CN103271979A - Traditional Chinese medicine oral liquid for treating sheep coccidiosis and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid for treating sheep coccidiosis and preparation method thereof Download PDFInfo
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- CN103271979A CN103271979A CN 201310201152 CN201310201152A CN103271979A CN 103271979 A CN103271979 A CN 103271979A CN 201310201152 CN201310201152 CN 201310201152 CN 201310201152 A CN201310201152 A CN 201310201152A CN 103271979 A CN103271979 A CN 103271979A
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Abstract
The invention provides a traditional Chinese medicine oral liquid for treating sheep coccidiosis and a preparation method thereof. The traditional Chinese medicine oral liquid comprises the following components in parts by weight: 4-6 parts of stone-like omphalia, 3-5 parts of common carpesium fruit, 1-2 parts of Chinese torreya and 1-2 parts of liquorice. The traditional Chinese medicine oral liquid is prepared by a decocting method. The traditional Chinese medicine oral liquid with reasonable components of traditional Chinese medicines has the remarkable effect of dispelling coccidium. An effective curative medicine for treating sheep coccidiosis is provided for the animal husbandry. The traditional Chinese medicine oral liquid has the characteristics of quick effect, exact curative effect, no medicine residue, difficulty in generating resistance to medicine and no toxic and side effects. The traditional Chinese medicine oral liquid is the first choice to treat sheep coccidiosis, is simple in preparation method, and is suitable for demands of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid and preparation method thereof, especially a kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis and preparation method thereof.
Background technology
The sheep coccidiosis is that the coccidiosis by Amy section Eimeria parasitizes the caused a kind of protozoacide in Intestinum caprae seu ovis road, is the common a kind of protozoon disease of goat.This disease is worldwide distribution, symptoms such as the morbidity sheep only presents diarrhea, becomes thin, anemia, dysplasia, and severe patient causes death, the main harm lamb.Clinical symptoms mainly show as disease just goat soft stool appears, excrement is shapeless, but spirit, appetite are normal.Begin dysentery after 3 one 5 days, to water sample, yellowish-brown or black are mixed with downright bad mucus, blood and a large amount of coccidian oocysts to feces by the medicated porridge sample, loss of appetite or useless exhausted, and thirsty desire increases.Down in spirits thereupon, disorderly thick by hair, become thin rapidly, visual mucosal pallor, body temperature is normal or high slightly, it is acute that the chronic course of disease reaches several weeks through about 1 week, severe infections die of exhaustion the then long term growth dysplasia of anti-mistake at last.Adult goat mostly is inapparent infection, clinically no abnormal performance; The kid M ﹠ M at 1-3 monthly age is higher, and it is shapeless or have loose bowels that its feature mainly shows as excrement, and appetite descends, retarded growth, and the height anemia dies of exhaustion and dies when serious.Therefore by Chinese medicine is rationally screened and prescription, the Chinese medicine preparation of developing treatment sheep coccidiosis has very important production practices meaning as the first-selection for the treatment of the sheep coccidiosis.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis.
Another technical problem to be solved by this invention is to provide the preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, by its parts by weight Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part.
Preferably, the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis is obtained by following method:
(1) taking by weighing Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part by weight is raw material;
(2) above-mentioned four Chinese medicine material is mixed the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is 1.10-1.15 that filtrate is concentrated into relative density, and it is standby to obtain concentrating clear paste under 70 ℃ of conditions;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.17-1.22, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Preferably, the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis is by its parts by weight Omphalia 4-5 part, Fructus Carpesii 4-5 part, Semen Torreyae 1.5-2 part, Radix Glycyrrhizae 1-1.5 part.
Preferably, the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis is by 4 parts of its parts by weight Omphalias, 4 parts of Fructus Carpesiis, 2 parts of Semen Torreyaes, 1 part in Radix Glycyrrhizae.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) taking by weighing Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part by weight is raw material;
(2) above-mentioned four Chinese medicine material is mixed the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is 1.10-1.15 that filtrate is concentrated into relative density, and it is standby to obtain concentrating clear paste under 70 ℃ of conditions;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.17-1.22, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Preferably, the preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis adds 3 ‰ sodium benzoate in the prepared Chinese medicine oral liquid of step (3).
Reclaim ethanol in the preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, described step (3) and refer to by the method for high temperature evaporation ethanol is recycled to storage alcohol jar, but the utilization of ethanol secondary is reclaimed the back concentration of alcohol and remained on 80%-85%.
Above-mentioned relative density refers to the proportion of this supernatant.
The consumption of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis is for pressing the described Chinese medicine oral liquid of the sick sheep 10-20ml of per kilogram of body weight, and being used in conjunction 3-5 days is a course for the treatment of.
The invention has the beneficial effects as follows:
The Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, with the Chinese medicine reasonable formula, has the effect of driving coccidiosis significantly, for animal husbandry provides a kind of effective medicine for the treatment of the sheep coccidiosis, have instant effect, curative effect really, no drug residue, be difficult for producing drug resistance, characteristics without any side effects, be the first-selection for the treatment of sheep coccidiosis; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 4kg, Fructus Carpesii 4kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 4kg, Fructus Carpesii 4kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.13,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.20, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Embodiment 2
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 6kg, Fructus Carpesii 3kg, Semen Torreyae 1kg, Radix Glycyrrhizae 2kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 6kg, Fructus Carpesii 3kg, Semen Torreyae 1kg, Radix Glycyrrhizae 2kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.10,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.22, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Embodiment 3
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 4kg, Fructus Carpesii 5kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 4kg, Fructus Carpesii 5kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.15,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.17, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Embodiment 4
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 4kg, Fructus Carpesii 5kg, Semen Torreyae 1.5kg, Radix Glycyrrhizae 1.5kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 4kg, Fructus Carpesii 5kg, Semen Torreyae 1.5kg, Radix Glycyrrhizae 1.5kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.12,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.18, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Embodiment 5
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 5kg, Fructus Carpesii 4kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 5kg, Fructus Carpesii 4kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.14,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.21, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
Embodiment 6
A kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis is made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, wherein, and Omphalia 4.5kg, Fructus Carpesii 4.5kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1.2kg.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment sheep coccidiosis, concrete preparation process is as follows:
(1) take by weighing Omphalia 4.5kg, Fructus Carpesii 4.5kg, Semen Torreyae 2kg, Radix Glycyrrhizae 1.2kg are raw material;
(2) will be above-mentioned the four Chinese medicine material mix the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is that to obtain concentrating clear paste under 1.11,70 ℃ of conditions standby that filtrate is concentrated into relative density;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, filter, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.20, and cold preservation 48 hours filters, add 3 ‰ sodium benzoate in the filtrate, embedding, 100 ℃ of flowing steams 30 minutes, namely.
The described Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
Reclaiming ethanol described in one of embodiment 1-6 preparation method step (3) refers to by the method for high temperature evaporation ethanol is recycled in the storage alcohol jar.
The described Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid of the present invention is: Omphalia, Fructus Carpesii killing insect and eliminating accumulation in the side; The Semen Torreyae killing insect and eliminating accumulation, loosening bowel to relieve constipation, nourishing the lung to arrest cough; The Radix Glycyrrhizae relieving cough and asthma, coordinating the actions of various ingredients in a prescription.All medicines share, and Synergistic is remarkably productive to treatment sheep coccidiosis mutually, especially adopts embodiment 1 described proportioning, and the effect of driving coccidiosis strengthens greatly, particularly is fit to the control of sheep coccidiosis.
The clinical trial example:
The embodiment of the invention 1 described Chinese medicine oral liquid is carried out oral administration by the sick sheep 10-20ml of per kilogram of body weight, and being used in conjunction 3 days is a course for the treatment of.
In JIUYUE, 2012,50 2 monthly ages goat morbidities of Jinghai Yang Chang sickly just soft stool occurs, and excrement is shapeless, but spirit, appetite are normal.Begin dysentery after 3-5 days, to water sample, yellowish-brown or black are mixed with downright bad mucus, blood and a large amount of coccidian oocysts to feces by the medicated porridge sample, loss of appetite or useless exhausted, and thirsty desire increases.Be diagnosed as coccidiosis, gavage embodiment 1 described Chinese medicine oral liquid then, successive administration is after 3 days, and malaise symptoms disappears, and feces is shaped, and color is normal, and appetite and drinking-water are normal.
Above-mentioned detailed description of this a kind of Chinese medicine oral liquid for the treatment of the sheep coccidiosis and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (6)
1. a Chinese medicine oral liquid for the treatment of the sheep coccidiosis is characterized in that: be made up of Omphalia, Fructus Carpesii, Semen Torreyae and Radix Glycyrrhizae, by its parts by weight Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part.
2. the Chinese medicine oral liquid for the treatment of according to claim 1 sheep coccidiosis is characterized in that: obtained by following method:
(1) taking by weighing Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part by weight is raw material;
(2) above-mentioned four Chinese medicine material is mixed the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is 1.10-1.15 that filtrate is concentrated into relative density, and it is standby to obtain concentrating clear paste under 70 ℃ of conditions;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.17-1.22, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
3. the Chinese medicine oral liquid for the treatment of sheep coccidiosis according to claim 1 and 2 is characterized in that: by its parts by weight Omphalia 4-5 part, Fructus Carpesii 4-5 part, Semen Torreyae 1.5-2 part, Radix Glycyrrhizae 1-1.5 part.
4. the Chinese medicine oral liquid for the treatment of sheep coccidiosis according to claim 3 is characterized in that: by 4 parts of its parts by weight Omphalias, 4 parts of Fructus Carpesiis, 2 parts of Semen Torreyaes, 1 part in Radix Glycyrrhizae.
5. the preparation method of the Chinese medicine oral liquid of the described treatment of claim 1 sheep coccidiosis, it is characterized in that: concrete preparation process is as follows:
(1) taking by weighing Omphalia 4-6 part, Fructus Carpesii 3-5 part, Semen Torreyae 1-2 part, Radix Glycyrrhizae 1-2 part by weight is raw material;
(2) above-mentioned four Chinese medicine material is mixed the water that the back adds 10 times of amounts of medical material gross weight, decoct twice, decocted 2 hours at every turn, merge decocting liquid twice, filter, it is 1.10-1.15 that filtrate is concentrated into relative density, and it is standby to obtain concentrating clear paste under 70 ℃ of conditions;
(3) in the concentrated clear paste of step (2), add dehydrated alcohol to containing alcohol amount 70%(v/v), stir evenly, left standstill 12 hours, and filtered, reclaim ethanol and concentrated filtrate, adding water to relative density in the filtrate under 70 ℃ of conditions is 1.17-1.22, cold preservation 48 hours filters embedding, 100 ℃ of flowing steams 30 minutes, namely.
6. the preparation method of the Chinese medicine oral liquid for the treatment of sheep coccidiosis according to claim 5 is characterized in that: add 3 ‰ sodium benzoate in the prepared Chinese medicine oral liquid of step (3).
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474223A (en) * | 2014-12-01 | 2015-04-01 | 登封市博爱农林牧开发有限公司 | Traditional Chinese medicine preparation for preventing and treating coccidiosis in sheep and goat |
| CN105412725A (en) * | 2015-11-27 | 2016-03-23 | 全椒县马厂镇周巷山羊养殖场 | Feed additive for preventing and treating coccidiosis of sheep |
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2013
- 2013-05-27 CN CN 201310201152 patent/CN103271979A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474223A (en) * | 2014-12-01 | 2015-04-01 | 登封市博爱农林牧开发有限公司 | Traditional Chinese medicine preparation for preventing and treating coccidiosis in sheep and goat |
| CN105412725A (en) * | 2015-11-27 | 2016-03-23 | 全椒县马厂镇周巷山羊养殖场 | Feed additive for preventing and treating coccidiosis of sheep |
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