CN103229730B - Method for carrying out circadian rhythm research under microwave exposure with video monitoring function - Google Patents
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Abstract
The invention provides a method for carrying out circadian rhythm research under microwave exposure with a video monitoring function, which comprises a system mainly provided with a light control function, a temperature, humidity and light intensity acquisition function, a video monitoring function, an alarm function and microwave generation and measurement function modules, wherein the working process of the whole system is as follows: if the program is normally started, the system waits for manual configuration of a manual interaction interface; after receiving a command for starting work, firstly setting the value of the working state flag to be 0, and then executing tasks set by the functional modules in the system in parallel. The method for researching the circadian rhythm under microwave exposure with the video monitoring function simulates the environment monitoring of day and night light generation, temperature, humidity, light intensity, microwave irradiation and the like by an automatic method, has the functions of video monitoring and experimental recording, and effectively improves the research meticulous and working efficiency in the aspect.
Description
Technical field
The invention belongs to Study system field, be specifically related to a kind of method of carrying out circadian rhythm research under Microwave exposure with video monitoring function.
Background technology
Along with the development of wireless communication technology, microwave communication technology is widely used in people's production and life, bring facility to people's production and life on the one hand, also around people, formed on the other hand a complicated electromagnetic environment, and whether these complicated electromagnetic environments impact people are healthy, cause people's concern.The increasing scientist impact of electromagnetic wave on organism that begin one's study, and obtained many significant achievements in this research field, experimental results show that the microwave signal long-term irradiation human body of some strength will affect the function of human body.This impact on function of human body has the form of expression of contradiction, may affect health of people on the one hand, and on the other hand can be for micro-wave therapeutic disease.How the scientific and rational microwave technology of utilizing is an important topic of studying at present.
Rationally utilizing in the research of microwave, under Microwave exposure, circadian research is an important research content.So-called biological circadian rhythm refers to that the various physiological functions of organism adapt to changing round the clock of external environment and rule cycle of setting up.Nature, living nature have the distinctive rigorous rhythm and pace of moving things of itself.After external environment changes, will exert an influence to biological circadian rhythm, serious will affect biological physiological function health.Because human body has self-repairing capability, under Microwave exposure, research is not different on function of human body impact in the same time, concrete manifestation comprises circadian impact, may affect large (sensitization time) in certain hour section, and in certain hour impact lower (insensitive time), carry out if be chosen in insensitive time point in micro-wave therapeutic process, contribute to reduce the side effect of micro-wave therapeutic, be conducive to medical and health care system development.In the experiment of circadian rhythm research, can adopt illumination in 12 hours and 12 hours dark 12LD light system or other LD light systems, the relation round the clock that simulation is actual.
Carrying out at present circadian rhythm research under Microwave exposure does not also have special equipment, in process of experimental, will solve following problem.
1. the problem that circadian rhythm research light system produces automatically
No matter adopt 12LD light system or other light system, in experiment, main method is in darkroom, to carry out the switch lamp control of timing, be mainly Artificial Control method at present, cause larger manpower waste, and Artificial Control 12LD light also cannot ensure on time precision.
2. microwave timing exposure problem
In biological circadian rhythm research process under Microwave exposure, generally can select the different time periods to carry out microwave irradiation, and then study physiological function sensitization time point and insensitive time point on circadian rhythm impact under Microwave exposure of tested biology.In current experimentation, not only the equipment such as microwave source instrument, power amplification instrument, transmitting antenna to be integrated, and need manually to carry out microwave signal transmitting and stop the control of launching in the time period of specifying by requirement of experiment, not only affect the time precision of microwave irradiation, and manpower is had relatively high expectations, manpower waste is more serious.
3. environmental monitoring problem
Affecting biological circadian environmental factor has a variety ofly, comprises Microwave exposure, temperature, humidity, intensity of illumination etc.Under Microwave exposure, in biological circadian rhythm process of experimental, generally need the environmental factors such as fixed temperature, humidity and intensity of illumination, just can determine that experimental result is subject to this single-factor influence of Microwave exposure.Therefore, in a period of time that starts to carry out in experiment, by animal used as test being carried out to 12LD or other appointment adaptation light system of light system and the raising of environment, set up stable circadian rhythm.Then carrying out long-term Microwave exposure, research Microwave exposure is on the circadian impact of biology.In actual process of experimental, the environmental factors such as temperature, humidity and light intensity are surveyed several time points for general one day, can not record complete environmental factor index, can not get rid of to a certain extent the impact of other environmental factor completely at present.
4. biological activity rule monitoring problem
In order to reduce the impact of the tested animal of constraint (being generally to test with rat or mouse) on experimental study, generally adopt mouse cage as animal used as test scope.Due to the long-term experiment under LD, mechanics and scope of activities that manually cannot recording laboratory animal, this content can show tested animal stress reflect under Microwave exposure to a certain extent, proposes a solution at present there are no people.
Summary of the invention
In order to solve above-mentioned not enough problem of the prior art, the invention provides a kind of method of carrying out circadian rhythm research under Microwave exposure with video monitoring function, simulate the environmental monitorings such as light generation processed round the clock, temperature, humidity, light intensity, microwave irradiation with automated method, and there is video monitoring and experimental record function, effectively improve careful property and the operating efficiency of research in this respect.
For achieving the above object, the technical solution adopted in the present invention is:
The method of carrying out circadian rhythm research under Microwave exposure with video monitoring function of the present invention, comprise that is mainly disposed an illumination control function, temperature, humidity and intensity collection function, video monitoring function, the system of warning function and microwave generation and these functional modules of measurement function, the course of work of whole system is as follows: be normal start-up routine, and the human configuration at system wait man-machine interactively interface; When receiving after the order of starting working, the value that first operating state mark is set is 0, the task that then functional module described in executed in parallel system is set.
Preferably, described human configuration mainly comprises the settings of light configuration processed, temperature, humidity, intensity collection cycle and alarm door limit value, microwave irradiation configuration; Various LD light systems are supported in described light system configuration, mainly comprise the initial time of turning on light, the setting of turn on light duration and light intensity; Described intensity collection cycle and the setting of alarm door limit value comprise the settings such as intensity collection cycle, daytime light intensity threshold value, night threshold value; Described temperature, humidity collection cycle and the setting of alarm door limit value comprise collection period, threshold value setting; The setting of described microwave irradiation parameter is included in irradiates initial time, irradiates the parameter settings such as duration, irradiating microwaves frequency, intensity, delayed startup number of days under the LD light system of setting.
Preferably, described illumination control function is mainly carried out illumination control according to light configuration information processed, simulates illumination rule round the clock.
Preferably, described temperature, humidity collection function are mainly carried out periodicity temperature, humidity collection and record, the variation of monitoring experiment ambient temperature, humidity; If temperature exceeds threshold value, will report to the police by alarm module, ensure that experiment is not acted upon by temperature changes.
Preferably, described intensity collection function is mainly carried out periodic intensity collection and record, the variation of monitoring experiment environmental light intensity; According to light configuration information processed, monitor whether the light intensity of experimental situation exceeds the threshold value of this time, if exceed threshold value, will report to the police by alarm module, the light system that ensures realizes normal.
Preferably, described video monitoring function mainly comprises video acquisition function, video compression and memory function, video intelligent processing capacity; Video intelligent processing capacity is mainly carried out video tracking function according to observed object features, the movement locus of render target simultaneously, record out the number of times that it occurs at regional, for adding up the action message of observed object within each time period, in the time noting abnormalities state in video identification process, startup alarm module is reported to the police simultaneously.
Preferably, described microwave occurs and measurement function mainly comprises that microwave occurs and two kinds of functions of microwave measurement, carries out microwave on the one hand control according to system configuration information, carries out microwave irradiation experiment; Carry out on the other hand microwave measurement, record measurement result and judge whether to occur monitoring extremely, will notify warning if exceed threshold value.
Further, described monitoring extremely comprise Microwave exposure time power level lower than threshold value, or when non-exposure power level higher than the situation of threshold value.
Preferably, the setting for operating state mark: when system reaches research end time of setting, or receive and manually finish after experiment order, system will quit work, and it is 0 that operating state value of statistical indicant now will be set, represents that normal termination tests.
Preferably, adopt fault tolerant mechanism to carry out whole research, concrete grammar comprises: check operating state mark, value, if this value is 1, represent that this system is that abnormality is resetted by watchdog circuit; Now, first read the current system time or from Network Capture current time, be then transformed into the time point in Set For Current light system, according to the configuration parameter arranging when task, calculate current should in working stage, then continue carry out this workflow; If this value is 0, system wait user carries out human configuration.
With respect to prior art, the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function of the present invention, has following useful technique effect:
1. the mode that adopts automatic control light photograph, realizes the realization of specifying light system in circadian rhythm research process, improves the automation process of experimental study and the precision that light system realizes, and reduces manually-operated complexity simultaneously.
2. automatic acquisition function and the super setting threshold warning function of temperature, humidity, light intensity are provided, at utmost ensure the environmental factor stability of experimental study.
3. in experiment, introduce video monitoring function, not only can improve experimentation record and control mode, and can follow the tracks of target, statistics target is in the information of each defined area.
4. there is automatic microwave measuring function, can tracking test process in ambient electromagnetic field, contribute to interpretation.
5. the control function of timing microwave irradiation is provided, can carries out automatically timing Microwave exposure, contribute to the research on the impact of biological function circadian rhythm about Microwave exposure.
6. good fault tolerant mechanism, after system runs into and extremely restarts, can proceed experiment according to abnormal front operating state.
Brief description of the drawings
Fig. 1 is a kind of schematic flow sheet of carrying out the method for circadian rhythm research under Microwave exposure with video monitoring function of the present invention.
Embodiment
Describe the architecture of carrying out the method for circadian rhythm research under Microwave exposure with video monitoring function of the present invention in detail below in conjunction with accompanying drawing, but be not construed as limiting the invention.
System design scheme shown in main employing Fig. 1, the function that user needs by user interface (keyboard, mouse, touch-screen or numerical key, network interface etc.) configuration-system, mainly comprises that temperature, humidity and intensity collection cycle and alarm door limit value, illumination light set up to put (as 12LD light system hockets and turns on light and turn off the light operation for every 12 hours), microwave irradiation parameter (under the LD light system of setting, irradiating initial time, irradiation duration, irradiating microwaves frequency, intensity, delayed startup number of days etc.) etc.In system, each functional independence operation, for example, in the time starting to test, the LD light system that adapts to set that need to breed experimental animals is set up stable circadian rhythm, now can not start microwave irradiation module.In the time requiring to start animal used as test to carry out microwave irradiation, restart microwave irradiation function.Attention: the support of microwave irradiation function manually manually boots, but general selection arranges delayed startup parameter delayed startup mode, and which time alignment is more accurate.
Start after experiment control function, temperature, humidity, intensity collection module are carried out the periodicity collection of temperature, humidity, light intensity, and judge according to the threshold value arranging.If the temperature, humidity or the light intensity data that gather exceed the threshold value of its setting, system will be reported to the police by alarm module, and it is for future reference to treat to record warning message.Video monitoring module is mainly carried out video monitoring function, and monitor video is shown, compresses, stored.In video monitoring process, this module will be carried out video tracking function according to animal used as test feature, and the movement locus of render target simultaneously, records out the number of times that it occurs at regional, for adding up the action message of animal used as test within each time period.When the situation that notes abnormalities in video identification process (as animal such as baits at the abnormal state), also startup alarm module is reported to the police.In addition, adopting video mode to carry out omnidistance record to experiment is also a kind of new experimentation record and control form.
In system, microwave module is set and is carried out work according to system configuration module.In the time manually starting this module or delay time and finish, this module (initial time and duration setting) in the operating time section of setting starts microwave irradiation.Wherein reception antenna is positioned at mouse cage bottom, for measuring the microwave power (measuring irradiation power when Microwave exposure, At All Other Times microwave power in testing environment) of this position.Attention: if the microwave power too high (exceeding the threshold value of setting) receiving in non-irradiation time, this module also can notify alarm module to report to the police.
1. one kind has the software design scheme of carrying out the method for circadian rhythm research under Microwave exposure of video monitoring function
After initialization system, first check it is whether to be started by the watchdog circuit reset causing that resets, the main method adopting is the value of inspection operating state sign of flag _ Working, if this value is 1, judgement system is resetted by watchdog circuit.Now, first read the current system time (or from Network Capture current time), then be transformed into the time point in Set For Current light system (as 12LD light system), the configuration parameter arranging according to this task, calculate current should in working stage, then continue carry out this workflow.Adopt this fault-tolerant way, the system that can ensure can be carried out according to former execution flow process after restarted by external interference, and error is dropped to minimum point.If normal start-up routine, the human configuration at system wait man-machine interactively interface.When receiving after the order of starting working, the value that first Flag_Working is set is 0, then the following functional module of executed in parallel:
Temperature acquisition function: periodically record temperature information, and judge whether to exceed threshold range.If gone beyond the scope, will notify alarm module to report to the police.
Humidity collection function: periodically record humidity information, and judge whether to exceed threshold range.If gone beyond the scope, will notify alarm module to report to the police.
Intensity collection function: periodically record intensity signal, and judge whether to exceed threshold range.If gone beyond the scope, will notify alarm module to report to the police.
Video monitoring function: gather the video of tested animal, and carry out target following according to target signature, the information in each region appears in statistics target.Compressed video, and store video simultaneously, files for record and the process control of experimentation.In the time abnormal generation having been detected in video, notice alarm module is reported to the police.
Illumination control function: according to light configuration information processed by the illumination control circuit illumination work that property was turned on light, turned off the light performance period.
Microwave measurement function: according to configuration information, global timing is measured microwave power, records microwave power information, the power level while comprising Microwave exposure.If monitoring abnormal (when Microwave exposure power level lower than threshold value, or when non-exposure power level higher than threshold value) time, notice alarm module is reported to the police.
Microwave generating function: this module is according to system configuration information, and from the exposure initial time of setting, the microwave signal of carrying out setpoint frequency and power level during the exposure duration of setting occurs, structure Microwave exposure environment.
Warning function: detect and whether receive the information that requires warning, if there is the request of warning, starts alarm module and report to the police.
Each functional module is by system configuration information control, can be independently, parallel running.User can configure and whether enable corresponding function as required, and as forbidden, microwave occurs and microwave measurement function is carried out the biological circadian rhythm research under non-Microwave exposure.
When system reaches the operating time (experiment number of days setting) of setting, or receive and manually finish after experiment order, system will quit work, and it is 0 that Flag_Working value now will be set, and expression normal termination is tested.
2. one kind has the hardware scheme of carrying out the method for circadian rhythm research under Microwave exposure of video monitoring function
In order to improve video processing function, whole system adopts multiprocessor working method, one of them primary processor control whole system operation, a video processor is mainly for the treatment of video, it is mutual that two processors carry out video data by the mode of RAM Shared, carry out corresponding Video processing by primary processor by video processing function calling interface notice video processor, and video processor display video (optional), and transmit result and video data to primary processor by RAM Shared, primary processor is to the result receiving and compressed video is stored or or Internet Transmission.Primary processor is connected with temperature, humidity, light intensity sensor by serial ports or I2C interface, requires to carry out collection and the storage of temperature, humidity, light intensity data according to system configuration, can judge whether sampled value exceedes the threshold value of setting simultaneously.If exceed threshold value, system will be reported to the police by IO interface notice alarm module, also carry out network alarming by LAN interface simultaneously.System does not provide wireless communication interface in the time being configured to Microwave exposure mode of operation, prevents that radio communication from producing the interference of microwave to whole experimental situation.This system adopts USB interface to connect mouse, keyboard, adopts touch-screen and numeric keypad etc. to carry out man-machine interaction, also supports to carry out man-machine interaction by network.
This system is supported two kinds of mode control microwaves.A kind of mode is to adopt existing microwave source instrument and microwave measuring instrument, by network using LXI standard, microwave equipment is carried out automatically controlling and automatically measuring, and can make full use of existing microwave precision instrument.Another kind of mode is integrated micro circuit for generating and microwave measurement circuit in system, can be according to the microwave signal (going out by aerial radiation) of the information control microwave circuit for generating launch requirements of configuration, utilize reception antenna to receive microwave signal simultaneously and realize microwave intensity measurement.Attention: two kinds of modes can co-operation, can be by microwave transmitting and microwave measurement function cross-application in two kinds of modes.
This system provides watchdog function, in the time of system exception by rerun routine.Because configuration information has been stored in system, whether system will be determined at present in experimental period according to configuration information.If in experimental period, will obtain current time by network (or system), and definite current system should in operating state, then continue operation, will extremely drop to minimum.
Above-described embodiment is just to allow one of ordinary skilled in the art can understand content of the present invention and implement according to this for technical conceive of the present invention and feature being described, its objective is, can not limit the scope of the invention with this.Every equivalent variation or modification that according to the present invention, the essence of content has been done, all should be encompassed in protection scope of the present invention.
Claims (9)
1. there is the method for carrying out circadian rhythm research under Microwave exposure of video monitoring function, it is characterized in that, comprise a main configuration illumination control function, temperature, humidity and intensity collection function, video monitoring function, the system of warning function and microwave generation and these functional modules of measurement function, the course of work of whole system is as follows: be normal start-up routine, the human configuration at system wait man-machine interactively interface; When receiving after the order of starting working, the value that first operating state mark is set is 0, the task that then functional module described in executed in parallel system is set.
2. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, is characterized in that, described illumination control function is mainly carried out illumination control according to light configuration information processed, simulates illumination rule round the clock.
3. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, it is characterized in that, described temperature, humidity collection function mainly carried out periodically collection and the record of temperature, humidity, the variation of monitoring experiment ambient temperature, humidity; If temperature, humidity exceed threshold value, will report to the police by alarm module, ensure that experiment is not acted upon by temperature changes.
4. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, is characterized in that, described intensity collection function is mainly carried out periodic intensity collection and record, the variation of monitoring experiment environmental light intensity; According to light configuration information processed, monitor whether the light intensity of experimental situation exceeds threshold values or the threshold value of this light intensity, if exceed threshold value, will report to the police by alarm module, the light system that ensures realizes normal.
5. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, it is characterized in that, described video monitoring function mainly comprises video acquisition function, video compression and memory function, video intelligent processing capacity; Video intelligent processing capacity is mainly carried out video tracking function according to observed object features, the movement locus of render target simultaneously, record out the number of times that it occurs at regional, for adding up the action message of observed object within each time period, in the time noting abnormalities state in video identification process, startup alarm module is reported to the police simultaneously.
6. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, it is characterized in that, described microwave occurs and measurement function mainly comprises that microwave occurs and two kinds of functions of microwave measurement, carry out microwave according to system configuration information on the one hand and control, carry out microwave irradiation experiment; Carry out on the other hand microwave measurement, record measurement result and judge whether to occur monitoring extremely, will notify warning if exceed threshold value.
7. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 6, it is characterized in that, described monitoring extremely comprise Microwave exposure time power level lower than threshold value, or when non-exposure power level higher than the situation of threshold value.
8. the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function according to claim 1, it is characterized in that, setting for operating state mark: when system reaches research end time of setting, or receive and manually finish after experiment order, system will quit work, it is 0 that operating state value of statistical indicant now will be set, and represents normal termination experiment.
9. according to the method for carrying out circadian rhythm research under Microwave exposure with video monitoring function described in claim 1 or 8, it is characterized in that, adopt fault tolerant mechanism to carry out whole research, concrete grammar comprises: the value that checks operating state mark, if this value is 1, represent that this system is that abnormality is resetted by watchdog circuit; Now, first read the current system time or from Network Capture current time, be then transformed into the time point in Set For Current light system, according to the configuration parameter arranging when task, calculate current should in working stage, then continue carry out this workflow; If this value is 0, system wait user carries out human configuration.
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