CN103330059B - Health care composition for livestock as well as preparation method and application thereof - Google Patents
Health care composition for livestock as well as preparation method and application thereof Download PDFInfo
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- CN103330059B CN103330059B CN201310249913.2A CN201310249913A CN103330059B CN 103330059 B CN103330059 B CN 103330059B CN 201310249913 A CN201310249913 A CN 201310249913A CN 103330059 B CN103330059 B CN 103330059B
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Abstract
The invention provides a health care composition for livestock as well as a preparation method and an application thereof. The health care composition mainly comprises the components bacillus subtilis, bacillus licheniformis, mannan oligosaccharide, vitamin A, vitamin D3, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin C, sodium chloride, astragalus polysaccharide and the like; the components are synergistic and promoted each other and play synergistic interaction in the aspects of promoting animal growth and preventing and treating diseases, and economic value of the culture industry is obviously increased.
Description
Technical field
The present invention relates to a kind of animal health composition and method of making the same and purposes.
Background technology
From the fifties in last century, in animal diets, add antibiotic and significantly promoted animal production, and the development of intensive animal husbandry has been made to major contribution.Yet As time goes on, in feed, add antibiotic harm and day by day manifest, and be subject to social extensive concern.2004, WTO, FAO (Food and Agriculture Organization of the United Nation) (FAO) and OIE (OIE) combined and hold symposium, and the antibiotic use of inhuman use and antibiotic drug resistance problem have been discussed.European Union completely forbids and in animal and fowl fodder, adds antibiotic from January, 2006.In the raisings such as live pig, must not add antibiotic has been internationally recognized food security standard at present.People start to seek one after another safe feed addictive, unaffected to guarantee efficiency and the benefit of animal husbandry production.
At present, 2010 editions feed addictive kinds that the Ministry of Agriculture announces have amino acid, vitamin, mineral element and chelate thereof, enzyme preparation, microorganism, nonprotein nitrogen, antioxidant, anticorrisive agent, mould inhibitor and acidity regulator, colouring agent, flavor enhancement and spices, binding agent, anti-caking agent and stabilizing agent, polysaccharide and oligosaccharides etc.Common on the market, and the feed addictive of most study have following several, probiotic additive, prebiotics additive, trophism element additive, Chinese herb feed additive etc.
Additive for microbe feedstuff is the biologic product that the beneficial microbe of employing Ministry of Agriculture approval is made through fermentation, is antibiotic best substitute.For improving artificial cultivation flora and the metabolite thereof of the general level of the health of poultry, fowl, the micro-ecological disturbance in capable of regulating poultry, fowl body, keeps microecological balance.Be to excite the breeding of animal self probiotics to increase, resist the microbial product of harmful fungus strain growth simultaneously.Bacterial classification as additive for microbe feedstuff mainly comprises bacillus, genus lactubacillus, streptococcus, also comprises in addition yeast, Bifidobacterium and part mould.
Prebiotics claim again chemical probiotic, previous existence element etc., refer to optionally one or more beneficial bacterium growth and breedings in stimulating animal intestines, and not by a class material of Host Digestion.Studying at present and apply more prebiotics is mainly compound sugar, the large class of acidulant two.Thereby functional oligose is a kind of novel, green feed additive, it can be bred beneficial bacterium, suppress pathogen regulating intestinal canal microecosystem and can be produced SCFA, vitamin etc. by beneficial bacterium utilization and provide nutrition also can improve lipid metabolism simultaneously and promote the absorption of some mineral matters in daily ration for animal.The compound sugar product of exploitation mainly contains both at home and abroad at present: the kinds such as manna oligosacchride, Isomaltotriose, FOS, the few glucose of a-, few lactose, few wood sugar, low caramelan.Wherein manna oligosaccharide refers to the little aggressiveness that 2-3 monosaccharide units connects into by glycosidic linkage, due to its specific molecular structure, makes its enzyme hydrolysis that can not be secreted by nonruminant self, but after back segment enteron aisle, can be utilized by probiotic.There are some researches show, manna oligosaccharide can promote daily gain and the efficiency of feed utilization of broiler chicken, improves the egg laying performance of laying hen.Meanwhile, also have some researchs to find, manna oligosaccharide can improve the feed intake of pig, efficiency of feed utilization, daily gain.
Vitamin is the material with high biological activity, and it can not heat supply, can not be as the raw material that forms body.They are mainly with the number of chemical reaction of the form wide participation livestock and poultry internal metabolism of coenzyme and catalyst, thereby guarantee that eucaryotic cell structure and the function of livestock and poultry body tissue organ are normal, to maintain health and the various activity in production of animal.If hypovitaminosis, can cause animal body metabolic disorder, produce a series of deficiency diseases, unhealthful and production performance, can cause animal dead when serious.
Chinese herbal feed additive, has promotion body growth and grows, improves the metabolism of body, improves all multiactions such as body's immunity, disease preventing and treating.Chinese herb feed additive also has advantages of that antibiotic cannot possess, and toxic and side effect is little, can not develop immunity to drugs or the resistance to the action of a drug is little and noresidue.Astragalus polyose has as feed addictive the animal digestion of promotion and absorbs, and improves food conversion ratio and production performance, and disease preventing and treating, improves animal health condition, regulates the good actions such as body non-specific immune function, by many scholars, is confirmed.Research shows, astragalus polyose can promote the growth of Bifidobacterium and lactic acid bacteria, has the effect of probiotic.Therefore, in feed, the appropriate astragalus polyose that adds, can reach health care growth promoting function.Also experiment showed, and in feed, add astragalus polyose, than the meat feed ratio of control group increase, the speed of growth is obviously accelerated, survival rate can improve 3-5%, has also reduced the superseded death rate simultaneously.
Although above-mentioned various additive plays very important effect in animal growth process, because various additives action mechanisms are different, also different to the action effect of the animal of different genera animal and different physiological situations.In order to bring into play better the health-care effect of these feed addictives to animal, there is on the market at present the composition of two kinds or two or more feed addictives, in breeding production, also played good effect.But when combining there are no probio, prebiotics, vitamin, Chinese herb feed additive, there is plurality of health care functions such as maintaining the gut flora ecological balance, raising feed intake, promotion growth, raising immunologic function in the compound additive of one.
Summary of the invention
The object of the present invention is to provide a kind of animal health composition.Another object of the present invention is to provide preparation method and the purposes of said composition.
The invention provides a kind of animal health composition, the raw material that contains following consumption in every 1Kg composition:
Wherein, described probio is selected from one or more the combination in bacillus, genus lactubacillus, streptococcus, yeast, Bifidobacterium; Compound sugar is one or more the combination being selected from the few glucose of manna oligosacchride, Isomaltotriose, FOS, a-, few lactose, few wood sugar, low caramelan; Vitamin is selected from one or more the combination in vitamin A, B, C, D, E family.
Further, the raw material that contains following consumption in every 1Kg composition:
Preferably, the raw material that contains following consumption in every 1Kg composition:
Wherein, described bacillus subtilis or bacillus licheniformis, every gram of total viable count>=95 * 10
8cfu.
The present invention also provides the preparation method of above-mentioned animal health composition, and it comprises following operating procedure:
(1) by proportioning, take raw material;
(2) get each raw material, after mixing, obtain animal health composition.
The present invention also provides above-mentioned animal health composition to improve the purposes in the additive of jenny production performance, anti-trophism diarrhea in preparation.
Further, described jenny is sow.
The present invention also provides the purposes of above-mentioned animal health composition in the additive of the anti-animal nutritional diarrhea of preparation.
Further, described animal is piglet, growing and fattening pigs, sow.
Health composition of the present invention is mainly by bacillus subtilis, bacillus licheniformis, mannan-oligosaccharides, vitamin A, vitamin D
3, vitamin E, Cobastab
1, Cobastab
2, Cobastab
6, the composition such as vitamin C, sodium chloride, astragalus polyose, various compositions are mutually worked in coordination with, are mutually promoted, and are bringing into play the health-care effect of Synergistic promoting growth of animal, aspect preventing and curing diseases, and have significantly improved the economic worth of aquaculture industry.
Accompanying drawing explanation
Fig. 1 health composition of the present invention is for the health-care effect of sow
Fig. 2 health composition of the present invention is for the health-care effect of weanling pig
Fig. 3 health composition of the present invention is for the health-care effect of growing and fattening pigs
The specific embodiment
The preparation of embodiment 1 present composition
Prescription forms and consumption following (1kg composition):
Preparation method is: first take vitamin and evenly mix, then take the equivalent method of progressively increasing, add successively bacillus subtilis, bacillus licheniformis, mannan-oligosaccharides, sodium chloride, astragalus polyose etc., be fully uniformly mixed.
The preparation of embodiment 2 present compositions
Prescription forms and consumption following (1kg composition):
Preparation method is: first take vitamin and evenly mix, then take the equivalent method of progressively increasing, add successively bacillus subtilis, bacillus licheniformis, mannan-oligosaccharides, sodium chloride, astragalus polyose etc., be fully uniformly mixed.
The preparation of embodiment 3 present compositions
Prescription forms and consumption following (1kg composition):
Preparation method is: first take vitamin and evenly mix, then take the equivalent method of progressively increasing, add successively bacillus subtilis, bacillus licheniformis, mannan-oligosaccharides, sodium chloride, astragalus polyose etc., be fully uniformly mixed.
The preparation of embodiment 4 present compositions
Preparation method: take each raw material, mix.
By test example, illustrate beneficial effect of the present invention below.
The impact test of test example 1 health composition of the present invention on pig growth performance
In order to investigate the combination advantage of health composition of the present invention, this experiment has been compared health composition of the present invention and has been used separately the impact on piglet growth performance such as probiotic additive, manna oligosaccharide, compound vitamin, astragalus polyose.
3.1 animals used as test and grouping
Select that 30 ages in days, body weight are close, 120 of the piglets of physical health, be divided at random 6 groups, i.e. health composition group of the present invention (embodiment 1 preparation, addition 0.1%), probio bacillus subtilis and bacillus licheniformis group (4 * 10
9cfu/kg feed), prebiotics manna oligosaccharide group (addition 0.2%), compound vitamin group (addition 0.08%), astragalus polyose group (addition 0.1%) and control group (additive-free).Each component circle is raised, and each colony house feeding environment is basically identical, and each organizes the initial average weight difference of piglet not remarkable (p>0.05).
Above-mentioned addition, refers to that additive accounts for the ratio of feed weight.
3.2 feeding and management
The test pig duration of test dry mash of feeding, hand stock, keeps piglet free choice feeding and drinking-water, and preliminary trial period 6d carries out disinfection to pig house before test, and preliminary trial period, is carried out transition with testing material, and in house, ground keeps dry, attention temperature and ventilation.Immunity and medication are according to test center < < immune programme for children > > and < < medicine guide > > operation, and record faithfully every day.Feed less duty and add, find that piglet is ill should treat in time.Formal test phase 14d.
3.3 test index
Body weight: carry out individuality by hurdle when on-test (30d) and off-test (44d) and weigh, before weighing, empty stomach 12h, calculates and respectively organize average weight.
Average weight increasing a day: calculate the piglet Average weight increasing a day amount of respectively organizing.Average weight increasing a day=(weigh-head of the equal end of head is initial weight all)/experimental period;
Daily ingestion amount: every day, statistics was respectively organized piglet feed consumption rate, calculated average daily ingestion amount.Daily ingestion amount=(inventory-clout amount)/(an experimental period * number);
Feedstuff-meat ratio: total feed intake/experimental period of experimental period total augment weight.
3.4 result of the test
Each group the results are shown in Table 1 to the impact of growth performance.
The every growth performance index of table 1 piglet
As can be seen from Table 1, it is more approaching that each organizes the initial counterpoise of piglet, and difference is not remarkable.Duration of test health composition group of the present invention daily gain is the highest, all higher than probio bacillus subtilis and bacillus licheniformis group, prebiotics manna oligosaccharide group, compound vitamin group, astragalus polyose group and control group, the Average weight increasing a day of control group is minimum, illustrates that various additives all can play gaining effect to piglet growth.And it is especially obvious with health composition group weightening finish of the present invention.Simultaneously health composition group of the present invention is respectively organized also obviously reduction of feedstuff-meat ratio than other, illustrates that health composition group of the present invention also can bring better economic benefit.
The health-care effect experiment of test example 2 health composition of the present invention to all ages and classes section pig
In order to promote better health composition of the present invention, seminar has carried out the health-care effect experiment of health composition of the present invention to all ages and classes section pig, has also obtained good clinical effectiveness.
4.1 on keeping healthy to sow, and health composition of the present invention is 120 examples on probation altogether, have obtained positive effect.It the results are shown in Figure 1.As can be seen from the figure, health composition of the present invention is for after sow, and the death rate of its reproductive performance and newborn piglet has had obvious improvement.Health composition of the present invention has been obtained obvious effect to the sow of the obstacle of oestrusing, and its obstacle of oestrusing has reduced by 80%.It also reaches respectively 67% and 56% to disease of pregnancy reduced rate and the failed reduced rate of breeding, and the newborn piglet death rate has reduced by 48%.Illustrate, health composition of the present invention has been obtained obvious effect improving on sow production performance.
4.2 on keeping healthy to weanling pig, and health composition of the present invention is 229 examples on probation altogether, have also obtained better effects.It the results are shown in Figure 2.Weanling pig, after using health composition of the present invention, is that the dead mortality of piglet growth speed or the incidence of trophism diarrhea, piglet has all had improvement in various degree.This research shows, with control group comparison, the dead mortality reduced rate of piglet 18%, the incidence of trophism diarrhea has also reduced by 72%, speed of growth growth rate surpasses 8.8%, thereby has brought obvious economic benefit.
4.3 on keeping healthy to growing and fattening pigs, and health composition of the present invention is 210 examples on probation altogether, have shown obvious gaining effect, the results are shown in Figure 3.As can be seen from the figure, use the speed of growth of pig after health composition of the present invention to improve 16%, and food consumption reduces by 6%, therefore, use health composition of the present invention when growing and fattening pigs are brought to health-care effect, also brought better culture benefit.
In sum, health composition of the present invention of the present invention is mainly by bacillus subtilis, bacillus licheniformis, mannan-oligosaccharides, vitamin A, vitamin D
3, vitamin E, Cobastab
1, Cobastab
2, Cobastab
6, the composition such as vitamin C, sodium chloride, astragalus polyose, above-mentioned various compositions are mutually worked in coordination with, are mutually promoted, and are bringing into play the health-care effect of Synergistic promoting growth of animal, aspect preventing and curing diseases, and have significantly improved the economic worth of aquaculture industry.
Claims (8)
1. an animal health composition, is characterized in that: the raw material that contains following consumption in every 1kg composition:
Bacillus subtilis 160 ~ 240g
Bacillus licheniformis 180 ~ 260g
Mannan-oligosaccharides 210 ~ 290g
Vitamin A 900 ~ 1,100 ten thousand IU
Vitamin D
3900 ~ 1,100 ten thousand IU
Vitamin E 30000 ~ 34000IU
Cobastab
11.0 ~ 1.8g
Cobastab
24.7 ~ 5.5g
Cobastab
61.6 ~ 2.4g
Vitamin C 36 ~ 44g
Sodium chloride 110 ~ 190g
Astragalus polyose 80 ~ 120g.
2. animal health composition according to claim 1, is characterized in that: the raw material that contains following consumption in every 1kg composition:
Bacillus subtilis 200g
Bacillus licheniformis 220g
Mannan-oligosaccharides 250g
Vitamin A 1,000 ten thousand IU
Vitamin D
31000 ten thousand IU
Vitamin E 32000IU
Cobastab
11.4g
Cobastab
25.1g
Cobastab
62.0g
Vitamin C 40g
Sodium chloride 150g
Astragalus polyose 100g.
3. animal health composition according to claim 1 and 2, is characterized in that: described bacillus subtilis or bacillus licheniformis, every gram of total viable count>=95 * 10
8cfu.
4. the preparation method of the animal health composition described in claim 1-3 any one, is characterized in that: it comprises following operating procedure:
(1) by proportioning, take raw material;
(2) get each raw material, after mixing, obtain animal health composition.
5. the animal health composition described in claim 1-3 any one improves the purposes in the additive of jenny production performance in preparation.
6. purposes according to claim 5, is characterized in that: described jenny is sow.
Animal health composition described in claim 1-3 any one preparation anti-animal nutritional diarrhea additive in purposes.
8. purposes according to claim 7, is characterized in that: described animal is piglet, growing and fattening pigs, sow.
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013650B (en) * | 2014-05-29 | 2017-06-13 | 东北制药集团沈阳第一制药有限公司 | Bacillus licheniformis and herbal polysaccharide composition and its preparation |
| CN104171421A (en) * | 2014-08-08 | 2014-12-03 | 河南牧翔动物药业有限公司 | Feed additive for conditioning intestines of animals |
| CN104366073A (en) * | 2014-11-03 | 2015-02-25 | 河南联合英伟饲料有限公司 | 4% functional non-antibiotic piglet premix |
| CN104381694A (en) * | 2014-11-29 | 2015-03-04 | 郑州后羿制药有限公司 | Composite microecological preparation |
| CN104814285A (en) * | 2015-04-27 | 2015-08-05 | 金华傲农生物科技有限公司 | A premixing agent for shortening sow birth process and a feeding method thereof |
| CN106798122A (en) * | 2016-12-29 | 2017-06-06 | 广州傲农生物科技有限公司 | A kind of pre-mixing agent for improving sow production performance and preparation method and application |
| CN106578535A (en) * | 2016-12-30 | 2017-04-26 | 河南金百合生物科技股份有限公司 | Fattening pig feed additive and preparation method thereof |
| CN107950756A (en) * | 2017-12-21 | 2018-04-24 | 成都欣牧生物科技有限公司 | A kind of feed addictive for improving livestock and poultry production performance and its preparation method and application |
| CN110663814A (en) * | 2019-11-18 | 2020-01-10 | 河南黑马动物药业有限公司 | Mixed traditional Chinese medicine fermented feed additive for livestock and preparation method thereof |
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