CN103187949B - A kind of digital logarithm rectification amplitude extraction wave filter - Google Patents
A kind of digital logarithm rectification amplitude extraction wave filter Download PDFInfo
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- CN103187949B CN103187949B CN201110458231.3A CN201110458231A CN103187949B CN 103187949 B CN103187949 B CN 103187949B CN 201110458231 A CN201110458231 A CN 201110458231A CN 103187949 B CN103187949 B CN 103187949B
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Abstract
The present invention relates to the wave filter of a kind of digital logarithm rectification amplitude extraction, it is characterized in that body surface EEG signals, by signal x (n) of the acquisition wave filter by described digital logarithm rectification amplitude extraction after gathering and compensating, it is thus achieved that amplitude-integrated output signal y (n).Described amplitude-integrated output signal y (n) is:<maths num=" 0001 "></maths>in formula: y (n) be the amplitude-integrated signal after numeral rectification, x (n) be the signal after CFM compensation filter, Cj be correction parameter, fs be the sample frequency of x (n), f0 be the sample frequency of y (n), d (i) be the unit impact response of a kind of ideal capacitance.Fs and f0 takes 400Hz, d (i) when being hamming window function, and sampled and after compensating body surface brain signal carries out amplitude extraction and obtains the amplitude-integrated EEG signals of semilog.Big in the change amplitude of signal, the occasion that amplitude extraction resolution is high, the digital logarithm rectification amplitude that the present invention provides all can obtain good effect, it is adaptable to the digital filter of Digital signal processing.
Description
Technical field
The present invention relates to a kind of digital logarithm rectification amplitude extraction wave filter, it is adaptable to the digital filter of Digital signal processing, it is adaptable to research and development and Medical Instruments.Belong to CFM filter field.
Background technology
For many years, the death of brain injury always neonatal period and the main reason disabled.Within 2004, Ministry of Public Health statistical data shows, death causes of newborn infants is suffocated in constituting and complication accounts for 26.5%, and row rank first.It addition, brain injury of preterm infants (including that intracranial hemorrhage and periventricular white matter soften) is also the major reason causing children cerebral palsy and mental retardation.Therefore the early diagnosis research of Neonatal Brain Damage, and carry out Neonatal Brain Damage examination the most in China, the population improving China there is is very important realistic meaning with health level.
Amplitude-integrated cerebral function monitoring has extremely important effect to early discovery and the examination of Neonatal Brain Damage, the monitoring of digital amplitude-integrated cerebral function is different from traditional brain electricity, its mechanism does not also lie in the electroencephalogram waveform in concrete a certain moment, and is long variation tendency.Since external proposition amplitude-integrated brain this new signal processing method of electricity, the states such as USA and Europe all strengthen the research to this medical domain, starting late of domestic Amplitude integrated electroencephalogram, professor Shao Xiaomei etc. of one of present invention applicant Children's Hospital, Fudan University takes the lead in starting to study neonatal amplitude-integrated brain electricity in late 1990s.The national multiple center clinical study result carried out shows, the amplitude-integrated cerebral function monitoring with continuous multi-faceted monitoring in 24 hours has good effect in Neonatal Brain Damage diagnoses.This research is one of clinical multicenter study that at present 3 sample sizes are maximum the most in the world, is also the only one research that represents asian population feature.
Amplitude-integrated cerebral function is guarded, main sampling body surface EEG signals, after signal processing, extracts the amplitude variations of signal, carries out record.Have conveniently, safely, accurately, be susceptible to the advantages such as interference.Through amplifying, sampling, after CFM compensation filter, signal is made amplitude extraction, semilogization compression could obtain amplitude-integrated brain wave patterns for diagnosing.The robustness of amplitude extraction algorithm, capacity of resisting disturbance, adaptability have impact on the performance of amplitude-integrated cerebral function monitor device to a great extent.Owing to body surface EEG signals is the faintest, in amplifying gatherer process, it is easily introduced bigger noise；It is difficult to control to additionally, due to behaviors such as neonatal limb motions, sampling process is also easily introduced the multiple interference such as drift, myoelectricity.Traditional rectification module is made up of diode, electric capacity or its equivalent circuit, uses simulation rectification module can extract amplitude signal to after the signal amplification of 5-250 microvolt.But simulation rectification module has the shortcoming that temperature drift greatly, is easily disturbed, so most electroencephalograph is required to use in shielding machine room, it is desirable to experimenter loosens, is in sleep or half asleep.If using simulation commutation technique, being on a grand scale of circuit, cost is high, poor reliability, and the limitation that the application of simulation commutation technique is subject to more is the biggest.So the rectification module of necessary abandoning tradition and the method for rectifying of simulation rectification module, intend the wave filter of the new rectification amplitude extraction of a kind of digital logarithm of offer, to meet the requirement that neonate uses, thus be guided out the design of the application.
Summary of the invention
It is an object of the invention to provide a kind of digital logarithm rectification amplitude extraction wave filter, namely the present invention describes a kind of digital filter that may be used for the extraction of amplitude-integrated brain wave patterns.For the patient mainly for this specific group of neonate, its state is wayward, add the requirement of 24 hours on-line monitors, require to depart from shielding machine room, and can use in normal circumstances, the structure of digital logarithm rectification amplitude extraction wave filter is as it is shown in figure 1, the EEG signals of patient body-surface, by signal x (n) of acquisition after gathering and compensating by digital logarithm rectification amplitude extraction wave filter described in the invention, it is possible to obtain amplitude-integrated signal y (n).The process obtained is as follows:
In formula: y (n) is the amplitude-integrated signal after numeral rectification
X (n) is the signal after CFM compensation filter
Cj is correction parameter
Fs is the sample frequency of x (n)
F0 is the sample frequency of y (n)
D (i) is the unit impact response of a kind of ideal capacitance
Y (n) obtains amplitude-integrated signal after f0 resampling, obtains amplitude-integrated EEG signals through incomplete logarithm process
Z (n)=alog [y (n)] y (n) ＞ 5 μ V
Z (n)=ay (n) y (n)≤5 μ V
Big in the change amplitude of signal, the occasion that amplitude extraction resolution is high, digital logarithm rectification amplitude extraction algorithm can obtain good effect, it is adaptable to the digital filter of Digital signal processing, is particularly suited for the requirement that neonate uses.
Accompanying drawing explanation
The logarithm numeral rectification schematic diagram that Fig. 1 provides for the present invention.
Fig. 2 is the structure of filtering algorithm of the present invention.
Detailed description of the invention
Digital logarithm rectification amplitude extraction wave filter can be applied in various instruments.Below in conjunction with specific embodiment, the present invention will be further described, it should clear that following is an explanation to the present invention, and should not be considered as limitation of the invention.
The step of the digital logarithm rectification amplitude extraction that the present invention provides is body surface EEG signals as shown in Figure 1, by signal x (n) of the acquisition wave filter by described digital logarithm rectification amplitude extraction after gathering and compensating, it is thus achieved that amplitude-integrated output signal y (n).
And for example Fig. 2 is the schematic diagram to amplitude-integrated output signal filtering algorithm structure.
As a example by amplitude-integrated cerebral function is guarded, fs and f0 all takes 400Hz, d (i) and takes hamming window function, the body surface EEG signals after over-sampling, compensation is carried out amplitude extraction and just can obtain the amplitude-integrated EEG signals of semilog.Certainly, suitably adjusting d (i) by experiment and clinical verification and C (j) curve can realize more preferable amplitude extraction effect, wave filter of the present invention achieves good effect in clinical practice.
Claims (4)
1. a digital logarithm rectification amplitude extraction wave filter, it is characterized in that body surface EEG signals, by signal x (n) of acquisition after gathering and compensating by described digital logarithm rectification amplitude extraction wave filter, it is thus achieved that amplitude-integrated output signal y (n)
In formula: y (n) is the amplitude-integrated signal after numeral rectification,
X (n) is the signal after CFM compensation filter,
Cj is correction parameter,
Fs is the sample frequency of x (n),
F0 is the sample frequency of y (n),
D (i) is the unit impact response of a kind of ideal capacitance.
2. the wave filter as described in claim 1, it is characterised in that described y (n) obtains amplitude-integrated signal after f0 resampling, obtains amplitude-integrated EEG signals z (n) through incomplete logarithm process and is expressed as:
A) z (n)=alog [y (n)] y (n) > 5 μ V,
B) z (n)=ay (n) y (n)≤5 μ V,
In formula, a is correction coefficient.
3. the wave filter as described in claim 1, it is characterised in that fs and f0 takes 400Hz, d (i) when being hamming window function, sampled and after compensating body surface brain signal carries out amplitude extraction and obtains the amplitude-integrated EEG signals of semilog.
4. the wave filter as described in claim 1, it is characterised in that adjust d (i) and Cj curve obtains more preferable amplitude extraction effect.
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| CN1649448A (en) * | 2003-11-28 | 2005-08-03 | 索尼株式会社 | Digital signal processing apparatus, method thereof and headphone apparatus |
| CN101627909A (en) * | 2009-05-05 | 2010-01-20 | 复旦大学附属儿科医院 | Digital amplitude-integrated cerebral function monitor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1649448A (en) * | 2003-11-28 | 2005-08-03 | 索尼株式会社 | Digital signal processing apparatus, method thereof and headphone apparatus |
| CN101627909A (en) * | 2009-05-05 | 2010-01-20 | 复旦大学附属儿科医院 | Digital amplitude-integrated cerebral function monitor |
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