CN103285034A - Medicine for treating chilblain and manufacturing method thereof - Google Patents
Medicine for treating chilblain and manufacturing method thereof Download PDFInfo
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- CN103285034A CN103285034A CN2013102675219A CN201310267521A CN103285034A CN 103285034 A CN103285034 A CN 103285034A CN 2013102675219 A CN2013102675219 A CN 2013102675219A CN 201310267521 A CN201310267521 A CN 201310267521A CN 103285034 A CN103285034 A CN 103285034A
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- 239000003814 drug Substances 0.000 title claims abstract description 58
- 208000010445 Chilblains Diseases 0.000 title claims abstract description 57
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 6
- 229940079593 drug Drugs 0.000 title 1
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims abstract description 87
- 239000000843 powder Substances 0.000 claims abstract description 68
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 63
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims abstract description 42
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims abstract description 42
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 21
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims abstract description 21
- 239000005770 Eugenol Substances 0.000 claims abstract description 21
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229960002217 eugenol Drugs 0.000 claims abstract description 21
- 229960001047 methyl salicylate Drugs 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 21
- 229940099259 vaseline Drugs 0.000 claims abstract description 21
- 241001494479 Pecora Species 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims description 32
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 25
- 241000283898 Ovis Species 0.000 claims description 25
- 229910052799 carbon Inorganic materials 0.000 claims description 25
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 20
- 239000007766 cera flava Substances 0.000 claims description 20
- 229910052740 iodine Inorganic materials 0.000 claims description 20
- 239000011630 iodine Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 16
- 238000005303 weighing Methods 0.000 claims description 16
- 238000000227 grinding Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 13
- 238000009833 condensation Methods 0.000 claims description 8
- 230000005494 condensation Effects 0.000 claims description 8
- 238000001816 cooling Methods 0.000 claims description 8
- 241000628997 Flos Species 0.000 claims description 6
- 241000283690 Bos taurus Species 0.000 claims description 5
- 241000283707 Capra Species 0.000 claims description 5
- 241000282994 Cervidae Species 0.000 claims description 5
- 241000283007 Cervus nippon Species 0.000 claims description 5
- 210000003746 feather Anatomy 0.000 claims description 5
- 241000219322 Dianthus Species 0.000 claims description 3
- 239000008868 Flower Essence Substances 0.000 claims description 3
- 235000018958 Gardenia augusta Nutrition 0.000 claims description 3
- 241001632576 Hyacinthus Species 0.000 claims description 3
- 235000014443 Pyrus communis Nutrition 0.000 claims description 3
- 241000775848 Syringa oblata Species 0.000 claims description 3
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims description 3
- 239000007968 orange flavor Substances 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 239000004166 Lanolin Substances 0.000 abstract 1
- 235000007889 Osmunda cinnamomea Nutrition 0.000 abstract 1
- 244000239204 Plantago lanceolata Species 0.000 abstract 1
- 235000010503 Plantago lanceolata Nutrition 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000012166 beeswax Substances 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 238000003889 chemical engineering Methods 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 235000019388 lanolin Nutrition 0.000 abstract 1
- 229940039717 lanolin Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 description 5
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- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 1
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Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention belongs to the technical field of medicine chemical engineering, and particularly relates to a medicine for treating chilblain, which is characterized by comprising the following raw materials in parts by weight: 3-5 parts of iodine, 3-5 parts of potassium iodide, 8-12 parts of glycerol, 4-6 parts of lanolin, 4-8 parts of beeswax, 50-70 parts of vaseline, 1.5-5.5 parts of borneol, 0.5-1.5 parts of eugenol, 4-6 parts of methyl salicylate and 1-3 parts of sheep horn powder or ox horn powder or buckhorn powder with the fineness of less than 150 meshes. The invention also discloses a manufacturing method of the medicine for treating chilblain. The invention mainly has the advantages of simple manufacturing process, long storage time, short treatment time and low treatment cost, and is fragrant.
Description
Technical field
The invention belongs to pharmaceutical chemistry technical field, especially relate to a kind of medicine for the treatment of chilblain and preparation method thereof.
Background technology
Chilblain is more common in the low and humid region comparatively of winter temperature: good sending out located in hands, foot, auricle and nose etc.Mainly be exposed to low temperature environment repeatedly and protect relatively poor relevant with the sick position of decreasing.Finding expression in the part has the skin purple red color spot of gargalesthesia or distending pain, pimple or tuberosity pathological changes, can accompany edema and water cellulitis.Course of disease mesocuticle is tear-away, and is hemorrhage, rotten to the corn or ulcer occurs, finally forms paralysed trace or fibrosis.Chilblain easily recurs, and reduces relevant with chronic vasculitis inflammatory and the skin resistance of ill back local skin.The medicine of existing treatment chilblain is few and therapeutic effect is good inadequately, and treatment time is long, and the medical expense height uses inconvenient.
Domestic research for the chilblain medicine has for many years and a large amount of achievements in research is arranged, and as the patent No. be: 200710168576.9, denomination of invention is: a kind of medicine for external use of anti-treating chilblain; As sharp number be: 201110265936.3, denomination of invention is: anti-chilblain Adeps Serpentis liniment; And for example the patent No. is: 200810123744.7, denomination of invention is: a kind of medicine for the treatment of chilblain; Be for sharp number for another example: 201210013689.2, denomination of invention is: a kind of Chinese medicine for the treatment of chilblain; Etc. patent of invention, all studied the medicine for the treatment of chilblain, but effect is all undesirable, for this reason, society demanded urgently treatment speed faster medicine occur.
Summary of the invention
For addressing the above problem, the objective of the invention is to disclose a kind of medicine for the treatment of chilblain, it has effects such as treatment short treating period, medical expense are low; Further, the present invention also discloses its manufacture method, and the present invention realizes by the following technical solutions.
A kind of medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
In first embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts.
In second embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part.
In the 3rd embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts.
The medicine for the treatment of chilblain described above, wherein said Cornu Caprae seu Ovis powder are the powder that the angle of goat or sheep or tail feather sheep is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; The powder that described harts horn carbon is pulverized and formed after grinding for the angle of cover deer or Cervus nippon Temminck.
The medicine of above-mentioned treatment chilblain, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange flavor essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
The medicine of above-mentioned treatment chilblain, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
The medicine of above-mentioned treatment chilblain, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
Using method of the present invention: the present invention is coated in the chilblain position, and per 12～13 hours once, applies at least continuously 8 times, for rotten position, must not contact tap water during the coating.
The present invention have make simple, long shelf-life, advantage such as treatment time is short, medicine of the present invention has fragrance, does not have uncomfortable sensation and untoward reaction during the patient applies; The present invention has long-time drug effect retention, applies number of times still less, and the patient cures more convenient and quick.
Therefore, the present invention has following main beneficial effect: make simple, long shelf-life, treatment time is short, have fragrance, the treatment cost is low.
The specific embodiment
Embodiment 1
A kind of medicine for the treatment of chilblain, by weight, it includes following each raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts; The medicine of described treatment chilblain, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: test for 160 patients, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; The men and women half and half in each age bracket.(Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314) judge chilblain according to " combination of Chinese and Western medicine dermatological " the 2nd edition.Have half to fester in each age bracket, and the number men and women of festering equate; Through clinical use, apply 10 times after, the whole rehabilitations of the personnel of not festering; After applying 16 times, the philtrum that festers has 80% rehabilitation; After applying 20 times, all rehabilitations; Therefore, present embodiment has better therapeutic effect.
Embodiment 2
A kind of medicine for the treatment of chilblain, by weight, it includes following each raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part; The medicine of described treatment chilblain, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: test for 160 patients, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; The men and women half and half in each age bracket.(Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314) judge chilblain according to " combination of Chinese and Western medicine dermatological " the 2nd edition.Have half to fester in each age bracket, and the number men and women of festering equate; Through clinical use, apply 12 times after, the whole rehabilitations of the personnel of not festering; After applying 16 times, the philtrum that festers has 70% rehabilitation; After applying 22 times, all rehabilitations; Therefore, present embodiment has better therapeutic effect.
Embodiment 3
A kind of medicine for the treatment of chilblain, by weight, it includes following each raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts; The medicine of described treatment chilblain, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: test for 160 patients, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; The men and women half and half in each age bracket.(Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314) judge chilblain according to " combination of Chinese and Western medicine dermatological " the 2nd edition.Have half to fester in each age bracket, and the number men and women of festering equate; Through clinical use, apply 8 times after, the whole rehabilitations of the personnel of not festering; After applying 14 times, the philtrum that festers has 90% rehabilitation; After applying 18 times, all rehabilitations; Therefore, present embodiment has better therapeutic effect.
The medicine of the treatment chilblain described in above-mentioned arbitrary embodiment, wherein said Cornu Caprae seu Ovis powder are the powder that the angle of goat or sheep or tail feather sheep is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; The powder that described harts horn carbon is pulverized and formed after grinding for the angle of cover deer or Cervus nippon Temminck.
Repetition test through the applicant, and clinical practice, find to adopt the medicine of following prescription, can both reach the application's purpose: a kind of medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
Above-mentioned prescription is by following clinical trial: test for 160 patients, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; The men and women half and half in each age bracket.(Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314) judge chilblain according to " combination of Chinese and Western medicine dermatological " the 2nd edition.Through clinical use, apply 24 times after the whole rehabilitations of all personnel; Therefore, medicine of the present invention has better therapeutic effect.
Certainly, the medicine of the treatment chilblain described in above-mentioned arbitrary embodiment, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange flavor essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
Certainly, the medicine of the treatment chilblain when having essence, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
Using method of the present invention: the present invention is coated in the chilblain position, and per 12～13 hours once, applies at least continuously 6 times, for rotten position, must not contact tap water during the coating.
The present invention have make simple, long shelf-life, advantage such as treatment time is short, medicine of the present invention has fragrance, does not have uncomfortable sensation and untoward reaction during the patient applies; The present invention has long-time drug effect retention, applies number of times still less, and the patient cures more convenient and quick.
Therefore, the present invention has following main beneficial effect: make simple, long shelf-life, treatment time is short, have fragrance, the treatment cost is low.
The present invention is not limited to above-mentioned preferred forms, should be appreciated that design of the present invention can be by other various forms enforcement utilizations, and they drop in protection scope of the present invention equally.
Claims (10)
1. medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
2. medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts.
3. medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part.
4. medicine for the treatment of chilblain, it is characterized in that by weight it includes following each raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts.
5. according to the medicine of claim 1 to described any one treatment chilblain of claim 4, it is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or tail feather sheep and the powder that forms after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; The powder that described harts horn carbon is pulverized and formed after grinding for the angle of cover deer or Cervus nippon Temminck.
6. according to the medicine of claim 1 to described any one treatment chilblain of claim 4, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange flavor essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
7. according to the medicine of claim 1 to described any one treatment chilblain of claim 4, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
8. the manufacture method of the medicine for the treatment of chilblain according to claim 7 is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or tail feather sheep and the powder that forms after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; The powder that described harts horn carbon is pulverized and formed after grinding for the angle of cover deer or Cervus nippon Temminck.
9. according to the medicine of the described treatment chilblain of claim 6, it is characterized in that it makes by the following method: (1) takes by weighing each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and constantly be stirred to condensation, obtain base material mixture; (3) get potassium iodide, fineness less than 150 purpose Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, adds glycerol and grinds and make the potassium iodide dissolving, adds iodine and grinds and make its dissolving, adds lanoline and grinds well, and obtains medicinal mixture; (4) base material mixture is joined in the medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
10. the manufacture method of the medicine for the treatment of chilblain according to claim 9 is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or tail feather sheep and the powder that forms after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; The powder that described harts horn carbon is pulverized and formed after grinding for the angle of cover deer or Cervus nippon Temminck.
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| CN201310267521.9A CN103285034B (en) | 2013-07-01 | 2013-07-01 | Medicine for treating chilblain and manufacturing method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067817A (en) * | 1992-05-09 | 1993-01-13 | 朱乃军 | Chilblain spirit ointment, cream and preparation technology thereof |
| CN1204512A (en) * | 1998-07-15 | 1999-01-13 | 湖南省劳动卫生职业病防治研究所 | Medicine for prevention and cure of chilblain |
| CN1977849A (en) * | 2005-12-02 | 2007-06-13 | 天津市世雄科技发展有限公司 | Kibe ointment with bactericidal-bacteriostasis function |
| CN102764417A (en) * | 2012-07-03 | 2012-11-07 | 夏义深 | Chinese materia medica frostbite cream |
-
2013
- 2013-07-01 CN CN201310267521.9A patent/CN103285034B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067817A (en) * | 1992-05-09 | 1993-01-13 | 朱乃军 | Chilblain spirit ointment, cream and preparation technology thereof |
| CN1204512A (en) * | 1998-07-15 | 1999-01-13 | 湖南省劳动卫生职业病防治研究所 | Medicine for prevention and cure of chilblain |
| CN1977849A (en) * | 2005-12-02 | 2007-06-13 | 天津市世雄科技发展有限公司 | Kibe ointment with bactericidal-bacteriostasis function |
| CN102764417A (en) * | 2012-07-03 | 2012-11-07 | 夏义深 | Chinese materia medica frostbite cream |
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| CN103285034B (en) | 2014-07-23 |
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