CN103194341B - Low-irritation baical skullcap root skin care soap - Google Patents
Low-irritation baical skullcap root skin care soap Download PDFInfo
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- CN103194341B CN103194341B CN201310149027.2A CN201310149027A CN103194341B CN 103194341 B CN103194341 B CN 103194341B CN 201310149027 A CN201310149027 A CN 201310149027A CN 103194341 B CN103194341 B CN 103194341B
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Abstract
The invention discloses a low-irritation baical skullcap root skin care soap. The soap comprises the following raw materials in parts by weight: 0.05-0.15 part of baical skullcap root extract, 15-25 parts of sodium cocoate, 50-70 parts of sodium palmitate, 3-5 parts of N-oleoyl-N-sodium methyl taurate, 3-5 parts of olivamidopropylamine oxide and 20 parts of water. The low-irritation baical skullcap root skin care soap is exquisite and stable in foam, has mild properties and low skin irritation and can further moisten and protect the skin especially after the baical skullcap root extract is added.
Description
Technical field:
The present invention relates to a kind of perfumed soap, particularly a kind of Low-irritation baical skullcap root skin care soap.
Background technology:
Perfumed soap (soap) is one of skin, hair washing and nursing article, is a kind of daily necessities.Perfumed soap is with sodium soap and other tensio-active agents for main raw material, adds quality improver and appearance modifying agents, the product made after machine-shaping.
Perfumed soap is requisite washing and nursing article in daily life, with sodium soap and other tensio-active agents for main raw material, adds quality improver and appearance modifying agents, the product made after machine-shaping.The function of perfumed soap is clean washing, to be used in above skin that yes removes earth dirt, skin secretion, movement, chemical substance or bacterium etc., in the today stressing cosmetic result, removing the makeup of skin surface, skin care products or medicine is also one of its main purposes.
In the prior art, the Cake-shape soap of the many insights of perfumed soap to be fatty acid sodium salt be soap base, although have good cleaning force, whipability and easy washability, but not resistance to hard water, can produce incrustation scale during washing, form calcium magnesium soap, degreasing power is strong, the soap of human body life-time service meta-alkalescence can make skin feel dry and astringent, has excitement.
The root of large-flowered skullcap another name Radix Scutellariae, tsuchikane tea root.For the labiate root of large-flowered skullcap (Scutellaria baicalensis Georgi), be used as medicine with root.Have heat-clearing and damp-drying drug, cool blood is antiabortive, detoxicating functions.Cure mainly febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, threatened abortion, hypertension, carbuncle swell the diseases such as furuncle sore.
The pharmacological action of the root of large-flowered skullcap
1. the pharmacological action relevant to effect
(1) antibacterial, antiviral
1. scutellarin, wogonin.
2. external: to have restraining effect to multiple gram positive organism, gram-negative bacteria, pathogenic dermatophytes.
3. antiviral: to suppress influenza virus, hepatitis B virus.
(2) anti-inflammatory
Scutellarin, baicalin → suppression acute inflammatory reaction.Inflammation-inhibiting model oozes out swelling, capillary permeability increases; Suppress rat assist agent arthritis.
1) mechanism: suppress inflammatory mediator to produce, discharge.
2) histamine release is suppressed
3) anti-arachidonic acid metabolism, suppresses the generation of PGE (PGE), leukotrienes (LT), alleviates inflammatory mediator vasodilation, increases Vascular Permeability, leukocytic chemotaxis.
(3) on the impact of immunologic function
Immunosuppression reacts: especially to I allergic reaction type (anaphylaxis) effect significantly.
Effect link:
1. stablize mast cell membrane, reduce inflammatory mediator release.
2. affect arachidonic acid metabolism, suppress the generation of inflammatory mediator.
Improve body's immunity: baicalin, improve scavenger cell, NK cell function.
(4) antipyretic.
(5) protect the liver, cholagogic (clearing liver courage): protect the liver: damage relevant with antioxidant radical.
(6) calm: CNS inhibition.
(7) blood system is affected
Effect is complicated: scutellarin etc. → anticoagulant; Scutellarin etc. → anticoagulation: the scleroproein of anticoagulant enzyme induction produces.
Brief summary:
Antipathogen, anti-inflammatory, immunity moderation function, antipyretic, calm, protect the liver, cholagogic etc.Without antitumor action.
2. other pharmacological actions
(1) reducing blood-fat, atherosclerosis
Flavones ingredient.Reduce serum total cholesterol (TC), reduce serum triglyceride (TG) content, increasing serum high density lipoprotein cholesterol (HDL-C); Atherosclerosis.
(2) antioxidant radical damage: the generation suppressing lipid peroxide (LPO), scavenging free radicals.
(3) step-down: directly expand peripheral blood vessel; Suppress vasomotor center.
Modern study proves, the root of large-flowered skullcap mainly contains baicaline, scutellarin, wogonin, the compositions such as Wogonoside, neobaicalein, β-sitosterol.Its antimicrobial spectrum is comparatively wide, has restraining effect to various bacteria, dermatophytes, Leptospira etc.Even if to the streptococcus aureus that the microbiotic such as penicillin develop immunity to drugs, still very sensitive to the root of large-flowered skullcap.The root of large-flowered skullcap hypotensive, calm, diuresis in addition, protect the liver, cholagogic, antianaphylaxis, the effect such as releasing smooth muscle spasm.Use scutellaria for treating children with acute respiratory infection, infectious hepatitis, chronic tracheitis, acute bacillary dysentery, pyelonephritis etc. clinically, all can obtain good effect.
But, there is not a kind of Traditional Chinese medicine perfumed soap, containing ingredients of Scutellaria.
Summary of the invention:
For prior art above shortcomings, technical problem to be solved by this invention is to provide a kind of Low-irritation baical skullcap root skin care soap.
Technical problem of the present invention, is achieved by following technical proposals:
A kind of Low-irritation baical skullcap root skin care soap, comprises the raw material of following weight part: Radix Scutellariae extract 0.05-0.15 part, coconut oil sodium 15-25 part; Sodium pentadecanecarboxylate 50-70 part; N-oleoyl-N methyl taurine sodium 3-5 part, olivamidopropyl propylamine oxide compound 3-5 part, 20 parts, water.
Preferably; a kind of Low-irritation baical skullcap root skin care soap; comprise the raw material of following weight part: Radix Scutellariae extract 0.05-0.15 part; sequestrant 0.5-1.5 part; N-oleoyl-N methyl taurine sodium 3-5 part, olivamidopropyl propylamine oxide compound 3-5 part, coconut oil sodium 15-25 part; Sodium pentadecanecarboxylate 50-70 part, 20 parts, water.
Described sequestrant, is made up of by weight following component: methyl-glycine diacetate tri-sodium 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
Below, simple declaration is made to part material involved in the present invention:
Radix Scutellariae extract of the present invention can pass through commercially available and obtain, as the Radix Scutellariae extract that Shenzhen BoDun spice Co., Ltd produces.This Radix Scutellariae extract also can adopt following method prepare and obtain: after the root of large-flowered skullcap is pulverized, add the deionized water of 6-10 times of weight, soak 1-3 hour, ultrasonic extraction 10-15 minute, filter, centrifugal, discard precipitation by supernatant concentration, obtained Radix Scutellariae extract, controls Radix Scutellariae extract density at 1.05g/cm
3left and right.
N-oleoyl-N methyl taurine sodium, CAS accession number: 137-20-2.
Olivamidopropyl propylamine oxide compound, CAS accession number: 124046-32-8.
Described methyl-glycine diacetate tri-sodium, CAS accession number: 170492-24-7, its English name: L-Alanine, N, N-bis (carboxymethyl)-, sodium salt (1:3).It has better biological degradability than conventional sequestrant EDTA, NTA, and under wider PH scope and high temperature, more stable, have higher calcium sequestration capacity, and have higher solubility property to inorganic sediment, heavy metal has good sequestering power.Select the Trilon that BASF AG produces in the present invention
m liquid.
Described hydroxyethyl diamine tetraacethyl trisodium salt, CAS accession number: 207386-87-6, its English name: Glycine, N-[2-[bis (carboxymethyl) amino] ethyl]-N-(2-hydroxyethyl)-, trisodium salt, hydrate (9CI).
In addition, in the present invention, other functional ingredient conventional in conventional toilet soaps can also be added, such as: antiseptic-germicide, pigment, essence, oxidation inhibitor, titanium dioxide etc., to realize corresponding function respectively.As added antiseptic-germicide, the antioxidant of 0.05-0.20 weight part, the sanitas of 0.02-0.2 weight part of 0.2-0.8 weight part on formula basis of the present invention, the essence of the titanium dioxide of 0.02-2 weight part, the white dyes of 0.001-0.05 weight part or 0.2-1.2 weight part.
Low-irritation baical skullcap root skin care soap of the present invention can adopt the general soapmaking step of industry conventional toilet soaps to be prepared, as:
A () kneads spice: taken in proportion in the kneading machine joining conventional soapmaking by the various raw materials of said components, knead and be uniformly mixed.
B () grinds: the material after being uniformly mixed kneading, enters in shredder, carries out soap body grinding.
(c) vacuum press strip: by the soap body after grinding, enter vacuum plodder, carry out vacuum press strip.
D () prints: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains shaping soap body.
Low-irritation baical skullcap root skin care soap of the present invention, foam exquisiteness is stable, and performance is gentle, low to the pungency of skin, after special interpolation Radix Scutellariae extract, more can moisten and protect skin.
Embodiment:
Embodiment further illustrates of the present invention below, instead of limit the scope of the invention.In the present invention, if no special instructions, each raw material all in working substance content for 100%.
Embodiment 1
Each raw material is taken by embodiment 1 data of table 1 correspondence.
A () kneads spice: joined in soap kneading machine by various raw material, knead and be uniformly mixed.
B () grinds: the material after being uniformly mixed kneading, enters in shredder, carries out soap body grinding.
(c) vacuum press strip: by the soap body after grinding, enter vacuum plodder, carry out vacuum press strip.
D () prints: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains shaping soap body.
Embodiment 2
Each raw material is taken by embodiment 2 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Embodiment 3
Each raw material is taken by embodiment 3 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Embodiment 4
Each raw material is taken by embodiment 4 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Comparative example 1
Each raw material is taken by comparative example 1 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Table 1: fancy soap formula list position: kilogram
| ? | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Comparative example 1 |
| Radix Scutellariae extract | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| Coconut oil sodium | 20 | 20 | 20 | 20 | 20 |
| Sodium pentadecanecarboxylate | 60 | 60 | 60 | 60 | 60 |
| N-oleoyl-N methyl taurine sodium | 4 | 4 | 4 | 4 | / |
| Olivamidopropyl propylamine oxide compound | 4 | 4 | 4 | 4 | / |
| Methyl-glycine diacetate tri-sodium | / | 1 | / | 0.5 | / |
| Hydroxyethyl diamine tetraacethyl trisodium salt | / | / | 1 | 0.5 | / |
| Water | 20 | 20 | 20 | 20 | 20 |
Test case 1:
Experiment soap lye concentration is 5wt%, and when consumption is 0.3ml, by HET VAM measurements determination skin reaction classification (relative values classification), intense stimulus > 2.0, stimulates 1.2-2.0, medium stimulation 0.8-1.2, minimal irritation 0.0-0.8.
Use Roche Latherometer to carry out foaming properties test, soap lye concentration is 2.5wt%, tests the foam height of 0 minute and 5 minutes respectively.
Table 2: test data table
The test data of experiment of associative list 2, the present invention selects N-oleoyl-N methyl taurine sodium and olivamidopropyl propylamine oxide compound built-up soap fundamental mode anion surfactant coconut oil sodium and Sodium pentadecanecarboxylate initiatively, effectively can reduce the pungency of perfumed soap; Select the composite interpolation of sequestrant methyl-glycine diacetate tri-sodium and hydroxyethyl diamine tetraacethyl trisodium salt initiatively, foaming power and the foam stability of perfumed soap can be promoted further.Above-mentioned difference technical characteristic did not have open in the prior art, was not common practise yet.
Claims (1)
1. a Low-irritation baical skullcap root skin care soap; it is characterized in that; comprise the raw material of following weight part: Radix Scutellariae extract 0.05-0.15 part, sequestrant 0.5-1.5 part, N-oleoyl-N methyl taurine sodium 3-5 part; olivamidopropyl propylamine oxide compound 3-5 part; coconut oil sodium 15-25 part, Sodium pentadecanecarboxylate 50-70 part, 20 parts, water; described sequestrant, is made up of by weight following component: methyl-glycine diacetate tri-sodium 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
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| CN103194341B true CN103194341B (en) | 2014-12-24 |
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| CN107312640A (en) * | 2017-07-05 | 2017-11-03 | 芜湖慧宇商贸有限公司 | A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E |
| CN111449989A (en) * | 2020-05-14 | 2020-07-28 | 上海应用技术大学 | Whitening and moisturizing face cleaning powder and preparation method thereof |
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| US4743395A (en) * | 1986-09-12 | 1988-05-10 | The Drackett Company | Thickened acid cleaner compositions containing quaternary ammonium germicides and having improved thermal stability |
| CN100551244C (en) * | 2006-05-25 | 2009-10-21 | 西安格润森生物制药股份有限公司 | Plant-type antibacterial agent |
| CN102363740B (en) * | 2010-12-10 | 2012-09-12 | 江南大学 | Low-irritation and high-foaminess fancy soap formula |
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Inventor after: Cao Dakang Inventor before: Huang Meirong |
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Effective date of registration: 20171122 Address after: 225000 Guangling District, Yangzhou City, Jiangsu Province, Sha Tau Town Patentee after: The vertical daily use chemicals company limited in Eurasia, Jiangsu Address before: 201604 Shanghai Songjiang District Shihudang mayor road 1000 Lane 2, room 219 Patentee before: Shanghai Bafang Fine Chemical Engineering Co., Ltd. |