CN103301316B - Traditional Chinese medicine composition for treating Intermin-gled phlegm and blood stasis syndrome globus hystericus - Google Patents

Traditional Chinese medicine composition for treating Intermin-gled phlegm and blood stasis syndrome globus hystericus Download PDF

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CN103301316B
CN103301316B CN201310244392.1A CN201310244392A CN103301316B CN 103301316 B CN103301316 B CN 103301316B CN 201310244392 A CN201310244392 A CN 201310244392A CN 103301316 B CN103301316 B CN 103301316B
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chinese medicine
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blood stasis
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孙丽云
刘建俊
庄瑞花
付传翠
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Abstract

The invention discloses a traditional Chinese medicine composition for treating intermin-gled phlegm and blood stasis syndrome globus hystericus. The traditional Chinese medicine composition is prepared from rubus pirifolius smith, cordyline fruticosa, mulgedium sibiricum, rhizoma corydalis, plum blossom, cape jasmine leaves, lotus corniculatus, polygonum cuspidatum, angelica sinensis, orange peel, calanthe graciliflora, earthworm, atractylodes macrocephala and achyranthes bidentata. The composition can be clinically used for treating intermin-gled phlegm and blood stasis syndrome globus hystericus.

Description

A kind of Chinese medicine composition for the treatment of syndrome of intermin-gled phlegm and blood stasis globus hystericus
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of syndrome of intermin-gled phlegm and blood stasis globus hystericus.
Background technology
Globus hystericus refers to foreign body in pharynx sense and blocks as prunus mume (sieb.) sieb.et zucc. core, not out, the lower disease for principal character of pharynx.The pharyngeal neurosis of western medicine is similar to it, locates organic disease but will get rid of throat, trachea, esophagus, cervical vertebra etc. in medical diagnosis on disease process.The primary disease traditional Chinese medical science is recorded in " Medical Treasures of the Golden Chamber the miscellaneous internal diseases in woman arteries and veins disease is also controlled " the earliest, say " in married woman pharynx if any processing a small slice of meat, BANXIA HOUPU TANG master it." mostly to be feelings will unsuccessful for its cause of disease, depression of liver-QI, liver-stagnation spleen-deficiency, not removing dampness of spleen, phlegm caused by accumulation of body fluid, stagnation of Qi and phelgm causes in throat.Primary disease is apt to occur in adult female most clinically, due to the foreign body sensation of throat, often makes patient weighed down with anxieties, and mental burden is overweight, even has serious probably cancer psychology, so that the normal work of impact and life.Syndrome of intermin-gled phlegm and blood stasis globus hystericus symptom comprises the pharyngeal dry causalgia of itching, and zest dry cough, has foreign body sensation in pharynx, tell under pharynx not, time have unsmooth sense or pain, can be with dry pharynx, pain in chest and hypochondrium, vague epigastralgia, body of the tongue is dark violet or press from both sides ecchymosis, thick and greasy fur, and deep and hesitant pulse, controls and work as promoting the circulation of QI and reducing phlegm, vital energy regualting and blood circulation-promoting, sore-throat relieving eliminating stagnation.Draw through inventor's long-term practice, Chinese medicine is controlled syndrome of intermin-gled phlegm and blood stasis globus hystericus and is had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment syndrome of intermin-gled phlegm and blood stasis globus hystericus that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Rubi pirifolii, Cordyline fruticosa, Herba Lactucae Indicae, Rhizoma Corydalis, Flos Mume, Folium Gardeniae, Radix Loti Corniculati, Rhizoma Polygoni Cuspidati, Radix Angelicae Sinensis, Pericarpium Citri junoris, Calanthe hamata-Mand (-Mazz), Pheretima, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make Radix Rubi pirifolii 20-40 part, Cordyline fruticosa 20-30 part, Herba Lactucae Indicae 20-30 part, Rhizoma Corydalis 20-30 part, Flos Mume 15-25 part, Folium Gardeniae 15-25 part, Radix Loti Corniculati 15-25 part, Rhizoma Polygoni Cuspidati 15-25 part, Radix Angelicae Sinensis 10-18 part, Pericarpium Citri junoris 10-18 part, Calanthe hamata-Mand (-Mazz) 10-15 part, Pheretima 6-10 part, Rhizoma Atractylodis Macrocephalae 8-15 part, Radix Achyranthis Bidentatae 8-15 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is 30 parts of: Radix Rubi pirifolii, 25 parts of Cordyline fruticosa, 25 parts of Herba Lactucae Indicaes, 25 parts of Rhizoma Corydalis, 20 parts, Flos Mume, 20 parts of Folium Gardeniae, 20 parts of Radix Loti Corniculatis, 20 parts of Rhizoma Polygoni Cuspidati, 14 parts of Radix Angelicae Sinensis, 14 parts of Pericarpium Citri junoriss, 12 parts of Calanthe hamata-Mand (-Mazzies, 8 parts of Pheretimas, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Achyranthis Bidentataes.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Rubi pirifolii: sour, puckery, cool.Return lung, Liver Channel.Clearing away lung-heat to relieve cough, promoting QI circulation for relieving depression.Clinical in cough due to lung-heat, stagnation of QI hypochondriac pain, the diseases such as abdominal distention.
Cordyline fruticosa: sweet, light, cool.Removing heat-phlegm, cooling blood for hemostasis.For phlegm-fire cough, spitting of blood, spits blood, hematuria, metrorrhagia, bleeding hemorrhoids etc.
Herba Lactucae Indicae: bitter, cold.Heat-clearing and toxic substances removing, invigorates blood circulation, hemostasis.Clinical in laryngopharynx swelling and pain, acute appendicitis, furuncle toxic swelling, cervicitis, postnatal blood stasis raw meat pain, wart tumor, metrorrhagia, the diseases such as bleeding hemorrhoids.
Rhizoma Corydalis: acrid, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.For all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.
Flos Mume: bitter, sweet, micro-acid, cool.Return liver, stomach, lung meridian.Dispersing the stagnated live-QI to relieve the stagnation of QI, appetizing is promoted the production of body fluid, and reduces phlegm.Clinical in diseases such as gloomy vexed, stomachache due to hyperactive liver-QI attacking the stomach, globus hystericus, scrofula sores.
Folium Gardeniae: bitter, puckery, cold.Return lung, liver, kidney channel.Promoting blood circulation and detumescence, heat-clearing and toxic substances removing.For traumatic injury, furunculosis, hemorrhoid, primary sore etc.
Radix Loti Corniculati: sweet, bitter, be slightly cold.Return lung meridian.Tonify deficiency, heat clearing away, quenches the thirst.For asthenia, fever due to yin deficiency, thirsty etc.
Rhizoma Polygoni Cuspidati: bitter, cold.Return liver, gallbladder, lung meridian.Promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough.For jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, carbuncle sore tumefacting virus, venom, cough due to lung-heat etc.
Radix Angelicae Sinensis: sweet, pungent, warm, return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, regulating menstruation, pain relieving.For heart-liver blood deficiency, ulcer sores.
Pericarpium Citri junoris: acrid, bitter, warm.Return spleen, lung meridian.Circulation of qi promoting spleen invigorating, lowering the adverse-rising QI and eliminating phlegm.The clinical distension and fullness in the abdomen for stagnation of QI in spleen and stomach, nausea and vomiting, inappetence, expectorant is stopped up the cough with copious phlegm of QI rising in reverse order, and septum pectorale is full vexed, the diseases such as globus hystericus.
Calanthe hamata-Mand (-Mazz): pungent, bitter, cold.Return liver, lung, kidney channel.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Clinical in laryngopharynx swelling and pain, hemorrhoid, proctoptosis, rheumatic arthralgia, the diseases such as traumatic injury.
Pheretima: salty, cold.Return lung, liver, kidney channel.Relieving convulsion, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and dredging collateral is relievingd asthma.Cure mainly calentura heating manic, infantile convulsion is twitched, rheumatism hemiplegia, the cards such as cough due to lung-heat.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.For deficiency of spleen-QI and stomach-QI, transporting is unable, anorexia and loose stool, and distension and fullness in the abdomen, insufficiency of the spleen water retention, and be phlegm retention, edema, dysuria, frequent fetal movement etc.
Radix Achyranthis Bidentatae: bitter, sweet, sour, flat.Return liver, kidney channel.Promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis, ignites descending.For amenorrhea, dysmenorrhea, the menoxenia of stagnation of blood stasis, lumbago due to renal deficiency and lingering arthralgia soreness of waist and knee joint are weak, headache, and dizzy grade intimately goes up the card of inflammation.
The clinical manifestation of syndrome of intermin-gled phlegm and blood stasis globus hystericus is: the pharyngeal dry causalgia of itching, zest dry cough, has foreign body sensation in pharynx, tell under pharynx not, time have unsmooth sense or pain, can be with dry pharynx, pain in chest and hypochondrium, vague epigastralgia, body of the tongue dark violet or folder ecchymosis, thick and greasy fur, deep and hesitant pulse.Control and work as promoting the circulation of QI and reducing phlegm, vital energy regualting and blood circulation-promoting, sore-throat relieving eliminating stagnation.Zhong Radix Rubi pirifolii of the present invention promoting QI circulation for relieving depression, are monarch drug, Cordyline fruticosa removing heat-phlegm, Herba Lactucae Indicae heat-clearing and toxic substances removing, invigorate blood circulation, Rhizoma Corydalis blood circulation promoting regulates qi, eliminating stasis to stop pain, be ministerial drug, Flos Mume resolving depression, promote the production of body fluid, reduce phlegm, Folium Gardeniae heat-clearing and toxic substances removing, promoting blood circulation and detumescence, Radix Loti Corniculati heat clearing away, Rhizoma Polygoni Cuspidati heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, Radix Angelicae Sinensis promoting blood circulation and stopping pain, Pericarpium Citri junoris circulation of qi promoting spleen invigorating, reduces phlegm, Calanthe hamata-Mand (-Mazz) heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, Pheretima dredging collateral, Rhizoma Atractylodis Macrocephalae spleen invigorating, Radix Achyranthis Bidentatae is invigorated blood circulation.All medicines share plays promoting the circulation of QI and reducing phlegm altogether, vital energy regualting and blood circulation-promoting, and effect of sore-throat relieving eliminating stagnation, finds that through clinical practice syndrome of intermin-gled phlegm and blood stasis globus hystericus is had to unique curative effect.
Chinese medicine composition of the present invention was in 2005 to 2012 clinical observation syndrome of intermin-gled phlegm and blood stasis globus hystericus 72 routine patients, and clinical report is as follows:
1, physical data
In 72 routine patients, male 31 examples, female's 41 examples, age 18-69 year, the course of disease is many at 20 days to 2 years, 35 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
In the conscious throat of patient, have abnormal sensory, if any thing stalk, not out, can not swallow, and there is no pain, does not hinder diet.Its symptom often changes with the fluctuation of feelings will, time heavy when light.Inspect throat, there is no abnormal, though or have variation, also very slight.General Symptoms, patient is every sees spirit depressing, many doubts, fullness and distention in the chest and hypochondrium, indigestion and loss of appetite, sleepy, become thin, loose stool, the common menoxenia of women, dark tongue quality is stagnant, stringy pulse.The clinical manifestation of syndrome of intermin-gled phlegm and blood stasis globus hystericus is: the pharyngeal dry causalgia of itching, zest dry cough, in pharynx, have foreign body sensation, tell under pharynx not, time have unsmooth sense or pain, can be with dry pharynx, pain in chest and hypochondrium, vague epigastralgia, body of the tongue dark violet or folder ecchymosis, thick and greasy fur, deep and hesitant pulse, and all get rid of bottleneck throat, Esophageal tumor and other pathological changes.
3, Therapeutic Method
3.1 prescription: Radix Rubi pirifolii 30g, Cordyline fruticosa 25g, Herba Lactucae Indicae 25g, Rhizoma Corydalis 25g, Flos Mume 20g, Folium Gardeniae 20g, Radix Loti Corniculati 20g, Rhizoma Polygoni Cuspidati 20g, Radix Angelicae Sinensis 14g, Pericarpium Citri junoris 14g, Calanthe hamata-Mand (-Mazz) 12g, Pheretima 8g, Rhizoma Atractylodis Macrocephalae 12g, Radix Achyranthis Bidentatae 10g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 5 days were 1 course for the treatment of at 1 dose of every day.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Cure: various clinical symptoms disappear completely and laryngo-pharyngoscopy without extremely, within 1 year, do not recur above;
Effective: clinical symptoms disappears substantially or completely, laryngo-pharyngoscopy is without abnormal or basic;
Effective: clinical cardinal symptom alleviates or part disappears, and laryngo-pharyngoscopy is not improved, or recurrence again after drug withdrawal;
Invalid: symptom is without improvement.
4.2 results: in 72 routine patients, cure 44 examples (61.1%), effective 17 examples (23.6%), effective 11 examples (15.3%), invalid 0 example (0%), total effective rate is 100%.
5, model case
5.1 Zhao, female, 33 years old, disease see pharyngeal dry itch pain, xerostomia, dry cough battle array do, pain in chest and hypochondrium, vague epigastralgia, time have retch, in pharynx, have foreign body sensation, body of the tongue is dark violet, thick and greasy fur, deep and hesitant pulse.Look into pharyngeal congestion.Be diagnosed as syndrome of intermin-gled phlegm and blood stasis globus hystericus.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
5.2 Mas, female, 52 years old, pharyngeal dry itching, zest dry cough, has foreign body sensation in pharynx, with thick sputum, difficulty in expectorating, epigastric distension and distress, total feel is tired, body of the tongue folder ecchymosis, thick and greasy fur, deep pulse, and all get rid of bottleneck throat, Esophageal tumor and other pathological changes.Be diagnosed as syndrome of intermin-gled phlegm and blood stasis globus hystericus.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
5.3 Cai, man, 45 years old, pharyngeal discomfort in recent years more than.Because there is pharyngeal pain after catching a cold, through doctor trained in Western medicine infection, transference cure after symptomatic treatment, the after this pharyngeal discomfort of normal feel, seemingly there is thing to stop up, that tells does not go out, and occasionally has puckery pain, takes repeatly the weary effect of Chinese and western drugs, recently above-mentioned symptom increases the weight of, companion's two side of body distending pains, check that through department of eye pharyngeal congestion is not obvious, a little folliculus as seen.Body of the tongue is dark violet, there is ecchymosis on limit, deep pulse.Be diagnosed as syndrome of intermin-gled phlegm and blood stasis globus hystericus.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, treating a Chinese medicine composition for syndrome of intermin-gled phlegm and blood stasis globus hystericus, is that You Radix Rubi pirifolii 20g, Cordyline fruticosa 20g, Herba Lactucae Indicae 20g, Rhizoma Corydalis 20g, Flos Mume 15g, Folium Gardeniae 15g, Radix Loti Corniculati 15g, Rhizoma Polygoni Cuspidati 15g, Radix Angelicae Sinensis 10g, Pericarpium Citri junoris 10g, Calanthe hamata-Mand (-Mazz) 10g, Pheretima 6g, Rhizoma Atractylodis Macrocephalae 8g, Radix Achyranthis Bidentatae 8g make.
Embodiment 2, treating a Chinese medicine composition for syndrome of intermin-gled phlegm and blood stasis globus hystericus, is that You Radix Rubi pirifolii 30g, Cordyline fruticosa 25g, Herba Lactucae Indicae 25g, Rhizoma Corydalis 25g, Flos Mume 20g, Folium Gardeniae 20g, Radix Loti Corniculati 20g, Rhizoma Polygoni Cuspidati 20g, Radix Angelicae Sinensis 14g, Pericarpium Citri junoris 14g, Calanthe hamata-Mand (-Mazz) 12g, Pheretima 8g, Rhizoma Atractylodis Macrocephalae 12g, Radix Achyranthis Bidentatae 10g make.
Embodiment 3, treating a Chinese medicine composition for syndrome of intermin-gled phlegm and blood stasis globus hystericus, is that You Radix Rubi pirifolii 40g, Cordyline fruticosa 30g, Herba Lactucae Indicae 30g, Rhizoma Corydalis 30g, Flos Mume 25g, Folium Gardeniae 25g, Radix Loti Corniculati 25g, Rhizoma Polygoni Cuspidati 25g, Radix Angelicae Sinensis 18g, Pericarpium Citri junoris 18g, Calanthe hamata-Mand (-Mazz) 15g, Pheretima 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Achyranthis Bidentatae 15g make.

Claims (2)

1. treat a Chinese medicine composition for syndrome of intermin-gled phlegm and blood stasis globus hystericus, it is characterized in that it is to be made up of following raw material medicaments:
Radix Rubi pirifolii 20-40 part, Cordyline fruticosa 20-30 part, Herba Lactucae Indicae 20-30 part, Rhizoma Corydalis 20-30 part,
Flos Mume 15-25 part, Folium Gardeniae 15-25 part, Radix Loti Corniculati 15-25 part, Rhizoma Polygoni Cuspidati 15-25 part,
Radix Angelicae Sinensis 10-18 part, Pericarpium Citri junoris 10-18 part, Calanthe hamata-Mand (-Mazz) 10-15 part, Pheretima 6-10 part,
Rhizoma Atractylodis Macrocephalae 8-15 part, Radix Achyranthis Bidentatae 8-15 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made up of following raw material medicaments:
30 parts of Radix Rubi pirifolii, 25 parts of Cordyline fruticosa, 25 parts of Herba Lactucae Indicaes, 25 parts of Rhizoma Corydalis,
20 parts, Flos Mume, 20 parts of Folium Gardeniae, 20 parts of Radix Loti Corniculatis, 20 parts of Rhizoma Polygoni Cuspidati,
14 parts of Radix Angelicae Sinensis, 14 parts of Pericarpium Citri junoriss, 12 parts of Calanthe hamata-Mand (-Mazzies, 8 parts of Pheretimas,
12 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Achyranthis Bidentataes.
CN201310244392.1A 2013-06-06 2013-06-06 Traditional Chinese medicine composition for treating Intermin-gled phlegm and blood stasis syndrome globus hystericus Expired - Fee Related CN103301316B (en)

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