CN103263578B - Traditional Chinese medicine for treating urinary calculus and preparation method thereof - Google Patents
Traditional Chinese medicine for treating urinary calculus and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating urinary calculus and a preparation method of the traditional Chinese medicine, belonging to medical preparations. The traditional Chinese medicine is prepared from the following medicine materials in parts by mass: 12-16 parts of yellow croaker ear-stone, 20-30 parts of lysimachia christinae hance, 10-15 parts of endothelium corneum gigeriae galli, 12-16 parts of herba pyrrosiae, 15-18 parts of liquidambar formoana hance seeds, 12-15 parts of cowherb seeds, 8-12 parts of radix ophiopogonis, 10-15 parts of rhizoma alismatis, 15-18 parts of white mustard seeds, 15-18 parts of raphanus sativus seeds and 8-12 parts of talc, wherein the white mustard seeds and the seeds of raphanus sativus need to be fried in advance. The preparation method comprises the following steps of: firstly, frying the white mustard seeds and the seeds of raphanus sativus, furthermore washing, drying, crushing and disinfecting the medicine materials, mixing according to the ratio of the formula, adding water to soak, introducing steam, heating for three times and extracting the effective ingredients in the medicine materials, filtering the medicine materials into extract, furthermore drying, crushing and grinding into powder, and finally pressing the extract into tablets or putting into capsules, wherein each capsule or each tablet contains 1g of the medicine. The medicine disclosed by the invention is good in therapeutic effect, free of side effect and applicable to treatment on urinary calculus patients.
Description
Technical field
The present invention relates to medicinal preparation, the medicine in particular to by prepared from traditional Chinese medicines, furthermore, relates to the medicine for the treatment of urinary system calculus.
Background technology
Urinary system calculus is a kind of commonly encountered diseases.Urinary system calculus is found in any position of kidney, bladder, ureter and urethra, but take kidney and ureteral calculus as common.Clinical manifestation has different because position, calculus place is different.The typical case of kidney and ureteral calculus shows as renal colic and hematuria, and before calculus causes angor outbreak, patient is without any sensation; Due to certain inducement, as strenuous exercise, work, long-distance ride etc., there is suddenly the violent angor of a side waist, and to lower abdomen and perineal position radiation, with abdominal distention, feel sick, vomiting, hematuria that degree is different; Vesical calculus main manifestations is dysuria and the pain of urinating.Doctor trained in Western medicine adopts agents alleviate pain conventionally, serious employing surgical calculus removing.
China's medical science has very rich experience to the treatment of urinary system calculus.In recent years, relate in a large number treat urinary system calculus pharmaceutical formulation application Chinese patent.For example, No. 200510071080.0 < < Chinese medicine preparation (stone dissolving capsule) > > who treats urinary system calculus, No. 200810107887.9 < < Chinese medicine > > who treats urinary calculus and tumor, 200910212923.2 the Chinese medicine composition > > of number < < treatment urinary system calculus, No. 201010544151.5 < < Chinese medicine composition > > who treats urinary system calculus, No. 201110309267.5 < < Chinese medicine > > who treats urinary system calculus, mono-kind of No. 201210346422.5 < < treats the Chinese medicine preparation > > of urinary system calculus and a No. 201310014009.3 < < Chinese medicine for the treatment of urinary system calculus and preparation method thereof > > etc.These medicines no doubt have certain curative effect, but how on earth curative effect there is no from understanding, and old friends, at the more effective medicine of research, are still people's health service.
Summary of the invention
Object of the present invention is just to provide a kind of Chinese medicine for the treatment of urinary system calculus, increases the types of drugs for the treatment of urinary system calculus, eliminates patient suffering.
Another object of the present invention is to provide the method for making of above-mentioned Chinese medicine, enables practical application.
The Chinese medicine for the treatment of urinary system calculus of the present invention is to be made by the medical material of following quality proportioning:
Asteriscus Pseudosciaenae 12～16, Herba Lysimachiae 20～30, Endothelium Corneum Gigeriae Galli 10～15, Folium Pyrrosiae 12～16, Fructus Liquidambaris 15～18, Semen Vaccariae 12～15, Radix Ophiopogonis 8～12, Rhizoma Alismatis 10～15, Semen Sinapis Albae 15～18, Semen Raphani 15～18, Talcum 8-12; The parch in advance of described Semen Sinapis Albae and Semen Raphani.
The preferred mass proportioning of this Chinese medicine is:
Asteriscus Pseudosciaenae 14, Herba Lysimachiae 25, Endothelium Corneum Gigeriae Galli 12, Folium Pyrrosiae 14, Fructus Liquidambaris 16, Semen Vaccariae 14, Radix Ophiopogonis 10, Rhizoma Alismatis 13, Semen Sinapis Albae 16, Semen Raphani 16, Talcum 10; The parch in advance of described Semen Sinapis Albae and Semen Raphani.
In above-mentioned formula, Asteriscus Pseudosciaenae is the otolith in Sciaenidae animal Carnis Pseudosciaenae (Pseudosciaena crocea) skull, salty in the mouth, property is put down, and has fossil, treating stranguria, antiinflammation (seeing 1438 pages of Jiangsu new medical college volume < < Chinese medicine voluminous dictionary > >); Herba Lysimachiae is the whole herb with root of labiate HUOXUEDAN (Glechoma longituba), bitter but sweet flavor, cool in nature, has heat clearing away, diuresis, antitussive, detumescence, detoxicating functions (seeing Jiangsu new medical college volume < < Chinese medicine voluminous dictionary > > 1399-1400 page); Endothelium Corneum Gigeriae Galli is the dry gizzard tunica intima of Phasianidae animal man chicken (Gallus gallus domesticus), sweet in the mouth, property flat, can removing food stagnancy stagnant, strengthening the spleen and stomach (seeing 1203 pages of < < Chinese medicine voluminous dictionary > >); Folium Pyrrosiae is the leaf of Plants of Polypodiaceae Folium Pyrrosiae (Pyrrosia lingua), bitter but sweet flavor, cool in nature, there is relieving stranguria by diuresis, the lung heat clearing effect (seeing 579 pages of < < Chinese medicine voluminous dictionary > >) that expels the heat-evil; Fructus Liquidambaris is the fruit of Hamamelidaceae Plants sweetgum (Liquidambar formoana), bitter in the mouth, property is put down, can dispel the wind, dredging collateral, diuretic, dehumidifying (seeing 2485 pages of < < Chinese medicine voluminous dictionary > >); Semen Vaccariae is the seed of pinkwort Vaccaria segetalis (Vaccaria segetalis), bitter in the mouth, property is put down, and has promoting the circulation of blood to stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, detumescence sore effect (seeing 311 pages of < < Chinese medicine voluminous dictionary > >); Radix Ophiopogonis, it is Radix Ophiopogonis, tuber for liliaceous plant dwarf lilyturf (Ophiopogon japonicus), sweet and slightly bitter taste, property flat, can nourishing YIN and moistening the lung, the liver benefiting that clears away heart-fire (seeing 1024 pages of < < Chinese medicine voluminous dictionary > >); Rhizoma Alismatis is the tuber of Notes On Alism At Aceae Rhizoma Alismatis (Alisma plantago-aquatica), sweet in the mouth, cold in nature, can diuretic, eliminating dampness by diuresis, (seeing 1461 pages of < < Chinese medicine voluminous dictionary > >) expels the heat-evil; Semen Sinapis Albae is the seed of crucifer Caulis et Folium Sinapis albee (Brassica alba), acrid in the mouth, warm in nature, energy promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain (seeing 716 pages of < < Chinese medicine voluminous dictionary > >); Semen Raphani is the mature seed of crucifer Lay clothes (Raphanus sativus), acrid in the mouth, hot in nature, can the therapeutic method to keep the adverse QI flowing downwards Dingchuan, (seeing 1801 pages of < < Chinese medicine voluminous dictionary > >) eliminates indigestion and phlegm; Talcum is the blocks of silicates mineral talc (Talc), slightly sweet flavor, cold in nature, energy heat clearing away, eliminating dampness by diuresis, sharp key (seeing 2415 pages of < < Chinese medicine voluminous dictionary > >).
Above-mentioned medical material should meet the regulation under each medical material item in one of < < Chinese Pharmacopoeia > > nineteen ninety-five version.
The Chinese medicine method for making for the treatment of urinary system calculus is prior parch Semen Sinapis Albae and Semen Raphani, then 11 taste medical materials in formula are cleaned respectively, with hot-air seasoning, is processed into fragment, then uses disinfection by ultraviolet light; After pressing again formula proportion and mixing, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated to boiling 3 times, 1～2 hour for the first time, 0.5～1 hour for the second time, 0.5 hour for the third time, so far wherein active ingredient proposed substantially; After filtering, medicinal liquid is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; Finally pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every 1g, obtain tablet or capsule.
The above-mentioned pharmaceutical technology that is pressed into tablet comprises: 1. the 60 order powder that make are added to adjuvant, main adjuvant is adhesive modified starch, mix homogeneously; 2. in mixed powder, add water as wetting agent, make soft material; 3. soft material extruding is sieved, granulation; 4. granule is through super-dry, make its moisture be applicable to and evenly, grain graininess is suitable; 5. dried particles, through check, confirms to meet the requirement of tablet; 6. with Chong Yashi or rotary tablet machine, extrude tablet, what be up to the standards is finished product.
The pharmaceutical technology of above-mentioned capsule comprises: 1. prepare or buy and take the capsulae vacuus that gelatin is primary raw material; 2. the 60 order powder that make are crossed to sieve No. 6, the fine powder obtaining is standby; 3. with the artificial medicated powder of loading, enter soft capsule, or pack medicated powder into automatic filling machine; 4. the effective ingredient of medicated powder and quality are tested, the qualified rear glue with gelatin, in the sealing of capsule capping place, obtains finished product.
Inventor points out: this Chinese medicine also can be prepared into any conventional peroral dosage form by conventional method of Chinese medicinal.No matter which kind of dosage form, all must deposit according to the relevant regulations of drug stock control.
The Chinese medicine using method of urinary system calculus of the present invention is oral, warm water delivery service, every day 2 times, each 4～5/sheet.
The Chinese medicine for the treatment of urinary system calculus of the present invention is the formula drawing in long term medical practice.Chinese medicine of the present invention is evident in efficacy in clinical use, and effective percentage reaches more than 80%.Model case is as follows:
Case one: Hu, female, 31 years old.In mid-October, 2007 lumbago burst, hurt like hell, has obvious hematuria, takes and has an injection all to no effect.By Guiyang Medical College, be diagnosed as left renal calculus, upon somebody's introduction, take Chinese medicine of the present invention 5 days, be obstructed suddenly urinating noon one day, and twinge has thing to block like urethra, firmly helps to urinate, the calculus ejection as Semen Glycines is large, and lumbago is gradually good.By Chemical Examination Material in Hospital film making report, two kidneys and ureter have no calculus shade, after half a year, follow up a case by regular visits to, and lumbago is not sent out.
Case two: health, man, 47 years old.Patient does manual work because going out in way, finds lumbago unbearably, and EVAC HOSP inspection is ureteral calculus, due to economic cause hospitalization not, changes and takes this Chinese medicine 20 days, successively from urine, discharges 5 pieces, calculus not of uniform size, and the ill symptomses such as lumbago disappear substantially.
Case three: permitted certain, man.Because finding the symptoms such as flank pain, remove examination in hospital, be diagnosed as two renal calculus, through taking medicine of the present invention after 20 days, from urine, discharge 7, calculus not of uniform size, large as Semen Glycines, little of Semen setariae, the symptoms such as pain all disappear, and follow up a case by regular visits to half a year, recurrence.
Inventor points out: can calculus discharge smoothly, also depends on position, size and the fineness of calculus.
The Chinese medicine for the treatment of urinary system calculus of the present invention, medical material is easy to get, easy to process, and curative effect is obvious, has no side effect.Be applicable to treat urinary system calculus disease.
The specific embodiment
Embodiment 1
By the Chinese medicine method for making for the treatment of urinary system calculus, be prior parch Semen Sinapis Albae and Semen Raphani, then above-mentioned 11 taste medical materials cleaned respectively, with hot-air seasoning, be processed into fragment, then use disinfection by ultraviolet light; Get again Asteriscus Pseudosciaenae 14g, Herba Lysimachiae 25g, Endothelium Corneum Gigeriae Galli 12g, Folium Pyrrosiae 14g, Fructus Liquidambaris 16g, Semen Vaccariae 14g, Radix Ophiopogonis 10g, Rhizoma Alismatis 13g, Semen Sinapis Albae 16g, Semen Raphani 16g, Talcum 10g, puts into the pond that pottery or copper tank or wooden barrel or cement is built into and adds water retting, and pass into steam heated to boiling 3 times, and 2 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, wherein active ingredient is proposed substantially; The medicinal liquid filtering is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; Finally pharmaceutical technology routinely, is pressed into tablet, and every 1g, obtains tablet product.
Embodiment 2
Preparation process is with embodiment 1.Grind to form 60 object drug powders, finally pharmaceutical technology routinely, incapsulates, and every 1g, obtains capsule product.
Claims (3)
1. treat a Chinese medicine for urinary system calculus, it is characterized in that this Chinese medicine is to be made by the medical material of following quality proportioning:
Asteriscus Pseudosciaenae 12～16, Herba Lysimachiae 20～30, Endothelium Corneum Gigeriae Galli 10～15, Folium Pyrrosiae 12～16, Fructus Liquidambaris 15～18, Semen Vaccariae 12～15, Radix Ophiopogonis 8～12, Rhizoma Alismatis 10～15, Semen Sinapis Albae 15～18, Semen Raphani 15～18, Talcum 8-12; The parch in advance of described Semen Sinapis Albae and Semen Raphani.
2. according to Chinese medicine claimed in claim 1, it is characterized in that this Chinese medicine is to be made by the medical material of following quality proportioning:
Asteriscus Pseudosciaenae 14, Herba Lysimachiae 25, Endothelium Corneum Gigeriae Galli 12, Folium Pyrrosiae 14, Fructus Liquidambaris 16, Semen Vaccariae 14, Radix Ophiopogonis 10, Rhizoma Alismatis 13, Semen Sinapis Albae 16, Semen Raphani 16, Talcum 10; The parch in advance of described Semen Sinapis Albae and Semen Raphani.
3. the method for preparing Chinese medicine described in claim 1 or 2, is characterized in that prior parch Semen Sinapis Albae and Semen Raphani, then 11 taste medical materials in formula are cleaned respectively, with hot-air seasoning, is processed into fragment, then uses disinfection by ultraviolet light; After pressing again formula proportion and mixing, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated to boiling 3 times, 1～2 hour for the first time, 0.5～1 hour for the second time, 0.5 hour for the third time, so far wherein active ingredient proposed substantially; After filtering, medicinal liquid is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; Finally pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every 1g, obtain tablet or capsule.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260202A (en) * | 1999-08-30 | 2000-07-19 | 张振礼 | Medicament for treating urinary calculus and its preparation method |
| CN1723919A (en) * | 2005-07-20 | 2006-01-25 | 王友富 | Medicine for treating urinary system stone disease, and its prepn. method |
| CN101721642A (en) * | 2008-11-03 | 2010-06-09 | 颜奎峰 | Medicine for treating calculus of urinary system and preparation method thereof |
| CN101732602A (en) * | 2009-12-31 | 2010-06-16 | 谢运洪 | Medicament for treating calculi and preparation method thereof |
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- 2013-06-17 CN CN201310237360.9A patent/CN103263578B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260202A (en) * | 1999-08-30 | 2000-07-19 | 张振礼 | Medicament for treating urinary calculus and its preparation method |
| CN1723919A (en) * | 2005-07-20 | 2006-01-25 | 王友富 | Medicine for treating urinary system stone disease, and its prepn. method |
| CN101721642A (en) * | 2008-11-03 | 2010-06-09 | 颜奎峰 | Medicine for treating calculus of urinary system and preparation method thereof |
| CN101732602A (en) * | 2009-12-31 | 2010-06-16 | 谢运洪 | Medicament for treating calculi and preparation method thereof |
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