CN103272047A - Infantile cold granules and preparation method thereof - Google Patents

Infantile cold granules and preparation method thereof Download PDF

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Publication number
CN103272047A
CN103272047A CN 201310179361 CN201310179361A CN103272047A CN 103272047 A CN103272047 A CN 103272047A CN 201310179361 CN201310179361 CN 201310179361 CN 201310179361 A CN201310179361 A CN 201310179361A CN 103272047 A CN103272047 A CN 103272047A
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parts
radix
filter
preparation
keep
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Chinese (zh)
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陆玉萍
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Abstract

The invention discloses infantile cold granules which consist of the following raw materials: 65-70 parts of pogostemon cablin, 70-80 parts of fructus forsythiae, 75-78 parts of radix cynanchi atrati, 60-65 parts of rhizoma rehmanniae, 90-95 parts of gypsum, 8-10 parts of folium isatidis, 10-15 parts of folium mori, 30-40 parts of cortex phellodendri and 0-60 parts of radix puerariae. The invention also discloses a preparation method of the infantile cold granules. The infantile cold granules and the preparation method thereof disclosed by the invention have the advantages that a small dosage of the cold medicine is applied, the effect is obvious, and a little side effect is caused; the preparation technology has mild conditions and is fine; and with good stability and small dosage, the infantile cold granules are suitable for infants.

Description

A kind of xiao'er ganmao granules and preparation method thereof
Technical field
The present invention relates to a kind of xiao'er ganmao granules.
The invention still further relates to a kind of preparation method of xiao'er ganmao granules.
Background technology
Common cold pill is made up of Herba Ephedrae, Herba Menthae, Gypsum Fibrosum, Folium Perillae, Semen Armeniacae Amarum, Radix Peucedani, Flos Lonicerae, Flos Chrysanthemi, Radix Scutellariae, Radix Glycyrrhizae, Radix Platycodonis, Folium Mori, and function cures mainly: clearing and antitussive, depressed lung-energy dispersing.Be used for flu, have a headache and fever, rhinorrhea with clear discharge, it is low voice speaking to cough, the QI rising in reverse order dyspnea with rapid respiration.Prove that through long-term clinical practice common cold pill is to the above-mentioned symptom determined curative effect.Not only dosage is big for common cold pill, drug absorption is slow, and patient's acceptance level is poor, is able to eat a week sometimes and does not all feel any better, and for children's, long-term prescription can produce bigger side effect.Therefore, need provide a kind of new technical scheme to solve the problems referred to above.
Summary of the invention
The purpose of this invention is to provide a kind of xiao'er ganmao granules, curative effect is fast, and side effect is little.
The technical solution used in the present invention:
A kind of xiao'er ganmao granules, formed by the raw material of following weight portion:
Herba Pogostemonis 65-70 part;
Fructus Forsythiae 70-80 part;
Radix Cynanchi Atrati 75-78 part;
Radix Rehmanniae 60-65 part;
Gypsum Fibrosum 90-95 part;
Folium Isatidis 8-10 part;
Folium Mori 10-15 part;
Cortex Phellodendri 30-40 part;
Radix Puerariae 50-60 part.
A kind of preparation method of xiao'er ganmao granules may further comprise the steps: press the recipe ratio of above-mentioned raw materials, get Herba Pogostemonis and Fructus Forsythiae and carry out steam distillation, collect volatile oil, keep filter liquor; The Gypsum Fibrosum sterilization is pulverized, and gets Gypsum Fibrosum powder; Radix Cynanchi Atrati, Radix Rehmanniae, Cortex Phellodendri, Radix Puerariae four Chinese medicine decoct with water, and decoct 3-4 hour, merge decoction liquor, filter, and keep decoction liquor; Folium Isatidis and the hot dipping of Folium Mori two flavor medicine elder generations 2 times merge hot dipping liquid, filter, and keep filtrate; Filter liquor, decoction liquor and filtrate are merged, carry out concentrating under reduced pressure, get extractum, spray into volatile oil in extractum, mixed 10-30 minute, granulation, drying get final product.
Advantage of the present invention is: coldrex of the present invention, and consumption is light, and effect is obvious, and side effect is little, the preparation process condition gentleness, sophisticated technologies have good stability, and dosage is few, is fit to children's and uses.
The specific embodiment
Following embodiment only is used for explanation the present invention, but can not limit protection scope of the present invention.
Embodiment 1
A kind of xiao'er ganmao granules, formed by following raw material:
Herba Pogostemonis 65 ㎏;
Fructus Forsythiae 70 ㎏;
Radix Cynanchi Atrati 75 ㎏;
Radix Rehmanniae 60 ㎏;
Gypsum Fibrosum 90 ㎏;
Folium Isatidis 8 ㎏;
Folium Mori 10 ㎏;
Cortex Phellodendri 30 ㎏;
Radix Puerariae 50 ㎏.
A kind of preparation method of xiao'er ganmao granules may further comprise the steps: press the recipe ratio of above-mentioned raw materials, get Herba Pogostemonis and Fructus Forsythiae and carry out steam distillation, collect volatile oil, keep filter liquor; The Gypsum Fibrosum sterilization is pulverized, and gets Gypsum Fibrosum powder; Radix Cynanchi Atrati, Radix Rehmanniae, Cortex Phellodendri, Radix Puerariae four Chinese medicine decoct with water, and decoct 3 hours, merge decoction liquor, filter, and keep decoction liquor; Folium Isatidis and the hot dipping of Folium Mori two flavor medicine elder generations 2 times merge hot dipping liquid, filter, and keep filtrate; Filter liquor, decoction liquor and filtrate are merged, carry out concentrating under reduced pressure, get extractum, spray into volatile oil in extractum, mixed 10 minutes, granulation, drying get final product.
Embodiment 2
A kind of xiao'er ganmao granules, formed by following raw material:
Herba Pogostemonis 68 ㎏;
Fructus Forsythiae 75 ㎏;
Radix Cynanchi Atrati 77 ㎏;
Radix Rehmanniae 63 ㎏;
Gypsum Fibrosum 93 ㎏;
Folium Isatidis 9 ㎏;
Folium Mori 12 ㎏;
Cortex Phellodendri 35 ㎏;
Radix Puerariae 55 ㎏.
A kind of preparation method of xiao'er ganmao granules may further comprise the steps: press the recipe ratio of above-mentioned raw materials, get Herba Pogostemonis and Fructus Forsythiae and carry out steam distillation, collect volatile oil, keep filter liquor; The Gypsum Fibrosum sterilization is pulverized, and gets Gypsum Fibrosum powder; Radix Cynanchi Atrati, Radix Rehmanniae, Cortex Phellodendri, Radix Puerariae four Chinese medicine decoct with water, and decoct 3.5 hours, merge decoction liquor, filter, and keep decoction liquor; Folium Isatidis and the hot dipping of Folium Mori two flavor medicine elder generations 2 times merge hot dipping liquid, filter, and keep filtrate; Filter liquor, decoction liquor and filtrate are merged, carry out concentrating under reduced pressure, get extractum, spray into volatile oil in extractum, mixed 20 minutes, granulation, drying get final product.
Embodiment 3
A kind of xiao'er ganmao granules, formed by following raw material:
Herba Pogostemonis 70 ㎏;
Fructus Forsythiae 80 ㎏;
Radix Cynanchi Atrati 78 ㎏;
Radix Rehmanniae 65 ㎏;
Gypsum Fibrosum 95 ㎏;
Folium Isatidis 10 ㎏;
Folium Mori 15 ㎏;
Cortex Phellodendri 40 ㎏;
Radix Puerariae 60 ㎏.
A kind of preparation method of xiao'er ganmao granules may further comprise the steps: press the recipe ratio of above-mentioned raw materials, get Herba Pogostemonis and Fructus Forsythiae and carry out steam distillation, collect volatile oil, keep filter liquor; The Gypsum Fibrosum sterilization is pulverized, and gets Gypsum Fibrosum powder; Radix Cynanchi Atrati, Radix Rehmanniae, Cortex Phellodendri, Radix Puerariae four Chinese medicine decoct with water, and decoct 4 hours, merge decoction liquor, filter, and keep decoction liquor; Folium Isatidis and the hot dipping of Folium Mori two flavor medicine elder generations 2 times merge hot dipping liquid, filter, and keep filtrate; Filter liquor, decoction liquor and filtrate are merged, carry out concentrating under reduced pressure, get extractum, spray into volatile oil in extractum, mixed 30 minutes, granulation, drying get final product.
Get 100 white mice, be divided into two groups, measure its body temperature, the fresh yeast normal saline of second day volume injected concentration 15% makes its heating, measures its body temperature afternoon, one group of coldrex of feeding is on the market fed a medicine morning then, feeds a medicine evening, another group is fed coldrex of the present invention, and medication was measured the body temperature of white mice after 2 days, feed the white mice of coldrex of the present invention, good than another group of temperature recovery illustrates coldrex of the present invention, and refrigeration function is obvious.
Coldrex of the present invention, consumption is light, and effect is obvious, and side effect is little, the preparation process condition gentleness, sophisticated technologies have good stability, and dosage is few, is fit to children's and uses.

Claims (2)

1. an xiao'er ganmao granules is characterized in that, is made up of the raw material of following weight portion:
Herba Pogostemonis 65-70 part;
Fructus Forsythiae 70-80 part;
Radix Cynanchi Atrati 75-78 part;
Radix Rehmanniae 60-65 part;
Gypsum Fibrosum 90-95 part;
Folium Isatidis 8-10 part;
Folium Mori 10-15 part;
Cortex Phellodendri 30-40 part;
Radix Puerariae 50-60 part.
2. the preparation method of an xiao'er ganmao granules is characterized in that, may further comprise the steps: by the said recipe ratio of claim 1, get Herba Pogostemonis and Fructus Forsythiae and carry out steam distillation, collect volatile oil, keep filter liquor; The Gypsum Fibrosum sterilization is pulverized, and gets Gypsum Fibrosum powder; Radix Cynanchi Atrati, Radix Rehmanniae, Cortex Phellodendri, Radix Puerariae four Chinese medicine decoct with water, and decoct 3-4 hour, merge decoction liquor, filter, and keep decoction liquor; Folium Isatidis and the hot dipping of Folium Mori two flavor medicine elder generations 2 times merge hot dipping liquid, filter, and keep filtrate; Filter liquor, decoction liquor and filtrate are merged, carry out concentrating under reduced pressure, get extractum, spray into volatile oil in extractum, mixed 10-30 minute, granulation, drying get final product.
CN 201310179361 2013-05-15 2013-05-15 Infantile cold granules and preparation method thereof Pending CN103272047A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201310179361 CN103272047A (en) 2013-05-15 2013-05-15 Infantile cold granules and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201310179361 CN103272047A (en) 2013-05-15 2013-05-15 Infantile cold granules and preparation method thereof

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CN103272047A true CN103272047A (en) 2013-09-04

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103919919A (en) * 2014-04-24 2014-07-16 张艳霞 Chinese herba preparation for treating cold, as well as preparation method thereof
CN107308275A (en) * 2017-08-07 2017-11-03 陕西必康制药集团控股有限公司 A kind of xiao'er ganmao granules and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103919919A (en) * 2014-04-24 2014-07-16 张艳霞 Chinese herba preparation for treating cold, as well as preparation method thereof
CN107308275A (en) * 2017-08-07 2017-11-03 陕西必康制药集团控股有限公司 A kind of xiao'er ganmao granules and preparation method thereof
CN107308275B (en) * 2017-08-07 2020-07-31 陕西必康制药集团控股有限公司 Infantile common cold granules and preparation method thereof

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Application publication date: 20130904