CN103251821A - Medicine for treating wind-heat headache and migraine headache and preparation method of medicine - Google Patents
Medicine for treating wind-heat headache and migraine headache and preparation method of medicine Download PDFInfo
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Abstract
The invention discloses a medicine for treating wind-heat headache and migraine headache and a preparation method of the medicine. The medicine is mainly prepared from the following materials in certain parts by weight: ginseng, radix peucedani, notopterygium root, radix angelicae tuhuo, gastrodia elata and liquorice. The medicine disclosed by the invention has the effects of dispersing wind, clearing heat and calming nerves and is rapid in response, short in course of treatment and high in recovery rate in treating wind-heat headache and migraine headache.
Description
Technical field
The present invention relates to a kind of headache due to pathogenic wind-heat and migrainous medicine and preparation method thereof for the treatment of, belong to the field of Chinese medicines.
Technical background
Headache due to pathogenic wind-heat and migraine are a kind of headaches that is caused by affection due to external wind and heat.Disease is seen the head distending pain, fever with aversion to wind, and the turbid tears of nasal obstruction stream, or conjunctival congestion is flushing, thirst and liking drink, constipation dark coloured urine, yellow and thin fur, floating and rapid pulse etc.Headache due to pathogenic wind-heat has gently to be had heavily, and various pain forms all can occur, and pain also the nausea and vomiting phenomenon can occur sometimes.Headache due to pathogenic wind-heat brings serious harm for people's physical and mental health, has had a strong impact on people's daily life and work.At present, because Western medicine can't effectively be treated headache due to pathogenic wind-heat and migraine, and has certain side effect, therefore, there is very big demand in people to effective treatment headache due to pathogenic wind-heat and migrainous Chinese medicine.
Summary of the invention
The inventor has found effective treatment headache due to pathogenic wind-heat and migrainous medicine finally, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just provides a kind of headache due to pathogenic wind-heat and migrainous composition of medicine for the treatment of.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention selects Radix Ginseng, Poria, Fructus Aurantii, Radix Platycodonis, Radix Bupleuri, Radix Peucedani, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Herba Menthae, Radix Ligustici Brachylobi, Rhizoma Gastrodiae, Herba Asari and Radix Glycyrrhizae to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can treat headache due to pathogenic wind-heat and migrainous recurrence fast.Wherein select for use Radix Ginseng to be because its nature and flavor are sweet little sweet, temperature is gone into spleen, lung meridian, and strongly invigorating primordial QI is arranged, promote the production of body fluid admittedly take off, the function of calming the nerves, it is deficient to control impairment caused by overstrain, lack of appetite, asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Select for use Poria to be because its property slightly sweet flavor is flat, go into the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Selecting Fructus Aurantii for use is that lung, spleen, large intestine channel are gone in cold, and dispelling the stagnated QI is arranged because of its nature and flavor toil, row expectorant, and the function of removing food stagnancy is controlled chest and diaphragm expectorant and is stagnated, the feeling of stuffiness in chest, the side of body expands, food stagnation, eructation, vomiting weighs proctoptosis, uterine prolapse behind the dysentery.Select for use Radix Platycodonis to be because its nature and flavor toil is flat, go into lung, stomach warp, lung qi dispersing gas is arranged out, the function of the evacuation of pus of eliminating the phlegm is controlled the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Selecting Radix Bupleuri for use is that liver, gallbladder meridian are gone in cold, and reconciling superficies and interior is arranged, and be soothing the liver because of its nature and flavor hardship, and the function of yang invigorating is controlled alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Selecting Radix Peucedani for use is because of its nature and flavor suffering, hardship, is slightly cold, and returns lung meridian, and diffusing wind heat clearing away is arranged, and the function of lowering the adverse-rising QI to resolve phlegm is controlled the cough due to pathogenic wind-heat, abundant expectoration, and the expectorant dyspnea of heat type is full, and it is yellow thick to cough up phlegm.Select for use Rhizoma Et Radix Notopterygii to be because its nature and flavor are arduous, temperature is gone into bladder, kidney channel, and diffusing exterior cold is arranged, wind-damp dispelling, and the function in sharp joint, the wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select for use Radix Angelicae Pubescentis to be because its nature and flavor are arduous, temperature is gone into kidney, urinary bladder channel, dispels the wind, and win and wet, cold expelling, the function of pain relieving is controlled anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Selecting Rhizoma Chuanxiong for use is because its nature and flavor suffering, and temperature is gone into liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, and the function of promoting blood circulation and stopping pain is controlled air-cooled headache and is revolved dizzyly, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Selecting Herba Menthae for use is because its nature and flavor suffering, and lung, Liver Channel are gone in cold, and dispelling wind is arranged, and heat radiation is warded off dirtyly, and the function of detoxifcation is controlled affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select for use Radix Ligustici Brachylobi to be because the sweet suffering of its nature and flavor is dispeled the wind, the analgesic function is controlled diseases caused by exogenous pathogenic factor table disease, and it is giddy to have a headache.Select for use Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, go into Liver Channel, endogenous wind stopping is arranged, the function of arresting convulsion is controlled dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia, aphasia, Xiao Jing Epilepsy wind symptom.Selecting Herba Asari for use is that temperature is gone into lung, kidney channel because of its nature and flavor suffering, dispel the wind, and cold expelling, row water is opened the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
The specific embodiment
The consumption of component drug of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in the following weight scope
Radix Ginseng 10-20 gram Poria 10-20 gram Fructus Aurantii 10-20 gram
Radix Platycodonis 10-20 gram Radix Bupleuri 10-20 gram Radix Peucedani 15-25 gram
Rhizoma Et Radix Notopterygii 15-25 gram Radix Angelicae Pubescentis 10-20 gram Rhizoma Chuanxiong 10-20 gram
Herba Menthae 10-15 gram Radix Ligustici Brachylobi 10-15 gram Rhizoma Gastrodiae 10-15 gram
Herba Asari 3-6 gram Radix Glycyrrhizae 8-15 gram
Wherein, be preferably
Radix Ginseng 15 gram Poria 15 gram Fructus Aurantiis 15 grams
Radix Platycodonis 15 gram Radix Bupleuri 15 gram Radix Peucedanis 20 grams
Rhizoma Et Radix Notopterygii 20 gram Radix Angelicae Pubescentiss 15 gram Rhizoma Chuanxiongs 15 grams
Herba Menthae 12 gram Radix Ligustici Brachylobis 12 gram Rhizoma Gastrodiaes 12 grams
Herba Asari 5 gram Radix Glycyrrhizaes 12 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Radix Ginseng: except removing LU, cutting;
2, Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
3, Fructus Aurantii: remove flesh, nuclear, edulcoration soaks slightly, pulls out, moistens softly, can pinch doubling degree of being with hands, and section is dried;
4, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through the back section, dry;
5, Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
6, Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;
7, Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section is dried;
8, Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;
9, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
10, Herba Menthae: choose clean impurity, remove undesirable root, leaf is trembled down in addition put earlier, then stem is sprayed clear water, run through the back cutting, dry, again with leaf and even;
11, Radix Ligustici Brachylobi: remove residual stem, be soaked in water, pull out, run through the back section, dry;
12, Rhizoma Gastrodiae: choose decontamination, be soaked in water to seventy percent saturating, pull out, dry in the air slightly, moisten to internal and external temperature evenly again, section is dried;
13, Herba Asari: Ex-all impurity, water spray profit, cutting is in time dried;
14, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing.
Two, preparation
1, Radix Ginseng, Poria, Fructus Aurantii, Radix Platycodonis, Radix Bupleuri, Radix Peucedani, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Herba Menthae, Radix Ligustici Brachylobi, Rhizoma Gastrodiae, Herba Asari, the Radix Glycyrrhizae with described weight decocts with water, add for the first time 4 times of amounts of water, soaked 30 minutes, intense fire decocts boiling 10 minutes, used slow fire boiling again 20 minutes, time decoction liquor of namely winning.
2, will filter the back medicinal residues for the first time and add 2 times of amounts of water, decoct boiling, namely get decoction liquor for the second time in 20 minutes with slow fire boiling again.
3, twice decoction liquor mixed, will boil liquid and be divided into 2 doses and get final product.
Medicine of the present invention has wind and heat dispersing, the effect of mind tranquilizing and the heart calming, and treatment headache due to pathogenic wind-heat and migraine instant effect, short treating period does not recur, the cure rate height.
Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests comprise that the animal toxicity test of medicine of the present invention and clinical observation test.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day twice, observes administration reaction every day, and the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 150 examples for medical treatment, headache due to pathogenic wind-heat 80 examples wherein, migraine 70 examples.
2, diagnostic criteria
Migraine: mode of onset can be and breaks out, or slow onset, outbreak repeatedly, and in time, end during pain.The persistent period of pain is changeable.
Headache due to pathogenic wind-heat: mode of onset can be and breaks out, with performances such as headache, stiffness of the nape, nausea and vomiting, nystagmus, Hiccough and deaf, sweating, pale complexions.Denumerable minute, a few hours or a couple of days, several weeks, very then long-term pain endlessly.
3, Therapeutic Method
Select above-mentioned medicament for use, take to the patient, the migraineur takes 1 dose at every turn, every day early, respectively obey 1 time evening, 7 days is a course for the treatment of, takes four courses for the treatment of continuously.Headache due to pathogenic wind-heat patient takes 1 dose at every turn, and every day is early, middle and late respectively obeys 1 time, and 7 days is a course for the treatment of, takes seven courses for the treatment of continuously.
4, efficacy assessment standard
Produce effects: treatment back clinical symptom disappearance, it is normal that body constitution is recovered, and observes and do not have the recidivist half a year;
Take a turn for the better: clinical symptoms is obviously improved, the head pain relief, and body constitution is progressively recovered;
Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, with Drug therapy headache due to pathogenic wind-heat of the present invention and migraineur's 150 examples, headache due to pathogenic wind-heat patient 80 examples wherein, produce effects 76 examples as a result, obvious effective rate is 95%, 1 example that takes a turn for the better, improvement rate is 1.25%, invalid 3 examples, total effective rate is 96.25%.Migraineur's 70 examples, produce effects 67 examples as a result, obvious effective rate is 95.71%, 2 examples that take a turn for the better, improvement rate is 2.86%, invalid 1 example, total effective rate is 98.57%.
Claims (3)
1. treat headache due to pathogenic wind-heat and migrainous medicine for one kind, it is characterized in that: it is to be made by the crude drug in the following weight range:
Radix Ginseng 10-20 gram Poria 10-20 gram Fructus Aurantii 10-20 gram
Radix Platycodonis 10-20 gram Radix Bupleuri 10-20 gram Radix Peucedani 15-25 gram
Rhizoma Et Radix Notopterygii 15-25 gram Radix Angelicae Pubescentis 10-20 gram Rhizoma Chuanxiong 10-20 gram
Herba Menthae 10-15 gram Radix Ligustici Brachylobi 10-15 gram Rhizoma Gastrodiae 10-15 gram
Herba Asari 3-6 gram Radix Glycyrrhizae 8-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Ginseng 15 gram Poria 15 gram Fructus Aurantiis 15 grams
Radix Platycodonis 15 gram Radix Bupleuri 15 gram Radix Peucedanis 20 grams
Rhizoma Et Radix Notopterygii 20 gram Radix Angelicae Pubescentiss 15 gram Rhizoma Chuanxiongs 15 grams
Herba Menthae 12 gram Radix Ligustici Brachylobis 12 gram Rhizoma Gastrodiaes 12 grams
Herba Asari 5 gram Radix Glycyrrhizaes 12 grams.
3. according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:
(1) gets the raw materials ready
(1) Radix Ginseng: except removing LU, cutting;
(2) Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
(3) Fructus Aurantii: remove flesh, nuclear, edulcoration soaks slightly, pulls out, moistens softly, can pinch doubling degree of being with hands, and section is dried;
(4) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through the back section, dry;
(5) Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
(6) Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;
(7) Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section is dried;
(8) Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;
(9) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
(10) Herba Menthae: choose clean impurity, remove undesirable root, leaf is trembled down in addition put earlier, then stem is sprayed clear water, run through the back cutting, dry, again with leaf and even;
(11) Radix Ligustici Brachylobi: remove residual stem, be soaked in water, pull out, run through the back section, dry;
(12) Rhizoma Gastrodiae: choose decontamination, be soaked in water to seventy percent saturating, pull out, dry in the air slightly, moisten to internal and external temperature evenly again, section is dried;
(13) Herba Asari: Ex-all impurity, water spray profit, cutting is in time dried;
(14) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing;
(2) preparation
(1) Radix Ginseng, Poria, Fructus Aurantii, Radix Platycodonis, Radix Bupleuri, Radix Peucedani, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Herba Menthae, Radix Ligustici Brachylobi, Rhizoma Gastrodiae, Herba Asari, the Radix Glycyrrhizae with described weight decocts with water, add for the first time 4 times of amounts of water, soaked 30 minutes, intense fire decocts boiling 10 minutes, used slow fire boiling again 20 minutes, time decoction liquor of namely winning;
(2) will filter the back medicinal residues for the first time and add 2 times of amounts of water, decoct boiling, namely get decoction liquor for the second time in 20 minutes with slow fire boiling again;
(3) twice decoction liquor mixed, will boil liquid and be divided into 2 doses.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104857313A (en) * | 2015-06-24 | 2015-08-26 | 吉首大学 | Traditional Chinese medicine composition preparation for treating migraine and preparation method thereof |
CN105106908A (en) * | 2015-09-23 | 2015-12-02 | 谢桂凤 | Medicine for treating infantile influenza |
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CN1232695A (en) * | 1999-03-09 | 1999-10-27 | 李胤良 | Health beverage capable of preventing and curing cold in the four seasons |
CN1335163A (en) * | 2001-08-13 | 2002-02-13 | 邹义达 | Chinese medicine for treating cold and cough |
CN1846746A (en) * | 2005-04-04 | 2006-10-18 | 吴修平 | Chinese medicine ginseng-notopterygium powder for treating rhinitis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104857313A (en) * | 2015-06-24 | 2015-08-26 | 吉首大学 | Traditional Chinese medicine composition preparation for treating migraine and preparation method thereof |
CN105106908A (en) * | 2015-09-23 | 2015-12-02 | 谢桂凤 | Medicine for treating infantile influenza |
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Application publication date: 20130821 |