kinds of raw material of Chinese medicine gross weights.
The embodiment of the invention is intended to be convenient to understand innovation essence of the present invention; but do not limit protection scope of the present invention; all simple modification or equivalence are replaced, or utilize this finished product powder processing and fabricating capsule, pill, injection etc., all should be contained among the scope of the present invention.
Medical record is introduced: the anti-antipsoriatic Chinese medicine extraction element of the present invention is through development for many years, and the input clinical trial is evident in efficacy.
Case 1., patient Zhao Fusheng, man 74 years old, certain College Teachers suffers from psoriasis vulgaris 10 years and whole body and controls for a long time and do not heal, summer is agonizing especially.Through taking this by the Chinese medicine essence of five Chinese medicine mixed extraction gained, three times on the one, about each 2 grams, only a month whole body is very itched and is just disappeared, enters the regulator in second month, and scurf reduces gradually, attenuation, whole skin is level and smooth as ordinary person after four months, and the patient is very joyful.
Case 2., patient Zhao Bin, man 36 years old, certain co-director suffers from psoriasis vulgaris 6 years and controls for a long time and do not heal, summer, the state of an illness was also very serious, whole body pruritus, painful hard to bear.Through taking this by the Chinese medicine essence of five Chinese medicine mixed extraction gained, 7-8g divided and took for three times every day.Its curative effect also is antipruritic in one month, and two or three months does not recur after 10 years essences that begin to take traditional Chinese medicine are cured drug withdrawal so far with regard to stable disease, improvement again.
This shows, development and the application of the anti-antipsoriatic Chinese medicine essence of the present invention and extraction process thereof, compare to existing other Chinese medicine semi-finished product or Chinese medicine eating method, this Chinese medicine essence can be realized alleviation, stable, the transference cure of psoriasis pruritus by the use of the shorter course for the treatment of and suppress the long-term recurrence of disease, have outstanding curative effect effect.In addition, extraction process step of the present invention is simple, and it is convenient to implement, and extraction is higher, and being suitable in batches, scale produces.
Claims (5)
1. prevent antipsoriatic Chinese medicine essence for one kind, it is characterized in that: described Chinese medicine essence extracts the mixture from Radix Scutellariae, Cortex Dictamni, Rhizoma Smilacis Glabrae, the Fructus Kochiae, the Radix Rehmanniae, and identical or each constituent content of each constituent content of described mixture differs each other less than 10% by weight.
2. according to the described anti-antipsoriatic Chinese medicine essence of claim 1, it is characterized in that: described mixture component by weight is: 16 parts of Radix Scutellariae, 21 parts of Cortex Dictamni, 23 parts of Rhizoma Smilacis Glabraes, 17 parts of the Fructus Kochiae, 23 parts in the Radix Rehmanniae.
3. according to the described anti-antipsoriatic Chinese medicine essence of claim 1, it is characterized in that: described mixture component by weight is: 20 parts of Radix Scutellariae, 20 parts of Cortex Dictamni, 20 parts of Rhizoma Smilacis Glabraes, 20 parts of the Fructus Kochiae, 20 parts in the Radix Rehmanniae.
4. according to the described anti-antipsoriatic Chinese medicine essence of claim 1, it is characterized in that: described mixture component by weight is: 22 parts of Radix Scutellariae, 15 parts of Cortex Dictamni, 21 parts of Rhizoma Smilacis Glabraes, 24 parts of the Fructus Kochiae, 18 parts in the Radix Rehmanniae.
5. the extraction process of an anti-antipsoriatic Chinese medicine essence, its feature comprises operating procedure:
I, by five kinds of raw material of Chinese medicine of mass ratio weighing, identical or each constituent content of each constituent content differs each other less than 10%, carries out routine and clean in stainless steel tank, take out dry standby;
II, standby raw material of Chinese medicine mixed pulverize, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 50 minutes, and put into pressure filter again and filter and obtain the herb liquid slurry;
IV, in aseptic dust free room, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, the protease, 0.3% cellulase and 0.2% the diastase that add raw material of Chinese medicine gross weight 0.3% again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature to carry out dry 5-8 hour for 50 ℃, obtain the anti-antipsoriatic Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is the 6-7% of three kinds of raw material of Chinese medicine gross weights.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1739753A (en) * | 2004-08-27 | 2006-03-01 | 闫晓东 | Psoriasis treating Chinese medicine prepn and its pren process |
| CN1939498A (en) * | 2006-10-19 | 2007-04-04 | 王信锁 | Chinese-medicinal preparation for treating psoriasis |
| CN101637585A (en) * | 2009-08-20 | 2010-02-03 | 卢速江 | Chinese herbal preparation for treating posirasis and preparation method thereof |
| CN102114230A (en) * | 2011-02-21 | 2011-07-06 | 刘绍居 | Medicament for treating psoriasis |
| CN102362951A (en) * | 2011-10-25 | 2012-02-29 | 李安明 | Traditional Chinese medicine for treating psoriasis |
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2013
- 2013-07-10 CN CN2013102880618A patent/CN103341099A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1739753A (en) * | 2004-08-27 | 2006-03-01 | 闫晓东 | Psoriasis treating Chinese medicine prepn and its pren process |
| CN1939498A (en) * | 2006-10-19 | 2007-04-04 | 王信锁 | Chinese-medicinal preparation for treating psoriasis |
| CN101637585A (en) * | 2009-08-20 | 2010-02-03 | 卢速江 | Chinese herbal preparation for treating posirasis and preparation method thereof |
| CN102114230A (en) * | 2011-02-21 | 2011-07-06 | 刘绍居 | Medicament for treating psoriasis |
| CN102362951A (en) * | 2011-10-25 | 2012-02-29 | 李安明 | Traditional Chinese medicine for treating psoriasis |
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Application publication date: 20131009 |