CN103142210A - Peripheral refraction measuring method based on OCT technology - Google Patents
Peripheral refraction measuring method based on OCT technology Download PDFInfo
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- CN103142210A CN103142210A CN2013100599437A CN201310059943A CN103142210A CN 103142210 A CN103142210 A CN 103142210A CN 2013100599437 A CN2013100599437 A CN 2013100599437A CN 201310059943 A CN201310059943 A CN 201310059943A CN 103142210 A CN103142210 A CN 103142210A
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Abstract
The invention relates to a peripheral refraction measuring method based on OCT (optical coherence tomography) technology. The peripheral refraction measuring method based on OCT technology comprises the following steps: an OCT system is used for one-time imaging to refraction medium and retina inside an bulbus oculi so as to obtain OCT image; image processing software is used for analyzing OCT image so as to obtain forms and range information of all refraction interfaces and retina; an optical path tracing method is used for obtaining center refractive power in the visual axis direction and peripheral refraction force forming any angle with a visual axis; and the difference value of the peripheral refraction force at any angle and the center refraction force is calculated so as to obtain the peripheral refraction force value. According to the method, all that is needed is to acquire full-eye OCT image in one step through a full-eye imaging high resolution OCT system, ongoing implementation can be processed through software, and the method is quick and accurate in measuring.
Description
Technical field
The present invention relates to medical science and optoelectronic areas, be specifically related to a kind of peripheral refraction measuring method based on the OCT technology.
Background technology
The concept of peripheral refraction is equaled to propose in 1931 by Ferree at first, the refractive power in the peripheral visual field that peripheral refraction power refers to form an angle with the optical axis, the retrobulbar focus state of light incident that namely forms an angle with the optical axis.Focus and amphiblestroid relative position according to incident ray also can be divided into the states such as myopia, relative hypermetropia relatively.Central authorities and peripheral refraction power are the main indexs of appraiser's refraction of eye state intactly.More past periphery, the numerical value of peripheral refraction power and the difference of central refractive power are larger, and astigmatism and the high-order aberrations such as spherical aberration, coma can occur.
Peripheral refraction power is having great importance in clinical ophthalmology and scientific research, has become myopia studies and the common test item of pediatric ophthalmology at present.(1) peripheral refraction power is the key factor that affects mypia progression.Study verified: myopia peripheral refraction state is different with emmetropia, shows as peripheral relative hypermetropia, and the stimulation of this periphery out of focus can cause axial growth, thereby causes mypia progression; Although make light focusing that c gl makes boresight direction at macula lutea, because periphery still is in the relative hypermetropia state, still can cause myopia development.(2) peripheral refraction is the key factor of regulation and control human eye emmetropization process.Zoopery shows, the size of peripheral refraction power and character play an important role in the growth course of regulation and control eyeball.
The method of measuring at present peripheral refraction power is to utilize the infrared eye refractometer of opening the visual field, and the rotation by a cover fixation object guiding eye position or a position makes the optical axis of eyeball and apparatus measures light form an angle, thereby measures the peripheral refraction number of degrees of this angle.There is apparent in view defective in these methods: when rotate (1) eye position, due to utmost point section eyeball shape after extraocular muscles contraction meeting impact; (2) by existing measuring method, subject's head is fixed on the instrument carriage, and the below is placed on the jaw holder, forehead is close to E Tuo, watch sighting target attentively and be fixed on instrument the place ahead, but because there are individual variation in forehead, eyeball with respect to the position of forehead, there is certain error in taking measurement of an angle of peripheral refraction.(3) Measuring Time is long, and by existing routine, the peripheral refraction power of measuring 7 angles needs 40 minutes at least, if count the time of mydriasis in need 1.5 hours; And the measured mostly is the child of more than 10 years old, and the reduction of fitness directly affects measurement result.(4) due to the reason of (2), can only sighting target be set in some fixing angles, therefore, can't measure peripheral refraction at any angle.(5) watch the sighting target operated by rotary motion attentively before eyes, can cause that experimenter's nearly perception is regulated, affect result.
Summary of the invention
According to the deficiencies in the prior art, the invention provides a kind of peripheral refraction measuring method based on the OCT technology, the method is measured fast accurate.
According to the deficiencies in the prior art, technical scheme provided by the invention is: a kind of peripheral refraction measuring method based on the OCT technology, and described method comprises:
Utilize the OCT system to carry out one-time imaging to intraocular refracting media and retina, obtain the OCT image;
Utilize image processing software to analyze described OCT image, to obtain each refractive interface and amphiblestroid form and range information;
Utilize the optical path-tracing method, obtain the central refraction power of boresight direction and the peripheral refraction power that becomes unspecified angle with the described optical axis;
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central refraction power, obtain thus the peripheral refraction value.
Described OCT system is the high-resolution depth scan OCT system of full eye imaging.
Described optical path-tracing method realizes by ZEMAX optical path-tracing simulation softward.
Described OCT system is comprised of anterior ocular segment depth scan OCT and oculi posterior segment OCT, described anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, described oculi posterior segment OCT can to retina image-forming, obtain the OCT image of full eye by synchronous scanning, sample than double focusing probe, image acquisition and image integration technology.
Described OCT image is two dimensional image or 3-D view, clear each refractive interface and the retina of showing of described OCT image.
Described refracting media comprises cornea, anterior chamber and crystalline lens.
Described peripheral refraction measuring method based on the OCT technology, wherein the method for image processing comprises:
At first image is carried out noise reduction process;
Adopt boundary extraction algorithm, the border of each organizational interface is extracted, if 3-D view on the basis of Boundary Extraction, also need carry out image registration and three-dimensional reconstruction;
Obtain form and the range information at each interface according to the boundary information that extracts.
The invention has the beneficial effects as follows: the method only need to be by the disposable OCT image that obtains full eye of high-resolution OCT system of full eye imaging, and follow-up realization can be passed through software processes, and the method is measured fast accurate.
Description of drawings
Accompanying drawing 1 is the schematic diagram of the high-resolution OCT system of full eye imaging.
Accompanying drawing 2 is the schematic diagram of the OCT two dimensional image of full eye.
Accompanying drawing 3 is each refractive interface and amphiblestroid form schematic diagram.
The specific embodiment
As Fig. 1, Fig. 2 and shown in Figure 3: a kind of peripheral refraction measuring method based on the OCT technology, described method comprises:
Utilize the high-resolution depth scan OCT system of full eye imaging, this OCT system is comprised of anterior ocular segment depth scan OCT and oculi posterior segment OCT, anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, oculi posterior segment OCT can be to retina image-forming, by synchronous scanning, sample than double focusing probe, image acquisition and image integration technology, intraocular refracting media (comprising cornea, anterior chamber and crystalline lens) and retina are carried out one-time imaging, obtain OCT two dimension or the 3-D view of full eye, clear each refractive interface and the retina of showing of OCT image.
Utilize image processing software to analyze described OCT image, at first image is carried out noise reduction process; Three-dimensional volumetric image adopts boundary extraction algorithm again, the border of each organizational interface extracted, if on the basis of Boundary Extraction, also need be carried out image registration and three-dimensional reconstruction;
Obtain each refractive interface and amphiblestroid form and range information according to the boundary information that extracts.The curvature, corneal central thickness, anterior chamber depth, lens thickness and the vitreous chamber thickness that comprise curvature, the crystalline lens rear surface 4 of curvature, the anterior surface of lens 3 of curvature, the posterior surface of cornea 2 of anterior surface of cornea 1.
Then utilize the optical path-tracing method, as ZEMAX optical path-tracing simulation softward, obtain the route 6 of central refraction power of boresight direction and the peripheral refraction power route 7 that becomes unspecified angle with the described optical axis.
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central refraction power, obtain thus the peripheral refraction value.
In order to obtain the imaging of larger pupil scope, to the experimenter can mydriasis after imaging, do not affect the measurement of peripheral refraction.The method only need to be by the disposable OCT image that obtains full eye of high-resolution OCT system of full eye imaging, and follow-up realization can pass through software processes, avoided the measurement point of existing peripheral refraction measuring method many, speed slowly, locate the shortcomings such as inaccuracy.
Claims (8)
1. peripheral refraction measuring method based on the OCT technology, described method comprises:
Utilize the OCT system to carry out one-time imaging to intraocular refracting media and retina, obtain the OCT image;
Utilize image processing software to analyze described OCT image, to obtain each refractive interface and amphiblestroid form and range information;
Utilize the optical path-tracing method, obtain the central refraction power of boresight direction and the peripheral refraction power that becomes unspecified angle with the described optical axis;
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central refraction power, obtain thus the peripheral refraction value.
2. the peripheral refraction measuring method based on the OCT technology according to claim 1, wherein said OCT system is the high-resolution depth scan OCT system of full eye imaging.
3. the peripheral refraction measuring method based on the OCT technology according to claim 1, wherein said optical path-tracing method realizes by ZEMAX optical path-tracing simulation softward.
4. the peripheral refraction measuring method based on the OCT technology according to claim 1 and 2, described OCT system is comprised of anterior ocular segment depth scan OCT and oculi posterior segment OCT, described anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, described oculi posterior segment OCT can to retina image-forming, obtain the OCT image of full eye by synchronous scanning, sample than double focusing probe, image acquisition and image integration technology.
5. according to claim 1 or 4 described peripheral refraction measuring methods based on the OCT technology, described OCT image is two dimensional image or 3-D view, clear each refractive interface and the retina of showing of described OCT image.
6. the peripheral refraction measuring method based on the OCT technology according to claim 1, described refracting media comprises cornea, anterior chamber and crystalline lens.
7. according to claim 1-3, the described peripheral refraction measuring method based on the OCT technology of any one in 5-6, wherein the method processed of image comprises:
At first image is carried out noise reduction process;
Adopt boundary extraction algorithm, the border of each organizational interface is extracted, if 3-D view on the basis of Boundary Extraction, also need carry out image registration and three-dimensional reconstruction;
Obtain form and the range information at each interface according to the boundary information that extracts.
8. the peripheral refraction measuring method based on the OCT technology according to claim 4, wherein the method processed of image comprises:
At first image is carried out noise reduction process;
Adopt boundary extraction algorithm, the border of each organizational interface is extracted, if 3-D view on the basis of Boundary Extraction, also need carry out image registration and three-dimensional reconstruction;
Obtain form and the range information at each interface according to the boundary information that extracts.
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| CN103519781A (en) * | 2013-09-26 | 2014-01-22 | 澳门科技大学 | Method and device for eliminating reflected light at cornea center of anterior segment optical coherence tomographic image |
| CN104050664A (en) * | 2014-06-09 | 2014-09-17 | 杭州电子科技大学 | Method for classifying eye anterior chamber angle opening degrees in multi-feature mode based on OCT image |
| CN104688178A (en) * | 2015-03-05 | 2015-06-10 | 温州医科大学 | Keratectasia measurement method based on optical CT |
| CN104905763A (en) * | 2015-06-18 | 2015-09-16 | 苏州四海通仪器有限公司 | Optometry device capable of measuring paracentral defocus |
| CN111601538A (en) * | 2019-01-16 | 2020-08-28 | 株式会社拓普康 | Ophthalmic device |
| CN112120666A (en) * | 2020-10-14 | 2020-12-25 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
| CN115553714A (en) * | 2021-07-02 | 2023-01-03 | 深圳盛达同泽科技有限公司 | Optometry equipment |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519781A (en) * | 2013-09-26 | 2014-01-22 | 澳门科技大学 | Method and device for eliminating reflected light at cornea center of anterior segment optical coherence tomographic image |
| CN103519781B (en) * | 2013-09-26 | 2015-06-17 | 澳门科技大学 | Method and device for eliminating reflected light at cornea center of anterior segment optical coherence tomographic image |
| CN104050664A (en) * | 2014-06-09 | 2014-09-17 | 杭州电子科技大学 | Method for classifying eye anterior chamber angle opening degrees in multi-feature mode based on OCT image |
| CN104688178A (en) * | 2015-03-05 | 2015-06-10 | 温州医科大学 | Keratectasia measurement method based on optical CT |
| US10478062B2 (en) | 2015-06-18 | 2019-11-19 | Suzhou Seehitech Equipments Co., Ltd | Optometry apparatus capable of measuring para-central defocus |
| WO2016202312A1 (en) * | 2015-06-18 | 2016-12-22 | 苏州四海通仪器有限公司 | Para-central defocusing measuring optometry apparatus |
| CN104905763A (en) * | 2015-06-18 | 2015-09-16 | 苏州四海通仪器有限公司 | Optometry device capable of measuring paracentral defocus |
| CN111601538A (en) * | 2019-01-16 | 2020-08-28 | 株式会社拓普康 | Ophthalmic device |
| CN111601538B (en) * | 2019-01-16 | 2021-03-09 | 株式会社拓普康 | Ophthalmic device |
| CN112120666A (en) * | 2020-10-14 | 2020-12-25 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
| CN112120666B (en) * | 2020-10-14 | 2024-06-11 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
| CN115553714A (en) * | 2021-07-02 | 2023-01-03 | 深圳盛达同泽科技有限公司 | Optometry equipment |
| CN115553714B (en) * | 2021-07-02 | 2024-05-31 | 深圳盛达同泽科技有限公司 | Optometry equipment |
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Inventor after: Yuan Yimin Inventor after: Lv Fan Inventor after: Shen Meixiao Inventor after: Zhu Dexi Inventor before: Yuan Yiming Inventor before: Lv Fan Inventor before: Shen Meixiao Inventor before: Zhu Dexi |
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