CN103211957B - Alcohol relieving and liver protecting composition and application thereof - Google Patents
Alcohol relieving and liver protecting composition and application thereof Download PDFInfo
- Publication number
- CN103211957B CN103211957B CN201310157072.2A CN201310157072A CN103211957B CN 103211957 B CN103211957 B CN 103211957B CN 201310157072 A CN201310157072 A CN 201310157072A CN 103211957 B CN103211957 B CN 103211957B
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- liver
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- bulbus allii
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- protecting
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- 239000000203 mixture Substances 0.000 title claims abstract description 38
- 210000004185 liver Anatomy 0.000 title claims abstract description 33
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title claims abstract description 27
- 230000002633 protecting effect Effects 0.000 title claims abstract description 23
- RXUWDKBZZLIASQ-UHFFFAOYSA-N Puerarin Natural products OCC1OC(Oc2c(O)cc(O)c3C(=O)C(=COc23)c4ccc(O)cc4)C(O)C(O)C1O RXUWDKBZZLIASQ-UHFFFAOYSA-N 0.000 claims abstract description 16
- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 claims abstract description 16
- 239000003814 drug Substances 0.000 claims abstract description 14
- 231100000753 hepatic injury Toxicity 0.000 claims abstract description 12
- 206010067125 Liver injury Diseases 0.000 claims abstract description 3
- 208000007848 Alcoholism Diseases 0.000 claims description 26
- 201000007930 alcohol dependence Diseases 0.000 claims description 26
- 239000002775 capsule Substances 0.000 claims description 8
- 238000002481 ethanol extraction Methods 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000002671 adjuvant Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 17
- 239000002994 raw material Substances 0.000 abstract description 5
- 240000002234 Allium sativum Species 0.000 abstract description 4
- 235000004611 garlic Nutrition 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 2
- 239000000469 ethanolic extract Substances 0.000 abstract 1
- 239000012467 final product Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 241000699670 Mus sp. Species 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 238000010998 test method Methods 0.000 description 5
- 238000000605 extraction Methods 0.000 description 4
- 230000037396 body weight Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000003304 gavage Methods 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 208000005584 Alcoholic Intoxication Diseases 0.000 description 2
- 241001529936 Murinae Species 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 210000005228 liver tissue Anatomy 0.000 description 2
- 239000013642 negative control Substances 0.000 description 2
- 239000000902 placebo Substances 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 241000234282 Allium Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000222336 Ganoderma Species 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 244000046146 Pueraria lobata Species 0.000 description 1
- 235000010575 Pueraria lobata Nutrition 0.000 description 1
- 240000006394 Sorghum bicolor Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000003673 groundwater Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- HBYYJIPCYANMBX-BAOOBMCLSA-M sodium;[(3s,4r,5r)-3,4,5-trihydroxy-2-oxo-6-phosphonooxyhexyl] hydrogen phosphate Chemical compound [Na+].OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)COP(O)([O-])=O HBYYJIPCYANMBX-BAOOBMCLSA-M 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310157072.2A CN103211957B (en) | 2013-05-02 | 2013-05-02 | Alcohol relieving and liver protecting composition and application thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310157072.2A CN103211957B (en) | 2013-05-02 | 2013-05-02 | Alcohol relieving and liver protecting composition and application thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103211957A CN103211957A (en) | 2013-07-24 |
CN103211957B true CN103211957B (en) | 2015-01-28 |
Family
ID=48810343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201310157072.2A Expired - Fee Related CN103211957B (en) | 2013-05-02 | 2013-05-02 | Alcohol relieving and liver protecting composition and application thereof |
Country Status (1)
Country | Link |
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CN (1) | CN103211957B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106109873A (en) * | 2016-07-22 | 2016-11-16 | 赵月 | Liver-protecting combination is used for the application preventing or treating in the medicine of fatty liver in preparation |
CN107509907A (en) * | 2017-10-18 | 2017-12-26 | 山西琪尔康翅果生物制品有限公司 | A kind of solid beverage with preventing alcoholic liver injury |
CN108464996A (en) * | 2018-04-28 | 2018-08-31 | 乌林奇 | A kind of targeting adjusts pharmaceutical composition and its application of gene |
CN108421027A (en) * | 2018-05-07 | 2018-08-21 | 深圳润邦之家生物科技有限公司 | A kind of relieving alcoholism and protecting liver product |
-
2013
- 2013-05-02 CN CN201310157072.2A patent/CN103211957B/en not_active Expired - Fee Related
Non-Patent Citations (2)
Title |
---|
《大蒜油与大蒜素对急性乙醇性肝损伤预防作用比较》;曾涛;《毒理学杂志》;20080630;第22卷(第3期);197-198 * |
《葛根解酒含片的开发研制》;常亮等;《食品工业》;20101231(第1期);24-25 * |
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CN103211957A (en) | 2013-07-24 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: DU ZHENGQIANG Free format text: FORMER OWNER: ZHAO YUE Effective date: 20141218 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Du Zhengqiang Inventor after: Sun Juping Inventor before: Zhao Yue |
|
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 610066 CHENGDU, SICHUAN PROVINCE TO: 266011 QINGDAO, SHANDONG PROVINCE Free format text: CORRECT: INVENTOR; FROM: ZHAO YUE TO: DU ZHENGQIANG SUN JUPING |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20141218 Address after: 266011 Department of general medicine, Qingdao municipal hospital, 1 Jiaozhou Road, Shandong, Qingdao, China Applicant after: Du Zhengqiang Address before: 610066 Sichuan city of Chengdu province Jinjiang District Temple Road No. 22 Building 1, unit 5, No. 505 Applicant before: Zhao Yue |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150128 Termination date: 20170502 |
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CF01 | Termination of patent right due to non-payment of annual fee |