CN103285330B - Traditional Chinese medicine for treating uterine fibroid and preparation method thereof - Google Patents
Traditional Chinese medicine for treating uterine fibroid and preparation method thereof Download PDFInfo
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- CN103285330B CN103285330B CN201310237359.6A CN201310237359A CN103285330B CN 103285330 B CN103285330 B CN 103285330B CN 201310237359 A CN201310237359 A CN 201310237359A CN 103285330 B CN103285330 B CN 103285330B
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Abstract
The invention discloses a traditional Chinese medicine for treating uterine fibroid and a preparation method thereof. The traditional Chinese medicine is prepared from the following medicinal materials in mass fraction: 15 to 18 parts of lobelia chinensis, 13 to 18 parts of poria cocos, 13 to 18 parts of radix paeoniae alba, 13 to 18 parts of cassia twig, 20 to 26 parts of rhizoma atractylodis macrocephalae, 7 to 12 parts of liquorice, 30 to 40 parts of curcuma zedoary, 10 to 14 parts of angelica sinensis, 14 to 16 parts of cortex moutan radicis, 30 to 40 parts of rhizoma sparganii, 12 to 17 parts of carthamus tinctorius, 10 to 14 parts of peach kernel, 20 to 26 parts of bock greenbrier rhizome, 15 to 25 parts of spina gleditsiae, 20 to 26 parts of myrrh, and 12 to 16 parts of achyranthes bidentata. The preparation method comprises the following steps of: respectively cleaning, drying, crushing and disinfecting the medicinal materials; mixing in proportion according to a prescription; adding water to dip; feeding steam to heat until boiling at three times; filtering; preparing the liquid medicine into an extract; drying again and crushing and grinding into powder; then pressing into troches or filling into capsules. The traditional Chinese medicine has a good therapeutic effect, can be used for increasing the varieties of medicines for treating uterine fibroid, and is suitable for being used for treating a patient suffering from uterine fibroid.
Description
Technical field
The present invention relates to medicinal preparation, in particular to the medicine by prepared from traditional Chinese medicines, furthermore, relate to the medicine for the treatment of hysteromyoma.
Background technology
Hysteromyoma (
myoma of uterus), also known as leiomyoma of uterus, be the modal a kind of benign tumors of female sex organs.How asymptomatic, minority shows as vaginal hemorrhage, and abdominal part touches swollen thing and pressure symptom etc.As can pain be caused when there is torsion of pedicle or other situations.Common with multiple myomata.
The treatment of China's medical science to hysteromyoma has very rich experience.In recent years, the pharmaceutical formulation application for the treatment of hysteromyoma Chinese patent is related in a large number.Such as, No. 200710065486.7 " a kind of Chinese medicine preparation for the treatment of hysteromyoma ", No. 200810057976.7 " compound Chinese medicinal preparation for the treatment of hysteromyoma and preparation method thereof ", No. 200910016633.0 " a kind of Chinese medicine composition of thorough elimination hysteromyoma ", No. 201010203446.6 " a kind of compound Chinese medicinal preparation for the treatment of hysteromyoma ", No. 201110204302.7 " a kind of Chinese medicines for the treatment of hysteromyoma " and No. 201210063716.7 " a kind of Chinese medicines for the treatment of hysteromyoma " etc.These medicines no doubt have certain curative effect, but how on earth curative effect there is no from understanding, so people still upgrade in exploration and research, more effective medicine, are the health service of women.
Summary of the invention
Object of the present invention is just to provide a kind of Chinese medicine for the treatment of hysteromyoma, increases the types of drugs for the treatment of hysteromyoma, eliminates the misery of women patient and the harm to WomanHealth.
Another object of the present invention is to provide the method for making of above-mentioned Chinese medicine, enables practical application.
The Chinese medicine for the treatment of hysteromyoma of the present invention is made up of the medical material of following quality proportioning:
Herba Lobeliae Chinensis 15 ~ 18, Poria 13 ~ 18, Radix Paeoniae Alba 13 ~ 18, Ramulus Cinnamomi 13 ~ 18, the Rhizoma Atractylodis Macrocephalae 20 ~ 26, Radix Glycyrrhizae 7 ~ 12, Rhizoma Curcumae 30 ~ 40, Radix Angelicae Sinensis 10 ~ 14, Cortex Moutan 14 ~ 16, Rhizoma Sparganii 30 ~ 40, Flos Carthami 12 ~ 17, Semen Persicae 10 ~ 14, Rhizoma Smilacis Bockii 20 ~ 26, Spina Gleditsiae 15 ~ 25, Myrrha 20 ~ 26, Radix Achyranthis Bidentatae 12 ~ 16.
The preferred mass proportioning of this Chinese medicine is:
Herba Lobeliae Chinensis 15, Poria 16, Radix Paeoniae Alba 16, Ramulus Cinnamomi 16, the Rhizoma Atractylodis Macrocephalae 24, Radix Glycyrrhizae 10, Rhizoma Curcumae 35, Radix Angelicae Sinensis 12, Cortex Moutan 15, Rhizoma Sparganii 36, Flos Carthami 15, Semen Persicae 12, Rhizoma Smilacis Bockii 23, Spina Gleditsiae 20, Myrrha 23, Radix Achyranthis Bidentatae 14.
In above-mentioned formula,
herba Lobeliae Chinensisfor Campanulaceae Herba Lobeliae Chinensis (
lobelia chinensis) whole herb with root, sweet in the mouth, property is put down, and has diuretic, detumescence, detoxicating functions (compiling " Chinese crude drug voluminous dictionary " 780 pages see the new medical college in Jiangsu);
poriafor Polyporaceae plant Poria (
poria cocos) dry sclerotia, slightly sweet flavor, property is put down, and has the effect (see " Chinese medicine voluminous dictionary " 1596 pages) of eliminating dampness and diuresis, happy Fructus Alpiniae Oxyphyllae;
radix Paeoniae Albafor ranunculaceae plant Radix Paeoniae (
paeonia lactiflora) root, bitter in the mouth acid, cool in nature, have nourish blood, the effect of easing the affected liver, the diseases such as conjunctival congestion (see " Chinese medicine voluminous dictionary " 706 pages) can be controlled;
ramulus Cinnamomifor canella Cortex Cinnamomi (
cinnamomum cassia) twig, acrid-sweet flavor, warm in nature, can diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation (see " Chinese medicine voluminous dictionary " 1771 pages);
the Rhizoma Atractylodis Macrocephalaefor the feverfew Rhizoma Atractylodis Macrocephalae (
atractylodes macrocephala) rhizome, bitter but sweet flavor, warm in nature, can spleen reinforcing, stomach reinforcing, dampness and in (see " Chinese medicine voluminous dictionary " 670 pages);
radix Glycyrrhizaefor glycyrrhizic legume (
glycyrrhiza uralensis) rhizome, sweet in the mouth, property are flat, have and middle emergency, lung moistening, removing toxic substances, invigorating the spleen and replenishing QI effect (see " Chinese medicine voluminous dictionary " 567 pages);
rhizoma Curcumaefor zingiberaceous plant Rhizoma Curcumae (
curcuma lzedoaria) rhizome, acrid in the mouth is bitter, warm in nature, has circulation of qi promoting, removing blood stasis, removing food stagnancy, analgesic efficacy (see " Chinese medicine voluminous dictionary " 2450 pages);
radix Angelicae Sinensisfor umbelliferae angelica (
angelica sinensis) root, sweet in the mouth is pungent, warm in nature, has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes the effect of laxation, can control menoxenia, headache due to deficiency of blood, dizzy, numbness of withering (see " Chinese medicine voluminous dictionary " 876 pages);
cortex Moutanfor ranunculaceae peony (
paeonia suffruticosa) root bark, acrid in the mouth is bitter, cool in nature, can heat clearing away, removing heat from blood, and blood, repercussive (see " Chinese medicine voluminous dictionary " 1127 pages);
rhizoma Sparganiifor Sparganiaceae plant rhizoma scirpi (
sparganium stoloniferum) tuber, sweet in the mouth is worked hard, and property is put down, can removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving (see " Chinese medicine voluminous dictionary " 56 pages);
flos Carthamifor irides Stigma Croci (
crocus sativus) top of style and stigma, sweet in the mouth, property is put down, can blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens (see " Chinese medicine voluminous dictionary " 2671 pages);
semen Persicae, for rosaceous plant Fructus Persicae (
prunus percisa) seed, bitter but sweet flavor, property is put down, and has blood stasis removing and clots absorbing, moistens the effect of hot-tempered laxation (see " Chinese medicine voluminous dictionary " 1787 pages);
rhizoma Smilacis Bockiifor liliaceous plant southwest Rhizoma Smilacis Chinensis (
smilax bockii) rhizome, taste is micro-pungent, warm in nature, can expelling wind and activating blood circulation removing toxic substances (see " Chinese crude drug voluminous dictionary " 201 pages);
spina Gleditsiaefor leguminous plant Fructus Gleditsia (
gleditsia sinensis) Spina jujubae, acrid in the mouth, warm in nature, can wind be searched, toxin expelling, detumescence, draw out the pus (see " Chinese medicine voluminous dictionary " 1145 pages);
myrrhafor olive subject plant myrrh (
commiphora myrrha) gum resin, bitter in the mouth, property put down, can fall apart blood, blood stasis removing, subside a swelling, analgesic therapy (see " Chinese medicine voluminous dictionary " 1167 pages);
radix Achyranthis Bidentatae,for amaranthaceous plant Radix Achyranthis Bidentatae (
achyranthes bidentata) root, sweet in the mouth picric acid, property is put down, and has the effect (see " Chinese medicine voluminous dictionary " 417 pages) of dissipating blood stasis blood, subduing inflammation.
Above-mentioned medical material should meet the regulation in " Chinese Pharmacopoeia " nineteen ninety-five version one under each medical material item.
The Chinese medicine method for making for the treatment of hysteromyoma is cleaned respectively by above-mentioned 16 taste medical materials, with hot-air seasoning, is processed into fragment, then uses disinfection by ultraviolet light; After pressing formula proportion mixing again, put into the pond that pottery or copper tank or wooden barrel or cement be built into and add water retting, and pass into steam heated to boiling 3 times, 1 ~ 2 hour first time, second time 0.5 ~ 1 hour, 0.5 hour third time, so far wherein active ingredient proposes substantially; After filtering, extractum made by medicinal liquid; Fire drying in using again, pulverizes, grinds to form 60 order powder; Last pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every sheet 1g, obtains tablet or capsule.
The above-mentioned pharmaceutical technology being pressed into tablet comprises: 1. 60 obtained order powder are added adjuvant, main adjuvant is adhesive modified starch, mix homogeneously; 2. add water in mixed powder as wetting agent, make soft material; 3. soft material extruding is sieved, make granule; 4. granule is through super-dry, make its moisture be applicable to and evenly, grain graininess is suitable; 5. dried particles is through inspection, confirms the requirement meeting tablet; 6. extrude tablet with Chong Yashi or rotary tablet machine, what be up to the standards is finished product.
The pharmaceutical technology of above-mentioned capsule comprises: 1. preparing or buying with gelatin is the capsulae vacuus of primary raw material; 2. 60 obtained order powder are crossed No. 6 sieves, the fine powder obtained is for subsequent use; 3. enter soft capsule with artificial medicated powder of loading, or load medicated powder with automatic filling machine; 4. test to the effective ingredient of medicated powder and quality, the glue of qualified rear gelatin, in the sealing of capsule capping place, obtains finished product.
Inventor points out: this Chinese medicine also can be prepared into any one by conventional method of Chinese medicinal and commonly use peroral dosage form.No matter which kind of dosage form, all must deposit according to the relevant regulations of drug stock control.
The Chinese medicine using method of hysteromyoma of the present invention is oral, warm water delivery service, every day 2 times, each 4 ~ 5/sheet.
The Chinese medicine for the treatment of hysteromyoma of the present invention puts into practice in long term medical the formula drawn.At Clinical practice for many years, be total to Ureteral Calculus 34 patients with uterin leiomyoma patient (making a definite diagnosis by regular examination in hospital), the age is between 27 ~ 50 years old for Chinese medicine of the present invention, the longest 260 days of medicine time, 20 days that take medicine minimum, wherein muscular tumor disappeared, reach clinical cure 26 people, effective 5 people, 3 people are invalid.Model case is as follows:
Case one: Zhang Anqun, female, 43 years old, employee.Calendar year 2001, find left lower abdominal pain, menstruation is abnormal, unregular vaginal bleeding, fatigue and weak, living examination in hospital is hysteromyoma, once took plurality of Chinese and Western medicine, poor effect, after check through another hospital of family again, left lower quadrant has the enclosed mass that inner Fructus Persicae is large, and matter is hard, tenderness, is also diagnosed as hysteromyoma, upon somebody's introduction, take medicine of the present invention after one month, enclosed mass obviously reduces, serve on 2 months enclosed mass all to disappear, follow up a case by regular visits to after 1 year, do not recur.
Case two: yellow Zhu, female, 32 years old.Once long-term " seat platform ", living abnormal, finding that there were abnormal phenomenon of bleeding, particularly sexual intercourse in uterus with bleeding in 2011, and be examination in hospital afterwards, be diagnosed as hysteromyoma.Upon somebody's introduction, take medicine of the present invention 20 days, uterus bleed phenomenon disappear, serve on 60 days, symptom all disappears, and follows up a case by regular visits to, and half a year does not recur.
Case three: Huang little Hua, female, 33 years old.In July, 2009, vagina started to bleed incessantly, the phenomenons such as lumbago, through examination in hospital, its intrauterine has two lumps not of uniform size, be diagnosed as hysteromyoma, upon somebody's introduction, medicine of the present invention is taken after 5 months, the eumenorrhea, phenomenon of bleeding disappears, muscular tumor can not touch, and patient's incoming call is said gratefully: " doctor is that you have rescued my life.”
The Chinese medicine for the treatment of hysteromyoma of the present invention, medical material is easy to get, easy to process, and curative effect is obvious.Be applicable to treat hysteromyoma.
Detailed description of the invention
Above-mentioned 16 taste medical materials are cleaned by embodiment respectively, with hot-air seasoning, are processed into fragment, then use disinfection by ultraviolet light; Get Lobelia chinensis 15g again, Poria 16g, Radix Paeoniae Alba 16g, Ramulus Cinnamomi 16g, Rhizoma Atractylodis Macrocephalae 24g, Radix Glycyrrhizae 10g, Rhizoma Curcumae 35g, Radix Angelicae Sinensis 12g, Cortex Moutan 15g, Rhizoma Sparganii 36g, Flos Carthami 15g, Semen Persicae 12g, Rhizoma Smilacis Bockii 23g, Spina Gleditsiae 20g, Myrrha 23g, Radix Achyranthis Bidentatae 14g, after mixing, put into wooden barrel and add water retting, and pass into steam heated to boiling 3 times, 1 ~ 2 hour first time, second time 0.5 ~ 1 hour, 0.5 hour third time, extremely wherein active ingredient proposes substantially; After filtering, extractum made by medicinal liquid; Fire drying in using again, pulverizes, grinds to form 60 order powder, mix homogeneously; Last pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every sheet 1g, obtains tablet or capsule.
Claims (3)
1. treat a Chinese medicine for hysteromyoma, it is characterized in that this Chinese medicine is made up of the medical material of following quality proportioning:
Lobelia chinensis 15 ~ 18, Poria 13 ~ 18, Radix Paeoniae Alba 13 ~ 18, Ramulus Cinnamomi 13 ~ 18, the Rhizoma Atractylodis Macrocephalae 20 ~ 26, Radix Glycyrrhizae 7 ~ 12, Rhizoma Curcumae 30 ~ 40, Radix Angelicae Sinensis 10 ~ 14, Cortex Moutan 14 ~ 16, Rhizoma Sparganii 30 ~ 40, Flos Carthami 12 ~ 17, Semen Persicae 10 ~ 14, Rhizoma Smilacis Bockii 20 ~ 26, Spina Gleditsiae 15 ~ 25, Myrrha 20 ~ 26, Radix Achyranthis Bidentatae 12 ~ 16.
2., according to Chinese medicine according to claim 1, it is characterized in that this Chinese medicine is made up of the medical material of following quality proportioning:
Lobelia chinensis 15, Poria 16, Radix Paeoniae Alba 16, Ramulus Cinnamomi 16, the Rhizoma Atractylodis Macrocephalae 24, Radix Glycyrrhizae 10, Rhizoma Curcumae 35, Radix Angelicae Sinensis 12, Cortex Moutan 15, Rhizoma Sparganii 36, Flos Carthami 15, Semen Persicae 12, Rhizoma Smilacis Bockii 23, Spina Gleditsiae 20, Myrrha 23, Radix Achyranthis Bidentatae 14.
3. prepare the method for Chinese medicine described in claim 1, it is characterized in that above-mentioned 16 taste medical materials to clean respectively, with hot-air seasoning, be processed into fragment, with disinfection by ultraviolet light; After pressing formula proportion mixing again, put into the pond that pottery or copper tank or wooden barrel or cement be built into and add water retting, and pass into steam heated to boiling 3 times, 1 ~ 2 hour first time, second time 0.5 ~ 1 hour, 0.5 hour third time, so far wherein active ingredient proposes substantially; After filtering, extractum made by medicinal liquid; Fire drying in using again, pulverizes, grinds to form 60 order powder; Last pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every sheet 1g, obtains tablet or capsule.
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| CN104367660B (en) * | 2014-11-19 | 2016-12-28 | 烟台瑞智生物医药科技有限公司 | A kind of Chinese medicine treating phlegm-damp stasis pattern of syndrome abdominal mass |
| CN104784643A (en) * | 2015-04-29 | 2015-07-22 | 赵汝君 | Medicine for treating hysteromyoma, ovarian cyst and endometriosis |
| CN104888157A (en) * | 2015-07-06 | 2015-09-09 | 苗怡文 | Traditional Chinese medicine preparation for treating hysteromyoma and preparation method thereof |
| CN105727197A (en) * | 2016-04-01 | 2016-07-06 | 广州暨南生物医药研究开发基地有限公司 | Pharmaceutical composition containing folium artemisiae argyi for treating myoma of uterus and preparing method thereof |
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| Title |
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| 辜孔进教授运用盆腔八针治疗妇科疾病举隅;黄健琳等;《中医药导报》;20110630;第17卷(第6期);8-9 * |
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