CN103272184A - Preparation for treating hyperthyreosis - Google Patents
Preparation for treating hyperthyreosis Download PDFInfo
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- CN103272184A CN103272184A CN2013102360365A CN201310236036A CN103272184A CN 103272184 A CN103272184 A CN 103272184A CN 2013102360365 A CN2013102360365 A CN 2013102360365A CN 201310236036 A CN201310236036 A CN 201310236036A CN 103272184 A CN103272184 A CN 103272184A
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Abstract
The invention relates to a preparation for treating hyperthyreosis. The preparation comprises substances in percentage by weight as follows: prunella vulgaris, manis pentadactyla, concha meretricis seu cyclinae, marine algae, kelp, platycodon grandiflorum, radix scrophulariae, agilawood, unprocessed rehmannia roots, oysters, concha haliotidis, rhizoma sparganii, curcuma zedoary, tuber fleeceflower stems, astragalus membranaceus, muskroot-like semiaquilegia roots, radix bupleuri and air potatoes. The preparation for treating the hyperthyreosis has the characteristics that the preparation is low in cost, easy to prepare, insignificant in toxic and side effects and remarkable in curative effect.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicament for the treatment of hyperthyroidism.
Background technology
Hyperthyroidism is that thyroid morbid state is secreted due to the excess thyroid hormone.Because thyroid secretion is subjected to the adjusting of hypothalamic-pituitary-thyroid axis, past attempts thinks that hyperthyroidism is because the TSH of pituitary supersecretion stimulates due to thyroid hyperplasia and the secretion.Studies show that the pituicyte of hyperthyroid patient generation TSH is hypertrophy not, but atrophy; Low and the HPX patient of pituitary function still has hyperthyroidism to take place.To hyperthyroid patient injection throtropin releasing hormone (TRH) TSH is raise, the thyroid that hyperthyroid patient be described also not exclusively is subjected to the control of hypothalamus-pituitary system.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of hyperthyroidism.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of hyperthyroidism, it comprises following materials by weight: Spica Prunellae 10-20 part, Squama Manis 5-20 part, Concha Meretricis seu Cyclinae 10-30 part, Sargassum 5-20 part, Thallus Laminariae (Thallus Eckloniae) 5-20 part, Radix Platycodonis 10-20 part, Radix Scrophulariae 10-30 part, Lignum Aquilariae Resinatum 5-20 part, Radix Rehmanniae 10-30 part, Concha Ostreae 10-30 part, Concha Haliotidis 10-20 part, rhizoma sparganic 5-20 part, Rhizoma Curcumae 5-20 part, Caulis Polygoni Multiflori 10-20 part, Radix Astragali 10-20 part, Radix Semiaquilegiae 5-20 part, Radix Bupleuri 10-20 part and Rhizoma Dioscoreae Bulbiferae 10-20 part.
Preferably, the medicament for the treatment of hyperthyroidism of the present invention comprises following materials by weight: 15 parts of 15 parts of Spica Prunellaes, 10 parts of Squama Maniss, 20 parts of Concha Meretricis seu Cyclinaes, 10 parts of Sargassums, 10 parts of Thallus Laminariae (Thallus Eckloniae)s, 15 parts of Radix Platycodoniss, 20 parts of Radix Scrophulariaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts in the Radix Rehmanniae, 20 parts of Concha Ostreaes, 15 parts of Concha Haliotidis, 10 parts of rhizoma sparganic, 10 parts of Rhizoma Curcumae, 15 parts of Caulis Polygoni Multiflori, 15 parts of the Radixs Astragali, 10 parts of Radix Semiaquilegiaes, 15 parts of Radix Bupleuri and Rhizoma Dioscoreae Bulbiferaes.
More preferably, the medicament for the treatment of hyperthyroidism of the present invention also comprises following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
More preferably, described medicament can be tablet, dispersible tablet, powder or capsule.
As used herein,
Rhizoma Dioscoreae Bulbiferae
Chinese medicine formal name used at school: Rhizoma Dioscoreae bulbiferae.
(English) Air Pootalo Yam Rhizome
Base is former: these product are the tuber of monocotyledon Dioscoreaceae Dioscoreaceae Dioscorea bulbifera L. DioscoreabulbiferaL..
[source form] Bulbilus dioscoreae: the yellowish-brown bulbil at axil place, about 1 centimetre of diameter.
[meridian distribution of property and flavor] is bitter, hot, cold.
Concha Meretricis seu Cyclinae
(" decoction pieces is newly joined ")
[source] is the shell of several sea clams such as Veneridae animal Concha Meretricis Seu Cyclinae.
2 in [zoomorphism] Concha Meretricis Seu Cyclinae shell, subcircular.Shell is about 36.5～56 millimeters, high several and appearance etc., and width is about 2/3 of length.The shell rostellum goes out, and is positioned at dorsal part central authorities, and the tip is forwards crooked.No lunule ， Parapet face is long and narrow, all is that ligament is occupied, ligament yellowish-brown, not outstanding shell face.The shell surface utmost point protrudes, and growth line is fine and closely woven the top person, and is very not remarkable, gradually thick to the outside of belly, protrudes the shell face.Faint yellow or the brownish red of shell face.The shell inner face is white or light yellowish pink, and the edge has neat little tooth.The nearer back of the body edge of little tooth is bigger.Hinge is long and narrow and flat, 3 main teeth of each tool of left and right shell.The overcoat trace is obvious, and pallial sinus is dark, tiltedly extends the central part of shell upward from ventral margin, and the rear end is wide, and is gradually narrow to front end, is wedge shape.The anterior adductor muscle trace is elongated, is the first quarter moon shape, and the posterior adductor muscle trace is big, ellipse.Foot is flat, ligule.Move in the argillo arenaceous seabed in coastal waters.Coastal area of china all has distribution.
[collection] caught between 4～October.Obtain the back fleshing, clean and dry.
[medical material] shell is similar round, the outer surface yellow-white.Shell top is askew to a side, arranges concentricity closely, along this stricture of vagina or there are several dusty blue to take turns stricture of vagina, ventral margin serration shape.The milky white of shell inner face or Bluish white, smooth no stricture of vagina.Body is light, and matter is hard slightly crisp, and the section laminated striation is not obvious.Gas is raw meat slightly, and is lightly seasoned.Be good with smooth, clean person.Ground such as main product Jiangsu, Zhejiang, Shandong, Fujian.Now use the medical material Concha Meretricis seu Cyclinae, except above-mentioned a kind of, the shell of equal animal Conch Meretricis seu Cyclinae is still arranged, also use on an equal basis.
[nature and flavor] are salty, and are flat.
[return through] goes into brothers' sun, Yangming Channel.Go into the heart, kidney two warps.
[function cures mainly] heat clearing away, diuretic reduces phlegm, softening the hard mass.Control heat-phlegm and breathe heavily and cough, edema, gonorrhea, wart, tumor are gathered, blood agglomeration chest pain, dysentery, hemorrhoid, metrorrhagia, leukorrhagia.
The medicament for the treatment of hyperthyroidism of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
The specific embodiment
Embodiment 1:
Take by weighing Spica Prunellae 150 grams, Squama Manis 100 grams, Concha Meretricis seu Cyclinae 200 grams, Sargassum 100 grams, Thallus Laminariae (Thallus Eckloniae) 100 grams, Radix Platycodonis 150 grams, Radix Scrophulariae 200 grams, Lignum Aquilariae Resinatum 100 grams, the Radix Rehmanniae 200 grams, Concha Ostreae 200 grams, Concha Haliotidis 150 grams, rhizoma sparganic 100 grams, Rhizoma Curcumae 100 grams, Caulis Polygoni Multiflori 150 grams, the Radix Astragali 150 grams, Radix Semiaquilegiae 100 grams, Radix Bupleuri 150 grams and Rhizoma Dioscoreae Bulbiferae 150 grams, pulverize, add lactose 250 grams, mix, cross 80 mesh sieves, divide to install in 100 bags, namely get powder of the present invention.
Embodiment 2:
Take by weighing Spica Prunellae 150 grams, Squama Manis 100 grams, Concha Meretricis seu Cyclinae 200 grams, Sargassum 100 grams, Thallus Laminariae (Thallus Eckloniae) 100 grams, Radix Platycodonis 150 grams, Radix Scrophulariae 200 grams, Lignum Aquilariae Resinatum 100 grams, the Radix Rehmanniae 200 grams, Concha Ostreae 200 grams, Concha Haliotidis 150 grams, rhizoma sparganic 100 grams, Rhizoma Curcumae 100 grams, Caulis Polygoni Multiflori 150 grams, the Radix Astragali 150 grams, Radix Semiaquilegiae 100 grams, Radix Bupleuri 150 grams, Rhizoma Dioscoreae Bulbiferae 150 grams, Fructus Broussonetiae 50 grams, RADIX PEUCEDANI 30 gram Herba Thlaspiss 60 grams, Rhizoma Smilacis Chinensis 50 grams, Herba Cichorii 70 gram Rhizoma Dioscoreae Septemlobaes 40 gram Herba Siegesbeckiaes 60 grams, Herba Gendarussae 30 grams, Cortex Syingae Amurensis 50 grams, Herba pterocephali 30 grams, Nodus Nelumbinis Rhizomatis 30 grams, Medulla Stachyuri (Medulla Helwingiae) 70 grams, Flos Bombacis Malabarici 40 grams, Concha Arcae 50 grams, Caulis Mahoniae 30 grams, Folium Sauropi 60 grams, Semen Lablab Album 70 grams, Retinervus Luffae Fructus 30 grams, Herba Polygoni cymosi 50 grams, Semen Celosiae 30 grams and Fructus Litseae 50 grams, pulverize, add lactose 450 grams, mix, cross 80 mesh sieves, divide to install in 100 bags, namely get powder of the present invention.
Experimental example
Case is selected
100 examples all meet the hyperthyroidism diagnostic criteria.Man's 50 examples, women 50 examples, age 20-40 year 41 examples, 41-60 year 43 examples,＞60 years old 16 example, the course of disease 15 days-1 year, average 21 months.Be divided into two groups, every group of 50 routine patients, two groups of there was no significant differences (P＞0.05) in side such as sex, age, the course of disease, state of an illness scoring and relatively have comparability.
Diagnostic criteria
1. hyperthyroidism classical symptom: being irritable and irascible, To Be Protected from Heat hyperhidrosis, limbs are weak, cardiopalmus, receive that high easy famine, extremity are trembled, ophthalmic bloated, times of defecation are many, menoxenia etc., tool is wherein more than 6; 2. hyperthyroidism typical case sign is arranged: exophthalmos, widening of palpebral fissure, thyromegaly, trembling of limbs, lose weight, tachycardia, systolic pressure increase, pulse pressure difference increase etc., in specifically levying more than 4; 3. lab testing: serum T 3, T4 exceed normal value (T31.2-3.4mmol/L, T
454-174mmol/L); Or the iodine uptake rate increases peak reach person.
The powder of first group of oral embodiment 1 preparation of patient, every day twice, each oral 2 bags, treating 30 days is 1 course for the treatment of, treats 3 courses for the treatment of.
The powder of second group of oral embodiment 2 preparation of patient, every day twice, each oral 2 bags, treating 30 days is 1 course for the treatment of, treats 3 courses for the treatment of.
Criterion of therapeutical effect
Clinical recovery: subjective symptoms disappears, and sign disappears substantially, and it is normal that lab testing recovers; Produce effects: main clinic symptoms disappears, and sign is clearly better, and thyroid function is down to 1 times that normally or is not higher than normal value; Take a turn for the better: sings and symptoms takes a turn for the better or most of the improvement, and thyroid function descends more than 50% or T
3, T
4A decline is arranged; Invalid: treatment back sings and symptoms does not have and is clearly better, or slightly improves, but the check serum T
3, T
4Be worth no significant change.
Therapeutic outcome
Among first group of patient, clinical recovery 25 examples, produce effects 17 examples, 8 examples take a turn for the better; Among second group of patient, clinical recovery 40 examples, produce effects 8 examples, 2 examples take a turn for the better.Do not occur serious adverse reaction in the observation, blood, urine, stool routine and hepatic and renal function inspection that treatment finishes the two groups of patients in back there is no unusually.
Claims (4)
1. a medicament for the treatment of hyperthyroidism is characterized in that it comprises following materials by weight: Spica Prunellae 10-20 part, Squama Manis 5-20 part, Concha Meretricis seu Cyclinae 10-30 part, Sargassum 5-20 part, Thallus Laminariae (Thallus Eckloniae) 5-20 part, Radix Platycodonis 10-20 part, Radix Scrophulariae 10-30 part, Lignum Aquilariae Resinatum 5-20 part, Radix Rehmanniae 10-30 part, Concha Ostreae 10-30 part, Concha Haliotidis 10-20 part, rhizoma sparganic 5-20 part, Rhizoma Curcumae 5-20 part, Caulis Polygoni Multiflori 10-20 part, Radix Astragali 10-20 part, Radix Semiaquilegiae 5-20 part, Radix Bupleuri 10-20 part and Rhizoma Dioscoreae Bulbiferae 10-20 part.
2. the medicament for the treatment of hyperthyroidism according to claim 1 is characterized in that it comprises following materials by weight: 15 parts of 15 parts of Spica Prunellaes, 10 parts of Squama Maniss, 20 parts of Concha Meretricis seu Cyclinaes, 10 parts of Sargassums, 10 parts of Thallus Laminariae (Thallus Eckloniae)s, 15 parts of Radix Platycodoniss, 20 parts of Radix Scrophulariaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts in the Radix Rehmanniae, 20 parts of Concha Ostreaes, 15 parts of Concha Haliotidis, 10 parts of rhizoma sparganic, 10 parts of Rhizoma Curcumae, 15 parts of Caulis Polygoni Multiflori, 15 parts of the Radixs Astragali, 10 parts of Radix Semiaquilegiaes, 15 parts of Radix Bupleuri and Rhizoma Dioscoreae Bulbiferaes.
3. the medicament for the treatment of hyperthyroidism according to claim 1 and 2 is characterized in that also comprising following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
4. according to the medicament of each described treatment hyperthyroidism in the claim 1 to 3, it is characterized in that described medicament can be tablet, dispersible tablet, powder or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310236036.5A CN103272184B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating hyperthyreosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310236036.5A CN103272184B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating hyperthyreosis |
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| Publication Number | Publication Date |
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| CN103272184A true CN103272184A (en) | 2013-09-04 |
| CN103272184B CN103272184B (en) | 2014-09-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310236036.5A Expired - Fee Related CN103272184B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating hyperthyreosis |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103948824A (en) * | 2014-04-30 | 2014-07-30 | 郭如英 | Chinese medicinal composition for treating hyperthyroidism and preparation method thereof |
| CN104547568A (en) * | 2014-12-25 | 2015-04-29 | 韦邦力 | Traditional Chinese medicine for treating hyperthyroidism |
| CN105168530A (en) * | 2015-10-29 | 2015-12-23 | 张冬 | Traditional Chinese medicine for treating thyroiditis and preparing method thereof |
| CN105362633A (en) * | 2014-08-21 | 2016-03-02 | 李新民 | Formula for treating hyperthyroidism |
| CN106109899A (en) * | 2016-08-08 | 2016-11-16 | 姜晓红 | A kind of Chinese medicine composition for hyperthyroidism |
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| CN1485083A (en) * | 2003-06-13 | 2004-03-31 | 许新琳 | Capsule for thyroid cancer / tumor and lymph node |
| CN102335403A (en) * | 2011-10-09 | 2012-02-01 | 许俊斋 | Medicine for treating thyroid cancer and malignant adenolymphoma |
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2013
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1485083A (en) * | 2003-06-13 | 2004-03-31 | 许新琳 | Capsule for thyroid cancer / tumor and lymph node |
| CN102335403A (en) * | 2011-10-09 | 2012-02-01 | 许俊斋 | Medicine for treating thyroid cancer and malignant adenolymphoma |
Non-Patent Citations (3)
| Title |
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| 任志雄，李光善，倪青: "林兰论治桥本甲状腺炎的学术思想", 《辽宁中医杂志》 * |
| 刘喜明,张奋,吴欣芳: ""痰"在甲状腺肿大发病中的作用及化痰散结法的临床应用", 《河南中医》 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103948824A (en) * | 2014-04-30 | 2014-07-30 | 郭如英 | Chinese medicinal composition for treating hyperthyroidism and preparation method thereof |
| CN105362633A (en) * | 2014-08-21 | 2016-03-02 | 李新民 | Formula for treating hyperthyroidism |
| CN104547568A (en) * | 2014-12-25 | 2015-04-29 | 韦邦力 | Traditional Chinese medicine for treating hyperthyroidism |
| CN105168530A (en) * | 2015-10-29 | 2015-12-23 | 张冬 | Traditional Chinese medicine for treating thyroiditis and preparing method thereof |
| CN106109899A (en) * | 2016-08-08 | 2016-11-16 | 姜晓红 | A kind of Chinese medicine composition for hyperthyroidism |
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| Publication number | Publication date |
|---|---|
| CN103272184B (en) | 2014-09-03 |
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