CN103142920B - Traditional Chinese medicine composition for treating hepatitis B and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating hepatitis B and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating hepatitis B and a preparation method of the traditional Chinese medicine composition; the traditional Chinese medicine composition comprises the following components: 5-15 parts of radix bupleuri, 15-25 parts of oriental wormwood, 15-25 parts of poria cocos, 15-25 parts of umbellate pore fungus, 15-25 parts of semen coicis, 10-20 parts of schisandra chinensis, 10-20 parts of polygonum cuspidatum, 10-20 parts of the root of red-rooted salvia, 5-15 parts of semen raphani, 5-15 parts of fruit of immature citron, 5-15 parts of endothelium corneum gigeriae galli, and the like. The traditional Chinese medicine composition is low in cost of raw materials, does basically not have any toxic and side effects, has excellent effect in protecting liver, has fast curative effect, can well prompt immunity, and has the effective rate of at least 89%.
Description
Technical field
The present invention relates to field of medicaments, relate to a kind of Chinese medicine composition for the treatment of hepatitis B and preparation method thereof specifically.
Background technology
In recent years, B-type hepatitis patient increase increasingly, and especially the infection of hepatitis B virus has become the current key factor affecting social stability, the district occurred frequently of Chinese B-type hepatitis especially.The current number at Chinese Patients with Hepatitis B Virus Infection is more than 100,000,000, although the understanding of people to hepatitis B increased than in the past, but for Hepatitis B infection person, discriminate against and enter a school these people, job hunting, maximum stumbling-block is usually become when the life Important Changes such as love and marriage, how many people fall in a health check-up table is kept outside of the door, when Patients with Hepatitis B Virus Infection can break away from heavy pressure at heart, walk out the shade of discrimination, so this present situation will be changed, people must be allowed not fear hepatitis B from the heart, treatment major part now for hepatitis B is all adopt Western medicine to treat, but Western medicine is often in order to improve drug effect, the medicine that some are larger to human body side effect can be used, the weak effect for the treatment of, expensive.
Summary of the invention
The object of the invention is to overcome deficiency of the prior art and provide a kind of therapeutic effect good, cure rate is high, Chinese medicine composition of the treatment hepatitis B that toxic and side effects is little and preparation method thereof.
The object of the present invention is achieved like this:
A kind of Chinese medicine composition for the treatment of hepatitis B, be made up of the raw material of following parts by weight: Radix Bupleuri 5-15 part, Herba Artemisiae Scopariae 15-25 part, Poria 15-25 part, Polyporus 15-25 part, Semen Coicis 15-25 part, Fructus Schisandrae Chinensis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Semen Raphani 5-15 part, Fructus Aurantii Immaturus 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Rhizoma Pinelliae 5-15 part, Fructus Amomi 5-15 part, Radix Paeoniae Alba 10-20 part, Rhizoma Cyperi 5-15 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Et Rhizoma Rhei 5-15 part, Radix Morindae Officinalis 5-15 part, Flos Carthami 5-15 part, Radix Astragali 10-20 part, Radix Paeoniae Rubra 6-16 part, Herba Hedyotidis Diffusae 8-23 part, Ganoderma lucidum seu Japonicum 15-25 part.
Preferred version: be made up of the raw material of following parts by weight: Radix Bupleuri 10 parts, Herba Artemisiae Scopariae 15 parts, 20 parts, Poria, Polyporus 20 parts, Semen Coicis 20 parts, Fructus Schisandrae Chinensis 14 parts, Rhizoma Polygoni Cuspidati 12 parts, Radix Salviae Miltiorrhizae 15 parts, Semen Raphani 12 parts, Fructus Aurantii Immaturus 10 parts, Endothelium Corneum Gigeriae Galli 13 parts, Pericarpium Citri Reticulatae 10 parts, the Rhizoma Pinelliae 13 parts, Fructus Amomi 12 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Cyperi 16 parts, Radix Angelicae Sinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Et Rhizoma Rhei 11 parts, Radix Morindae Officinalis 10 parts, 10 parts, Flos Carthami, the Radix Astragali 15 parts, Radix Paeoniae Rubra 12 parts, Herba Hedyotidis Diffusae 15 parts, Ganoderma lucidum seu Japonicum 20 parts.
Treat a preparation method for the Chinese medicine composition of hepatitis B, be mixed in proportion after each raw material pulverizing powdered.
Radix Bupleuri nature and flavor in the present invention are bitter, and be slightly cold, return Liver Channel, gallbladder meridian, evacuation is brought down a fever, yang invigorating soothing liver-QI, can Promote immunity function, and effective ingredient is: Bupleurum chinense polysaccharide.Can phagocytic function be strengthened, strengthen Natural killer activity, improve the Specific antibody titre of virus, improve lymphocyte and turn core rate, improve skin delayed hypersensitivity reaction.
Herba Artemisiae Scopariae cold nature, acrid in the mouth, hardship return spleen, stomach, liver, gallbladder meridian, clearing away damp-heat, jaundice eliminating subcutaneous ulcer, for infectious jaundice hepatitis, there is significant hepatoprotective effect, for hepatitis B, icterohepatitis, there is significant curative effect, there is function of gallbladder promoting, promote bile secretion, increase the effect that in bile, cholic acid and bilirubin are discharged.
Poria sweet in the mouth, light, property are put down, GUIXIN warp, lung meridian, spleen channel, kidney channel.There is promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming.The immunologic function of enhancing body, pachyman has obvious antitumor and protects the liver dirty effect.
Polyporus sweet in the mouth, light, flat, there is promoting diuresis to eliminate damp pathogen effect.Can strengthen immunologic function, polyporusum bellatus has more significant Tumor suppression and liver-protective effect.
Semen Coicis is cool in nature, sweet in the mouth, light, has spleen invigorating eliminating dampness by diuresis effect.Can enhancing immunity and antiinflammatory, there is antineoplastic action.
Fructus Schisandrae Chinensis temperature, sour, sweet, return lung heart kidney; the five internal organs of the human body that can protect; also have abundant organic acid, vitamin, flavonoid, phytosterol and have the lignan of potent reactivation, the strong liver of QI invigorating, promote the efficiency of cells exclude refuse, supply more oxygen.Can promote the function of detoxification of liver, the liver protecting, can the liver organization of regeneration of damaged from murder by poisoning.
Rhizoma Polygoni Cuspidati nature and flavor with return through micro-hardship, be slightly cold.Return liver, gallbladder, lung meridian, heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm, there is effect of hepatoprotective, also have antibacterial disease-resistant and antineoplastic action.
Radix Salviae Miltiorrhizae is bitter, and be slightly cold, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind, has and improve liver microcirculation.
Semen Raphani property is put down, acrid in the mouth, sweet, returns lung, spleen, stomach warp, has the effect of resisting pathogenic microbes.
Fructus Aurantii Immaturus is bitter; Pungent; Cold.Return spleen; Stomach; Liver; Heart channel, can heart tonifying, calm.
Endothelium Corneum Gigeriae Galli is sweet, cold.Return spleen, stomach, small intestinal, urinary bladder channel, promoting digestion and invigorating the stomach, arresting seminal emission, the Secretion of stomach function can be promoted, there is the effect of inhibition tumor cell.
Pericarpium Citri Reticulatae is warm in nature, acrid in the mouth, bitter in the mouth, enters spleen channel, stomach warp, lung meridian, and appetizing drying dampness to eliminate phlegm of regulating the flow of vital energy controls the spleen-stomach disease, effect of function of gallbladder promoting antiinflammatory.
The Rhizoma Pinelliae is pungent, and temperature, controls gastrofrigid vomiting.
Fructus Amomi acrid in the mouth, warm in nature, return spleen channel kidney channel, stomach warp, there is removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive, can obviously suppress hematoblastic gathering.
Radix Paeoniae Alba picric acid, cool, return liver, spleen channel, nourishing blood to suppress the hyperactive liver, pain relieving in slow.
The pungent micro-hardship of Rhizoma Cyperi is sweet, flat, resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.
Radix Angelicae Sinensis is warm in nature, sweet in the mouth, pungent, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Rhizoma Atractylodis Macrocephalae bitter in the mouth; Sweet; Warm in nature, invigorating the spleen and benefiting QI; Stomach invigorating, dampness diuresis; Reduce phlegm, hidroschesis; Antiabortive, there is anticoagulation, antitumor, antibacterial, promote hemopoietic function, effect of the not only synthesis of protein.
Radix Et Rhizoma Rhei is bitter, cold, stomach warp; Large intestine channel; Liver Channel; Spleen channel, has function of gallbladder promoting and protects the liver, and promotes pancreatic secretion, the always effect of enzymatic activity, can resist pathogenic microorganism.Radix Et Rhizoma Rhei can suppress the development of hepatitis B virus, inhibited to hepatitis B antigen.
Radix Morindae Officinalis is pungent, sweet, tepor, liver; Kidney channel, can resisting fatigue, strengthens immunologic function, has the effect of antiinflammatory blood pressure lowering, effectively suppresses the development of hepatitis B virus.
Flos Carthami is warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, promoting blood circulation to restore menstrual flow, and scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache, have blood pressure lowering, resisting fatigue, antiinflammatory, Flos Carthami has induction role and the growth-promoting functions of endogenous interferon, can produce interferon.
Radix Astragali sweet in the mouth, slightly warm in nature, returns liver, spleen, lung, kidney channel.Inrigorating qi and promoting blood circulation, blood stasis dispelling.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.There is cardiotonic, but microcirculation disturbance recovers normal.
Radix Paeoniae Rubra is bitter, is slightly cold.Return Liver Channel, clearing away heat and cooling blood; Blood circulation promoting and blood stasis dispelling, but microcirculation recovers normal.
Herba Hedyotidis Diffusae hardship is sweet, cold.Nontoxic, clearing away heat-damp and promoting diuresis, removing toxic substances, controls dyspnea and cough due to lung-heat, etc.There is antitumor action, also have effect of anti-inflammation.
Ganoderma lucidum seu Japonicum feeble QI is fragrant, bitter and puckery flavor, GUIXIN, liver, spleen, lung, the kidney Five Classics.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, the animal pharmacological experiments such as malignant tumor, Ganoderma has inhibitory action to nervous system, blood circulation has blood pressure lowering and strengthens the effect of cardiac contractile force, phlegm-dispelling functions is had to respiratory system, in addition, also have liver detoxification, improve immunologic function, effect such as antibacterial grade. also have effect of neurasthenia.
Cost of material of the present invention is low, does not substantially have toxic and side effects, and hepatoprotective is effective, and recover rapidly, good Promote immunity function, effective percentage is at least 89%.
By adopting prescription of the present invention in recent years, achieved good curative effect:
1, clinical:
Select 100 routine hepatitis B patients to treat, men and women, between 20-60, wherein separates by the age, man 60, female 40, have the hepatitis B medical history of different time, by doing a detailed registration and record to the current state of an illness of each patient, so that in the later stage as the foundation compared.
Adopt potion every day, with being decocted in water for oral dose, sooner or later each once oral.It within one week, is a course for the treatment of.Four-six courses for the treatment of of general needs.
The standard of efficacy determination:
1) cure: symptom all disappears, liver function recovery.
1) effective: symptom disappears substantially, liver function is recovered substantially.
2) effective: transference cure or substantially disappear, not having obvious tenderness feel, there is recovery sign in liver function.
3) invalid: without any improvement.
2, result:
By after taking medicine with take medicine before symptom compare and statistics draws:
After four courses for the treatment of: in 100 routine patients, result is healing 18 example, and account for 18%, effective 30, account for 30%, effective 41%, account for 41%, invalid 11, account for 11%, total effective rate is 89%.
After five courses for the treatment of: in 100 routine patients, result is healing 25 example, and account for 25%, effective 32, account for 32%, effective 35%, account for 35%, invalid 8, account for 8%, total effective rate is 92%.
After six courses for the treatment of: in 100 routine patients, result is healing 30 example, and account for 30%, effective 36, account for 36%, effective 29%, account for 29%, invalid 5, account for 5%, total effective rate is 92%.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition for the treatment of hepatitis B, be made up of the raw material of following parts by weight: Radix Bupleuri 5 parts, Herba Artemisiae Scopariae 15 parts, 15 parts, Poria, Polyporus 15 parts, Semen Coicis 15 parts, Fructus Schisandrae Chinensis 10 parts, Rhizoma Polygoni Cuspidati 10 parts, Radix Salviae Miltiorrhizae 10 parts, Semen Raphani 5 parts, Fructus Aurantii Immaturus 5 parts, Endothelium Corneum Gigeriae Galli 5 parts, Pericarpium Citri Reticulatae 5 parts, the Rhizoma Pinelliae 5 parts, Fructus Amomi 5 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Cyperi 5 parts, Radix Angelicae Sinensis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Et Rhizoma Rhei 5 parts, Radix Morindae Officinalis 5 parts, 5 parts, Flos Carthami, the Radix Astragali 10 parts, Radix Paeoniae Rubra 6 parts, Herba Hedyotidis Diffusae 8 parts, Ganoderma lucidum seu Japonicum 15 parts, mix after each raw material pulverizing powdered, 20-30 minute is boiled by slow fire or moderate heat, .
Embodiment 2: boiling method is the same, concrete formula is as follows:
Treat a Chinese medicine composition for hepatitis B, be made up of the raw material of following parts by weight: Radix Bupleuri 15 parts, Herba Artemisiae Scopariae 25 parts, 25 parts, Poria, Polyporus 25 parts, Semen Coicis 25 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Salviae Miltiorrhizae 20 parts, Semen Raphani 15 parts, Fructus Aurantii Immaturus 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Pericarpium Citri Reticulatae 15 parts, the Rhizoma Pinelliae 15 parts, Fructus Amomi 15 parts, the Radix Paeoniae Alba 20 parts, Rhizoma Cyperi 15 parts, Radix Angelicae Sinensis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Et Rhizoma Rhei 15 parts, Radix Morindae Officinalis 15 parts, 15 parts, Flos Carthami, the Radix Astragali 20 parts, Radix Paeoniae Rubra 16 parts, Herba Hedyotidis Diffusae 23 parts, Ganoderma lucidum seu Japonicum 25 parts.
Embodiment 3: boiling method is the same, concrete formula is as follows:
Be made up of the raw material of following parts by weight: Radix Bupleuri 5 parts, Herba Artemisiae Scopariae 25 parts, 25 parts, Poria, Polyporus 25 parts, Semen Coicis 25 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Salviae Miltiorrhizae 20 parts, Semen Raphani 15 parts, Fructus Aurantii Immaturus 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Pericarpium Citri Reticulatae 15 parts, the Rhizoma Pinelliae 15 parts, Fructus Amomi 15 parts, the Radix Paeoniae Alba 20 parts, Rhizoma Cyperi 15 parts, Radix Angelicae Sinensis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Et Rhizoma Rhei 15 parts, Radix Morindae Officinalis 5-15 part, Flos Carthami 5-15 part, the Radix Astragali 20 parts, Radix Paeoniae Rubra 6 parts, Herba Hedyotidis Diffusae 8 parts, Ganoderma lucidum seu Japonicum 15 parts.
Embodiment 4: boiling method is the same, concrete formula is as follows:
Be made up of the raw material of following parts by weight: Radix Bupleuri 15 parts, Herba Artemisiae Scopariae 25 parts, 25 parts, Poria, Polyporus 25 parts, Semen Coicis 25 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Salviae Miltiorrhizae 20 parts, Semen Raphani 15 parts, Fructus Aurantii Immaturus 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Pericarpium Citri Reticulatae 15 parts, the Rhizoma Pinelliae 5 parts, Fructus Amomi 15 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Cyperi 15 parts, Radix Angelicae Sinensis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Et Rhizoma Rhei 5 parts, Radix Morindae Officinalis 5 parts, 15 parts, Flos Carthami, the Radix Astragali 20 parts, Radix Paeoniae Rubra 16 parts, Herba Hedyotidis Diffusae 23 parts, Ganoderma lucidum seu Japonicum 25 parts.
Embodiment 5: a kind of Chinese medicine composition for the treatment of hepatitis B, is characterized in that: be made up of the raw material of following parts by weight: Radix Bupleuri 10 parts, Herba Artemisiae Scopariae 15 parts, 20 parts, Poria, Polyporus 20 parts, Semen Coicis 20 parts, Fructus Schisandrae Chinensis 14 parts, Rhizoma Polygoni Cuspidati 12 parts, Radix Salviae Miltiorrhizae 15 parts, Semen Raphani 12 parts, Fructus Aurantii Immaturus 10 parts, Endothelium Corneum Gigeriae Galli 13 parts, Pericarpium Citri Reticulatae 10 parts, the Rhizoma Pinelliae 13 parts, Fructus Amomi 12 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Cyperi 16 parts, Radix Angelicae Sinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Et Rhizoma Rhei 11 parts, Radix Morindae Officinalis 10 parts, 10 parts, Flos Carthami, the Radix Astragali 15 parts, Radix Paeoniae Rubra 12 parts, Herba Hedyotidis Diffusae 15 parts, Ganoderma lucidum seu Japonicum 20 parts.This formula is optimization formula.
Concrete case:
Case 1: poplar, man 25 years old, pipe city, Zhengzhou City Henan Province, on October 5th, 2009, so-and-so examination in hospital 1.4.5 was positive in Zhengzhou City, made a definite diagnosis hepatitis B.December starts to take medicine on the 10th, and after taking five courses for the treatment of, with on January 25th, 2010 in Zhengzhou Clinical Laboratory center monitors, recovery from illness, check result is < 1.0 × 10-
3, negative reference value is < 1.0 × 10-
3.
Case 2: grandson, man 40 years old, pipe city, Zhengzhou City Henan Province, on March 5th, 2010, so-and-so examination in hospital 1.4.5 was positive in Zhengzhou City, made a definite diagnosis hepatitis B.April 10 started to take medicine, and after taking 6 courses for the treatment of, with May 25 in Zhengzhou Clinical Laboratory center monitors, recovery from illness, check result is < 4.22 × 10-
3, negative reference value is < 1.0 × 10-
3.
Case 3: Zheng, man 30 years old, pipe city, Zhengzhou City Henan Province, in Zhengzhou City, so-and-so examination in hospital 1.4.5 was positive on 7th for JIUYUE in 2010, made a definite diagnosis hepatitis B.JIUYUE starts to take medicine on the 20th, and after taking 6 courses for the treatment of, with on November 7th, 2010 in Zhengzhou Clinical Laboratory center monitors, recovery from illness, check result is < 3.0 × 10
6, negative reference value is < 1.0 × 10-
3.
Claims (2)
1. treat the Chinese medicine composition of hepatitis B for one kind, it is characterized in that: be made up of the raw material of following parts by weight: Radix Bupleuri 5-15 part, Herba Artemisiae Scopariae 15-25 part, Poria 15-25 part, Polyporus 15-25 part, Semen Coicis 15-25 part, Fructus Schisandrae Chinensis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Semen Raphani 5-15 part, Fructus Aurantii Immaturus 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Rhizoma Pinelliae 5-15 part, Fructus Amomi 5-15 part, Radix Paeoniae Alba 10-20 part, Rhizoma Cyperi 5-15 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Et Rhizoma Rhei 5-15 part, Radix Morindae Officinalis 5-15 part, Flos Carthami 5-15 part, Radix Astragali 10-20 part, Radix Paeoniae Rubra 6-16 part, Herba Hedyotidis Diffusae 8-23 part, Ganoderma lucidum seu Japonicum 15-25 part.
2. a preparation method for Chinese medicine composition according to claim 1, is characterized in that: mix after each raw material pulverizing powdered.
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| CN103330034A (en) * | 2013-07-16 | 2013-10-02 | 太仓市伟基生物科技有限公司 | Liver soothing and toxin removal tea |
| CN103751658B (en) * | 2014-02-22 | 2015-11-11 | 储可英 | A kind ofly treat medicine of the hepatitis B that damp-heat accumulation causes and preparation method thereof |
| CN104906452A (en) * | 2015-06-12 | 2015-09-16 | 汤华淑 | Traditional Chinese medicine composition for treating hepatitis B |
| CN106110274B (en) * | 2016-08-18 | 2019-08-30 | 陈定潜 | It is a kind of for treating the Chinese medicine composition and preparation method thereof of chronic viral hepatitis or hepatic failure |
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