CN103157087A

CN103157087A - Drug for treating femoral head necrosis

Info

Publication number: CN103157087A
Application number: CN2013101111789A
Authority: CN
Inventors: 张国
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-03-22
Filing date: 2013-03-22
Publication date: 2013-06-19

Abstract

The invention relates to a drug for treating femoral head necrosis. The drug is prepared from the following materials in parts by weight: 5-10 parts of radix scrophulariae, 10-20 parts of rhizoma zingiberis, 20-30 parts of dogwood, 10-20 pats of platycodon grandiflorum, 15-25 parts of radix angelicae, 5-15 parts of inula flower, 10-30 parts of cowherb seed, 1-15 parts of herba aristolochiae, 10-20 parts of radices sileris, 15-30 parts of oriental wormwood, 20-30 parts of radix rehmanniae preparata, 1-20 parts of morinda officinalis, 1-20 parts of celandine, 10-25 parts of lalang grass rhizome, 10-30 parts of cocklebur fruit, 1-20 parts of emblic leafflower fruit, 15-20 parts of kamuning, 10-20 parts of paris polyphylla, 15-20 parts of herba inulae, 15-30 parts of glabrous sarcandra herb, 10-20 parts of clinopodium polycephalum, 10-25 parts of arisaema cum bile, 5-15 parts of nelumbium speciosum, 1-20 parts of uniflower swisscentaury root, 15-25 parts of rhododendron dauricum, 15-25 parts of potentilla discolor, 10-20 parts of calyx seu fructus physalis, 15-25 parts of cortex mori radicis, 20-30 parts of lindley eupatorium, 1-20 parts of gorgon fruit and 10-25 parts of chinese azalea flower. All the components of the drug for treating femoral head necrosis in the invention are natural materials, so the drug is good in safety, clear in curative effect and suitable for large-scale promotion clinically.

Description

A kind of medicament for the treatment of femur head necrosis

Technical field

The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of femur head necrosis.

Background technology

Femur head necrosis is the difficult disease that world's orthopaedics is generally acknowledged, its serious harm mankind's health gently makes the people disable, and is heavy the people is paralysed, and loses and works and self care ability.The cause of disease that generally believes femur head necrosis mainly contains: wound, hormone, excessive drinking or osteoporosis etc.Main clinic symptoms is pain and marrow joint movement function obstacle.For this disease, mainly take conservative treatment, late period to adopt artificial replacement's art early stage.Though the scheme interview of multiple treatment femur head necrosis is arranged at present, but exists in various degree the shortcomings such as cost is high, the course for the treatment of is long, side effect is large, curative effect is undesirable.

Summary of the invention

The purpose of this invention is to provide a kind of medicament for the treatment of femur head necrosis.

in order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of femur head necrosis, it is to be made by the material of following weight proportioning: Radix Scrophulariae 5-10 part, Rhizoma Zingiberis 10-20 part, Fructus Corni 20-30 part, Radix Platycodonis 10-20 part, Radix Angelicae Dahuricae 15-25 part, Flos Inulae 5-15 part, Semen Vaccariae 10-30 part, Herba Aristolochiae 1-15 part, Radix Saposhnikoviae 10-20 part, Herba Artemisiae Scopariae 15-30 part, Fructus Terminaliae Billericae 20-30 part, Radix Morindae Officinalis 1-20 part, Herba Chelidonii 1-20 part, Rhizoma Imperatae 10-25 part, Fructus Xanthii 10-30 part, Fructus Phyllanthi 1-20 part, Folium Et Cacumen Murrayae 15-20 part, Rhizoma Paridis 10-20 part, Herba Inulae 15-20 part, Herba Sarcandrae 15-30 part, Herba Clinopodii 10-20 part, Arisaema Cum Bile 10-25 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5-15 part, Radix Rhapontici 1-20 part, Folium Rhododendri Daurici 15-25 part, Herba Potentillae Discoloris 15-25 part, Calyx Seu Fructus Physalis 10-20 part, Cortex Mori 15-25 part, Herba Eupatorii Lindleyani 20-30 part, Semen Euryales 1-20 part and Flos Rhododendri Mollis 10-25 part.

preferably, the medicament for the treatment of femur head necrosis of the present invention is to be made by the material of following weight proportioning: 7 parts of Radix Scrophulariaes, 13 parts of Rhizoma Zingiberiss, 22 parts of Fructus Corni, 15 parts of Radix Platycodoniss, 21 parts of the Radixs Angelicae Dahuricae, 13 parts of Flos Inulaes, 28 parts of Semen Vaccariae, 11 parts of Herba Aristolochiaes, 17 parts of Radix Saposhnikoviaes, 24 parts of Herba Artemisiae Scopariaes, 27 parts of Fructus Terminaliae Billericaees, 18 parts of Radix Morindae Officinaliss, 17 parts of Herba Chelidoniis, 23 parts of Rhizoma Imperataes, 21 parts of Fructus Xanthii, 16 parts of Fructus Phyllanthis, 16 parts of Folium Et Cacumen Murrayae, 17 parts of Rhizoma Paridis, 19 parts of Herba Inulae, 15 parts of Herba Sarcandraes, 14 parts of Herba Clinopodii, 21 parts of Arisaema Cum Bile, 11 parts of Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 13 parts of Radix Rhapontici, 23 parts of Folium Rhododendri Daurici, 24 parts of Herba Potentillae Discoloris, 14 parts of Calyx Seu Fructus Physaliss, 25 parts of Cortex Mori, 26 parts of Herba Eupatorii Lindleyanis, 24 parts of 16 parts of Semen Euryaless and Flos Rhododendri Mollis.

More preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.

Whole compositions of the medicament for the treatment of femur head necrosis of the present invention are all natural materials, and safety is better, and curative effect is clear and definite, are suitable for large-scale promotion clinically.

The specific embodiment

Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for explanation the present invention rather than limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, otherwise the percent in the present invention is percetage by weight.

Embodiment decoction of the present invention

take Radix Scrophulariae 7 grams, Rhizoma Zingiberis 13 grams, Fructus Corni 22 grams, Radix Platycodonis 15 grams, the Radix Angelicae Dahuricae 21 grams, Flos Inulae 13 grams, Semen Vaccariae 28 grams, Herba Aristolochiae 11 grams, Radix Saposhnikoviae 17 grams, Herba Artemisiae Scopariae 24 grams, Fructus Terminaliae Billericae 27 grams, Radix Morindae Officinalis 18 grams, Herba Chelidonii 17 grams, Rhizoma Imperatae 23 grams, Fructus Xanthii 21 grams, Fructus Phyllanthi 16 grams, Folium Et Cacumen Murrayae 16 grams, Rhizoma Paridis 17 grams, Herba Inulae 19 grams, Herba Sarcandrae 15 grams, Herba Clinopodii 14 grams, Arisaema Cum Bile 21 grams, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 11 grams, Radix Rhapontici 13 grams, Folium Rhododendri Daurici 23 grams, Herba Potentillae Discoloris 24 grams, Calyx Seu Fructus Physalis 14 grams, Cortex Mori 25 grams, Herba Eupatorii Lindleyani 26 grams, Semen Euryales 16 grams and Flos Rhododendri Mollis 24 grams, add 2000 milliliters of entry, in being housed, heated 4 hours under 80 ℃ by the flask of condensing tube, filter.Filtrate is concentrated into 600 milliliters, namely gets decoction of the present invention.

Experimental example

One, patient's data

Treat 50 examples, male 25 examples wherein, female's 25 examples, the oldest 59 years old, minimum 33 years old, 42 years old mean age." the disease of tcm Standardization of diagnosis and curative effect " that diagnostic criteria is issued with reference to State Administration of Traditional Chinese Medicine (State Administration of Traditional Chinese Medicine. traditional Chinese medical science disease Standardization of diagnosis and curative effect [S]. Nanjing: publishing house of Nanjing University, 1994:193-195) formulate: 1. obvious hip trauma history is arranged; 2. Long-term Hormone is arranged, excessive drinking history etc. without the hip trauma history; 3. hip pain, take adductor starting point place as main, pain can be persistence or intermittence, and radiating pain is to knee joint downwards; 4. difficulty in walking, be the row of crossing mountains, and carrying out property increases the weight of; 5. the hip joint function obstacle, be limited as the master with the inward turning abduction, and the passive activity hip joint can have the surrounding tissue cramp; 6. x-ray is taken the photograph the collapse of the femoral head of the visible femoral head density change of sheet inspection and middle and late stage.

Two, Therapeutic Method

Use the decoction for preparing in embodiment to treat, every day 2 times, each oral 50 milliliters.Treating 10 days is a course for the treatment of.

Three, efficacy assessment standard

Recovery from illness: walking to be without the row of crossing mountains, and hip joint is without pain, and lower limb are without the secondary cripetura, function fully or basic the recovery, X-ray film femoral head sequestrum district subsides, osteonecrosis and bone regeneration hardening phenomenon disappear substantially; Take a turn for the better: sx↓, the hip joint movable function improves, and the lower limb cripetura is in the 1cm left and right, and it is large or flat that the X-ray film femoral head becomes, but osteonecrosis and bone regeneration hardening phenomenon are improved; Invalid: symptom is without improvement, and X-ray film sign is without improvement.

Four, result

Through the treatment of a course for the treatment of, 50 routine patients' therapeutic effect is recovery from illness,

Five, untoward reaction

Carry out tracing observation for 50 routine patients in therapeutic process, do not find obvious untoward reaction.

Claims

1. medicament for the treatment of femur head necrosis, it is characterized in that, it is to be made by the material of following weight proportioning: Radix Scrophulariae 5-10 part, Rhizoma Zingiberis 10-20 part, Fructus Corni 20-30 part, Radix Platycodonis 10-20 part, Radix Angelicae Dahuricae 15-25 part, Flos Inulae 5-15 part, Semen Vaccariae 10-30 part, Herba Aristolochiae 1-15 part, Radix Saposhnikoviae 10-20 part, Herba Artemisiae Scopariae 15-30 part, Fructus Terminaliae Billericae 20-30 part, Radix Morindae Officinalis 1-20 part, Herba Chelidonii 1-20 part, Rhizoma Imperatae 10-25 part, Fructus Xanthii 10-30 part, Fructus Phyllanthi 1-20 part, Folium Et Cacumen Murrayae 15-20 part, Rhizoma Paridis 10-20 part, Herba Inulae 15-20 part, Herba Sarcandrae 15-30 part, Herba Clinopodii 10-20 part, Arisaema Cum Bile 10-25 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5-15 part, Radix Rhapontici 1-20 part, Folium Rhododendri Daurici 15-25 part, Herba Potentillae Discoloris 15-25 part, Calyx Seu Fructus Physalis 10-20 part, Cortex Mori 15-25 part, Herba Eupatorii Lindleyani 20-30 part, Semen Euryales 1-20 part and Flos Rhododendri Mollis 10-25 part.

2. the medicament for the treatment of femur head necrosis according to claim 1, it is characterized in that, it is to be made by the material of following weight proportioning: 7 parts of Radix Scrophulariaes, 13 parts of Rhizoma Zingiberiss, 22 parts of Fructus Corni, 15 parts of Radix Platycodoniss, 21 parts of the Radixs Angelicae Dahuricae, 13 parts of Flos Inulaes, 28 parts of Semen Vaccariae, 11 parts of Herba Aristolochiaes, 17 parts of Radix Saposhnikoviaes, 24 parts of Herba Artemisiae Scopariaes, 27 parts of Fructus Terminaliae Billericaees, 18 parts of Radix Morindae Officinaliss, 17 parts of Herba Chelidoniis, 23 parts of Rhizoma Imperataes, 21 parts of Fructus Xanthii, 16 parts of Fructus Phyllanthis, 16 parts of Folium Et Cacumen Murrayae, 17 parts of Rhizoma Paridis, 19 parts of Herba Inulae, 15 parts of Herba Sarcandraes, 14 parts of Herba Clinopodii, 21 parts of Arisaema Cum Bile, 11 parts of Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 13 parts of Radix Rhapontici, 23 parts of Folium Rhododendri Daurici, 24 parts of Herba Potentillae Discoloris, 14 parts of Calyx Seu Fructus Physaliss, 25 parts of Cortex Mori, 26 parts of Herba Eupatorii Lindleyanis, 24 parts of 16 parts of Semen Euryaless and Flos Rhododendri Mollis.

3. the medicament for the treatment of femur head necrosis according to claim 1, is characterized in that, described medicament can be tablet, dispersible tablet, capsule or decoction.