CN103156957B - External medicine for treating cervical vertebra and lumbar diseases and arthritis pain and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese medicine and a preparation method thereof, and in particular relates to an external medicine for cervical vertebra and lumbar diseases and arthritis pain. Radix aconiti, asaret, datura flower, borneol, fructus aurantii, ledebouriella root, notoperygium root and the like are prepared into liquid components and paste components according to groups, and when the external medicine is used, the liquid components are sprayed on the paste components. According to the external medicine for treating cervical vertebra and lumbar diseases and arthritis pain, the components are organically combined, the pharmacological action of the components is fully played, and a spray and a paste are organically combined, so that the advantage that the spray can quickly relieve pain is kept, and the drug effect can be prolonged through the paste, the medicinal components can reach focuses, and thus the external medicine has the effect of treating both symptoms and root causes.

Description

Medicine for external use for the treatment of neck and lumbar spondylosis and arthritis ache and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine and preparation method thereof, especially a kind of medicine for external use for the treatment of neck and lumbar spondylosis and arthritis ache.

Background technology

Arthralgia is mainly to cause due to arthritis or arthrosis.It is very extensive and of a great variety that arthralgia involves scope, so the Differential Diagnosis of arthralgia is most important.Arthralgia belongs to the disease categories such as arthrodynia of the extremities, oncotic arthralgia of limbs, arthromyodynia, gout in disease of tcm.In life, a lot of people are subject to the puzzlement of arthralgia.Cause the reason of arthralgia a lot, according to age, sex, outbreak position, symptom characteristic, generally can summarize soft tissue, cartilage, bone and the reason such as struvite.The medicine of existing treatment neck and lumbar spondylosis and arthritis ache can be divided into two kinds of endo-medicine and external used medicines, and endo-medicine side effect is large, to health, can produce various unforeseen negative effects, and the special populations such as athlete will be used especially cautiously; External used medicine mostly adopts the method for spraying, absorbs the object that reaches pain relieving by epidermis, although pain relieving instant effect, side effect are little, because drug volatilization is very fast, often cures the symptoms, not the disease, can only short time pain relieving, cannot eradicate focus.

Summary of the invention

The object of this invention is to provide treatment neck that a kind of lasting medicine, side effect are little and the medicine for external use of lumbar spondylosis and arthritis ache, can not only pain relieving can also fundamentally cure sufferer.

The medicine for external use for the treatment of neck of the present invention and lumbar spondylosis and arthritis ache, it is characterized in that the composition that comprises following parts by weight makes: Radix Aconiti Kusnezoffii 8-10, Herba Asari 8-10, Flos Daturae 5-6, Borneolum Syntheticum 12-16, Fructus Aurantii 6-15, Radix Saposhnikoviae 6-15, Rhizoma Et Radix Notopterygii 3-12, Cortex Lycii 3-10, Radix Salviae Miltiorrhizae 6-15.

Described composition also comprises the component of following parts by weight

Styrax 1-3, Sanguis Draxonis 1-3.

The preparation method of the medicine for external use of above-mentioned treatment neck and lumbar spondylosis and arthritis ache, is characterized in that comprising the steps:

A) prepare medicine liquid ingredient: by the Radix Aconiti Kusnezoffii of above-mentioned weight portion, Herba Asari, Flos Daturae mixed grinding powdering, immerse in the ethanol of 200-400 weight portion; Borneolum Syntheticum immerses in the ethanol of 150-200 weight portion; Described alcohol concentration is 50%, under natural temperature, soaks 7-10 days, and elimination slag is got two kinds of liquid mixing even, obtains medicine liquid ingredient;

B) prepare ointment composition: by each composition mixed grinding powdering of above-mentioned residue, be mixed into mastic with the Oleum sesami of 80-120 weight portion, obtain ointment composition;

C) product is synthetic: adopt aerosol apparatus described medicine liquid ingredient to be sprayed to the medicine for external use that obtains described treatment neck and lumbar spondylosis and arthritis ache on ointment composition.

Radix Aconiti Kusnezoffii is the tuber of Ranunculaceae herbaceos perennial Aconitum carmichjaelii Debx. or Aconitum kusnezoffii Reichb.The effect with expelling wind and removing dampness, antalgic.

Herba Asari is the dry herb of aristolochiaceae plant Herba Asari, Seoul Herba Asari or magnificent Herba Asari.Cure mainly: dispel the wind, cold expelling, row water, has one's ideas straightened out.The traditional Chinese medical science is usually used in treating air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia etc.

Flos Daturae, i.e. Flos Daturae, is again Mandala, completely reaches, Man Zha, Manda, be bent on flower, Canis familiaris L. Semen Juglandis, maple Flos Solani Melongenae, ten thousand Flos persicaes, Flos Rhododendri Mollis, typhon flower, BrachybotryS paridiformis etc.Its leaf, flower, seed is used as medicine and has spasmolytic, calmness, analgesia, the function of anesthesia.Use its dry flower to be used as medicine herein.

Borneolum Syntheticum, has another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., is that resin and the volatile oil processed goods of Spore density Borneolum Syntheticum extracts the crystallization obtaining, and is near pure dextro Borneolum Syntheticum.Also useful chemical method is synthetic.It can be used for for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, for skin infection, swells and ache, and does not hold back etc. after bursting.

Fructus Aurantii is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.The traditional Chinese medical science is usually used in treating that septum pectorale expectorant is let out, trusted subordinate is depressed, and two help axil pain, and dyspepsia does not disappear, and pus and pain etc. disappears.

Radix Saposhnikoviae, another name: Spuropimpinella brachycarpa (Kom.) Kitag., Herba Stenosolenii saxatilis, copper rue, Hui Yun, return grass, Rhizoma Cibotii, hundred fragrant-flowered garlic, hundred kinds, screen, RADIX SAPOSHINOKOVIAE from Northeast, Radix Ligustici Brachylobi, rasix seseli, eastern Radix Saposhnikoviae.It is the dry root of umbelliferae Saposhnikovia divaricata.The traditional Chinese medical science is used as the medicine that induces sweat, dispels the wind.

Rhizoma Et Radix Notopterygii is dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.Cure mainly: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.The effect with loose exterior cold, wind-damp dispelling, sharp joint, pain relieving.

Cortex Lycii, another name: Qi root, bone, auxiliary, save etc.It is the dry root bark of matrimony vine of solanaceae plant or lycium barbarum.There is removing heat from blood except effects such as treasure, lung heat clearing pathogenic fire reducing.

Radix Salviae Miltiorrhizae, has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, Arisaema balansae Engl. etc.For dicotyledon Labiatae, dry root and rhizome.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.

Styrax, another name: Supreme Being's cream, Storax oil, Storax oil, Supreme Being's oil stream.The balsam that the trunk of Hamamelidaceae Plants Styrax tree oozes out, forms through processing and refining.Have and have one's ideas straightened out, ward off effect dirty, pain relieving.

Sanguis Draxonis, another name: black horse Lin exhausts, sea wax, dragon's blood, wooden Sanguis Draxonis.That the resin that oozes out of babassu Sanguis Draxonis fruit is through being processed into.There is promoting blood circulation to remove blood stasis, analgesic therapy, the effect of hemostasia and promoting granulation.

The medicine for external use of this treatment neck and lumbar spondylosis and arthritis ache organically combines above-mentioned various compositions, gives full play to the pharmacological action of various compositions, has the effect in invigorating blood circulation analgesia, wind-damp dispelling, sharp joint.And spray and ointment are organically combined, not only retained the advantage that spray pain relieving is fast but also can extend drug effect by ointment, make ingredient can arrive at focus, play the effect that takes stopgap measures and effect a permanent cure.Selected for 100 example ages did clinical comparison test at 40-50 year fatigability Patients with Cervical Spondylopathy, patient is to bend over one's desk working for a long time and causes cervical vertebra to have pain, feeling of numbness.Choose at random wherein 50 examples and adopt certain brand spray treatment, other 50 examples adopt medicine for external use treatment of the present invention, and clinical observation shows: adopt the patient of spray treatment treatment, medication 1-2 minute is pain relief or disappearance, but second day glucose recovery, medication in continuous a week is not improved; Adopt the patient of medicine for external use treatment of the present invention, medication 1-2 minute is pain relief or disappearance, after continuous use three days, 8 patient's symptoms obviously alleviate, medication has again 15 patient's symptoms obviously to alleviate for six days later, three patient's transference cures wherein, and medication is after ten days, the patient that symptom alleviates reaches 30 people, transference cure have 7 people.

Another experimental group select 40 example ages 40-70 year old Human Osteoarthritis do clinical trial, adopt medicine for external use treatment of the present invention, medication 1-2 minute is pain relief or disappearance, after continuous use three days, 3 patient's symptoms obviously alleviate, and medication has again 3 patient's symptoms obviously to alleviate after the course for the treatment of in six days, three courses for the treatment of of continuous use, all patient's pains disappear, and wherein 29 patient's symptoms alleviate or obviously alleviate, and 11 patients are not improved.

The specific embodiment

Embodiment 1:

Standby medicine, according to following parts by weight for medicine: Radix Aconiti Kusnezoffii 8, Herba Asari 8, Flos Daturae 5, Borneolum Syntheticum 12, Fructus Aurantii 6, Radix Saposhnikoviae 6, Rhizoma Et Radix Notopterygii 3, Cortex Lycii 3, Radix Salviae Miltiorrhizae 6.

Make, make in accordance with the following steps

A) prepare medicine liquid ingredient: by the Radix Aconiti Kusnezoffii of above-mentioned weight portion, Herba Asari, Flos Daturae mixed grinding powdering, immerse in the ethanol of 200 weight portions; Borneolum Syntheticum immerses in the ethanol of 150 weight portions; Described alcohol concentration is 50%, soaks 7 days under natural temperature, and elimination slag, gets two kinds of liquid mixing even, obtains medicine liquid ingredient, and medicine liquid ingredient can pack in Brown Glass Brown glass bottles and jars only to be preserved.

B) prepare ointment composition: by above-mentioned all the other each compositions, be Fructus Aurantii, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Cortex Lycii, Radix Salviae Miltiorrhizae, be mixed in proportion and grind to form powdery, be mixed into mastic with the Oleum sesami of 80 weight portions, obtain ointment composition;

C) product is synthetic: adopt aerosol apparatus described medicine liquid ingredient to be sprayed to the medicine for external use that obtains described treatment neck and lumbar spondylosis and arthritis ache on ointment composition.This step can complete when patient uses, first at disease sites spraying part medicine liquid ingredient, and then ointment composition is applied to disease sites and wraps up with gauze or binder, within 12 hours, on ointment composition, spray again remaining medicine liquid ingredient, keeping 12 hours, totally 24 hours is a medication cycle again.

In addition, as a further improvement on the present invention, can also in ointment composition, add the Styrax of 1 weight portion and the Sanguis Draxonis of 1 weight portion, participate in step B) mixed grinding powdering, then be mixed into mastic with Oleum sesami.

Embodiment 2:

Standby medicine, according to following parts by weight for medicine: Radix Aconiti Kusnezoffii 10, Herba Asari 10, Flos Daturae 6, Borneolum Syntheticum 16, Fructus Aurantii 15, Radix Saposhnikoviae 15, Rhizoma Et Radix Notopterygii 12, Cortex Lycii 10, Radix Salviae Miltiorrhizae 15, Styrax 3, Sanguis Draxonis 3.

Make, make in accordance with the following steps

A) prepare medicine liquid ingredient: by the Radix Aconiti Kusnezoffii of above-mentioned weight portion, Herba Asari, Flos Daturae mixed grinding powdering, immerse in the ethanol of 400 weight portions; Borneolum Syntheticum immerses in the ethanol of 200 weight portions; Described alcohol concentration is 50%, soaks 10 days under natural temperature, and elimination slag, gets two kinds of liquid mixing even, obtains medicine liquid ingredient;

B) prepare ointment composition: by each composition of above-mentioned residue, be that Fructus Aurantii, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Cortex Lycii, Radix Salviae Miltiorrhizae, Styrax, Sanguis Draxonis are mixed in proportion and grind to form powdery, be mixed into mastic with the Oleum sesami of 120 weight portions, obtain ointment composition;

C) product is synthetic: adopt aerosol apparatus described medicine liquid ingredient to be sprayed to the medicine for external use that obtains described treatment neck and lumbar spondylosis and arthritis ache on ointment composition.

All the other are with embodiment 1.

According to different patients' health, the parts by weight of above-mentioned each composition can suitably be adjusted within the specific limits, and its proportioning adjusting range is as follows: Radix Aconiti Kusnezoffii 8-10, Herba Asari 8-10, Flos Daturae 5-6, Borneolum Syntheticum 12-16, Fructus Aurantii 6-15, Radix Saposhnikoviae 6-15, Rhizoma Et Radix Notopterygii 3-12, Cortex Lycii 3-10, Radix Salviae Miltiorrhizae 6-15, Styrax 1-3, Sanguis Draxonis 1-3.

Claims (2)

1. treat the medicine for external use of neck and lumbar spondylosis and arthritis ache, it is characterized in that being made by the composition of following parts by weight: Radix Aconiti Kusnezoffii 8-10, Herba Asari 8-10, Flos Daturae 5-6, Borneolum Syntheticum 12-16, Fructus Aurantii 6-15, Radix Saposhnikoviae 6-15, Rhizoma Et Radix Notopterygii 3-12, Cortex Lycii 3-10, Radix Salviae Miltiorrhizae 6-15, Styrax 1-3, Sanguis Draxonis 1-3.

2. the preparation method of the medicine for external use for the treatment of neck according to claim 1 and lumbar spondylosis and arthritis ache, is characterized in that comprising the steps:

A) prepare medicine liquid ingredient: by the Radix Aconiti Kusnezoffii of above-mentioned weight portion, Herba Asari, Flos Daturae mixed grinding powdering, immerse in the ethanol of 200-400 weight portion; Borneolum Syntheticum immerses in the ethanol of 150-200 weight portion; Described alcohol concentration is 50%, under natural temperature, soaks 7-10 days, and elimination slag is got two kinds of liquid mixing even, obtains medicine liquid ingredient;

B) prepare ointment composition: by each composition mixed grinding powdering of above-mentioned residue, be mixed into mastic with the Oleum sesami of 80-120 weight portion, obtain ointment composition;

C) product is synthetic: adopt aerosol apparatus described medicine liquid ingredient to be sprayed to the medicine for external use that obtains described treatment neck and lumbar spondylosis and arthritis ache on ointment composition.