CN103271743A - Non-contact oxyhemoglobin saturation measuring device based on imaging device - Google Patents

Non-contact oxyhemoglobin saturation measuring device based on imaging device Download PDF

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Publication number
CN103271743A
CN103271743A CN2012105260877A CN201210526087A CN103271743A CN 103271743 A CN103271743 A CN 103271743A CN 2012105260877 A CN2012105260877 A CN 2012105260877A CN 201210526087 A CN201210526087 A CN 201210526087A CN 103271743 A CN103271743 A CN 103271743A
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China
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oxygen saturation
video
imaging device
saturation measurement
device based
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CN2012105260877A
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Inventor
赵京生
孔令琴
赵跃进
董立泉
刘明
刘小华
武红
李冰
简逸云
袁路彬
吴铁军
魏运亮
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No152 Central Hospital Of Chinese People's Liberation Army
Beijing Institute of Technology BIT
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No152 Central Hospital Of Chinese People's Liberation Army
Beijing Institute of Technology BIT
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Abstract

The invention discloses a non-contact oxyhemoglobin saturation measuring device based on an imaging device. The device is mainly used for measuring non-contact oxyhemoglobin saturation. The device is composed of a video collecting unit, a signal processing unit and an oxyhemoglobin saturation result displaying unit. The video collecting unit is composed of two CCDs and a video image collecting card which is connected with the CCDs through a data line, wherein the CCDs are located before the human face and are provided with optical filters with different wave sections. The signal processing unit is composed of a PC host machine or a high-speed signal processing circuit. The video information including the human face is collected through the video collecting unit and is transmitted to the PC host machine or the high-speed signal processing system through the data line to be processed in a data mode, pulse waves can be drawn by calculating the change of grey average, in a time domain, of the human face area in a video image, and an oxygen saturation value can be obtained by calculating the two pulse waves with the different wave sections. The calculated result is displayed on the displaying unit through the data line.

Description

A kind of contactless oxygen saturation measurement device based on imaging device
Technical field
Patent of the present invention relates to a kind of real-time blood oxygen measuring device based on imaging device, and this device is mainly used under the surroundings optical illumination condition, non-contacting oxygen saturation measurement.Than the oxygen saturation measurement device of clinical and daily use at present, this device capacity of resisting disturbance is strong, and equipment is common, and is simple to operate, do not contact tested personnel fully, the class that is suitable for burning, is not suitable for the patient of contact blood oxygen instrument.Be more suitable for the health monitoring that general public is used for daily life.
Background technology
(Oxygen saturation SO2) is one of important physical parameter to blood oxygen saturation, and low excessively blood oxygen saturation will cause irreversible hypoxic damage in tissue, therefore in anesthesia, operation process, it is monitored very important.The method that is used for daily Oximetry at present mainly is based on the finger-clipped of photoelectricity volume pulse tracing, nose pastes the contact measuring device of formula, volume subsides formula.
But contact type measurement can cause the discomfort of patient body, and bringing stimulates or pain, even causes that physiological change influences the accuracy of measurement result.And these devices also all are not suitable for contacting human body for a long time, are not suitable for long-time the measurement and daily monitoring at any time.Especially the patient that can not independently cooperate the patient of large-area burns, the patient who suffers from mental sickness, infant etc. also is not suitable for contacting its health with electrode or sensor, and the contact oxygen saturation measurement has had tangible limitation.
Photoelectricity volume pulse tracing (PhotoPlethysmoGraphy, PPG) be to utilize blood to the absorption of light, when in the blood capillary of skin the difference of hemoperfusion amount being arranged, by detection of skin surface light reflection and absorbtivity how much, and then draw pulse wave information, according to the difference of measuring position, also can comprise the microcirculation information of measuring position in the measurement result sometimes.Be to utilize infrared light at first, adding light source throws light on to surveying skin surface, yet the infrared acquisition instrument in daily life and be of little use, and add light source and many times also limited to irradiation and search coverage size, thereby the scope of application and accuracy are surveyed in influence.
Summary of the invention
In order to overcome the drawback that present contact oxygen saturation measurement device exists, the invention provides a kind of visual light imaging equipment that utilizes, the oxygen saturation measurement device under no additional source of light lighting condition, this appliance arrangement is simple, processing ease, capacity of resisting disturbance is strong, and suitable environment is extensive.Be suitable for health monitoring clinical and that general public is daily, have wide development space and application prospect.Its technical scheme is achieved in that a kind of oxygen saturation measurement device based on imaging device, be used for contactless oxygen saturation measurement, it is characterized in that this device by video acquisition unit, signal processing unit, blood oxygen saturation as a result the data wire between display unit and each unit constitute; Described video acquisition unit is reached by two CCD that are added with optical filter that are positioned at people's face the place ahead to be formed by the video capture card that data wire links to each other with CCD; Described signal processing unit is made up of PC main frame or high speed signal treatment circuit; The video acquisition unit of oxygen saturation measurement device is connected with video capture card by described data wire; Video capture card links to each other with PC main frame or high speed signal treatment circuit by described data wire; PC main frame or high speed signal treatment circuit link to each other with the blood oxygen saturation display unit by data wire; The video signal of oxygen saturation measurement device comprises human face's video signal, and this video signal is transferred to video capture card by data wire, and analogue signal is converted into digital signal; Video capture card is by the be connected communication of usb data line with the PC main frame, the video signal that collects is deposited in the memorizer by certain format, the operation upper computer analyzing software, by calculating the change curve of gray average on time domain of human face region in the video image, can draw pulse wave curves, this data message can characterize the blood oxygen saturation information of human body by correlation computations; By data wire result of calculation is shown at described display unit device.
Add the optical filter of different-waveband in the middle of two CCD in the described video acquisition unit device, its target surface and camera lens, optical filter can be 440nm and 520nm, or 470 and 520nm; In these two groups of wave bands, there is a wave band to guarantee that reduced hemoglobin and oxygen and hemoglobin absorptance herein equate in every group of wave band, and differs bigger at another wave band absorptance; Guaranteed the accuracy of blood oxygen saturation test.
Described video acquisition unit device is positioned at 30cm-100cm before the people face, has realized the noncontact of oxygen saturation measurement, and the patient body of avoiding contact type measurement to cause is uncomfortable and paste agent to the damage of skin; The human body that the video acquisition unit device can be gathered video signal can be but be not limited to volume, face, ear-lobe, the palm of the hand, arm etc.
Described video acquisition can but be not limited under the ambient lighting conditions of natural light, daylight lamp or electric filament lamp, take and obtain.
Described oxygen saturation measurement device based on imaging device uses photoelectricity volume pulse tracing, utilize blood that light is absorbed variable quantity and embody pulse wave, by detection of skin surface light reflection and absorbtivity how much, draw the difference of skin blood capillary inner blood groundwater increment, the pulse wave information that is that this groundwater increment embodies.
Described two optical filter wave bands can be but be not limited to 440nm and 520nm, or 470 and the 520nm wave band.
The signal processing unit of described oxygen saturation measurement device based on imaging device can utilize PC as program carrier, realizes the extraction computing of blood oxygen saturation thereon.
The signal processing unit of described oxygen saturation measurement device based on imaging device can utilize the high speed circuit system, and off line realizes, carries out the extraction computing of blood oxygen saturation.
The device of the display unit as a result corresponding data processing system of described oxygen saturation measurement device based on imaging device also has two kinds of ways of realization, carry out sequential operation at PC, the heart rate result of extraction be presented on the display screen or the demonstration carrier by PC control on; At the high speed circuit system, the blood oxygen saturation result of extraction is presented on the demonstration carrier of being controlled by high speed circuit.
Described oxygen saturation measurement device based on imaging device, digital video signal with storage, utilize the reflected light brightness of the pixel grey scale embodiment people face of human face region, it is average that pixel in the selected human face region of each frame is done gray scale, and be that variable is depicted as the gray average time-domain curve with the frame number.
Described oxygen saturation measurement device based on imaging device carries out the Fourier bandpass filtering treatment to the waveform that embodies pulse wave, extracts the pulse wave at 0.7Hz~3Hz wave band.
Described a kind of oxygen saturation measurement device based on imaging device is example with 470nm and 520nm wave band, the clear pulse wave that extracts is got average can obtain I 470 DCAnd I 520 DC
Described a kind of oxygen saturation measurement device based on imaging device detects extreme point and extreme value number to the clear pulse wave that extracts by the differential thresholding algorithm, and detected extreme point is averaged, and can obtain I 470 ACAnd I 520 AC
Described measurement method of blood oxygen saturation based on imaging device, pulse wave average and peak-to-peak value according to obtaining calculate Value obtains oximetry value according to R value curve.
Described analysis software comprises instrument control, data acquisition, data storage, data communication, data importing, data analysis and display module as a result, and display module characterizes human body blood oxygen saturation information by oximetry value as a result.
Beneficial effect
The present invention compared with prior art has following distinguishing feature and good effect:
1. be a kind of contactless measuring method owing to this method, so it can be applicable to baby and burn patient.
2. owing to use visual light imaging equipment, simple to operate and easy realization, and do not have radiation hazradial bundle to tested human body.Simultaneously owing to its simple operability, for the health monitoring in people's daily life provides more facility.
Description of drawings
Fig. 1 is two kinds of way of realization figure of apparatus of the present invention.Wherein
I is video capture device: 1: camera lens 1; 2:470nm wave band optical filter; 3:CCD1; 4: camera lens 2; 5:520nm wave band optical filter; 6:CCD2; 7: image pick-up card 1; 8: image pick-up card 2
II is signal processing unit: IIa: the high speed integrated circuit processing system; The IIb:PC main frame
III is the blood oxygen saturation device displaying result: liquid crystal display
IV is for connecting the data wire of each unit
The basic flow sheet that Fig. 2 upper computer software algorithm is realized.
The specific embodiment
Below in conjunction with accompanying drawing of the present invention, technical scheme of the present invention is carried out clear, complete description.The embodiment of video acquisition unit of the present invention has PC to realize and off line realizes two kinds.
As shown in Figure 1, this device by video acquisition unit (I), signal processing unit (II), blood oxygen saturation as a result the data wire (IV) between display unit (III) and each unit constitute; Video acquisition unit (I) is by CCD (3,6) and the place ahead camera lens (1,4) thereof, optical filter (2,5) and video capture card (7, the 8) composition that links to each other with CCD; Signal processing unit is made up of PC main frame (IIb) or high speed signal treatment circuit (IIa); The video acquisition unit of oxygen saturation measurement device is connected with video capture card by described data wire; Described video capture card links to each other with PC main frame or high speed signal treatment circuit by described data wire; PC main frame or high speed signal treatment circuit link to each other with the blood oxygen saturation display unit by data wire; The video signal of oxygen saturation measurement device comprises human face's video signal, and this video signal is transferred to video capture card by data wire, and analogue signal is converted into digital signal; Described video capture card is by the be connected communication of usb data line with the PC main frame, the video signal that collects is deposited in the memorizer by certain format, the operation upper computer analyzing software, by calculating the change curve of gray average on time domain of human face region in the video image, can draw pulse wave curves, this data message can characterize the blood oxygen saturation information of human body by correlation computations; By data wire result of calculation is shown at described display unit device.
The upper computer analyzing software flow process as shown in Figure 2,
The first step with the video file that collects, is converted to gradation data and storage, chooses human face region in each frame, averages selecting the gray value in the zone.
Second step was variable with the gray average that obtains with the frame number, was depicted as two gray average timing curves.
There was the base band drift phenomenon in the 3rd step at the pulse waveform that obtains, and two gray average curves are carried out the FFT bandpass filtering, can eliminate the influence of base band injustice, obtain the smooth pulse wave of base band clearly, the pulse waveform that obtains is got average, can obtain I 470 DCAnd I 520 DC
The 4th step, the pulse wave of two different-wavebands obtaining is carried out the differential threshold calculations, obtain pulse wave differential signal figure.
In the 5th step, the pulse wave differential signal according to obtaining extracts pulse cycle, by the forward and backward prediction to this point, finds out the peak-to-peak value of pulse wave signal, i.e. I 470 ACAnd I 520 AC
In the 6th step, pulse wave average and peak-to-peak value according to obtaining calculate
Figure BSA00000820143500061
Value according to R value curve, can obtain oximetry value, by data wire the result is presented on the display screen simultaneously.
Though described the present invention with reference to exemplary embodiments, should be appreciated that used term is explanation and exemplary and nonrestrictive term.The spirit or the essence that do not break away from invention because the present invention can specifically implement in a variety of forms, so be to be understood that, above-described embodiment is not limited to any aforesaid details, and should be in the spirit and scope that the claim of enclosing limits explain widely, therefore fall into whole variations in claim or its equivalent scope and remodeling and all should be the claim of enclosing and contain.

Claims (10)

1. oxygen saturation measurement device based on imaging device, be used for contactless oxygen saturation measurement, it is characterized in that this device is by video acquisition unit, signal processing unit, the blood oxygen saturation data wire between display unit and each unit as a result constitutes, described video acquisition unit is reached by two CCD that are added with optical filter that are positioned at people's face the place ahead to be formed by the video capture card that data wire links to each other with CCD, described signal processing unit is made up of PC main frame or high speed signal treatment circuit, the video acquisition unit of oxygen saturation measurement device is connected with video capture card by described data wire, described video capture card links to each other with PC main frame or high speed signal treatment circuit by described data wire, PC main frame or high speed signal treatment circuit link to each other with the blood oxygen saturation display unit by data wire, the video signal of oxygen saturation measurement device comprises human face's video signal, this video signal is transferred to video capture card by data wire, analogue signal is converted into digital signal, described video capture card is by the be connected communication of usb data line with the PC main frame, the video signal that collects is deposited in the memorizer by certain format, the operation upper computer analyzing software, by calculating the change curve of gray average on time domain of human face region in the video image, can draw pulse wave curves, this data message can characterize the blood oxygen saturation information of human body by correlation computations, by data wire result of calculation is shown at described display unit device.
2. a kind of oxygen saturation measurement device based on imaging device according to claim 1, it is characterized in that two CCD in the described video acquisition unit device, add the optical filter of different-waveband in the middle of its target surface and the camera lens, optical filter can be 440nm and 520nm, or 470 and 520nm, in these two groups of wave bands, there is a wave band to guarantee that reduced hemoglobin and oxygen and hemoglobin absorptance herein equate in every group of wave band, and differ bigger at another wave band absorptance, guaranteed the accuracy of blood oxygen saturation test.
3. a kind of oxygen saturation measurement device based on imaging device according to claim 1, it is characterized in that described video acquisition unit device is positioned at 30cm-100cm before the people face, realized the noncontact of oxygen saturation measurement, avoid patient body that contact type measurement causes uncomfortable and paste agent to the damage of skin, the human body that the video acquisition unit device can be gathered video signal can be but be not limited to volume, face, ear-lobe, the palm of the hand, arm etc.
4. the oxygen saturation measurement device based on imaging device according to claim 1, it is characterized in that described video acquisition can but be not limited under the ambient lighting conditions of natural light, daylight lamp or electric filament lamp, take and obtain.
5. a kind of oxygen saturation measurement device based on imaging device according to claim 1 is characterized in that two optical filter wave bands can be but are not limited to 440nm and 520nm, or 470 and the 520nm wave band.
6. the oxygen saturation measurement device based on imaging device according to claim 1, the signal processing unit that it is characterized in that this device can utilize PC as program carrier, realize the extraction computing of blood oxygen saturation thereon, the signal processing unit of this device also can utilize the high speed circuit system, off line realizes, carries out the extraction computing of blood oxygen saturation.
7. the oxygen saturation measurement device based on imaging device according to claim 1, the device of the display unit as a result corresponding data processing system that it is characterized in that this device also has two kinds of ways of realization, carry out sequential operation at PC, the heart rate result who extracts is presented on the display screen or on the demonstration carrier by PC control, at the high speed circuit system, the blood oxygen saturation result of extraction is presented on the demonstration carrier of being controlled by high speed circuit.
8. the oxygen saturation measurement device based on imaging device according to claim 1, it is characterized in that the digital video signal with storage, utilize the reflected light brightness of the pixel grey scale embodiment people face of human face region, it is average that pixel in the selected human face region of each frame is done gray scale, and be that variable is depicted as the gray average time-domain curve with the frame number.
9. the oxygen saturation measurement device based on imaging device according to claim 1, it is characterized in that the waveform that embodies pulse wave is carried out the Fourier bandpass filtering treatment, extract the pulse wave at 0.7Hz~3Hz wave band, the clear pulse wave that extracts is got average can obtain I 470 DCAnd I 520 DC, extreme point and extreme value number by differential thresholding algorithm detection pulse wave are averaged detected extreme point, can obtain I 470 ACAnd I 520 AC, pulse wave average and peak-to-peak value according to obtaining calculate Value obtains oximetry value according to R value curve.
10. the oxygen saturation measurement device based on imaging device according to claim 1 is characterized in that described analysis software comprises instrument control, data acquisition, data storage, data communication, data importing, data analysis and control display module as a result.
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CN104688199A (en) * 2015-03-20 2015-06-10 杭州师范大学 Non-contact type pulse measurement method based on skin pigment concentration difference
CN105353130A (en) * 2015-11-06 2016-02-24 邢丽丽 Automatic tester applied to intelligent electric meter production line
CN105425196A (en) * 2015-11-06 2016-03-23 邢丽丽 Application method for automatic tester for intelligent electric meter production line
CN105740627A (en) * 2016-01-29 2016-07-06 深圳市奋达科技股份有限公司 Heart rate calculating method and device
CN106073801A (en) * 2016-08-16 2016-11-09 深圳信息职业技术学院 A kind of external cavum nasopharyngeum vena systemica blood oxygen saturation formation method and device
CN106264554A (en) * 2015-06-09 2017-01-04 中国科学院软件研究所 A kind of method for detecting blood oxygen saturation based on visible ray and system
CN106510659A (en) * 2016-10-27 2017-03-22 北京雷致科技有限公司 Blood oxygen and heart rate measuring method, measuring device and measuring system
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CN108814619A (en) * 2018-04-19 2018-11-16 广西欣歌拉科技有限公司 The method, system and device of high-precision blood oxygen saturation measurements
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CN109497977A (en) * 2019-01-07 2019-03-22 华东交通大学 Human heart rate and method for detecting blood oxygen saturation and device
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CN104688199A (en) * 2015-03-20 2015-06-10 杭州师范大学 Non-contact type pulse measurement method based on skin pigment concentration difference
CN106264554A (en) * 2015-06-09 2017-01-04 中国科学院软件研究所 A kind of method for detecting blood oxygen saturation based on visible ray and system
CN106264554B (en) * 2015-06-09 2019-12-13 中国科学院软件研究所 visible light-based blood oxygen saturation detection method and system
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CN105353130A (en) * 2015-11-06 2016-02-24 邢丽丽 Automatic tester applied to intelligent electric meter production line
CN105740627A (en) * 2016-01-29 2016-07-06 深圳市奋达科技股份有限公司 Heart rate calculating method and device
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CN106510659A (en) * 2016-10-27 2017-03-22 北京雷致科技有限公司 Blood oxygen and heart rate measuring method, measuring device and measuring system
CN108814619A (en) * 2018-04-19 2018-11-16 广西欣歌拉科技有限公司 The method, system and device of high-precision blood oxygen saturation measurements
CN109008964A (en) * 2018-06-27 2018-12-18 浏阳市安生智能科技有限公司 A kind of method and device that physiological signal extracts
CN109171649A (en) * 2018-08-30 2019-01-11 合肥工业大学 Intelligent imaging formula vital signs detecting instrument
CN109171649B (en) * 2018-08-30 2021-08-17 合肥工业大学 Intelligent image type vital sign detector
CN109512418A (en) * 2018-10-22 2019-03-26 哈尔滨理工大学 A kind of volumetric blood flow pulse imaging reduction motion artifacts method
WO2020114288A1 (en) * 2018-12-04 2020-06-11 紫罗兰家纺科技股份有限公司 Energy product demonstration and detection method
CN109497977A (en) * 2019-01-07 2019-03-22 华东交通大学 Human heart rate and method for detecting blood oxygen saturation and device
CN110132875A (en) * 2019-05-27 2019-08-16 哈尔滨工业大学 The more argument field reconstructing devices of dispersive medium and method based on the fusion of multi-source pulse laser information
CN110132875B (en) * 2019-05-27 2021-09-10 哈尔滨工业大学 Multi-source pulsed laser information fusion-based dispersive medium multi-volume field reconstruction device and method
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CN112890792A (en) * 2020-11-25 2021-06-04 合肥工业大学 Cloud computing cardiovascular health monitoring system and method based on network camera

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