CN103142816B - A kind of Chinese medicine wine for external use and preparation method thereof - Google Patents
A kind of Chinese medicine wine for external use and preparation method thereof Download PDFInfo
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Abstract
The invention provides a kind of Chinese medicine wine for external use and preparation method thereof, described Chinese medicine wine for external use is made up of following raw material: crude drug agent A: Radix aristolochiae tubiflorae 15% ~ 20%, Rhizoma Paridis 10% ~ 15%, serpent are raw 8% ~ 12%, Herba Botrychii 8% ~ 12%, JIUYUE spend 5% ~ 10%, Herba Solidaginis 4% ~ 6%, Herba Veronicastri 8% ~ 12%, flipper 4% ~ 6%, Herba Caryopteridis Terniflorae 8% ~ 12%, black ox egg 5% ~ 8%, Scolopendra Artemisia 5% ~ 9%; Batching B, medical alcohol, purity is 55 degree ~ 70 degree; Wherein, crude drug agent and alcohol content ratio are 3:7.Manufacture method comprises step: carry out former medicine selection according to standard recipe, be crushed to 40-60 order respectively, with wine or ethanol, airtight standing, every day stirs once, within 7th, stirs latter airtight 30 days totally, extracts supernatant, add equivalent wine to soak again and squeeze the juice for 72 hours, mixing supernatant, obtain through sedimentation and filtration.Formula of the present invention is simple, and make simple and direct, with low cost, easy to use, external has no side effect, and the cycle of curing is short.
Description
Technical field
The invention belongs to Chinese medicine and Chinese drug preparation field, relate to a kind of external application Chinese medicine and preparation method thereof, especially relate to a kind of Chinese medicine wine for external use and preparation method thereof.
Background technology
Poisonous snake poison beast, insect-bite, various skin infection and bromhidrosis belong to multiple, common venereal diseases disease.Particularly venom, if treatment is not in time, can crisis life.Pathogenesis is that venom toxin enters human body and produces infringement to body cell, blood, makes it generation and has an intense pain, swelling, hemorrhage.Toxin also enters blood by microcirculation.Invade heart, cause myocardial necrosis hemorrhage and dead.Bromhidrosis is a kind of abnormal oozy antiperspirant sexual secretion by axillary gland, because of its cacosmia, has a strong impact on physiology and healthy at heart.The skin infection that a variety of causes causes is the special anaphylaxis of its infector tool, zest.Skin pruritus, erythra, painful abdominal mass joint can be caused, fester.All diseases above, there is no specific medicament in the market can be quick, easy, efficient medicine.
The present invention aims to provide a kind of employing Chinese herbal medicine or its preparation, and preparation one adopts topical route completely, fast, safety, effective medicated wine, its curative effect can be better than existing market similar drug, be used for treating poisonous snake, malicious Veterinary, insect-bite, and bromhidrosis and skin infection etc.
Summary of the invention
Problem to be solved by this invention is to provide a kind of Chinese medicine wine for external use, and described Chinese medicine wine for external use is made up of following raw material:
Crude drug agent A: Radix aristolochiae tubiflorae 15% ~ 20%, Rhizoma Paridis 10% ~ 15%, Radix Aristolochiae 8% ~ 12%, Herba Botrychii 8% ~ 12%, JIUYUE spend 5% ~ 10%, Herba Solidaginis 4% ~ 6%, Herba Veronicastri 8% ~ 12%, flipper 4% ~ 6%, Herba Caryopteridis Terniflorae 8% ~ 12%, limacia sagittata 5% ~ 8%, Scolopendra Artemisia 5% ~ 9%;
Batching B, medical alcohol, purity is 55 degree ~ 70 degree;
Wherein, crude drug agent and alcohol content ratio are 3:7.
Preferably, described Chinese medicine wine for external use is made up of following raw material:
Crude drug agent A: Radix aristolochiae tubiflorae 16.7%, Rhizoma Paridis 13.34%, Radix Aristolochiae 10%, Herba Botrychii 10%, JIUYUE spend 6.67%, Herba Solidaginis 5%, Herba Veronicastri 10%, flipper 5%, Herba Caryopteridis Terniflorae 10%, limacia sagittata 6.65%, Scolopendra Artemisia 6.64%;
Batching B, medical alcohol, purity is 55 ~ 70 degree;
Wherein, crude drug agent and the ethanol adding proportion medicament A that makes a living accounts for gross mass 30%.
Further, in described Chinese medicine wine for external use, in crude drug agent A, all material takes standard volume by following:
Every 100ml medical alcohol is altogether containing crude drug 30 grams; Described Chinese medicine wine for external use ethanol purity used should reach between 55 degree to 70 degree.
Introduce the manufacture method of Chinese medicine wine for external use of the present invention below, its technological process is as follows:
---standard recipe---is crushed to 40-60 order respectively---and adds raw wine or ethanol in former medicine selection, airtight standing---every day stirs once, within 7, stir latter airtight 30 days---extract supernatant, add equivalent wine and soak---mixing supernatant---precipitation---filtration---subpackage------packaging---storage of labelling of squeezing the juice for 72 hours again.
A manufacture method for Chinese medicine wine for external use, comprises the following steps:
(1) former medicine selection, takes crude drug agent A: Radix aristolochiae tubiflorae, Rhizoma Paridis, Radix Aristolochiae, Herba Botrychii, JIUYUE flower, Herba Solidaginis, Herba Veronicastri, flipper, Herba Caryopteridis Terniflorae, limacia sagittata, Scolopendra Artemisia in proportion;
(2) 40-60 order is pulverized in above-mentioned crude drug agent respectively, put into sealable pharmaceutical tank, add ethanol, addition is made a living 2 ~ 3 times of medicament; Sealing and standing is soaked;
(3) above-mentioned confection A is stirred once every day, after within 7, stirring, soak 30 under sealing room temperature;
(4) pharmacy jar of sealing immersion after 30 days is opened, extract supernatant; Residue confection is added equivalent ethanol and carries out secondary immersion, soak time is 72 hours;
(5) squeezed the juice by the confection B soaked through secondary, the supernatant extracted with step (4) after squeezing the juice mixes, and after fully precipitating, filters;
(6) Chinese medicinal liquor after filtration is carried out sealing subpackage until become namely to make described Chinese medicine wine for external use, the described exterior-applied medical wine alcohol content made is not less than 55 degree, not higher than 65 degree.
In described step (3), mixing time is 5 ~ 10 minutes, is evenly as the criterion all to stir.
Further, medicated wine of the present invention is available following manufacture method preparation also, comprise the following steps: take each crude drug composition in crude drug agent A by standard, be placed in one or more terrine, add triplication more than 55 degree Chinese liquor respectively, seal 60, after the whole stripping of medicine juice, extract supernatant, staticly settle, filter; Detecting alcohol content is more than 55 degree; Appropriate medical alcohol is added time not enough; Label after subpackage, packing and storing.
For the preparation of low dose, according to dosage can make up a prescription, medical material is directly put into terrine or vial, add 60 degree of soaking in Chinese liquor after 30 days, can use by taking liquid.
External application Chinese medicine wine liquid of the present invention is deep yellow reddish, and without precipitation, bitter in the mouth is pungent, micro-fiber crops.The principle of the invention: the external of described medicated wine system, need have the osmosis of some strength.65 degree be clinical middle through test institute obtain data.Have quick permeation, zest is relatively a little little.
Described Chinese medicine wine for external use makes points for attention:
The medicated wine system multiple medicines taste formula of the present invention, need be mixed with, inapplicable active ingredient extraction method.
In the present invention, part Chinese medicine (as Radix Tinosporae) heat or high temperature can lose drug effect, are not suitable for heat treating process.
Chinese medicine preparation of the present invention, should adhere to standard raw materials medicine, standard dose, proof-spirit content.(alcohol content is not less than 55 degree)
Medicament stock selected by the present invention:
1. Radix aristolochiae tubiflorae, nature and flavor toil is trembled with fear, and returns Liver Channel.The pain relieving of tool promoting flow of QI and blood, removing toxic substances and promoting subsidence of swelling.Stomach stomachache can be treated, venom, bee sting, innominate toxic swelling, traumatic injury.
2. Rhizoma Paridis, namely Rhizoma Paridis, hardship, be slightly cold, and returns Liver Channel.Slightly poisonous, there is heat-clearing and toxic substances removing, detumescence, arresting convulsion.For carbuncle sore tumefacting virus, pharyngeal swelling sore throat, snake bite and insect sting, traumatic pain; Record in " the southern regions of the Yunnan Province book on Chinese herbal medicine " and cure mainly all innominate toxic swellings etc.
3. Radix Aristolochiae, another name Fructus Aristolochiae root, toil is trembled with fear, mild toxicity.Return lung, stomach, Liver Channel.There is circulation of qi promoting removing toxic substances, detumescence.Cure mainly abdominal distention, snake bite and insect sting, carbuncle furuncle, tinea alba, eczema, skin pruritus.
4. keep away Serpentis raw, another name Herba Botrychii, Herba Botrychii.Sweetness and bitterness is slightly cold.Heat clearing away, suppressing the hyperactive liver, cough-relieving, removing toxic substances, effect of improving eyesight.Cure mainly that infantile hyperpyrexia is frightened jerks, cough due to lung-heat, hemoptysis, scrofula, pertussis, sore swollen toxin; Effect that it has heat-clearing and toxic substances removing is also recorded in " Yunnan Chinese herbal medicine ".Cure mainly poisonous snake, lyssodexis.
5. JIUYUE flower, has another name called Gentiana rhodantha Franch., bitter cold, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure mainly lung-heat cough with asthma, infantile convulsion, conjunctival congestion and swelling pain, jaundice, burn and scald, venom.。
6. Herba Veronicastri, another name Herba veronicastri villosuli.Bitter in the mouth is cold in nature, detumescence of relieving oedema or abdominal distension through diuresis or purgation, blood circulation promoting and blood stasis dispelling effect.Cirrhotic ascites can be treated, innominate toxic swelling, venom etc.
7. flipper, has another name called Caulis et folium cryptotaeniae japonicae, arduous flat.Dispelling wind stopping cough, eliminating damp, detoxifying, silt releasing and analgesia.Cure mainly cold cough, lung abscess, drench pain, hernia, skin pruritus treating swelling and pain by traumatic injury, snake bite and insect sting etc.
8. Herba Caryopteridis Terniflorae, acrid in the mouth, micro-hardship, property is put down.Dispelling wind to relieve the exterior syndrome, lung qi dispersing cough-relieving.Cure mainly flu, cough, burn due to hot liquid or fire etc.，
9. limacia sagittata, Herba Elephantopi scaberis, nature and flavor bitter cold.Energy heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling, cures mainly acute pharyngitis, tonsillitis, acute gastroenteritis, stomachache, bacillary dysentery.Carbuncle furunculosis, venom.
10. Scolopendra Artemisia, another name Achillea millefolium L., Herba Achilleae; Sweet in the mouth, hardship, pungent, slightly poisonous.Dispel the wind, invigorate blood circulation, pain relieving, removing toxic substances.Cure mainly rheumatic arthralgia, traumatic injury, dysmenorrhea due to blood stasis, carbuncle sore tumefacting virus, bleeding hemorrhoids.
11. Herba Solidaginiss, the property of medicine is worked hard cool.Wind and heat dispersing, subduing swelling and detoxicating.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, jaundice, pyretic stranguria, carbuncle furuncle, venom, traumatic injury.
Beneficial effect of the present invention is:
1. there is Detoxication; After medicated wine preparation, generate complicated chemical analysis each other by the function of its each medical material own and through compatibility, to Serpentis, Veterinary, honeybee, insect bite wound in clinical, all can obtain effect.
2. there is blood coagulation fast and antihemolysis.Sting rear and post-traumatic hemorrhage to all kinds of snakebite, Veterinary in clinical, have anastalsis.Particularly there is hemolytic factor in snake venom, cell tissue haemolysis can be made, after using this product, have good effect.
3. have good, the antiinflammatory of wide spectrum, anti-infectious function, square Chinese medicine majority dispel the wind, heat clearing away, removing toxic substances, detumescence effect.Clinical practice is extensive, instant effect.Infect certain plants anaphylaxis, mosquito bite, it is namely good to make namely to put on the skin.To infecting the erythra, the furuncle that cause, outer obliterating is smeared.Immediately come into force.
Detailed description of the invention
embodiment 1
Take in following ratio:
In crude drug agent A, all material takes standard volume by following:
The above-mentioned medical material taken directly is put into terrine or vial, adds 60 degree of soaking in Chinese liquor after 30 days, can use by taking liquid.Examination criteria is that every 100ml medical alcohol is altogether containing crude drug 30 grams; Described Chinese medicine wine for external use ethanol purity used should reach between 55 degree to 70 degree.
Embodiment 2
Take in following ratio:
In crude drug agent A, all material takes standard volume by following:
Take each crude drug composition in crude drug agent A by standard, be placed in one or more terrine, add triplication more than 55 degree Chinese liquor respectively, seal 60, after the whole stripping of medicine juice, extract supernatant, staticly settle, filter; Detecting alcohol content is more than 55 degree; Appropriate medical alcohol is added time not enough; Label after subpackage, packing and storing.
embodiment 3
Take in following ratio, prepare each component of crude drug agent A:
Crude drug agent A: Radix aristolochiae tubiflorae 16.7%, Rhizoma Paridis 13.34%, Radix Aristolochiae 10%, Herba Botrychii 10%, JIUYUE spend 6.67%, Herba Solidaginis 5%, Herba Veronicastri 10%, flipper 5%, Herba Caryopteridis Terniflorae 10%, limacia sagittata 6.65%, Scolopendra Artemisia 6.64%;
Batching B, medical alcohol, purity is 55 ~ 70 degree; Wherein, crude drug agent and the ethanol adding proportion medicament A that makes a living accounts for gross mass 30%.
Take crude drug agent A according to the above ratio: Radix aristolochiae tubiflorae, Rhizoma Paridis, Radix Aristolochiae, Herba Botrychii, JIUYUE flower, Herba Solidaginis, Herba Veronicastri, flipper, Herba Caryopteridis Terniflorae, limacia sagittata, Scolopendra Artemisia; 60 orders are pulverized in above-mentioned crude drug agent respectively, puts into sealable pharmaceutical tank, add ethanol, addition is made a living 3 times of medicament; Sealing and standing is soaked; Above-mentioned confection A is stirred once every day, each stirring 10 minutes, after within 7, stirring, soak 30 under sealing room temperature; The pharmacy jar of sealing immersion after 30 days is opened, extracts supernatant; Residue confection is added equivalent ethanol and carries out secondary immersion, soak time is 72 hours; Squeezed the juice by the confection B soaked through secondary, the supernatant extracted with step (4) after squeezing the juice mixes, and after fully precipitating, filters; Chinese medicinal liquor after filtering is carried out sealing subpackage until become namely to make described Chinese medicine wine for external use, and the described exterior-applied medical wine alcohol content made is 65 degree.The external of described medicated wine system, need have the osmosis of some strength.65 degree be clinical middle through test institute obtain data.Have quick permeation, zest is relatively a little little.
Embodiment 4
Take in following ratio, prepare each component of crude drug agent A:
Crude drug agent A: Radix aristolochiae tubiflorae 18%, Rhizoma Paridis 12%, Radix Aristolochiae 9%, Herba Botrychii 10%, JIUYUE spend 8%, Herba Solidaginis 6%, Herba Veronicastri 10%, flipper 4.5%, Herba Caryopteridis Terniflorae 10%, limacia sagittata 6%, Scolopendra Artemisia 6.5%;
Batching B, medical alcohol, purity is 55 degree ~ 70 degree;
Wherein, crude drug agent and alcohol content ratio are 3:7.Former medicine selection, takes crude drug agent A: Radix aristolochiae tubiflorae, Rhizoma Paridis, Radix Aristolochiae, Herba Botrychii, JIUYUE flower, Herba Solidaginis, Herba Veronicastri, flipper, Herba Caryopteridis Terniflorae, limacia sagittata, Scolopendra Artemisia in proportion; 40-60 order is pulverized in above-mentioned crude drug agent respectively, puts into sealable pharmaceutical tank, add ethanol, addition is made a living 2 ~ 3 times of medicament; Sealing and standing is soaked; Above-mentioned confection A is stirred once every day, stirs 5 ~ 10 minutes at every turn, be as the criterion fully to stir to turn over, after within 7, stirring, soak 30 under sealing room temperature; The pharmacy jar of sealing immersion after 30 days is opened, extracts supernatant; Residue confection is added equivalent ethanol and carries out secondary immersion, soak time is 72 hours; Squeezed the juice by the confection B soaked through secondary, the supernatant extracted with step (4) after squeezing the juice mixes, and after fully precipitating, filters; Chinese medicinal liquor after filtering is carried out sealing subpackage until become namely to make described Chinese medicine wine for external use, and the described exterior-applied medical wine alcohol content made is 55 degree.
Embodiment 5
Take in following ratio, prepare each component of crude drug agent A:
Crude drug agent A: Radix aristolochiae tubiflorae 16%, Rhizoma Paridis 14%, Radix Aristolochiae 11%, Herba Botrychii 11%, JIUYUE spend 8.5%, Herba Solidaginis 5.5%, Herba Veronicastri 8.9%, flipper 5.5%, Herba Caryopteridis Terniflorae 8%, limacia sagittata 6%, Scolopendra Artemisia 5.6%;
Batching B, medical alcohol, purity is 55 degree ~ 70 degree;
Wherein, crude drug agent and alcohol content ratio are 3:7.
Former medicine selection, takes crude drug agent A: Radix aristolochiae tubiflorae, Rhizoma Paridis, Radix Aristolochiae, Herba Botrychii, JIUYUE flower, Herba Solidaginis, Herba Veronicastri, flipper, Herba Caryopteridis Terniflorae, limacia sagittata, Scolopendra Artemisia in proportion; 40-60 order is pulverized in above-mentioned crude drug agent respectively, puts into sealable pharmaceutical tank, add ethanol, addition is made a living 2 ~ 3 times of medicament; Sealing and standing is soaked; Above-mentioned confection A is stirred once every day, stirs 10 minutes at every turn, after within 7, stirring, sealing immersion 30 days; The pharmacy jar of sealing immersion after 30 days is opened, extracts supernatant; Residue confection is added equivalent ethanol and carries out secondary immersion, soak time is 72 hours; Squeezed the juice by the confection B soaked through secondary, the supernatant extracted with step (4) after squeezing the juice mixes, and after fully precipitating, filters; Chinese medicinal liquor after filtering is carried out sealing subpackage until become namely to make described Chinese medicine wine for external use, and the described exterior-applied medical wine alcohol content made is 60 degree.
This medicated wine beneficial effect implementation method
The strain external that the present invention is prepared
One: poisonous snake, malicious Veterinary bite: soak this wine with binder or sterilization cloth and be tightly wound around wrapping from swelling place front ten centimeters of places to wound direction.Height moisturizing, fades gradually tight, observes at any time, to swelling, goes out blood stasis block and disappears.
Two: process wound: sit gauze piece with this wine, Topical dressings process.
Three: other infects: absorbent cotton leaching medicine is coated with to be put on the skin.
Claims (5)
1. a Chinese medicine wine for external use, is characterized in that: described Chinese medicine wine for external use is made up of following raw material:
Crude drug agent A: Radix aristolochiae tubiflorae 15% ~ 20%, Rhizoma Paridis 10% ~ 15%, Radix Aristolochiae 8% ~ 12%, Herba Botrychii 8% ~ 12%, JIUYUE spend 5% ~ 10%, Herba Solidaginis 4% ~ 6%, Herba Veronicastri 8% ~ 12%, flipper 4% ~ 6%, Herba Caryopteridis Terniflorae 8% ~ 12%, limacia sagittata 5% ~ 8%, Scolopendra Artemisia 5% ~ 9%;
Batching B, medical alcohol, purity is 55 degree ~ 70 degree;
Wherein, crude drug agent and alcohol content ratio are 3:7.
2. Chinese medicine wine for external use according to claim 1, is characterized in that: described Chinese medicine wine for external use is made up of following raw material:
Crude drug agent A: Radix aristolochiae tubiflorae 16.7%, Rhizoma Paridis 13.34%, Radix Aristolochiae 10%, Herba Botrychii 10%, JIUYUE spend 6.67%, Herba Solidaginis 5%, Herba Veronicastri 10%, flipper 5%, Herba Caryopteridis Terniflorae 10%, limacia sagittata 6.65%, Scolopendra Artemisia 6.64%;
Batching B, medical alcohol, purity is 55 ~ 70 degree;
Wherein, crude drug agent and the ethanol adding proportion medicament A that makes a living accounts for gross mass 30%.
3. the manufacture method of a kind of Chinese medicine wine for external use according to claim 1 and 2, is characterized in that, described manufacture method comprises the following steps:
(1) former medicine selection, takes crude drug agent A: Radix aristolochiae tubiflorae, Rhizoma Paridis, Radix Aristolochiae, Herba Botrychii, JIUYUE flower, Herba Solidaginis, Herba Veronicastri, flipper, Herba Caryopteridis Terniflorae, limacia sagittata, Scolopendra Artemisia in proportion;
(2) 40-60 order is pulverized in above-mentioned crude drug agent respectively, put into sealable pharmaceutical tank, add medical alcohol, addition is made a living 2 ~ 3 times of medicament; Sealing and standing is soaked;
(3) fully stirred once every day by above-mentioned confection A, after within 7, stirring, sealing, soaks 30 under room temperature;
(4) pharmacy jar of sealing immersion after 30 days is opened, extract supernatant; Residue confection is added equivalent medical alcohol and carries out secondary immersion, soak time is 72 hours;
(5) squeezed the juice by the confection B soaked through secondary, the supernatant extracted with step (4) after squeezing the juice mixes, and after fully precipitating, filters;
(6) Chinese medicinal liquor after filtration is carried out sealing subpackage and namely make described Chinese medicine wine for external use, the described exterior-applied medical wine alcohol content made is not less than 55 degree, not higher than 65 degree.
4. the manufacture method of a Chinese medicine wine for external use, it is characterized in that, described manufacture method comprises the following steps: take each crude drug composition in crude drug agent A by the standard of claim 1 or 2, be placed in one or more terrine, add triplication more than 55 degree Chinese liquor respectively, seal 60, after the whole stripping of medicine juice, extract supernatant, staticly settle, filter; Detecting alcohol content is more than 55 degree; Appropriate medical alcohol is added time not enough; Label after subpackage, packing and storing.
5. the manufacture method of a kind of Chinese medicine wine for external use according to claim 3, is characterized in that, in described step (3), mixing time is 5 ~ 10 minutes, is evenly as the criterion all to stir.
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| CN1903256A (en) * | 2005-07-25 | 2007-01-31 | 潘兰花 | Medicated wine for treating bites by posionous snake |
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| CN1903256A (en) * | 2005-07-25 | 2007-01-31 | 潘兰花 | Medicated wine for treating bites by posionous snake |
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